Approximate Cost Reference List i for Antihyperglycemic Agents

Size: px
Start display at page:

Download "Approximate Cost Reference List i for Antihyperglycemic Agents"

Transcription

1 Alpha Glucosidase Inhibitor Acarbose (Glucobay ) Biguanides Metformin (Glucophage, generic) Metformin ER (Glumetza ) Approximate Cost Reference List i for Antihyperglycemic Agents Incretin Agents - DPP-4 inhibitors Alogliptin (Nesina ) 100 mg $ 0.41/Tab mg three times a day 50 mg $ 0.29/Tab mg per day in divided doses $ 0.05/Tab mg per day in divided doses $ 0.06/Tab mg per day $ 0.63/Tab mg per day $ 1.27/Tab 6.25 mg 6.25 mg once daily (depending on renal function) $ 2.84/Tab 12.5 mg 12.5 mg once daily (depending on renal function) $ 2.84/Tab 25 mg 25 mg once daily (depending on renal function) $ 2.84/Tab Linagliptin (Trajenta ) 5 mg 5 mg once daily $ 2.60/Tab Saxagliptin (Onglyza ) Sitagliptin (Januvia ) Incretin Agents GLP-1 receptor agonists 2.5 mg mg once daily $ 2.57/Tab 5 mg mg once daily $ 3.09/Tab 25 mg 25 mg once daily (depending on renal function) $ 3.20/Tab 50 mg 50 mg once daily (depending on renal function) $ 3.20/Tab 100 mg 100 mg once daily $ 3.20/Tab Albiglutide (Eperzan ) N/A N/A N/A Exenatide (Byetta ) 5 mcg prefilled pen (250 µg/ml) 10 mcg prefilled pen (250 µg/ml) 10 mcg twice a day 10 mcg twice a day $ 2.50/5 mcg dose (supplied as prefilled pen) $ 2.50/10 mcg dose (supplied as prefilled pen) Liraglutide (Victoza ) 6 mg/ml mg once daily $ 2.98/0.6 mg dose $ 5.96/1.2 mg dose $ 8.95/1.8 mg dose (supplied as prefilled pens)

2 Insulin Secretagogues Sulfonylureas Gliclazide (Diamicron, generic) Gliclazide (Diamicron MR, generic) Glimepiride (Amaryl, generic) Glyburide (Diabeta, generic) 80 mg mg per day (doses > 160mg should be twice a day) $ 0.09/Tab 30 mg mg once daily $ 0.09/Tab 60 mg mg once daily $ 0.21/Tab 1 mg 2 mg 4 mg 2.5 mg mg once daily $ 0.04/Tab 5 mg mg once daily $ 0.06/Tab Note: chlorpropamide and tolbutamide are still available in Canada, but rarely used Insulin Secretagogues Meglitinides Nateglinide (Starlix) (Discontinued) Repaglinide (Gluconorm, generic) 60 mg 120 mg three times a day $ 0.60/Tab 120 mg 120 mg three times a day $ 0.63/Tab 0.5 mg 1 mg 2 mg $ 0.15/Tab $ 0.16/Tab $ 0.18/Tab Sodium Glucose co-transporter 2 inhibitors (SGLT2) Canagliflozin(Invokana ) 100 mg mg once daily $ 2.84/Tab 300 mg mg once daily $ 2.84/Tab Dapagliflozin(Forxiga ) 5 mg 5-10 mg once daily $ 2.84/Tab 10 mg 5-10 mg once daily $ 2.84/Tab Empagliflozin (Jardiance ) Thiazolidinediones Pioglitazone (Actos) generic Rosiglitazone (Avandia ) 10 mg mg once daily $ 2.84/Tab 25 mg mg once daily $ 2.84/Tab 15 mg mg once daily $ 1.29/Tab 30 mg mg once daily $ 1.81/Tab 45 mg Maximum daily dose $ 2.72/Tab 2 mg 4-8 mg daily as a single or as a divided dose 4 mg 4-8 mg daily as a single or as a divided dose $ 2.34/Tab 8 mg 4-8 mg daily as a single or as a divided dose $ 3.35/Tab

3 Weight Loss Agent Orlistst (Xenical ) 120 mg tab 120 mg three times a day $ 1.78/Tab Combination Products Alogliptin/Metformin (Kazano ) $ 1.28/Tab Linagliptin/Metformin (Jentadueto ) Rosiglitazone/Metformin (AvandaMet ) Saxagliptin/Metformin (Komboglyze ) Sitagliptin/Metformin (Janumet ) Sitagliptan/Metformin Extended Release Formula (Janumet XR ) 2 mg/ 2 mg/ 4 mg/ 4 mg/ Starting dose of 2 mg/ may increase to a Starting dose of 2 mg/ may increase to a Starting dose of 2 mg/ may increase to a Starting dose of 2 mg/ may increase to a Usual dose 2 tablets once daily Usual dose 2 tablets once daily $ 1.28/Tab $ 1.28/Tab $ 1.26/Tab $ 1.73/Tab $ 1.83/Tab 100 mg/ Usual dose 2 tablets once daily

4 PRANDIAL (BOLUS) INSULINS Rapid-Acting Insulin Analogues Aspart (NovoRapid ) Glulisine (Apidra ) Lispro (Humalog ) Lispro 200 units/ml (Humalog ) Short-Acting Insulin regular (Humulin - R) Insulin regular (Novolin ge Toronto) Approximate Cost Reference for Insulins ii 200 units/ml (600 units/prefilled pen) USUAL MAINTENANCE DOSE OR USUAL DOSAGE RANGE FOR PEN CARTRIDGE FOR PRE- FILLED PEN $ 0.043/unit $ 0.044/unit $ 0.036/unit $ 0.036/unit $ 0.041/unit $ 0.040/unit N/A $ 0.033/unit N/A $ 0.037/unit Note: Pork regular insulin (Hypurin Regular Insulin Pork) and pork isophane insulin (Hypurin NPH Insulin Isophane) are available but rarely used. BASAL INSULINS Intermediate-acting Insulin NPH (Humulin - N) Insulin NPH (Novolin ge NPH) Long-acting Basal Insulin Analogues Determir (Levemir ) Glargine (Lantus ) Glargine 300 units/ml (Toujeo ) 300 units/ml (450 units/prefilled pen) $ 0.033/unit $ 0.033/unit $ 0.075/unit $ 0.078/unit $ 0.067/unit $ 0.067/unit N/A $ 0.064/unit Note: Pork regular insulin (Hypurin Regular Insulin Pork) and pork isophane insulin (Hypurin NPH Insulin Isophane) are available but rarely used.

5 PREMIXED INSULINS Premixed Regular Insulin NPH Insulin regular/nph (Humulin 30/70) Insulin regular/nph (Novolin ge 30/70, 40/60, 50/50) Premixed Insulin Analogues USUAL MAINTENANCE DOSE OR USUAL DOSAGE RANGE FOR PEN CARTRIDGE $ 0.028/unit N/A FOR PRE- FILLED PEN Aspart 30%/aspart protamine 70% (NovoMix 30) $ 0.040/unit N/A Lispro 25%/lispro protamine 75% (Humalog Mix25 ) $ 0.041/unit $ 0.040/unit Lispro 50%/lispro protamine 50% (Humalog Mix50 ) $ 0.040/unit $ 0.040/unit * Approximate unit drug cost not including dispensing/professional fee and pharmacy mark-up. Approximate Canadian Cost average is the weighted wholesale cost (including a wholesale mark-up charge) to the pharmacy before dispensing. i The listed medications represent both the classes and the agents that are most commonly used in primary care practices. It is not meant to be an exhaustive list, and is intended only as a guide for the family physician. ii Insulin prices are based on the pen cartridge price and corresponding vial price would be marginally less Updated October 2015 guidelines.diabetes.ca diabetes.ca BANTING ( )

Antihyperglycemic Agents Comparison Chart

Antihyperglycemic Agents Comparison Chart Parameter Metformin Sulfonylureas Meglitinides Glitazones (TZD s) Mechanism of Action Efficacy (A1c Reduction) Hepatic glucose output Peripheral glucose uptake by enhancing insulin action insulin secretion

More information

What is Diabetes? Diabetes Medications AGENDA

What is Diabetes? Diabetes Medications AGENDA Diabetes Medications AGENDA 1. What is Diabetes? 2. The Four Key Players 3. How medications can help 4. Blood Glucose Monitoring 5. Treatment of Low Blood Sugars What is Diabetes? 1 What IS Diabetes? Diabetes

More information

Overview of Diabetes Medications

Overview of Diabetes Medications Overview of Diabetes Medications Marie Frazzitta DNP, FNP c, CDE, MBA Senior Director of Disease Management North Shore LIJ Health Systems Normal Glucose Metabolism Insulin is produced by beta cells in

More information

Comparing Medications for Adults With Type 2 Diabetes Focus of Research for Clinicians

Comparing Medications for Adults With Type 2 Diabetes Focus of Research for Clinicians Clinician Research Summary Diabetes Type 2 Diabetes Comparing Medications for Adults With Type 2 Diabetes Focus of Research for Clinicians A systematic review of 166 clinical studies published between

More information

10/30/2012. Anita King, DNP, RN, FNP, CDE, FAADE Clinical Associate Professor University of South Alabama Mobile, Alabama

10/30/2012. Anita King, DNP, RN, FNP, CDE, FAADE Clinical Associate Professor University of South Alabama Mobile, Alabama Faculty Medications for Diabetes Satellite Conference and Live Webcast Wednesday, November 7, 2012 2:00 4:00 p.m. Central Time Anita King, DNP, RN, FNP, CDE, FAADE Clinical Associate Professor University

More information

Diabetes Medications. Minal Patel, PharmD, BCPS

Diabetes Medications. Minal Patel, PharmD, BCPS Diabetes Medications Minal Patel, PharmD, BCPS Objectives Examine advantages and disadvantages of oral anti-hyperglycemic medications Describe the differences between different classes of insulin Explore

More information

Type 2 Diabetes Medicines: What You Need to Know

Type 2 Diabetes Medicines: What You Need to Know Type 2 Diabetes Medicines: What You Need to Know Managing diabetes is complex because many hormones and body processes are at work controlling blood sugar (glucose). Medicines for diabetes include oral

More information

FYI: (Acceptable range for blood glucose usually 70-110 mg/dl. know your institutions policy.)

FYI: (Acceptable range for blood glucose usually 70-110 mg/dl. know your institutions policy.) How Insulin Works: Each type of insulin has an onset, a peak, and a duration time. Onset is the length of time before insulin reaches the bloodstream and begins lowering blood Peak is the time during which

More information

Mary Bruskewitz APN, MS, RN, BC-ADM Clinical Nurse Specialist Diabetes

Mary Bruskewitz APN, MS, RN, BC-ADM Clinical Nurse Specialist Diabetes Mary Bruskewitz APN, MS, RN, BC-ADM Clinical Nurse Specialist Diabetes Objectives Pathophysiology of Diabetes Acute & Chronic Complications Managing acute emergencies Case examples 11/24/2014 UWHealth

More information

Diabetes Update Lanita S. Shaverd, Pharm.D. Director, UAMS 12 th Street Health and Wellness Center Assistant Professor, UAMS College of Pharmacy

Diabetes Update Lanita S. Shaverd, Pharm.D. Director, UAMS 12 th Street Health and Wellness Center Assistant Professor, UAMS College of Pharmacy Objectives Review oral medications used for the treatment of diabetes Explain how to effectively combine oral diabetes medications for optimal results Discuss insulins and non-insulin injectable diabetes

More information

Acarbose INITIAL: 25 mg PO TID ($45) Miglitol INITIAL: 25 mg PO TID ($145)

Acarbose INITIAL: 25 mg PO TID ($45) Miglitol INITIAL: 25 mg PO TID ($145) PL Detail-Document #310601 This PL Detail-Document gives subscribers additional insight related to the Recommendations published in PHARMACIST S LETTER / PRESCRIBER S LETTER June 2015 Drugs for Type 2

More information

Medicines for Type 2 Diabetes A Review of the Research for Adults

Medicines for Type 2 Diabetes A Review of the Research for Adults Medicines for Type 2 Diabetes A Review of the Research for Adults Is This Information Right for Me? Yes, if: Your doctor or health care provider has told you that you have type 2 diabetes and have high

More information

INSULIN INTENSIFICATION: Taking Care to the Next Level

INSULIN INTENSIFICATION: Taking Care to the Next Level INSULIN INTENSIFICATION: Taking Care to the Next Level By J. Robin Conway M.D., Diabetes Clinic, Smiths Falls, ON www.diabetesclinic.ca Type 2 Diabetes is an increasing problem in our society, due largely

More information

DIABETES MEDICATIONS

DIABETES MEDICATIONS CLINICAL POLICY DIABETES MEDICATIONS Policy Number: PHARMACY 242.8 T2 Effective Date: January 1, 2016 Table of Contents CONDITIONS OF COVERAGE... COVERAGE RATIONALE... BENEFIT CONSIDERATIONS... BACKGROUND...

More information

DIABETES EDUCATION. *Read package insert each time you refill your medications in case there is new information SULFONYLUREAS

DIABETES EDUCATION. *Read package insert each time you refill your medications in case there is new information SULFONYLUREAS DIABETES EDUCATION *Read package insert each time you refill your medications in case there is new information SULFONYLUREAS ACTION: Sulfonylureas stimulate the pancreas to make more insulin (pancreas

More information

A NEW TAKE ON DIABETES MEDICATIONS: RISKS AND BENEFITS, OLD MEDICATIONS VERSUS NEW, AND NEW INFORMATION ON OLD MEDICATIONS

A NEW TAKE ON DIABETES MEDICATIONS: RISKS AND BENEFITS, OLD MEDICATIONS VERSUS NEW, AND NEW INFORMATION ON OLD MEDICATIONS A NEW TAKE ON DIABETES MEDICATIONS: RISKS AND BENEFITS, OLD MEDICATIONS VERSUS NEW, AND NEW INFORMATION ON OLD MEDICATIONS JESSICA CONKLIN, PHARMD, PHC, BCACP, CDE VISITING ASSISTANT PROFESSOR UNM COLLEGE

More information

Diabetes Treatments: Options for Insulin Delivery. Bonnie Pepon, RN, BSN, CDE Certified Diabetes Educator Conemaugh Diabetes Institute

Diabetes Treatments: Options for Insulin Delivery. Bonnie Pepon, RN, BSN, CDE Certified Diabetes Educator Conemaugh Diabetes Institute Diabetes Treatments: Options for Insulin Delivery Bonnie Pepon, RN, BSN, CDE Certified Diabetes Educator Conemaugh Diabetes Institute Diabetes 21 million people in the U.S. have diabetes $132 billion each

More information

Type 2 Diabetes Medications: SGLT2 Inhibitors

Type 2 Diabetes Medications: SGLT2 Inhibitors Type 2 Diabetes Medications: SGLT2 Inhibitors SGLT2 inhibitors are a class of type 2 diabetes medications used along with diet and exercise to lower blood glucose How are they taken? SGLT2 inhibitors is

More information

Fundamentals of Diabetes Care Module 5, Lesson 1

Fundamentals of Diabetes Care Module 5, Lesson 1 Module 5, Lesson 1 Fundamentals of Diabetes Care Module 5: Taking Medications Healthy Eating Being Active Monitoring Taking Medication Problem Solving Healthy Coping Reducing Risks Foundations For Control

More information

Antidiabetic Drugs. Mosby items and derived items 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc.

Antidiabetic Drugs. Mosby items and derived items 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. Antidiabetic Drugs Mosby items and derived items 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. Diabetes Mellitus Two types Type 1 Type 2 Type 1 Diabetes Mellitus Lack of insulin production

More information

Anti-Diabetic Agents. Chapter. Charles Ruchalski, PharmD, BCPS. Drug Class: Biguanides. Introduction. Metformin

Anti-Diabetic Agents. Chapter. Charles Ruchalski, PharmD, BCPS. Drug Class: Biguanides. Introduction. Metformin Chapter Anti-Diabetic Agents 2 Charles Ruchalski, PharmD, BCPS Drug Class: Biguanides The biguanide metformin is the drug of choice as initial therapy for a newly diagnosed patient with type 2 diabetes

More information

Diabetes Medications March 12, 2016

Diabetes Medications March 12, 2016 Innovative Approaches to Diabetes Care Diabetes Education Center of the Midlands Diabetes Medications March 12, 2016 Pam Wollenburg, APRN, CDE CHI Health St Elizabeth Diabetes Center Excellence in Diabetes

More information

Medications for Type 2 Diabetes

Medications for Type 2 Diabetes Main Page Risk Factors Symptoms Diagnosis Treatment Screening Complications Reducing Your Risk Talking to Your Doctor Living With Type 2 Diabetes Resource Guide Medications for Type 2 Diabetes by Karen

More information

Diabetes Mellitus Pharmacology Review

Diabetes Mellitus Pharmacology Review Diabetes Mellitus Pharmacology Review Hien T. Nguyen, Pharm.D., BCPS Clinical Pharmacist Specialist AtlantiCare Regional Medical Center E-Mail: HienT.Nguyen@atlanticare.org Objectives 1. Review the epidemiology

More information

New Non-Insulin Therapies for Type 2 Diabetes Mellitus

New Non-Insulin Therapies for Type 2 Diabetes Mellitus New Non-Insulin Therapies for Type 2 Diabetes Mellitus Ally P.H. Prebtani Associate Professor of Medicine Internal Medicine, Endocrinology & Metabolism McMaster University Canada Disclosure Relationships

More information

Add: 2 nd generation sulfonylurea or glinide or Add DPP-4 inhibitor Start or intensify insulin therapy if HbA1c goals not achieved with the above

Add: 2 nd generation sulfonylurea or glinide or Add DPP-4 inhibitor Start or intensify insulin therapy if HbA1c goals not achieved with the above Guidelines for Type Diabetes - Diagnosis Fasting Plasma Glucose (confirm results if borderline) HbAIC Normal FPG < 00 < 5.5 Impaired Fasting Glucose (IFG) 00 to < 5.7%-.5% Diabetes Mellitus (or random

More information

Noninsulin Diabetes Medications Summary Chart Medications marked with an asterisk (*) can cause hypoglycemia MED GROUP DESCRIPTOR

Noninsulin Diabetes Medications Summary Chart Medications marked with an asterisk (*) can cause hypoglycemia MED GROUP DESCRIPTOR Noninsulin Diabetes Medications Summary Chart Medications marked with an asterisk (*) can cause MED GROUP DESCRIPTOR INSULIN SECRETAGOGUES Sulfonylureas* GLYBURIDE* (Diabeta) (Micronase) MICRONIZED GLYBURIDE*

More information

Making Clinical Sense of Diabetes Medications. Types of Diabetes. Pathophysiology. Beta Cell Function & Glucagon

Making Clinical Sense of Diabetes Medications. Types of Diabetes. Pathophysiology. Beta Cell Function & Glucagon Making Clinical Sense of Diabetes Medications Kathy Reily, RD, CDE Prince William Hospital Diabetes Program Coordinator Virginia Dietetic Association April 4, 2011 Types of Diabetes Type 1 DM = Beta Cell

More information

Diabetes may be classified as. i) Type - I Diabetes mellitus. Type - II Diabetes mellitus. Type - 1.5 Diabetes mellitus. Gestational Diabetes INSULIN

Diabetes may be classified as. i) Type - I Diabetes mellitus. Type - II Diabetes mellitus. Type - 1.5 Diabetes mellitus. Gestational Diabetes INSULIN HYPOGLYCEMIC AGENT Diabetes mellitus is a chronic metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting

More information

What I need to know about. Diabetes Medicines. National Diabetes Information Clearinghouse

What I need to know about. Diabetes Medicines. National Diabetes Information Clearinghouse What I need to know about Diabetes Medicines National Diabetes Information Clearinghouse What I need to know about Diabetes Medicines Contents What do diabetes medicines do?... 1 What targets are recommended

More information

Medicines Used to Treat Type 2 Diabetes

Medicines Used to Treat Type 2 Diabetes Goodman Diabetes Service Medicines Used to Treat Type 2 Diabetes People who have type 2 diabetes may need to take medicine to help lower their blood glucose, in addition to being active & choosing healthy

More information

Treatment of Type 2 Diabetes

Treatment of Type 2 Diabetes Improving Patient Care through Evidence Treatment of Type 2 Diabetes This information is based on a comprehensive review of the evidence for best practices in the treatment of type 2 diabetes and is sponsored

More information

Diabetes Management. Lisa Pezik RN, BScN Clinical Educator

Diabetes Management. Lisa Pezik RN, BScN Clinical Educator Diabetes Management Lisa Pezik RN, BScN Clinical Educator Objectives Review the physiology of diabetes. Compare the difference between hypoglycemia and hyperglycemia. Learn how to best monitor diabetes.

More information

Targeting the Kidney. Renal Glucose Transport 11/4/2015. Non insulin Agents Available IBITORS. Chao EC, et al. Nat Rev Drug Discovery. 2010;9:551 559.

Targeting the Kidney. Renal Glucose Transport 11/4/2015. Non insulin Agents Available IBITORS. Chao EC, et al. Nat Rev Drug Discovery. 2010;9:551 559. SGLT-2i and DPP-IVi in the Management of Diabetes Mellitus Type 2 Abel Alfonso, D.O., F.A.C.E. Endocrinologist November 5, 2015 DIABETES: CURRENT RATES AND PROJECTIONS CDC Press Release 2010: 1 in 3 adults

More information

TREATMENT STRATEGIES FOR MANAGING TYPE 2 DIABETES MELLITUS. Friday, August 16, 13

TREATMENT STRATEGIES FOR MANAGING TYPE 2 DIABETES MELLITUS. Friday, August 16, 13 TREATMENT STRATEGIES FOR MANAGING TYPE 2 DIABETES MELLITUS 1 Heather Healy, FNP-BC Martha Shelver, CS, ACNP-BC Saint Alphonsus Regional Medical Center 2 OBJECTIVES 3 Review the current management algorithms

More information

TYPE 2 DIABETES ADA-EASD TREATMENT GUIDELINES AND 2015 NEW UPDATES 1,2

TYPE 2 DIABETES ADA-EASD TREATMENT GUIDELINES AND 2015 NEW UPDATES 1,2 TYPE 2 DIABETES ADA-EASD TREATMENT GUIDELINES AND 2015 NEW UPDATES 1,2 The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) released a position statement

More information

Indications for Insulin Initiation. Starting Insulin Step 1 - Preparation. Starting Insulin Step 2

Indications for Insulin Initiation. Starting Insulin Step 1 - Preparation. Starting Insulin Step 2 Indications for Insulin Initiation Patient Information Starting Insulin Step 1 - Preparation Physician Information Starting Insulin Step 2 Primarily fasting/pre-meal hyperglycemia +/- post-meal hyperglycemia

More information

Medication Policy Manual

Medication Policy Manual Medication Policy Manual Topic: Branded SGLT2-Inhibitor-Containing Medications: - canagliflozin (Invokana, Invokamet ); - dapagliflozin (Farxiga, Xigduo XR); - empagliflozin (Jardiance, Glyxambi, Synjardy

More information

Class Update: Diabetes Medications. Month/Year of Review: September 2014 End date of literature search: August 2014

Class Update: Diabetes Medications. Month/Year of Review: September 2014 End date of literature search: August 2014 Copyright 2012 Oregon State University. All Rights Reserved Drug Use Research & Management Program Oregon State University, 500 Summer Street NE, E35, Salem, Oregon 97301-1079 Phone 503-947-5220 Fax 503-947-1119

More information

medications for type 2 diabetes

medications for type 2 diabetes Talking diabetes No.25 Revised August 2010 medications for type 2 diabetes People with type 2 diabetes are often given medications including insulin to help control their blood glucose levels. Most of

More information

Type 2 Diabetes Mellitus 2014

Type 2 Diabetes Mellitus 2014 Type 2 Diabetes Mellitus 2014 Michael T. McDermott MD Director, Endocrinology and Diabetes Practice University of Colorado Hospital Michael.mcdermott@ucdenver.edu Disclosure Michael McDermott MD No Conflict

More information

Antidiabetic Agents. Chapter. Biguanides

Antidiabetic Agents. Chapter. Biguanides ajt/shutterstock, Inc. Chapter 2 Antidiabetic Agents Charles Ruchalski, PharmD, BCPS Biguanides Introduction For newly diagnosed patients with type 2 diabetes, the biguanide metformin is the drug of choice

More information

Diabetes Mellitus: Pharmacology and Disease Management

Diabetes Mellitus: Pharmacology and Disease Management Diabetes Mellitus: Pharmacology and Disease Management Michael King, MD Assistant Professor Residency Program Director University of Kentucky Dept. of Family & Community Medicine Objectives 1. Compare

More information

INSULINThere are. T y p e 1 T y p e 2. many different insulins for

INSULINThere are. T y p e 1 T y p e 2. many different insulins for T y p e 1 T y p e 2 INSULINThere are many different insulins for Characteristics The three characteristics of insulin are: Onset. The length of time before insulin reaches the bloodstream and begins lowering

More information

Diabetes Medications in Older Adults

Diabetes Medications in Older Adults . Diabetes Medications in Older Adults Overview General Approach DM in Frail, Older Adults Medications for CV Risk Reduction Glycemic Targets Oral Medications for Glycemic Control Insulin Cases Age-related

More information

Information for Patients

Information for Patients Information for Patients Guidance for Diabetic Persons having bowel preparation for a flexible sigmoidoscopy or a colonoscopy or a combined gastroscopy and colonoscopy This guidance is provided to assist

More information

Bulletin Independent prescribing information for NHS Wales

Bulletin Independent prescribing information for NHS Wales Bulletin Independent prescribing information for NHS Wales Type 2 diabetes: newer medicines and insulin analogues First-line management of hyperglycaemia in patients with type 2 diabetes, when diet and

More information

TYPE 2 DIABETES CRITERIA FOR REFERRAL TO LEVEL 2 OOHS

TYPE 2 DIABETES CRITERIA FOR REFERRAL TO LEVEL 2 OOHS TYPE 2 DIABETES CRITERIA FOR REFERRAL TO LEVEL 2 OOHS The aim of the Diabetes level 2 service is to provide a high quality service for safe initiation and optimization of injectable therapy within GP networks.

More information

Patient Guide. for Self Monitoring of Blood Glucose (SMBG) in Diabetes

Patient Guide. for Self Monitoring of Blood Glucose (SMBG) in Diabetes Patient Guide for Self Monitoring of Blood Glucose (SMBG) in Diabetes The aim of this leaflet is to provide you with general information on how often and when you should be testing your blood glucose This

More information

Guidelines for Type 2 Diabetes Diagnosis

Guidelines for Type 2 Diabetes Diagnosis Guidelines for Type 2 Diabetes Diagnosis Fasting Plasma Glucose (in asymptomatic individuals, repeat measurement to confirm the test) Normal FPG < 100 2-hr OGTT < 140 HbA1C < 5.5% Impaired Fasting Glucose

More information

we have to keep up. Timothy S. Reid, M.D. Mercy Diabetes Center Janesville, WI Entity Activity Financial Consideration Comments

we have to keep up. Timothy S. Reid, M.D. Mercy Diabetes Center Janesville, WI Entity Activity Financial Consideration Comments Timothy S. Reid, M.D. Mercy Diabetes Center Janesville, WI Entity Activity Financial Consideration Comments Novo Nordisk Speaker/Consultant Speaker Fees/Honoraria Sanofi-Aventis Speaker/Consultant Speaker

More information

Cara Liday, PharmD, CDE Associate Professor, Idaho State University Clinical Pharmacist and CDE, InterMountain Medical Center Pocatello, ID The planners and presenter have disclosed no conflict of interest,

More information

Diabetes Medications. Your Guide to. Easy-to-understand information about your diabetes medications

Diabetes Medications. Your Guide to. Easy-to-understand information about your diabetes medications A supplement to Diabetes Dialogue, an official publication of the Canadian Diabetes Association Your Guide to Diabetes Medications Easy-to-understand information about your diabetes medications How they

More information

medications for type 2 diabetes

medications for type 2 diabetes Talking diabetes No.25 Revised 2012 medications for type 2 diabetes People with type 2 diabetes are often given medications including insulin to help manage their blood glucose levels. Most of these medications

More information

Traditional and Novel Diabetes Medications

Traditional and Novel Diabetes Medications Prevalence of Diabetes in the United States, 2011 Traditional and Novel Diabetes Medications Total: 25.8 million people 8.3% of the population Diagnosed: 18.8 million people Undiagnosed: 7 million people

More information

Pills for Type 2 Diabetes. A Guide for Adults

Pills for Type 2 Diabetes. A Guide for Adults Pills for Type 2 Diabetes A Guide for Adults December 2007 Fast Facts on Diabetes Pills n Different kinds of diabetes pills work in different ways to control blood sugar (blood glucose). n All the diabetes

More information

Primary Care Type 2 Diabetes Update

Primary Care Type 2 Diabetes Update Primary Care Type 2 Diabetes Update May 16, 2014 Presented by: Barb Risnes APRN, BC-ADM, CDE Objectives: Discuss strategies to address common type 2 diabetes patient management challenges Review new pharmacological

More information

Diabetes Medications at the End of Life. Goals and Objectives. Diabetes. Type 2 Diabetes Mellitus. Types of Diabetes

Diabetes Medications at the End of Life. Goals and Objectives. Diabetes. Type 2 Diabetes Mellitus. Types of Diabetes Diabetes Medications at the End of Life Paul J. Schmidt Jr., R.Ph., M.S. Clinical Supervisor HospiScript Services pschmidt@hospiscript.com Goals and Objectives Describe the Current Impact of Diabetes Mellitus

More information

My Doctor Says I Need to Take Diabetes Pills and Insulin What Do I Do Now? BD Getting Started Combination Therapy

My Doctor Says I Need to Take Diabetes Pills and Insulin What Do I Do Now? BD Getting Started Combination Therapy My Doctor Says I Need to Take Diabetes Pills and Insulin What Do I Do Now? BD Getting Started Combination Therapy Combination Therapy Adding medication and/or insulin to better manage diabetes What is

More information

Diabetes: When To Treat With Insulin and Treatment Goals

Diabetes: When To Treat With Insulin and Treatment Goals Diabetes: When To Treat With Insulin and Treatment Goals Lanita. S. White, Pharm.D. Director, UAMS 12 th Street Health and Wellness Center Assistant Professor of Pharmacy Practice, UAMS College of Pharmacy

More information

6/22/2015. New medicines for type 2 diabetes when do you use them

6/22/2015. New medicines for type 2 diabetes when do you use them New medicines for type 2 diabetes when do you use them 1. Oral Secretagogues (e.g. sulfonylureas) 2. Metformin 3. Alpha glucosidase inhibitors 4. Thiazolidinediones 5. GLP-1 receptor agonists 6. DPP-4

More information

The prevalence of diabetes in the United States in

The prevalence of diabetes in the United States in Medical Management of Type 2 Diabetes Celia Levesque, CNS-BC ABSTRACT More than 20 million Americans have type 2 diabetes. Managing blood glucose is an important component in delaying, slowing, or preventing

More information

WORKING TOGETHER TO MANAGE DIABETES

WORKING TOGETHER TO MANAGE DIABETES WORKING TOGETHER TO MANAGE DIABETES DIABETES MEDICATIONS SUPPLEMENT SECTION A DIABETES MEDICATIONS Agent Class Primary Action Typical Dosage Side Effects Tolbutamide (Ornase TM ) Tolazamide (Tolinase TM

More information

New medicines for type 2 diabetes when do you use them

New medicines for type 2 diabetes when do you use them New medicines for type 2 diabetes when do you use them 1. Oral Secretagogues (e.g. sulfonylureas) 2. Metformin 3. Alpha glucosidase inhibitors 4. Thiazolidinediones 5. GLP-1 receptor agonists 6. DPP-4

More information

UVA OUTPATIENT SURGERY CENTER (OPSC) PREPARING FOR SURGERY HANDBOOK

UVA OUTPATIENT SURGERY CENTER (OPSC) PREPARING FOR SURGERY HANDBOOK Surgeon Name/PIC: Surgery Name: Surgery Date: Patient Label or Patient NAME Patient UVA MRN ARRIVAL TIME: (provided by OPSC nurse during phone call) UVA OUTPATIENT SURGERY CENTER (OPSC) PREPARING FOR SURGERY

More information

Disclosure. Outline of today s talk 4/11/2016. Diabetic Complications

Disclosure. Outline of today s talk 4/11/2016. Diabetic Complications Disclosure Participation as a speaker for Astra-Zeneca, Sanofi- Aventis, and Janssen Pharmaceuticals Richard S. Crawford, MD Avera Medical Group Endocrinology and Diabetes April 15, 2016 Outline of today

More information

Leicestershire Diabetes Guidelines: Insulin Therapy

Leicestershire Diabetes Guidelines: Insulin Therapy Endorsed by Leicestershire Medicines Strategy Group Leicestershire Diabetes Guidelines: Insulin Therapy These guidelines are designed for use by those trained and competent in insulin initiation and management

More information

A patient s guide to the. management of diabetes at the time of surgery

A patient s guide to the. management of diabetes at the time of surgery A patient s guide to the management of diabetes at the time of surgery Diabetes is a common condition, affecting at least 4 to 5% of people in the UK. At least 10% of patients undergoing surgery have diabetes.

More information

Pharmaceutical Management of Diabetes Mellitus

Pharmaceutical Management of Diabetes Mellitus 1 Pharmaceutical Management of Diabetes Mellitus Diabetes Mellitus (cont d) Signs and symptoms 2 Elevated fasting blood glucose (higher than 126 mg/dl) or a hemoglobin A1C (A1C) level greater than or equal

More information

2013 International Diabetes Center

2013 International Diabetes Center Day to Day Management of Diabetes Part 1 Review of Diabetes and Therapies Diane Reader RD, CDE Manager, Diabetes Professional Training International Diabetes Center Overview of Diabetes lucose and Insulin

More information

Initiation and Adjustment of Insulin Regimens for Type 2 Diabetes

Initiation and Adjustment of Insulin Regimens for Type 2 Diabetes PL Detail-Document #300128 This Detail-Document accompanies the related article published in PHARMACIST S LETTER / PRESCRIBER S LETTER January 2014 Initiation and Adjustment of Insulin Regimens for Type

More information

Premixed Insulin for Type 2 Diabetes. a gu i d e f o r a d u lt s

Premixed Insulin for Type 2 Diabetes. a gu i d e f o r a d u lt s Premixed Insulin for Type 2 Diabetes a gu i d e f o r a d u lt s March 2009 What This Guide Covers / 2 Type 2 Diabetes / 3 Learning About Blood Sugar / 4 Learning About Insulin / 5 Comparing Medicines

More information

Prescribing for Diabetes, England 2005-06 to 2012-13

Prescribing for Diabetes, England 2005-06 to 2012-13 Prescribing for Diabetes, England 2005-06 to 2012-13 Published 13 August 2013 This product is relevant to members of the public and other stakeholders to support the understanding of primary care prescribing

More information

Presented By: Dr. Nadira Husein

Presented By: Dr. Nadira Husein Presented By: Dr. Nadira Husein I have no conflict of interest Disclosures I have received honoraria/educational grants from the following: Novo Nordisk, Eli Lilly, sanofi-aventis, Novartis, Astra Zeneca,

More information

Oral Therapy for Type 2 Diabetes

Oral Therapy for Type 2 Diabetes Oral Therapy for Type 2 Diabetes Diabetes pills can help to manage your blood sugar. These pills are not insulin. They work to manage your blood sugar in several ways. You may be given a combination of

More information

Diabetes Mellitus. Diabetes Mellitus. DR. JOHN O BRYAN Email: obryanj@uic.edu 4091 COMRB

Diabetes Mellitus. Diabetes Mellitus. DR. JOHN O BRYAN Email: obryanj@uic.edu 4091 COMRB INSULIN AND ORAL HYPOGLYCEMICS Rang, Chapter 15 pp380-393 Katzung, Chapter 41 pp693-711 additional reference: Goodman and Gilman The Pharmacological Basis of Therapeutics DR. JOHN O BRYAN Email: obryanj@uic.edu

More information

Management of Diabetes in the CKD Patient

Management of Diabetes in the CKD Patient Management of Diabetes in the CKD Patient Heather Naylor, BScPharm, ACPR Clinical Pharmacy Practice Leader, Nephrology Saint John Regional Hospital Horizon Health Network, Zone 2 May 26, 2012 Learning

More information

Your Guide to Diabetes Medications

Your Guide to Diabetes Medications Your Guide to Diabetes Medications A supplement to Diabetes Dialogue, an official publication of the Canadian Diabetes Association Spring 2007 Your diabetes meds at work Know your diabetes ABCs Pharmacists

More information

Prior Authorization Guideline

Prior Authorization Guideline Prior Authorization Guideline Guideline: PC (CO) - Insulin Delivery Systems Therapeutic Class: Hormones and Synthetic Substitutes Therapeutic Sub-Class: Insulin Delivery Systems Client: CO Approval Date:

More information

Cardiac Rehabilitation New Brunswick: Tutorial Series. Diabetes Mellitus Overview, pharmacotherapy and exercise considerations

Cardiac Rehabilitation New Brunswick: Tutorial Series. Diabetes Mellitus Overview, pharmacotherapy and exercise considerations Cardiac Rehabilitation New Brunswick: Tutorial Series Diabetes Mellitus Overview, pharmacotherapy and exercise considerations Overview Prevalence of diabetes Definition and Diagnosis Risk factors and complications

More information

81 Central Street, Houghton Estate, 2198 PO Box 2900, Saxonwold, 2132 www.cdediabetes.co.za

81 Central Street, Houghton Estate, 2198 PO Box 2900, Saxonwold, 2132 www.cdediabetes.co.za 81 Central Street, Houghton Estate, 2198 PO Box 2900, Saxonwold, 2132 www.cdediabetes.co.za Clinical Guidelines 2015 The Use of Antibody Testing in the Management of Diabetes Mellitus When should the Antibody

More information

Type 2 Diabetes. Aims and Objectives. What did you consider? Case Study One: Miss S. Which to choose?!?! Modes of Action

Type 2 Diabetes. Aims and Objectives. What did you consider? Case Study One: Miss S. Which to choose?!?! Modes of Action Aims and Objectives This session will outline the increasing complexities of diabetes care, and the factors that differentiate the combinations of therapy, allowing individualisation of diabetes treatment.

More information

Diabetes: Medications

Diabetes: Medications Diabetes: Medications Presented by: APS Healthcare Southwestern PA Health Care Quality Unit (APS HCQU) May 2008 sh Disclaimer Information or education provided by the HCQU is not intended to replace medical

More information

DIABETES MEDICATION-ORAL AGENTS AND OTHER HYPOGLYCEMIC AGENTS

DIABETES MEDICATION-ORAL AGENTS AND OTHER HYPOGLYCEMIC AGENTS Section Two DIABETES MEDICATION-ORAL AGENTS AND OTHER HYPOGLYCEMIC AGENTS This section will: Describe oral agents (pills) are specific for treating type 2 diabetes. Describe other hypoglycemic agents used

More information

SHORT CLINICAL GUIDELINE SCOPE

SHORT CLINICAL GUIDELINE SCOPE NATIONAL INSTITUTE FOR HEALTH AND CLINICAL EXCELLENCE SHORT CLINICAL GUIDELINE SCOPE 1 Guideline title Type 2 diabetes: newer agents for blood glucose control in type 2 diabetes 1.1 Short title Type 2

More information

Diabetes Mellitus 1. Chapter 43. Diabetes Mellitus, Self-Assessment Questions

Diabetes Mellitus 1. Chapter 43. Diabetes Mellitus, Self-Assessment Questions Diabetes Mellitus 1 Chapter 43. Diabetes Mellitus, Self-Assessment Questions 1. A 46-year-old man presents for his annual physical. He states that he has been going to the bathroom more frequently than

More information

Diabetes DIABETES MELLITUS. Types of Diabetes. Classification of Diabetes 6. 10. 2013. Prediabetes: IFG, IGT, Increased A1C

Diabetes DIABETES MELLITUS. Types of Diabetes. Classification of Diabetes 6. 10. 2013. Prediabetes: IFG, IGT, Increased A1C Diabetes Diabetes mellitus is a chronic disease characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both. A state of raised blood glucose (hyperglycaemia)

More information

TYPE2DIABETES INSULIN TREATMENT 2009 UPDATE ON A HEALTHCARE PROFESSIONAL S GUIDE TO TREATMENT BY J. ROBIN CONWAY, MD. www.diabetesclinic.

TYPE2DIABETES INSULIN TREATMENT 2009 UPDATE ON A HEALTHCARE PROFESSIONAL S GUIDE TO TREATMENT BY J. ROBIN CONWAY, MD. www.diabetesclinic. TYPE2DIABETES INSULIN TREATMENT 2009 UPDATE ON A HEALTHCARE PROFESSIONAL S GUIDE TO TREATMENT BY J. ROBIN CONWAY, MD www.diabetesclinic.ca Author: Dr. Robin Conway Note to readers The contents herein represent

More information

Britni Hebert, MD PGY-1

Britni Hebert, MD PGY-1 Britni Hebert, MD PGY-1 Importance of Diabetes treatment Types of treatment Comparison of treatment/article Review Summary Example cases 1 out of 13 Americans have diabetes Complications include blindness,

More information

Insulin T Y P E 1 T Y P E 2

Insulin T Y P E 1 T Y P E 2 T Y P E 1 T Y P E 2 INSULIN There are many different insulins for many different situations and lifestyles. This section should help you and your doctor decide which insulin or insulins are best for you.

More information

A Personalized Approach for A1C Goals

A Personalized Approach for A1C Goals PL Detail-Document #280708 This PL Detail-Document gives subscribers additional insight related to the Recommendations published in PHARMACIST S LETTER / PRESCRIBER S LETTER July 2012 A Personalized Approach

More information

SUBJECT: DIABETES MEDICATION MANAGEMENT PROTOCOLS

SUBJECT: DIABETES MEDICATION MANAGEMENT PROTOCOLS SUBJECT: DIABETES MEDICATION MANAGEMENT PROTOCOLS PURPOSE To establish a process that will enable Certified Diabetes Educators (CDE) and/or staff with Board Certification in Advanced Diabetes Management

More information

Prescribing for Diabetes. England 2005-06 to 2013-14

Prescribing for Diabetes. England 2005-06 to 2013-14 Prescribing for Diabetes England 2005-06 to 2013-14 Published 12 August 2014 We are the trusted national provider of high-quality information, data and IT systems for health and social care. www.hscic.gov.uk

More information

Insulin pen start checklist

Insulin pen start checklist Insulin pen start checklist Topic Instruction Date & Initials 1. Cognitive Assessment 2. Insulin Delivery loading appropriate mixing priming shot dialing up dose delivery of insulin 3. Insulin type/action

More information

CLASS OBJECTIVES. Describe the history of insulin discovery List types of insulin Define indications and dosages Review case studies

CLASS OBJECTIVES. Describe the history of insulin discovery List types of insulin Define indications and dosages Review case studies Insulins CLASS OBJECTIVES Describe the history of insulin discovery List types of insulin Define indications and dosages Review case studies INVENTION OF INSULIN 1921 The first stills used to make insulin

More information

Global Diabetes Market Trends & Future Forecast Diabetes Drug (Anti-Diabetic Drug), Insulin, DPP-IV, GLP-

Global Diabetes Market Trends & Future Forecast Diabetes Drug (Anti-Diabetic Drug), Insulin, DPP-IV, GLP- Brochure More information from http://www.researchandmarkets.com/reports/1241622/ Global Diabetes Market Trends & Future Forecast Diabetes Drug (Anti- Diabetic Drug), Insulin, DPP-IV, GLP-1 Description:

More information

Intensifying Insulin Therapy

Intensifying Insulin Therapy Intensifying Insulin Therapy Rick Hess, PharmD, CDE, BC-ADM Associate Professor Gatton College of Pharmacy, Department of Pharmacy Practice East Tennessee State University Johnson City, Tennessee Learning

More information

25 mg QD-TID @ meals w/1st bite of. food, titrate Q 4 8 weeks; adjust based on 1 postprandial glucose; 100 mg TID max

25 mg QD-TID @ meals w/1st bite of. food, titrate Q 4 8 weeks; adjust based on 1 postprandial glucose; 100 mg TID max Table Selected Non-Insulin Antihyperglycemic Agents Class Drug (Brand) Dosing Comments -Glucosidase inhibitors Acarbose a (Precose) 25 mg QD-TID @ meals w/1st bite of MOA: Enzyme inhibitor, delays hydrolysis

More information

Medication Review. What is Diabetes? Medications. Michelle Weddell. Business Development Executive Clinical Specialist Podiatrist

Medication Review. What is Diabetes? Medications. Michelle Weddell. Business Development Executive Clinical Specialist Podiatrist Medication Review Michelle Weddell Business Development Executive Clinical Specialist Podiatrist What is Diabetes? What is a type 1 diabetic? What is type 2 diabetic? Is there other forms of diabetes?

More information

New Drugs in the Management of Type 2 Diabetes. Daniel K. Short MD, PhD, FACP, FACE

New Drugs in the Management of Type 2 Diabetes. Daniel K. Short MD, PhD, FACP, FACE New Drugs in the Management of Type 2 Diabetes Daniel K. Short MD, PhD, FACP, FACE Disclosure I am or have been on the speaker s bureaus for multiple pharmaceutical companies: Abbvie Astra-Zeneca Boehringer

More information