THICKER GEL GENERATES MORE IODINE
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- Francine Briggs
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1 THICKER GEL GENERATES MORE IODINE Hydrogen peroxide More Iodide Thicker Gel Oxygen More Iodine
2 IODOZYME HAS SIGNIFICANTLY LOWER IODINE LEVELS THAN CONVENTIONAL IODINE DRESSINGS Free iodine (I -& I ) concentration/ µm Inadine Iodoflex Time / h Inadine and Iodoflex are registered trademarks. No attempt is made to supersede these or any other trademarks
3 IODOZYME STILL PRODUCES OXYGEN % dissolved oxygen concentration with respect to air saturated solution at C Hypoxia Peak Oxygenation Triggers signals to kick-start healing Metabolic support for cells Enhanced leucocyte respiratory burst To support both growth and function of keratinocytes Time (Hours) To support both growth and function of fibroblasts Control Declining Oxygenation In vitro data, on file at Insense Ltd.
4 WHEN TO USE OXYZYME and IODOZYME Continuum of infection Defence against infection Contamination (Managed by the body s natural defenses) Colonisation (established microbial population, body in control, microbial balance) Body s natural resistance Critical Colonisation (established microbial population, wound not progressing, microbial imbalance, no signs of infection) Topical antiseptic agents Infection (microbial control) Topical antiseptic agents Systemic antibiotics
5 WHEN TO USE OXYZYME and IODOZYME Continuum of infection Defence against infection Contamination (Managed by the body s natural defenses) Colonisation (established microbial population, body in control, microbial balance) Body s natural resistance Critical Colonisation (established microbial population, wound not progressing, microbial imbalance, no signs of infection) Topical antiseptic agents Infection (microbial control) Topical antiseptic agents Systemic antibiotics
6 WHEN TO USE OXYZYME and IODOZYME Continuum of infection Defence against infection Contamination (Managed by the body s natural defenses) Colonisation (established microbial population, body in control, microbial balance) Body s natural resistance Critical Colonisation (established microbial population, wound not progressing, microbial imbalance, no signs of infection) Supporting natural resistance Topical antiseptic agents Infection (microbial control) Topical antiseptic agents Systemic antibiotics
7 IODINE VS. SILVER Iodine is well known to be a stronger antimicrobial than silver IODOZYME is effective, despite the lower level of iodine because it supports the bodies natural defences
8 Comparison of Antimicrobial effectiveness # In vitro diffusion bed, -day repeat challenge capacity test for antimicrobial wound dressings.,, Greenman J, Thorn RMS, Saad S, Austin A. J. International Wound Journal, ;: 9. Methicillin- Resistant Staphylococcus aureus (MRSA) Pseudomonas aeruginosa Wound dressing Iodozyme (Archimed) Silvercel Hydro- Alginate (Johnson & Johnson) Contreet (Coloplast) Acticoat Absorbent (Smith & Nephew) Antimicrobial agent Iodine Silver Silver Silver ( nanocrystalline ) Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
9 Vergelijking IODOZYME versus zilverdressings: MRSA Dag. Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht. Log CFU/ cm.... Silvercel Contreet.. Acticoat. Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
10 Vergelijking IODOZYME versus zilverdressings: MRSA Dag. Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht. Log CFU/ cm.... Silvercel Contreet Acticoat... Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
11 Vergelijking IODOZYME versus zilverdressings: MRSA Dag. Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht Log CFU/ cm..... Silvercel Acticoat Contreet... Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
12 Vergelijking IODOZYME versus zilverdressings: Pseudomonas Dag 9 Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht Log CFU/ cm Acticoat Silvercel Contreet Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
13 Vergelijking IODOZYME versus zilverdressings: Pseudomonas Dag 9 Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht Log CFU/ cm Silvercel Acticoat Contreet Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
14 Vergelijking IODOZYME versus zilverdressings: Pseudomonas Dag 9 Dagen, waarbij iedere dag een nieuwe gelijke hoeveelheid bacterieen op dezelfde dressing is aangebracht Silvercel Log CFU/ cm Contreet Acticoat Silvercel, Contreet and Acticoat are registered trademarks. No attempt is made to supersede these or any other trademarks
15 Comparison of Antimicrobial effectiveness # Greenman J, Thorn RMS, Saad S, Austin A. J. (not yet published) Methicillin-Resistant Staphylococcus aureus (MRSA) Pseudomonas aeruginosa Wound dressing Iodozyme (Archimed) Aquacel Ag (Convatec) Antimicrobial agent Iodine Silver Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
16 Vergelijk IODOZYME vs Aquacel Ag: MRSA Dag Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
17 Vergelijk IODOZYME vs Aquacel Ag: MRSA Dag Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
18 Vergelijk IODOZYME vs Aquacel Ag: MRSA Dag Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
19 Vergelijk IODOZYME vs Aquacel Ag: Pseudemonas Dag 9 Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
20 Vergelijk IODOZYME vs Aquacel Ag: Pseudemonas Dag 9 Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
21 Vergelijk IODOZYME vs Aquacel Ag: Pseudemonas Dag 9 Aquacel Log CFU/ cm Aquacel is a registered trademark. No attempt is made to supersede this or any other trademarks
22 SUMMARY OF IODOZYME CLINICAL TRIAL Deteriorated % Healed % Static % Improved %
23 IODOZYME SUMMARY IODOZYME uses the same technology as OXYZYME but generates a higher, antimicrobial level of iodine IODOZYME still generates oxygen and so still addresses the issue of oxygen balance in the wound and supports the bodies natural defences The level of iodine produced by IODOZYME is significantly lower than that of conventional iodine dressings The in-vitro antimicrobial activity of IODOZYME has been shown to be effective, even against Pseudomonas and MRSA
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