CURRICULUM VITAE. School of Nursing, UTMB. Peking University, Beijing, China. Shandong Medical University, Shandong, China

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1 PRESENT POSITION AND ADDRESS: Nurse Practitioner Department of Neurology University of Texas Medical Branch 301 University Blvd., Galveston, TX CURRICULUM VITAE BIOGRAPHICAL: Citizenship; USA Business Address: same as above Telephone; Home Address and Telephone: Rocky Oak CT, Houston, TX 77059; Education: Jan Dec : Sep July 2001: Sep July 1995: Sep July 1989: MSN, Acute Care Nurse Practitioner program School of Nursing, UTMB Ph.D. (Neuroscience) Peking University, Beijing, China Master degree of Medicine (Physiology) Medical School, Qingdao University, Qingdao, China Bachelor Degree of Medicine Shandong Medical University, Shandong, China BOARD CERTIFICATION Acute Care Nurse Practitioner certification, American Nurses Credentialing Center Certified Medical-Surgical RN, American Nurses Credentialing Center LICENSURE INFORMATION Acute care nurse practitioner, Texas Board of Nursing Registered Nurse, Texas Board of Nursing PROFESSIONAL AND TEACHING EXPERIENCE 8/2012-6/2014: Nurse practitioner, internal medicine, hospitalist group, Bayshore Medical Center, Pasadena, TX 5/ /2012: Nurse practitioner, internal medicine clinic, Mainland Primary Care Physicians, Texas City, TX 1/2008-8/2012: Registered nurse, Nurse Clinician IV, ACE unit, UTMB, Galveston, TX 4/2002-1/2008: Research investigator, Department of Neuroscience & Cell Biology, UTMB 7/1995-3/2002: Assistant professor, Department of pathophysiology Medical School, Qingdao University, China 7/1989-7/1995: Advanced practice nurse, cardiology, Qingdao Municipal Hospital, Qingdao, China. RESEARCH ACTIVITIES Area of Research: pain and central sensitization, acupuncture and pain modulation

2 Grant Support Past Source: NS (United States NINDS NIH HHS) Title: Peripheral and central sensitization PI: Dr. William Willis Time Period: Total Cost: $ 2,000,000 Source: NS (United States NINDS NIH HHS) Title: Pain and inflammation PI: Dr. William Willis Time Period: Total Cost: 1,600,000 Source: DA03983 (United States NIDA NIH HHS) Title: The effect of acupuncture in drug abuse and pain modulation PI: Dr. Jishen Han Time Period: Total Cost: $250,000 MEMBERSHIP IN SCIENTIFIC SOCIEY/PROFESSION ORGANIZATION Galveston Coalition of Advanced Practice Nurses (2010-current) Society for Neuroscience ( ) American Pain Society* ( ) HONORS 2010 National Science and Technology Award (Second place) from Chinese Association for the Study of Acupuncture for neurobiological mechanism of acupuncture analgesia 2004 Young Investigator Travel Award from American Pain Society 2006 Young Investigator Travel Award from American Pain Society 2007 Young Investigator Travel Award from American Pain Society ADDITIONAL INFORMATION Journal Reviewer for Brain Research, Chinese Journal of Pain Medicine, Reviewer for Acta Academiae Medicinae Qingdao , Brain Research , Chinese Journal of Pain Medicine , Acta Academiae Medicinae Qingdao Students/Trainees: MD student: Wei Guo, Zheng Jing, PhD student: Jingyin Yan,

3 Community service: , President, Huaxia Chinese School at Galveston PUBLISHED A. ARTICLES IN PEER-REVIEWED JOURNALS: 1. Sun RQ, Yan JY, Willis WD (2007).Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin. Neuroscience, 144(1): Sun RQ, Tu YJ, Yan JY, Willis WD (2006). Activation of protein kinase B/Akt signaling pathway contributes to mechanical hypersensitivity induced by capsaicin. Pain, 120(1-2): Yan JY, Sun RQ, Hughes MG, McAdoo D J, Willis WD (2006). Intradermal injection of capsaicin induces acute SP release from rat spinal cord dorsal horn. Neurosci Lett, 410(3): Sun RQ, Tu YJ, Lawand NB, Yan JY, Lin Q, Willis WD (2004). Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. Journal of Neurophysiology, 92(5): Sun RQ, Lawand NB, Lin Q, Willis WD (2004). Role of calcitonin gene-related peptide in the sensitization of dorsal horn neurons to mechanical stimulation after intradermal injection of capsaicin. Journal of Neurophysiology. 92(1): Tu Y, Sun RQ, Willis WD. Effects of intrathecal injections of melatonin analogs on capsaicininduced secondary mechanical allodynia and hyperalgesia in rats (2004). Pain. 109(3): Sun RQ, Wang HC, Wan Y, Jing Z, Luo F, Han JS, Wang Y (2004). Suppression of neuropathic pain by peripheral electrical stimulation in rats: mu-opioid receptor and NMDA receptor implicated. Experimental Neurology, 187(1): Sun RQ, Lawand NB., Willis WD (2003). The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. Pain, 104: Sun RQ, Zhao CS, Wang HJ, Jing Z, Wang W, Yang K, Wang Y, Chang JK, and Han JS (2001). Nocistatin, a peptide reversing acute and chronic morphine tolerance. NeuroReport, 12 (8): Sun RQ, Wang Y, Zhao CS, Chang JK, and Han JS (2001).Changes in brain content of nociceptin/orphanin FQ and endomorphin 2 in a rat model of neuropathic pain. Neurosci Lett, 311: Zhao CS, Sun RQ, Li BS, Wang Y, Luo F, Wang XM, Chang JK, and Han JS. Effect of nocistatin in pain modulation. Chinese Science Bulletin, 1999, 44 (22): (Chinese edition); 2000, 45 (8): (English edition) 12. Sun RQ, Wang HC, Wang Y, Luo F, and Han JS (2002). Effect of electroacupuncture with different frenquencies on neuropathic pain in a rat model. Chinese J Appl Physiology, 18 (2): Sun RQ, Wang HC, Jing Z, WangY, Wan Y and Han JS (2004). The inhibition of neuropathic pain by electroacupuncture is differential dependent on endogenous opioid systerm and nonopioid systerm. Chinese Journal of Pain Medicine. 14. Sun RQ, Wang Y, Wan Y, Han JS (2004). The mechanism of neuropathic pain (review). Chinese J Pain Medicine. 15. Sun RQ, Wang SQ, Tao SM and Chen JJ (1999). The relationship between dopamine and the effect of central neurotensin on gastric stress ulcers in rats. Chinese J Pathophysiology,

4 15(4): Sun RQ, Liu H, Yuan CH, Wang YZ and Chen JJ (1997). The cytoprotective effect of neurotensin on gastric mucosa and its relationship with prostaglandin in gastric mucosa. Acta Academiae Medicinae Qingdao, 33(4): Liang FB, Sun RQ, Chen L, Chen WF, Chen JJ (1997). The effect of intracerebroventricular injection of beta-indorphin on the level of sialic acid in plasma. Acta Academiae Medicinae Qingdao, 33(4): Sun RQ, Chen JJ and Yuan CH (1996). The cytoprotective effect of neurotensin in central amygdale on gastric stress ulcer. Acta Academiae Medicinae Qingdao. 32(3): Wang SQ, Sun RQ (1996). Clinic analysis about 21 cases of hepatic hydrothorax. Acta Academiae Medicinae Qingdao, 32 (1): Wang SQ, Sun RQ (1996). The relationship between e antigen-antibody system and hepatocirrhosis. Hebei Medicine, 18 (6): 343. B. ABSTRACTS 1. Sun RQ, Yan JY, Willis WD (2007). The signaling pathway of CGRP 1 receptor activation. Soc Neurosci Abstr, Sun RQ, Yan JY, Willis WD (2007). Protein kinase B/Akt participates in the sensitization of wide dynamic dorsal horn neuron induced by capsaicin. American Pain Society s 26th Annual Scientific meeting. 3. Yan JY, Sun RQ, Willis WD (2007). American Pain Society s 26th Annual Scientific meeting. 4. Sun RQ, Yan JY, Willis WD (2006).CGRP 1 receptor contributes to CaMKII activation and camp response element-binding protein phosphorylation in the spinal cord induced by intradermal injection of capsaicin. Soc Neurosci Abstr, Yan JY, Sun RQ, Willis WD (2006). CaMKII activation in rat dorsal horn tissues following spinal cord SP treatment. Soc Neurosci Abstr, Sun RQ, Yan JY, Willis WD (2006). Protein Kinase B in the periphery is involved in pain behavior. American Pain Society s 25th Annual Scientific meeting. 7. Yan JY, Sun RQ, Yan JY, Willis WD (2006). Spinal NK-1 receptor contributes to capsaicin-induced secondary mechanical allodynia and hyperalgesia. American Pain Society s 25th Annual Scientific meeting. 8. Sun RQ, Tu YJ, Yan JY, Willis WD (2005).Activation of protein kinase B/Akt in primary afferent neurons and skin by noxious stimulation and its contribution to inflammatory mechanical hyperalgesia. Soc Neurosci Abstr, Yan JY, Sun RQ, Willis WD (2005). Effects of CaMK II, PKA and PKC in substance P- induced sensitization of wide-dynamic-range neurons. Soc Neurosci Abstr, Sun RQ, Tu YJ, Willis WD (2005).Activation of the phosphoinositide 3-kinase-Akt/PKB signaling pathway in primary sensory neurons after peripheral peripheral inflammation contributes to inflammatory mechanical hyperalgesia. The Journal of Pain, 6 (3):S Tu YJ, Sun RQ, Willis WD (2005).Peripheral inhibitory effects of protein kinase B (Akt) inhibitors on capsaicin-induced secondary mechanical allodynia and hyperalgesia in awake rats. The Journal of Pain, 6 (3):S Yan JY, Sun RQ, Nie, L.H, Hughes, M., Dunsmore, J., McAdoo, D., and Willis, W.D. (2005). Substance P contributes to spinal cord central sensitization induced by capsaicin. The Journal of Pain, 6 (3):S Sun RQ, Tu YJ, Willis WD (2005). PKB/Akt signaling pathway in primary sensory

5 neurons is required for inflammatory mechanical hyperalgesia. 11th World Congress on Pain, # Sun RQ, Tu YJ, Zou XJ, Willis WD (2004). Activation of protein kinase B/Akt signaling pathway contributes to spinal cord central sensitization. Soc Neurosci Abstr, Tu YJ, Sun RQ, Willis WD (2004). PKB/Akt mediates the effect of NGF and BDNF on mechanical hyperalgesia in spinal cord of rats. Soc Neurosci Abstr, Sun RQ, Tu YJ, Lawand NB, Lin Q, Willis WD (2004). CGRP receptor activation produces PKA and PKC dependent mechanical hyperalgesia and central sensitization. The Journal of Pain, 5 (3): Tu YJ, Sun RQ, Willis WD (2004). Effects of intrathecal injection of protein kinase B inhibitor on capsaicin- induced secondary mechanical allodynia and hyperalgesia in rats. The Journal of Pain, 5 (3): Sun RQ, Lawand NB, Lin Q, Willis WD (2003). Capsaicin-induced sensitization of dorsal horn neurons is prevented or reversed by CGRP 8-37, a specific CGRP 1 receptor antagonist. Soc Neurosci Abstr, Sun RQ, Lawand NB, Willis WD (2003). The role of calcitonin gene-related peptide (CGRP) and its receptor in central sensitization. The Journal of Pain, 4(2): Sun RQ, ZhaoCS, Wang HJ, Wang W, Yang K, Wang Y, Chang JK, and Han JS (2000). Nocistatin reverses morphine tolerance. Chinese Journal of Pain Medicine. Proceedings of the 2000 East-West Pain Conference, 6(1s):61.