CURRICULUM VITAE. Axel R. Pries. Professor of Physiology. February 20, 1954 in Cologne

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1 CURRICULUM VITAE NAME: DEGREE: BIRTHDATE: OFFICE: Axel R. Pries Professor of Physiology February 20, 1954 in Cologne Charité - Universitätsmedizin Berlin, Dept. of Physiology-CBF, Arnimallee 22, Berlin, Germany tel: /32, fax: EDUCATION: 1972 Final examination (Abitur), Friedrich-Wilhelm-Gymnasium, Köln Studies of Medicine, University of Cologne 1979 Final medical examination (Staatsexamen) 12/1979 Licence to practise as a physician (Approbation) 2/1980 Doctoral degree (Dr. med.), University of Cologne 7/1990 Habilitation in Physiology, Medical Faculty, Freie Universität Berlin 9/1997 Specialist in Physiology (Facharzt für Physiologie), Ärztekammer Berlin PROFESSIONAL EMPLOYMENT: Postdoctoral Fellow, Institute of Normal and Pathological Physiology, University of Köln Postdoctoral Fellow, Department of Physiology, Freie Universität Berlin 1985 Research Assistant (C1), Department of Physiology, Freie Universität Berlin 1991 Lecturer of Physiology (C2), Department of Physiology, Freie Universität Berlin 1995 Associate Professor, Department of Physiology, Freie Universität Berlin Institute of Anesthesiology, Deutsches Herzzentrum Berlin (German Heart Center Berlin) 12/1998 Full Professor (C3), Department of Physiology, Freie Universität Berlin 10/1999-2/2001 Vice Director, Department of Physiology, Freie Universität Berlin 10/1999-present Acting Head, Vegetative Physiology Section, Department of Physiology, Freie Universität Berlin 2/2001-present Head, Department of Physiology-CBF, Charité-Berlin since 12/2003 Board Member of the Faculty of Medicine, Charité-Berlin ACADEMIC TEACHING EXPERIENCE: Physiology; lectures, lab courses, seminars, examinations, educational training Pathophysiology; lectures Medical physics; educational training Organ Perfusion and ; coaching Bioinformatics; Bachelor and Master Programme, Organisation of physiological curriculum, teaching RESEARCH INTERESTS: Blood rheology*

2 Vascular adaptation* Angiogenesis* Ischemia/Reperfusion Endothelial surfaces* *(experiments and mathematical model simulations) HONORS AND AWARDS: 1980 Thesis Award, Hochhausstiftung, Medical Faculty, University of Cologne 1986 Abbott Award, European Society for : K. Ley, A.R. Pries, P. Gaehtgens: "Topological structure of rat mesenteric microvessel networks" Microvasc. Res. 32: (1986) 1992 Best Poster Award, European Association of Cardiothoracic Anaesthesiologists: B. Lamparter, A. Pries, J.-H. Baumert, M. Adt, P. Gaehtgens: "Potentiation of microvascular contraction after norepinephrine application caused by impaired endothelial function in rat mesenteric arteries" 7th Annual Meeting der EACTA '92 in Maastricht, Holland 1995 International Society for Clinical Haemorheology and Laboratoire L. Lafon Hemorheology- Award: A.R. Pries, T.W. Secomb, T. Gessner, M.B. Sperandio, J.F. Gross, P. Gaehtgens: "Resistance to blood flow in microvessels in vivo." Circ. Res. 75: (1994) 2000 Fellow of the European Society of Cardiology SOCIETY MEMBERSHIP AND OFFICES HELD: - American Physiological Society (APS) - The Microcirculatory Society, Inc., USA (MCS) - European Society of Cardiology (ESC) Working Group on Coronary Pathophysiology and Nucleus, Vice Chairman, Chairman, Executive Secretary & Past Chair, Executive Secretary, Advisory Board, 2003-present Council on Basic Cardiovascular Sience, Nucleus, 2004-present - European Society for (ESM) Member of Executive, 1995-present Member of Development Group, General Secretary, 1998-present - International Union of Physiological Societies (IUPS) Commission on and Capillary Transport resp. since 2004: Physiome and Bioengineering - Deutsche Physiologische Gesellschaft e.v. (German Physiological Society) - Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.v. (German Society for and Vascular Biology) Member of Executive Board, nd Vice-Chair, 1994 Chairman, organisation and host of annual meeting, 1995 European Society for Delegate, General Secretary, 1996-present - Deutsche Gesellschaft für Kardiologie (German Society for Cardiology) - Deutsche Gesellschaft für Klinische Mikrozirkulation und Hämorheologie (German Society for Clinical and Hemorheology)

3 EDITORIAL BOARDS: Journal of Vascular Research Pflügers Archiv European Journal of Physiology Bulletin of the Portuguese Society of Hemorheology and REFEREE for ORGANIZATIONS: Deutsche Forschungsgemeinschaft (DFG) European Space Agency (ESA) NATO Collaborative Research Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung The Wellcome Trust REFEREE for JOURNALS: American Journal of Physiology Anesthesiology Annals of Biomedical Engineering Basic Research in Cardiology Biophysical Journal Biorheology Cardiovascular Research Circulation Research Clinical and Experimental Hypertension European Surgical Research Infusionstherapie und Transfusionsmedizin International Journal of : Clinical and Experimental International Journal of Sports Medicine Journal of Anatomy Journal of Applied Physiology and Occupational Physiology Journal of Biomedical Engineering Journal of Fluid Mechanics Journal of Molecular and Cellular Cardiology Journal of Physiology (London) Journal of Vascular Research Pflügers Archiv European Journal of Physiology Phlebologie Science ORGANIZATION: Conferences (scientific program and local organization): 2005 Minisymposium "Mechanismen und Pathomechanismen der vaskulären Regulation" (Mechanisms and Pathomechanisms of Vascular Regulation) of Forschergruppe 341, Berlin (together with M. Paul, Forschungsinstitut für Molekulare Pharmakologie, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin) rd European Conference on, Lisbon; External co-organization and Executive Programme

4 2000 Minisymposium "Mechanismen und Pathomechanismen der vaskulären Regulation" (Mechanisms and Pathomechanisms of Vascular Regulation) of Forschergruppe 341, Berlin (together with M. Paul, Forschungsinstitut für Molekulare Pharmakologie, Universitätsklinikum Benjamin Franklin der FU Berlin) 1997 First International Scientific Meeting of the Working Group on of the European Society of Cardiology, Berlin (together with H. Kuppe, Deutsches Herzzentrum Berlin) Jahrestagung der Gesellschaft für Mikrozirkulation e.v. (together with 14. Jahrestagung der Deutschen Gesellschaft für Klinische Mikrozirkulation und Hämorheologie), Berlin Symposia (scientific program): 29 since 1996 Scientific s: th European Conference on, Budapest; International Advisory Board th Congress of the European Society of Cardiology, Vienna; Congress Programme 2006 World Congress of Cardiology & 28th Congress of the European Society of Cardiology, Barcelona; Congress Programme th European Conference on, Amsterdam; Executive Programme th Congress of the European Society of Cardiology, Stockholm; Congress Programme th Asian Congress for (ACM 05) for Human Life -from Basics to Clinics- in conjunction with 30th Annual Meeting of Japanese Society for (JSM 05), Tokyo; International Advisory Board 2004 Jahrestagung der Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.v., Berlin; Scientific th Conference of the European Society of Biomechanics (ESB), s-hertogenbosch, The Netherlands; Scientific 2002 Meeting of the Working Group on of the European Society of Cardiology, Lugano: International Faculty nd Meeting of the European Society for The and Vascular Biology, Exeter; Executive Programme 2001 Jahrestagung der Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.v., Frankfurt; Scientific 2001 XXIIIrd Congress of the European Society of Cardiology, Stockholm; Scientific 2001 International Symposium "Advances in Vascular Pathology 2001", Monte Carlo, Monaco; International Advisory Board 2000 Jahrestagung der Gesellschaft für Mikrozirkulation und Vaskuläre Biologie e.v., Mainz; Wissenschaftlicher Beirat 2000 XXIInd Congress of the European Society of Cardiology, Amsterdam; Scientific st European Conference on, Stockholm; Scientific th Asian Congress for, Bandung, Indonesien; International Advisor/Steering 1999 First European Meeting on Vascular Biology and Medicine, Nürnberg; Scientific rd International Symposium of the Working Group on of the European Society of Cardiology "Changing Concepts for the Coronary Circulation _ Perspectives beyond the Usual", München; Scientific th Franz-Volhard-Symposium, Berlin; Scientific th World Congress for, München; International Scientific 1996 Programme Jahrestagung der Gesellschaft für Mikrozirkulation e.v., München; scientific program

5 INTERNATIONAL SCIENTIFIC COOPERATION: S Dept. of Physiology, University of Arizona, Tucson, USA Prof. Dr. T.W. Secomb Subject: Experimental and theoretical analysis of rheology and hemodynamics of microvascular networks S Depts. of Pharmacology and Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands Prof. Dr. H.A.J. Struijker Boudier Dr. F. Le Noble S Dept. of Physiology, University of Birmingham, U.K. Prof. Dr. O. Hudlicka S Institut für Veterinärphysiologie, Universität Zürich, Schweiz Prof. Dr. M. Gassmann Subject: Angiogenesis, Angioadaptation S Division of Cardiology, Ospedale Silvestrini, Università degli Studi di Perugia, Perugia, Italy Prof. Dr. G. Ambrosio Subject: Ischemia/reperfusion in skeletal muscle S Cardiovascular Research Center, University of Virginia Health System, Charlottesville, USA Prof. Dr. K. Ley S Dept. of Biochemistry, Hebrew University, Hadassah Medical School, Jerusalem, Israel Prof. Dr. S. Yedgar S Dept. of Biomedical Engineering, Boston University, Boston, Massachusetts, USA Assoc. Prof. Dr. E.R. Damiano Subject: Endothelial surface PEER REVIEWED PUBLICATIONS: 123 since 1979 PRESENTATIONS AND ABSTRACTS: ~400 since 1981 INVITED LECTURES: 63 since 1980

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