Stem Cell Research: Adult or Somatic Stem Cells

Size: px
Start display at page:

Download "Stem Cell Research: Adult or Somatic Stem Cells"

Transcription

1 Chiang 1 Stem Cell Research: Adult or Somatic Stem Cells Abstract Kelly Chiang Cluster 7 Dr. LeFebvre 07/26/10 Over the past few decades, stem cells have been a controversial topic in the scientific field. Researchers have been studying the unique characteristics of all the different types of stem cells, and they hope to be able to use stem cells for treating a wide variety of diseases and disorders. This paper introduces the many types of stem cells that scientists are learning about. It includes the basic information about the main three types of stem cells and how they are used to treat patients. According to National Geographic, nine-year old Anthony Pululu was cured of sickle cell anemia by a bone-marrow transplant performed by Paris physician Francoise Bernaudin (Liposuction Fat). Bone marrow transplant is actually an old stem cell therapy which is one of the more favorable therapies using adult or somatic stem cells as opposed to therapies using the more controversial embryonic stem cells. Anthony Pululu s immune and blood systems were wiped out and replaced with healthy bone marrow stem cells, which quickly reproduce and repopulate the body. This medical research breakthrough of stem cells brings much hope to patients similar to Anthony Pululu. Stem cells have so much potential because they are unspecialized cells found in most multi-cellular organisms which have the capacity to self-renew and to differentiate further into more mature and specialized cells. These cells serve as an internal repair system in some tissues because they are able to divide unlimitedly and replenish other cells. There are three main types of stem cells that have succeeded in scientific research; these three types include embryonic, fat, and adult or somatic stem cells. Embryonic stem cells, as

2 Chiang 2 implied from the name, are derived from the inner cell mass of the blastocyst, an early-stage embryo that develops from eggs in a clinic (Stem Cell Basics). This type of stem cell is pluripotent, meaning that the cell has the potential to differentiate into the endoderm (interior stomach lining, the lungs), mesoderm (muscle, bone, blood), or ectoderm (epidermal tissues and nervous system). In addition to pluripotency, embryonic stem cells have the ability to duplicate indefinitely under defined conditions. These characteristics allow embryonic stem cells to be useful tools in further scientific investigation such as studies of embryogenesis. Like embryonic stem cells, fat stem cells have been very successful in scientific research. Only recently, scientists have discovered that stem cells can also be extracted from human fat tissue. These stem cells have the same abilities as embryonic stem cells except for the ability to differentiate into sperm or ova (Liposuction Fat). One benefit of using fat stem cells instead of embryonic stem cells is that fat stem cells are abundant, and can easily be extracted (Liposuction Fat). In addition, fat stem cells pose no ethical or political controversy unlike embryonic stem cells. According to Scientific American, these fat stem cells have the ability to treat everything from damaged heart tissue to Parkinson s disease. Also, MSNBC has reported that surgeons have used stem cells from fat to help repair skull damages in a 7-year old girl from Germany (Stem Cells from Fat). Surgeons mixed bits of the child s bone with stem cells, in hope of the cells forming into bone-building cells that would create additional bone. Like embryonic stem cells, fat stem cells are definitely a promising new technology and may have the ability to save billions of lives in the future. The last type of stem cells, or adult/somatic stem cells, are undifferentiated cells found among differentiated cells in a tissue or organ. According to the National Institutes of Health, adult stem exist in various organs and tissues including brain, bone marrow, peripheral blood,

3 Chiang 3 blood vessels, skeletal muscle, skin, teeth, heart, gut, liver, ovarian epithelium, and testis (What is a Stem Cell). Scientists often use the term somatic stem cell rather than adult stem cell, because somatic refers to cells of the body, which does not include the germ cells. Adult stem cells have two distinct characteristics, they can make identical copies of themselves for long periods of time, and they can give rise to mature cell types that have morphologies and specialized functions. In addition, studies and research has shown that adult stem cells live in small blood vessels, and they can be extracted from a patient to help repair diseased or damaged tissue. Adult stem cells are a natural solution, meaning that they naturally exist in our bodies, and they provide a natural repair mechanism for many tissues of our bodies. In other words, these stem cells are responsible for repairing and maintaining the tissue of the living organism in which they are found. They serve as a built-in repair system for the human body, replenishing other cells as long as a person is still alive. Their primary functions are to maintain homeostasis and to replace the cells that have died from injury or disease. Scientific interest in these stem cells have centered around their ability to self-renew indefinitely. These versatile adult stem cells are essentially unused or blank cells that have the ability to become another more differentiated cell type in the body such as a skin cell or nerve cell. Within the last 50 or so years, researchers have discovered that the bone marrow contains at least two kinds of adult stem cells. The first population of stem cells is called hematopoietic stem cells which forms all the types of blood cells in the body. These stem cells have the ability to differentiate to a variety of specialized cells, mobilize out of the bone marrow into the blood stream, and undergo apoptosis (programmed cell death). Hematopoietic stem cells are easier to obtain compared to adult stem cells from other tissues. As reported by the International Society for Stem Cell Research, HSCs can be either aspirated directly from the bone marrow or

4 Chiang 4 stimulated to move into the peripheral blood stream, where they can be easily collected. HSCs have been studied by scientists for many years, and they were the first stem cells to be used successfully in treatments and therapies. According to the International Society, HSCs have been used to treat blood cancers (ex: leukemia) and blood disorders for decades. Also, just recently, HSCs have been tested in the treatment for other diseases and disorders like cancer and coronary artery diseases. However, one negative aspect about HSC is that basic HSC research has been a difficult challenge because HSCs appear and behave exactly like white blood cells (What are Adult Stem Cells). This makes them difficult to identify by morphology, therefore, scientists still rely on cell surface proteins on white blood cells to differentiate between white blood cells and HSCs. Nevertheless, HSCs are rapidly advancing in the biomedical field and they may soon have the potential to save millions of lives. Along with hematopoietic stem cells, mesenchymal stem cells are slowly gaining potential as well. Mesenchymal stem cells are another population of stem cells that are also found in the bone marrow. However, MSCS can also be isolated from other tissues including cord blood, peripheral blood, fallopian tube, and fetal liver and lung (What are Adult Stem Cells). These multipotent stem cells can differentiate into a variety of stem cells. Cell types that MSCs have been shown to differentiate into in vitro or in vivo include a variety of beta-pancreatic islets cells. In the laboratory, this well-characterized population of stem cells can form a variety of cells such as fat cells, cartilage, bone, tendon, and ligaments, as well as muscle and skin cells (What are Adult Stem Cells). Mesenchymal stem cells can be obtained in quantities appropriate for clinical applications unlike most other human stem cells, therefore making them good candidates for use in tissue repair. Also, research has proved that when MSCs are transplanted systematically, they are able to migrate to sites of injury in animals, making these stem cells

5 Chiang 5 potentially ideal candidates for tissue engineering. As reported by the International Society for Stem Cell Research, another benefit of MSCs is that they can be preserved by freezing them and when thawed, they function normally. An important consideration about MSCs for human applications is that they can be extracted from a small bone marrow sample from a certain patient, expanded in culture, and then given back to the patient. Scientists are still learning about MSCs; however our knowledge about them is increasing every day. These stem cells may have a lot of potential in the future, as well as other stem cells. Stem cells are being used today to help people suffering from dozens of diseases and conditions. Adult stem cells are being applied to numerous diseases including brain, ovarian, breast, and testicular cancer, type 1 diabetes, Parkinson s disease, spinal cord injury, stroke damage, and many more (What is a Stem Cell?). Most importantly, adult stem cells have already been successfully used in human therapies for many years. New therapies using adult type stem cells are being developed all the time. Works Cited Roach, John. "Liposuction Fat Turned Into Stem Cells, Study Says." Daily Nature and Science News and Headlines National Geographic News. 8 Sept Web. 18 July <http://news.nationalgeographic.com/news/2009/09/ liposuction-leftovers-fatstem-cells.html>. Stem Cell Basics: What are embryonic stem cells? In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2009 [cited Sunday, July 18, 2010] Available at <http://stemcells.nih.gov/info/basics/basics3>

6 Chiang 6 "Stem Cells from Fat Used to Repair Girl's Skull - Health - Cloning and Stem Cells - Msnbc.com."Breaking News, Weather, Business, Health, Entertainment, Sports, Politics, Travel, Science, Technology, Local, US & World News- Msnbc.com. Web. 18 July <http://www.msnbc.msn.com/id/ />. "StemCells: Stem Cell Biology." StemCells, Inc Web. 18 July <http://www.stemcellsinc.com/thetechnology/stemcellbiology.html>. "What Are Adult Stem Cells? [Stem Cell Information]." NIH Stem Cell Information Home Page. Web. 25 July <http://stemcells.nih.gov/info/basics/basics4.asp>. "What Are Stem Cells?" Medical News Today: Health News Web. 18 July <http://www.medicalnewstoday.com/info/stem_cell/whatarestemcells.php>. "What Is a Stem Cell?" - Adult Stem Cells - Therapies and Treatments. Stem Cell Research, Web. 19 July <http://www.stemcellresearchfacts.org/what-is-a-stem-cell/>.

guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research

guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research infoaging guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research WHAT ARE STEM CELLS? Stem cells are cells that, in cell cultures

More information

Stem Cell Quick Guide: Stem Cell Basics

Stem Cell Quick Guide: Stem Cell Basics Stem Cell Quick Guide: Stem Cell Basics What is a Stem Cell? Stem cells are the starting point from which the rest of the body grows. The adult human body is made up of hundreds of millions of different

More information

STEM CELL FACTS. The ISSCR is an independent, nonproft organization providing a global forum for stem cell research and regenerative medicine.

STEM CELL FACTS. The ISSCR is an independent, nonproft organization providing a global forum for stem cell research and regenerative medicine. STEM CELL FACTS The ISSCR is an independent, nonproft organization providing a global forum for stem cell research and regenerative medicine. WHAT ARE STEM CELLS? Stem cells are the foundation cells for

More information

Stem cells possess 2 main characteristics: Sources of pluripotent stem cells: -Long-term self renewal. -The inner cell mass of the blastocyst.

Stem cells possess 2 main characteristics: Sources of pluripotent stem cells: -Long-term self renewal. -The inner cell mass of the blastocyst. Stem cells possess 2 main characteristics: -Long-term self renewal. - They give rise to all types of differentiate cells. Sources of pluripotent stem cells: -The inner cell mass of the blastocyst. - Fetal

More information

The Types of stem cells: Totipotent Pluripotent Multipotent

The Types of stem cells: Totipotent Pluripotent Multipotent Stem Cells is the main material for building and regeneration of the body Stem cells are not differentiated and can transform to any cell of organism Stem cells are capable of indefinite renewal through

More information

It s not something you want to think about, but it s something you want to prepare for.

It s not something you want to think about, but it s something you want to prepare for. It s not something you want to think about, but it s something you want to prepare for. StemCyte cord blood banking offers your family a new lifesaving treatment alternative Why Bank Take the once-in-alifetime

More information

POSITION STATEMENT REGARDING THE USE OF EMBRYONIC AND ADULT HUMAN STEM CELLS IN BIOMEDICAL RESEARCH October 2004

POSITION STATEMENT REGARDING THE USE OF EMBRYONIC AND ADULT HUMAN STEM CELLS IN BIOMEDICAL RESEARCH October 2004 POSITION STATEMENT REGARDING THE USE OF EMBRYONIC AND ADULT HUMAN STEM CELLS IN BIOMEDICAL RESEARCH October 2004 Preamble The American Academy of Neurology (AAN) and the American Neurological Association

More information

15 Stem Cell Research

15 Stem Cell Research 15 Stem Cell Research t a l k it o v e r 1 c l a s s se s s i o n Overview Students read about current scientific research on and the social controversy over embryonic stem cells. On a KWL literacy strategy

More information

What are Stem Cells? How can they be used in medicine?

What are Stem Cells? How can they be used in medicine? What are Stem Cells? How can they be used in medicine? What is a stem cell????... What is a stem cell????......a cell with the ability to differentiate into specialized cells and renew to become more stem

More information

Stem Cells. Part 1: What is a Stem Cell?

Stem Cells. Part 1: What is a Stem Cell? Stem Cells Part 1: What is a Stem Cell? Stem cells differ from other kinds of cells in the body. When a stem cell divides by mitosis, each new cell has the potential to either remain a stem cell or become

More information

Human stem cell research: a novel technology that will benefit patients Information and Position Paper

Human stem cell research: a novel technology that will benefit patients Information and Position Paper October 2003 Human stem cell research: a novel technology that will benefit patients Information and Position Paper EuropaBio, the European Association for Bio-industries, has 35 corporate members operating

More information

your complete stem cell bank

your complete stem cell bank your complete stem cell bank HYDERABAD - 88985 000 888, WARANGAL - 8297 256 777 VISAKHAPATNAM - 7799 990 774 VIJAYAWADA AND GUNTUR - 7799 990 771 NELLORE - 7799 990 772, KADAPA - 8297 256 700 RAJAHMUNDRY

More information

Biology and Society. Unit Five: Human Reproduction. Topic Six: Stem Cell Research

Biology and Society. Unit Five: Human Reproduction. Topic Six: Stem Cell Research Biology and Society Unit Five: Human Reproduction Topic Six: Stem Cell Research The issue of stem cell research burst on the scientific scene in November of 1998 when researchers first reported the isolation

More information

STEM CELL FELLOWSHIP

STEM CELL FELLOWSHIP Module I: The Basic Principles of Stem Cells 1. Basics of Stem Cells a. Understanding the development of embryonic stem cells i. Embryonic stem cells ii. Embryonic germ cells iii. Differentiated stem cell

More information

Chapter 16 Reproductive Technology, Gene Therapy, and Stem Cells (modified)

Chapter 16 Reproductive Technology, Gene Therapy, and Stem Cells (modified) Chapter 16 Reproductive Technology, Gene Therapy, and Stem Cells (modified) Assisted Reproductive Technologies (ART) Artificial insemination (AI) In vitro fertilization (IVF) Gamete intrafallopian transfer

More information

STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE

STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE What are Stem Cells? Stem cells are the basic building blocks of all the cells, tissues and organs in the human body. The role of the stem

More information

Stem Cells and Hope for Patients

Stem Cells and Hope for Patients Stem Cells and Hope for Patients by Maureen Condic, Ph.D. Most Americans know someone afflicted with an incurable medical condition. The possibility of stem cell cures has given hope to many who face such

More information

San Diego Stem Cell Treatment Center Frequently Asked Questions

San Diego Stem Cell Treatment Center Frequently Asked Questions San Diego Stem Cell Treatment Center Frequently Asked Questions What is a Stem Cell? A stem cell is basically any cell that can replicate and differentiate. This means the cell can not only multiply, but

More information

Stem Cells: Scientific Progress and Future Research Directions

Stem Cells: Scientific Progress and Future Research Directions 2001 Terese Winslow Stem Cells: Scientific Progress and Future Research Directions STEM CELLS: SCIENTIFIC PROGRESS AND FUTURE RESEARCH DIRECTIONS June 2001 This page intentionally left blank TABLE OF CONTENTS

More information

Stem Cell Information

Stem Cell Information Stem Cell Information The official National Institutes of Health resource for stem cell research Stem Cell Basics Stem cells have the remarkable potential to develop into many different cell types in the

More information

tem ells /background /information Stem cell research Copyright 2007 MRC Centre for Regenerative Medicine, Institute for Stem Cell Research

tem ells /background /information Stem cell research Copyright 2007 MRC Centre for Regenerative Medicine, Institute for Stem Cell Research tem ells /background /information Stem cell research Copyright 2007 MRC Centre for Regenerative Medicine, Institute for Stem Cell Research /02 /information Table of contents Page 01. What are stem cells?

More information

An Introduction to Stem Cells

An Introduction to Stem Cells By Kirstin Matthews, Ph.D. An Introduction to Stem Cells Overview Stem cells are cells that have the potential to replicate themselves for indefinite periods and to divide, producing one of themselves

More information

Demystifying Stem Cells. Brent Bost M.D., CPA, MBA, FACOG

Demystifying Stem Cells. Brent Bost M.D., CPA, MBA, FACOG Demystifying Stem Cells Brent Bost M.D., CPA, MBA, FACOG Disclaimers Author currently serves on Board of Directors of CordTrack Most applications discussed today are not currently FDA approved and are,

More information

Differentiation = Making specialized cells

Differentiation = Making specialized cells Differentiation = Making specialized cells What is a stem cell? Screws: JM www.logodesignweb.com/stockphoto Differentiation = Making specialized cells What is a stem cell? What the photo shows A lump of

More information

outline What is a stem cell? Tissue stem cell Embryonic stem cell ips cell -production -advantages Applications Issue Conclusion

outline What is a stem cell? Tissue stem cell Embryonic stem cell ips cell -production -advantages Applications Issue Conclusion outline What is a stem cell? Tissue stem cell Embryonic stem cell ips cell -production -advantages Applications Issue Conclusion 1 What is a stem cell? Definition: Self-renew themselves a number of times

More information

Roche Position on Human Stem Cells

Roche Position on Human Stem Cells Roche Position on Human Stem Cells Background Stem cells and treating diseases. Stem cells and their applications offer an enormous potential for the treatment and even the cure of diseases, along with

More information

THE PROMISE OF STEM CELL RESEARCH

THE PROMISE OF STEM CELL RESEARCH THE PROMISE OF STEM CELL RESEARCH MALIGNANT OSTEOPETROSIS AUTOSOMAL RECESSIVE DENSE SCLEROTIC SKELETON HEMATOLOGIC ABNORMALITIES NEUROLOGIC ABNOMALITIES DEATH IN INFANCY OR EARLY CHILDHOOD SUCCESS RATE

More information

Current Issues in Stem Cell Technologies. Lance D. Trainor, MD OneBlood, Inc.

Current Issues in Stem Cell Technologies. Lance D. Trainor, MD OneBlood, Inc. Current Issues in Stem Cell Technologies Lance D. Trainor, MD OneBlood, Inc. Objective: The big picture of stem cell therapy Outline: Relevant definitions History of Stem Cell Therapy Hematopoietic Stem

More information

Guidance For Research Involving Human Embryonic Stem Cells, Germ Cells, And Cells Obtained From Cord Blood

Guidance For Research Involving Human Embryonic Stem Cells, Germ Cells, And Cells Obtained From Cord Blood Guidance For Research Involving Human Embryonic Stem Cells, Germ Cells, And Cells Obtained From Cord Blood Supreme Council of Health Department of Research Guidance Regarding Research Involving Human Embryonic

More information

PART I. SECTION 1. The legislature finds that an estimated. 128,000,000 Americans suffer from the crippling economic and

PART I. SECTION 1. The legislature finds that an estimated. 128,000,000 Americans suffer from the crippling economic and HOUSE OF REPRESENTATIVES TWENTY-FOURTH LEGISLATURE, 2007 STATE OF HAWAII A BILL FOR AN ACT RELATING TO MEDICAL RESEARCH. BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF HAWAII: PART I SECTION 1. The legislature

More information

AP BIOLOGY 2012 SCORING GUIDELINES

AP BIOLOGY 2012 SCORING GUIDELINES AP BIOLOGY 2012 SCORING GUIDELINES Question 1 Note: At least 1 point must be earned from each of parts (a), (b), (c), and (d) in order to earn a maximum score of 10. The ability to reproduce is a characteristic

More information

Purification and Expansion of Hematopoietic Stem Cells Based on Proteins Expressed by a Novel Stromal Cell Population

Purification and Expansion of Hematopoietic Stem Cells Based on Proteins Expressed by a Novel Stromal Cell Population Purification and Expansion of Hematopoietic Stem Cells Based on Proteins Expressed by a Novel Stromal Cell Population Our bodies are constantly killing old, nonfunctional, and unneeded cells and making

More information

Should Stem Cells Be Used To Treat Human Diseases?

Should Stem Cells Be Used To Treat Human Diseases? SAMPLE ESSAY C Should Stem Cells Be Used To Treat Human Diseases? Stem cells can be defined as undifferentiated cells that are generated during the development of the embryo. There are two functions ascribed

More information

the future in your hands imagine

the future in your hands imagine the future in your hands imagine The promise of hope Carrie and Wilf s story... Quinn weighed in at a healthy 4397g at birth. His parents, Carrie and Wilf, had decided to store the umbilical cord blood

More information

Unit 1 Higher Human Biology Summary Notes

Unit 1 Higher Human Biology Summary Notes Unit 1 Higher Human Biology Summary Notes a. Cells tissues organs body systems Division of labour occurs in multicellular organisms (rather than each cell carrying out every function) Most cells become

More information

Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord

Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord Cauley O. Gieb Advanced Health Law HLP Article Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord Today advances in science seem to gain the most recognition and support when the subject

More information

5 Frequently Asked Questions About Adult Stem Cell Research

5 Frequently Asked Questions About Adult Stem Cell Research 5 Frequently Asked Questions About Adult Stem Cell Research Stem cells are often referred to in the sociopolitical realm with some level of controversy and beyond that, some level of confusion. Many researchers

More information

Fact Sheet 22 CLONING AND STEM CELLS

Fact Sheet 22 CLONING AND STEM CELLS 11111 This fact sheet describes the process of cloning and producing stem cells. It outlines the potential benefits, ethical challenges, and provides an overview of the current policies governing the technology.

More information

The Therapeutic Potential of Human Umbilical Cord Blood Transplantation for Neonatal Hypoxic-Ischemic Brain Injury and Ischemic Stroke

The Therapeutic Potential of Human Umbilical Cord Blood Transplantation for Neonatal Hypoxic-Ischemic Brain Injury and Ischemic Stroke The Therapeutic Potential of Human Umbilical Cord Blood Transplantation for Neonatal Hypoxic-Ischemic Brain Injury and Ischemic Stroke a,b* b,c a a b b b b a b a b c 430 Wang et al. Acta Med. Okayama Vol.

More information

Stem Cells and Inner Ear Cell Regeneration. Stefan Heller Stanford University School of Medicine

Stem Cells and Inner Ear Cell Regeneration. Stefan Heller Stanford University School of Medicine Stem Cells and Inner Ear Cell Regeneration Stefan Heller Stanford University School of Medicine Embryonic stem cells Induced pluripotent stem cells Somatic stem cells 50 µm Derived from the inner cell

More information

Saving Cord Tissue for Your Family

Saving Cord Tissue for Your Family Saving Cord Tissue for Your Family Dear Future Mom and/or Dad, All of us at CorCell would like to give you a big CONGRATULATIONS on your pregnancy! Now that you are expecting, you have probably heard about

More information

Stem Cells for Life. (301) 654-7070 www.facialart.com

Stem Cells for Life. (301) 654-7070 www.facialart.com Stem Cells for Life Dr. H. Ryan Kazemi Board Certified Oral & Maxillofacial Surgeon (301) 654-7070 www.facialart.com 4825 Bethesda Ave., #310 Bethesda, MD 20814 Researchers feel that stem cells could have

More information

Stem cells will change medicine as we know it. Are you ready? STEM CELL BANKING

Stem cells will change medicine as we know it. Are you ready? STEM CELL BANKING Stem cells will change medicine as we know it. Are you ready? STEM CELL BANKING Stem cell banking with Store-A-Tooth is a unique investment in the health of your family. WHY BANK STEM CELLS? YOU PLAN FOR

More information

Support structure for genetic material

Support structure for genetic material Support structure for genetic material 1 Making proteins in the RER Making copies of humans 2 Making copies of cells Making copies of genetic material 3 Making copies of genetic material Making copies

More information

Cord blood for the treatment of acute lymphoblastic leukemia in young children

Cord blood for the treatment of acute lymphoblastic leukemia in young children Cord blood for the treatment of acute lymphoblastic leukemia in young children By Caitlin McGreevy Kiara Paramjothy Pass with Merit RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2011 1 Abstract:

More information

Chapter 2 The different types of stem cells

Chapter 2 The different types of stem cells Chapter 2 The different types of stem cells This chapter investigates the two main types of stem cells, each with their own subcategories: 1. Pluripotent stem cells can become any cell type in the body.

More information

Top Ten Things to Know About Stem Cell Treatments

Top Ten Things to Know About Stem Cell Treatments Top Ten Things to Know About Stem Cell Treatments Many clinics that are offering stem cell treatments make claims about what stem cells can and cannot do that are not supported by our understanding of

More information

Stem Cell Therapy. THE DARK AND BRIGHT ASPECTS of Stem Cell Therapy

Stem Cell Therapy. THE DARK AND BRIGHT ASPECTS of Stem Cell Therapy Stem Cell Therapy THE DARK AND BRIGHT ASPECTS of Stem Cell Therapy Stem Cells Our last Weapon? The last weapon in the medical armamentarium? Bye the way.. What IS a last weapon? I don t know about today,

More information

ADULT STEM CELLS: THE ONLY ONES THAT REALLY HELP

ADULT STEM CELLS: THE ONLY ONES THAT REALLY HELP 1 ADULT STEM CELLS: THE ONLY ONES THAT REALLY HELP Almost every time we pick up the paper, there is an article on stem cells. It can be very confusing. Here are some simple definitions that can help. Stem

More information

Background Information

Background Information Background Information 1. What are stem cells? 2. What might stem cell research achieve? 3. Why we need to continue research using embryonic stem cells? 4. Time taken for discoveries 5. Examples of stem

More information

Stem cell research ACADEMY STATEMENT. progress, hopes and concerns ACADEMY STATEMENT 16 JANUARY 2013

Stem cell research ACADEMY STATEMENT. progress, hopes and concerns ACADEMY STATEMENT 16 JANUARY 2013 ACADEMY STATEMENT 16 JANUARY 2013 ACADEMY STATEMENT Stem cell research progress, hopes and concerns KUNGL. VETENSKAPSAKADEMIEN, BOX 50005, SE-104 05 STOCKHOLM, SWEDEN TEL +46 8 673 95 00, FAX +46 8 15

More information

4. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.

4. All cord blood banks should be subject to the same standards, regulations and accreditation requirements. WMDA Policy Statement on the Utility of Autologous or Family Cord Blood Unit Storage The WMDA Board adopted this policy on 25 th of May 2006. Policy updated _April 2011 The Cord Blood Working Group and

More information

Introducing stem cells

Introducing stem cells Introducing stem cells 1 Dear speaker This presentation is intended as a flexible tool for scientists, science communicators and educators. Not all the slides will be useful for any one occasion. Choose

More information

Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease

Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease 1 Produced by St. Jude Children s Research Hospital Departments of Hematology, Patient

More information

Biotechnology. Srivatsan Kidambi, Ph.D.

Biotechnology. Srivatsan Kidambi, Ph.D. Stem Stem Cell Cell Engineering-What, Biology and it Application Why, How?? to Biotechnology Srivatsan Kidambi, Ph.D. Assistant Professor Department of Chemical & Biomolecular Engineering University of

More information

Patient Handbook on Stem Cell Therapies

Patient Handbook on Stem Cell Therapies Patient Handbook on Stem Cell Therapies Appendix I of the Guidelines for the Clinical Translation of Stem Cells www.isscr.org 2008, International Society for Stem Cell Research 2 Introduction We have all

More information

[Indian Stem Cell Banking Market: Trends & Opportunities (2012-2017)]

[Indian Stem Cell Banking Market: Trends & Opportunities (2012-2017)] [Indian Stem Cell Banking Market: Trends & Opportunities (2012-2017)] Executive Summary Stem Cells have a remarkable ability to develop in various body cells of a human. These occur in the earliest stages

More information

Biology Ch 10 Cell Growth & Division ( )

Biology Ch 10 Cell Growth & Division ( ) Name Class Date Biology Ch 10 Cell Growth & Division (10.1-10.2) For Questions 1 4, write True if the statement is true. If the statement is false, change the underlined word or words to make the statement

More information

cord blood saves lives...

cord blood saves lives... cord blood saves lives... ...by providing a rich source of blood stem cells that can be used to treat over 80 different diseases including leukemia, lymphoma, thalassemia, Tay-Sachs and sickle cell anemia.

More information

Research: Stem Cells. What are Stem Cells?

Research: Stem Cells. What are Stem Cells? What are Stem Cells? Have you ever thought about where you come from? How you were made? How did you grow from two tiny cells from your mother and father into a human mass of cells all performing independent

More information

Briefing on the second reading of the Human Fertilisation and Embryology Bill, Monday 19 November 2007.

Briefing on the second reading of the Human Fertilisation and Embryology Bill, Monday 19 November 2007. Briefing on the second reading of the Human Fertilisation and Embryology Bill, Monday 19 November 2007. Prepared by the Medical Research Council, Royal Society and Wellcome Trust The Medical Research Council,

More information

Genetics, Ethics &Meaning. Module 4

Genetics, Ethics &Meaning. Module 4 Genetics, Ethics &Meaning INItiative (GEMINI) Life Sciences and Society @University of Michigan Module 4 Myths versus Facts The University of Michigan s Stem Cell Research Environment A Case Study MYTH:

More information

07 SB148/FA/1 A BILL TO BE ENTITLED AN ACT

07 SB148/FA/1 A BILL TO BE ENTITLED AN ACT 0 SB/FA/ Senate Bill By: Senators Shafer of the th, Staton of the th, Thomas of the th, Rogers of the st, Heath of the st and others A BILL TO BE ENTITLED AN ACT AS PASSED SENATE 0 To amend Title of the

More information

The Prospect of Stem Cell Therapy in Multiple Sclerosis. Multiple sclerosis is a multifocal inflammatory disease of the central

The Prospect of Stem Cell Therapy in Multiple Sclerosis. Multiple sclerosis is a multifocal inflammatory disease of the central The Prospect of Stem Cell Therapy in Multiple Sclerosis Multiple sclerosis is a multifocal inflammatory disease of the central nervous system that generally affects young individuals, causing paralysis

More information

An Introduction to Stem Cell Biology. Michael L. Shelanski, MD,PhD Professor of Pathology and Cell Biology Columbia University

An Introduction to Stem Cell Biology. Michael L. Shelanski, MD,PhD Professor of Pathology and Cell Biology Columbia University An Introduction to Stem Cell Biology Michael L. Shelanski, MD,PhD Professor of Pathology and Cell Biology Columbia University Figures adapted from ISSCR. Presentations of Drs. Martin Pera (Monash University),

More information

Differentiation = Making specialized cells. Your body needs stem cells. What is a stem cell?

Differentiation = Making specialized cells. Your body needs stem cells. What is a stem cell? Differentiation = Making specialized cells What is a stem cell? What the photo shows A lump of metal and lots of different kinds of screws. Things to think about Lumps of metal that start off the same

More information

Stem Cell Basics. About this document. I. Introduction: What are stem cells, and why are they important?

Stem Cell Basics. About this document. I. Introduction: What are stem cells, and why are they important? Stem Cell Basics Last modified on April 08, 2015 About this document This primer on stem cells is intended for anyone who wishes to learn more about the biological properties of stem cells, the important

More information

Stem Cell Therapy In Diabetes Mellitus. Professor Megahid Abuelmagd Diabetes And Endocrine Unit. Mansoura Faculty Of Medicine

Stem Cell Therapy In Diabetes Mellitus. Professor Megahid Abuelmagd Diabetes And Endocrine Unit. Mansoura Faculty Of Medicine Stem Cell Therapy In Diabetes Mellitus Professor Megahid Abuelmagd Diabetes And Endocrine Unit. Mansoura Faculty Of Medicine For many years, there has been great interest in approaches to the replacement

More information

06 LC 14 9480S A BILL TO BE ENTITLED AN ACT

06 LC 14 9480S A BILL TO BE ENTITLED AN ACT 0 LC 0S The House Committee on Health and Human Services offers the following substitute to SB : A BILL TO BE ENTITLED AN ACT 0 To amend Title of the Official Code of Georgia Annotated, relating to health,

More information

5. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.

5. All cord blood banks should be subject to the same standards, regulations and accreditation requirements. WMDA Policy Statement for the Utility of Autologous or Family Cord Blood Unit Storage (This policy statement has been approved and adopted by the WMDA board on the 25 th of May 2006) The Cord Blood Registries

More information

Human Embryonic Stem Cell Research Frequently Asked Questions and Fact Sheet

Human Embryonic Stem Cell Research Frequently Asked Questions and Fact Sheet Human Embryonic Stem Cell Research Frequently Asked Questions and Fact Sheet Stem Cell Science Basics What are stem cells? Stem cells are naturally occurring cells that are not yet fully differentiated.

More information

Knowledge in Motion SCI Education Series

Knowledge in Motion SCI Education Series Knowledge in Motion SCI Education Series Neuroregenerative Properties of Dental Pulp Stem Cells and their Future Potential to Improve Neurological Outcomes in SCI Ricardo Battaglino, PhD Alpdogan Kantarci,

More information

Cell Division Mitosis and the Cell Cycle

Cell Division Mitosis and the Cell Cycle Cell Division Mitosis and the Cell Cycle A Chromosome and Sister Chromatids Key Points About Chromosome Structure A chromosome consists of DNA that is wrapped around proteins (histones) and condensed Each

More information

Muscular Dystrophy: Stem Cell Therapy

Muscular Dystrophy: Stem Cell Therapy by Caitlin Pederson Abstract: Genetic disorders affect many people, and muscular dystrophy is a disorder that can greatly decrease the quality of life. Finding treatment to stop or prevent the loss of

More information

PT CordLife Indonesia Premium Cordblood Bank. PT CordLife Indonesia Premium Cordblood Bank

PT CordLife Indonesia Premium Cordblood Bank. PT CordLife Indonesia Premium Cordblood Bank Cordblood Stem Cells and The Role of Cordblood Bank in Supporting Stem Cells Research Presentation Overview Company profile Haematopoietic stem cells in cordblood What we can do to help 1 2 PT CordLife

More information

THE PROMISE OF STEM CELLS

THE PROMISE OF STEM CELLS June 2002 THE PROMISE OF STEM CELLS FROM RESEARCH TO MEDICAL THERAPIES As scientists search for treatments for disease, they often benefit from breakthroughs in understanding the basic biology of the cell.

More information

Stem Cell Research. Debate motion

Stem Cell Research. Debate motion Stem Cell Research Debate motion This house proposes that the potential benefits of using embryonic stem cells to develop new medical treatments mean we have a moral obligation to support this type of

More information

Embryo Clay Model Embryogenesis and Stem Cell Development

Embryo Clay Model Embryogenesis and Stem Cell Development Embryo Clay Model Embryogenesis and Stem Cell Development Objective: To identify stages and locations of early embryonic development To see at what point stem cells are totipotent, pluripotent, and multipotent

More information

Stem cells and motor neurone disease

Stem cells and motor neurone disease Stem cells and motor neurone disease F Stem cell research has fuelled hope of a treatment for a variety of conditions. This information sheet explains what these cells are and includes details of the current

More information

The Facts about Cord Blood

The Facts about Cord Blood The Facts about Cord Blood Dear Future Mom and/or Dad, All of us at CorCell would like to give you a big CONGRATULATIONS on your new baby! Now that you are expecting, you have probably heard about saving

More information

National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council

National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council IN THIS BOOKLET... WHAT IS A STEM CELL? 3 TYPES OF STEM CELLS 4 WORKING WITH STEM CELLS 9 WHY

More information

RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2014

RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2014 THE DEVELOPMENT OF STEM CELL RESEARCH AND TREATMENTS WITHIN MEDICINE BY JENNA BUXTON Grade awarded: Pass with Merit RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2014 ABSTRACT This paper discusses

More information

Stem Cell Research & Human Cloning

Stem Cell Research & Human Cloning Stem Cell Research & Human Cloning Topics for Discussion Clarify the scientific and moral definition of cloning Discuss the facts about stem cells, therapies, and cures Learn the truth about the Church

More information

Stem cells now and in the future: regulation in Australia

Stem cells now and in the future: regulation in Australia John Skerritt National Manager Therapeutic Goods Administration ARCS Scientific Congress 2015 5 May 2015 n biologicals regulatory scheme introduced May 2011 (fully in place by 2014) to: Sets standards

More information

Ethical Considerations For Using Stem Cells

Ethical Considerations For Using Stem Cells Ethical Considerations For Using Stem Cells By: David Rocheleau There are many times in one s life and career where we face ethical decisions or dilemmas. These instances may be presented to us on a daily

More information

RITMIR024 - STEM CELL RESEARCH IN CARDIOLOGY

RITMIR024 - STEM CELL RESEARCH IN CARDIOLOGY 1. SCOPE AND METHODOLOGY 2. REPORT SYNOPSIS 2.1 General Definitions Myoblasts Pluripotent Cells Multipotent Cells Progenitor Cells Role of Stem Cells in Repairing the Heart Stem Cell Therapy Stem Cells

More information

Brochure More information from http://www.researchandmarkets.com/reports/2860999/

Brochure More information from http://www.researchandmarkets.com/reports/2860999/ Brochure More information from http://www.researchandmarkets.com/reports/2860999/ Stem Cells: Worldwide Markets for Transplantation and Cord Blood Banking (Projections for Stem Cell Use in Cancer, Alzheimer

More information

STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA

STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA OVO CLINIC I 8000 BLVD DECARIE, MONTREAL QC H4P 2S4 I 514.798.2000 I OVOCLINIC.COM 2 a therapeutic revolution As the

More information

Elena Bryzgalina. Bioethical and Legal Regulation of the Use of Stem Cells and Stem Cell Technologies in Modern Russia

Elena Bryzgalina. Bioethical and Legal Regulation of the Use of Stem Cells and Stem Cell Technologies in Modern Russia Bioethical and Legal Regulation of the Use of Stem Cells and Stem Cell Technologies in Modern Russia Elena Bryzgalina PhD, Member of the committee on bioethics of the Lomonosov s Moscow State University,

More information

Stem Cell Therapy. Treat your pain, improve your lifestyle and look after your wellbeing. What are stem cells?

Stem Cell Therapy. Treat your pain, improve your lifestyle and look after your wellbeing. What are stem cells? (02) 9824 3044 LIVERPOOL NSW 2170 Stem Cell Therapy Treat your pain, improve your lifestyle and look after your wellbeing What are stem cells? Stem cells are cells that can differentiate into other types

More information

CORD BLOOD BANKING FAQ

CORD BLOOD BANKING FAQ CORD BLOOD BANKING FAQ Cord Blood & Stem Cells Q: What is umbilical cord blood (UCB)? A: Bone marrow, peripheral blood and UCB constitute the three primary sources of stem cells. Cord blood, which, until

More information

REGENERATIVE MEDICINE

REGENERATIVE MEDICINE MAKING THE IMPOSSIBLE POSSIBLE CENTER FOR > SOLUTIONS AND HOPE Millions of people worldwide suffer from deadly diseases, chronic conditions and congenital disorders that today have no cure. Using currently

More information

Bone Marrow or Blood Stem Cell Transplants in Children With Severe Forms of Autoimmune Disorders or Certain Types of Cancer

Bone Marrow or Blood Stem Cell Transplants in Children With Severe Forms of Autoimmune Disorders or Certain Types of Cancer Bone Marrow or Blood Stem Cell Transplants in Children With Severe Forms of Autoimmune Disorders or Certain Types of Cancer A Review of the Research for Parents and Caregivers Is This Information Right

More information

Save up to 25% off stem cell banking with Netcells Biosciences

Save up to 25% off stem cell banking with Netcells Biosciences Save up to 25% off stem cell banking with Netcells Biosciences In a unique offering, we have been able to arrange an exclusive offer for medical scheme members with Netcells Biosciences Africa s leading

More information

H. R. 2107 IN THE HOUSE OF REPRESENTATIVES

H. R. 2107 IN THE HOUSE OF REPRESENTATIVES I 1TH CONGRESS 1ST SESSION H. R. 2107 To direct the Secretary of Health and Human Services to conduct a public education campaign on umbilical cord blood stem cells, and for other purposes. IN THE HOUSE

More information

Introducing stem cells Stem cells in the news

Introducing stem cells Stem cells in the news Introducing stem cells Stem cells in the news Stem cells: Therapeutic Value 16+ year olds February 2010, updated 2012 Objective: Understand the therapeutic value of stem cells About tissue stem cells Stem

More information

Stem cells state of the ART

Stem cells state of the ART Stem cells state of the ART Pluripotent stem cells in ART how far are we? Peter Kragh SPIREN FERTILITETSKLINIKK & FERTILITETSSEKSJONEN, ST OLAVS HOSPITAL Today: - Stem cells: origin, development - Embryonic

More information

CORD BLOOD TRANSPLANTATION STUDY EXPANDED ACCESS PROTOCOL APPENDIX A SAMPLE CONSENT FORM

CORD BLOOD TRANSPLANTATION STUDY EXPANDED ACCESS PROTOCOL APPENDIX A SAMPLE CONSENT FORM APPENDIX A SAMPLE CONSENT FORM CORD BLOOD TRANSPLANTATION (COBLT) STUDY SAMPLE CONSENT FORM FOR THE EXPANDED ACCESS PROTOCOL You (your child) are being asked to take part in a clinical research study.

More information

Stem cells and motor neurone disease

Stem cells and motor neurone disease Stem cells and motor neurone disease F Stem cell research has fuelled hope of a treatment for a variety of conditions. This information sheet explains what these cells are and how they may be used to create

More information

Human Body Systems. Body Organization and Homeostasis

Human Body Systems. Body Organization and Homeostasis Human Body Systems Body Organization and Homeostasis Objectives Describe how the human body is organized Explain homeostasis Organization of the Body Every cell in the human body is both an independent

More information