ÖZGEÇMĐŞ. Araştırma ilgi Alanı: Klinik Biyokimya, Serbest radikaller, Adipositokinler, Diabetes mellitus, Metabolik sendrom
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1 ÖZGEÇMĐŞ Kişisel Bilgiler Soyadı:...ÜSTÜNDAĞ Adı:.... BĐLAL Akademik Unvanı/Görevi: Prof.Dr./Öğretim Üyesi Mesleki ve Profesyonel Anahtar Nitelik ve Becerileri: Araştırma ilgi Alanı: Klinik Biyokimya, Serbest radikaller, Adipositokinler, Diabetes mellitus, Metabolik sendrom Uluslar arası Deneyim/Đşbirlikleri: Đletişim Bilgileri Đş adresi: Hastane Adı: Fırat Üniversitesi Hastanesi Cadde: Şehir: Ülke: ELAZIĞ TÜRKĐYE Posta Kodu: Telefon / Faks E-posta: drbustundag@yahoo.com Doğum tarihi: Doğduğu Yer ve Ülke: Uyruğu: Eğitim Gördüğü Ülke: Ana Dili: Bildiği Yabancı Dil: Karakoçan /ELAZIĞ-TÜRKĐYE T.C. TÜRKĐYE TÜRKÇE ĐNGĐLĐZCE
2 Akademik Bilgiler Fakülte/Üniversite (adı ve adresi): ĐSTANBUL ÜNĐVERSĐTESĐ TIP FAKÜLTESĐ-ĐSTANBUL-TÜRKĐYE Mezuniyet tarihi: Mezuniyet Sonrası Eğitimi: (Kurumun Adı ve adresi, Mezuniyet Sonrası Eğitim Danışmanları) Tıpta uzmanlık (Biyokimya ve Klinik Biyokimya AD), Fırat Üniversitesi Tıp Fakültesi-ELAZIĞ-TÜRKĐYE) Tez Danışmanları: Prof.Dr.Necip ĐLHAN Başlama Bitirme Tıpta Uzmanlık Tez başlığı: Deneysel diabetes mellitus oluşturulmuş ratlarda Renin-Angiotensin-Aldosteron sisteminin incelenmesi) Akreditasyon: Fırat Üniversitesi, T.C. Sağlık Bakanlığı [Akreditasyon Kurumu (Üniversite, Tıbbi Dernek veya Resmi Kurum)] Akademik Deneyim: Tıp Fakültesi sınıf Biyokimya, Klinik biyokimya dersleri Sağlık Hizmetleri Meslek yüksek okulu Tıbbi Laboratuvar- Anestezi programları, Biyokimya, Klinik biyokimya dersleri Tıpta uzmanlık alanında ders vermek Asistan eğitimi ( 1 yüksek lisans 2 doktora 3 Tıpta uzmanlık öğrencisi yetiştirildi) Devam eden 2 tıpta uzmanlık öğrencisi) Klinik Laboratuvar yönetimi Üyesi Olduğu Meslek Kuruluşları: Türk Biyokimya Derneği Türk Klinik Biyokimya Derneği Klinik Biyokimya Uzmanları Derneği
3 Uluslar arası Yayınlar M-l. AI. Gunal, H. Celiker, H. Celebi, B.Ustundag, SY. Gunal. Intravenous. Alfacalcidol Improves in Hemodialysis Patients. Clinical Nephrology,Vol 48(2); , M-2. A. Semercioz, H. Kelestimur, B. Ustundag, AK. Baltacı, H. Yekeler, M. Sarsılmaz and I. Halifeoglu. Plasma renin activity and kidney damage in response to acute renal ischaemia and ramipril treatment in ovariectomised and uninephrectomised rats. Medical Sciences Research, 25: , M-3. IH. Bahcecioglu, A. Demir, B. Ustundag, M. Ilhan, G. Baydas, H. Canatan, and IH. Ozercan. Protective effect of L.Camitine on alcoholic fatty liver in rats. Medical Science Research, 27; , M-4. B. Ustundag, M. Cay, M. Naziroglu, N. Dilsiz, MJC Crabbe, and N. llhan. The study of renin angiotensin aldosterone in experimental diabetes mellitus. Cell Biochem and Function 17; , M-5. IH. Bahcecioglu, B. Ustundag, IH. Ozercan, E. Ercel, G. Baydas. T. Akdere, A. Demir. Protective effect of Ginkgo Biloba extract on CCL 4 - induced liver damage. Hepatology Research 15; , M-6. M. Naziroglu, M. Cay, B. Ustundag, M. Aksakal and H. Yekeler. Protective effects of vitamin E on carbon tetrachloride induced liver damage in rats. Cell Biochem and Function, 17: , M-7. B. Ustundag, H. Canatan, N. Cinkilinc, I. Halifeoglu and IH. Bahcecioglu. Angiotensin converting enzyme (ACE) activty levels in Insulin-independent diabetes mellitus and effect of ACE levels on diabetic patients with nephropathy. Cell Biochem and Function, 18: 23-28, M-8 HE. Aksulu, I. Bingol, F. Karatas, H.Sagmanligil, B. Ustundag. Changes in plasma angiotensin converting enzyme activty and noradrenaline responses to long term nitric oxide inhibition vary depending on their basal values in chickens. Physiol Res. 49; , M-9. HS. Ozdemir, HE. Aksulu, F. Karatas, B. Ustundag, I. Bingol. Long term Lisinopril dihydrate application decreases plasma noradrenaline but not adrenaline levels in chickens. Physiol Res. 49; , M-10. A. Kazez, M. Demirbag, B. Ustundag. IH. Ozercan and M. Saglam. The role of melatonin in prevention of intestinal Ischemia-reperfusion injury in rats. Journal ofpediatric Surgery. Vol 35; 10, , M-11. Rahman A, Ustunda B, Burma O, Özercan ĐH, Çekirdekçi A, Bayar MK. Does aprotinin reduce lung perfusion damage after cardiopulmonary By pass. Eureapean Journal of CardioThoracic Surgery, 18(5); , 2000.
4 M-12 B Ustundag, A. Kazez, M. Demirbag, H. Canatan, I. Halifeoglu, and IH. Ozercan. Protective effect of melatonin on antioxidative system in experimental ischemia-reperfusion of rat small ntestine. Cellular Physiology and Biochemistry.10 (4); , M-13. I.Halifeoglu, H.Canatan, Ustundag B., N.Ilhan, F. Inane. Effect of thinner inhalation on lipid peroxidation and some antioxidant enzymes of people working with paint thinner. Cell Biochem and Function, 18 (4); , Dec M-14. Ali Rahman, Bilal Ustundag, Oktay Burma Đ.Hanifi Özercan, Fatih Serhat Erol. Neuroprotective effect of regional carnitine on spinal cord ischemia-reperfusion injury.european J of Cardio-Thoarcic Surgery 20 (1): JUL M-15 Đrfan kaygusuz, Ahmet Öztürk, Bilal Ustundag, Şinasi Yalçın. Role of free oxygen radicals in noiserelated hearing impairment. Hearing Research 62 (1-2): DEC 2001 M-16. Ustundag B. ACE in diabetes mellitus: Dr.Bilal Ustundag replies. Letter to Editor, Cell Biochem and Function, 19, (1): Mar M-17.Karlidag T, Yalcin S, Ozturk A, Ustundag B, Gok U, Kaygusuz I, Susaman N. The role of free oxygen radicals in noise induced hearing loss:effects of melatonin and methylprednisolone. Auris Nasus Larynx Apr;29(2): M-18.Atmaca M, Kuloglu M, Tezcan E, Ustundag B, Gecici O, Firidin B. Serum leptin and cholesterol values in suicide attempters. Neuropsychobiology. 2002;45(3): M-19. Kuloglu M, Ustundag B, Atmaca M, Canatan H, Tezcan AE, Cinkilinc N. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct Jun;20(2): M-20. Atmaca M, Kuloglu M, Tezcan E, Gecici O, Ustundag B. Serum cholesterol and leptin levels in patients with borderline personality disorder. Neuropsychobiology. 2002;45(4): M-21. Kuloglu M, Atmaca M, Tezcan E, Gecici O, Tunckol H, Ustundag B. Antioxidant enzyme activities and malondialdehyde levels in patients with obsessive-compulsive disorder. Neuropsychobiology. 2002;46(1): M-22.Gunal AI, Celiker H, Akpolat N, Ustundag B, Duman S, Akcicek F. By reducing production of vascular endothelial growth factor octreotide improves the peritoneal vascular alterations induced by hypertonic peritoneal dialysis solution. Perit Dial Int May-Jun;22(3): M-23.Atmaca M, Kuloglu M, Tezcan E, Semercioz A, Ustundag B, Ayar A. Serum leptin levels in patients with premature ejaculation. Arch Androl Sep-Oct;48(5):
5 M-24. Atmaca M, Kuloglu M, Tezcan E, Onal S, Ustundag B. Neopterin levels and dexamethasone suppression test in posttraumatic stress disorder. Eur Arch Psychiatry Clin Neurosci Aug; 252(4): M-25. Atmaca M, Kuloglu M, Tezcan E, Ustundag B. Weight gain and serum leptin levels in patients on lithium treatment. Neuropsychobiology. 2002;46(2):67-9. M-26. Atmaca M, Kuloglu M, Tezcan E, Ustundag B, Bayik Y. Serum leptin and cholesterol levels in patients with bipolar disorder. Neuropsychobiology. 2002;46(4):176-9 M-27. Kuloglu M, Atmaca M, Tezcan E, Ustundag B, Bulut S. Antioxidant enzyme and malondialdehyde levels in patients with panic disorder. Neuropsychobiology. 2002;46(4): M-28.Yılmaz S, Ustundag B. The levels of pyruvate kinase activity in renal and hepatic tissues of rats with diabetes induced by streptozotocin. Turkish Journal of Veterinary and Animal Sciences 26(3); , M-28.Atmaca M, Kuloglu M, Tezcan E, Ustundag B, Semercioz A. Serum leptin levels in patients with premature ejaculation before and after citalopram treatment.bju Int.2003 Feb;91(3): M-29. Atmaca M, Kuloglu M, Tezcan E, Gecici O, Ustundag B. Weight gain, serum leptin and triglyceride levels in patients with schizophrenia on antipsychotic treatment with quetiapine, olanzapine and haloperidol. Schizophr Res Mar 1;60(1): M-30.Kuloglu M, Atmaca M, Ustundag B, Canatan H, Gecici O, Tezcan E. Serum iron levels in schizophrenic patients with or without akathisia. Eur Neuropsychopharmacol Mar;13(2): M-31. Gunal AI, Celiker H, Ustundag B, Akpolat N, Dogukan A, Akcicek F. The effect of oxidative stress inhibition with trimetazidine on the peritoneal alterations induced by hypertonic peritoneal dialysis solution. J Nephrol Mar-Apr;16(2): M-32.Tezcan E, Atmaca M, Kuloglu M, Ustundag B. Free radicals in patients with post-traumatic stress disorder. Eur Arch Psychiatry Clin Neurosci Apr;253(2): M-33. Atmaca M, Kuloglu M, Tezcan E, Ustundag B. Serum leptin and triglyceride levels in patients on treatment with atypical antipsychotics. J Clin Psychiatry May;64(5): M-34. Bulbuller N, Sapmaz E, Akpolat N, Ustundag B, Kirkil C. Effect of a bioresorbable membrane on postoperative adhesions and wound healing. J Reprod Med Jul;48(7): M-35. Atmaca M, Kuloglu M, Tezcan E, Ustundag B. Nizatidine treatment and its relationship with leptin levels in patients with olanzapine-induced weight gain. Hum Psychopharmacol Aug;18 (6):
6 M-36. Atmaca M, Kuloglu M, Tezcan E, Ustundag B. Serum leptin and cholesterol levels in schizophrenic patients with and without suicide attempts. Acta Psychiatr Scand Sep;108(3): M-37. Atmaca M, Kuloglu M, Tezcan E, Ustundag B, Kilic N. Nizatidine for the treatment of patients with quetiapine-induced weight gain. Hum Psycho Pharmacol Jan; 19(1): M-38. Kilic M, Taskin E, Ustundag B, Aygun AD. The evaluation of serum leptin level and other hormonal parameters in children with severe malnutrition. Clin Biochem.2004 May;37(5): M-39 Atmaca M, Tezcan E, Kuloglu M, Ustundag B, Tunckol H. Antioxidant enzyme and malondialdehyde values in social phobia before and after citalopram treatment. Eur Arch Psychiatry Clin Neurosci Aug;254(4): M-40. Bahcecioglu IH, Yalniz M, Ataseven H, Bulbuller N, Kececi M, Demirdag K, Ozercan I, Ustundag B. TNF-alpha and leptin in experimental liver fibrosis models induced by carbon tetrachloride and by common bile duct ligation. Cell Biochem Funct Nov-Dec; 22 (6): M-41.Atmaca M, Tezcan E, Kuloglu M, Ustundag B. Serum leptin levels in obsessive-compulsive disorder.psychiatry Clin Neurosci Apr;59(2): M-42. Aygun AD, Gungor S, Ustundag B, Gurgoze MK, Sen Y. Proinflammatory cytokines and leptin are increased in serum of prepubertal obese children. Mediators Inflamm Aug 14; 2005 (3): M-43. Apak S, Kazez A, Ozel SK, Ustundag B, Akpolat N, Kizirgil A. Spot urine 5-hydroxyindoleacetic acid levels in the early diagnosis of acute appendicitis. J Pediatr Surg Sep;40(9): M-44. Atmaca M, Tezcan E, Kuloglu M, Kirtas O, Ustundag B. Serum folate and homocysteine levels in patients with obsessive-compulsive disorder. Psychiatry Clin Neurosci. 2005Oct; 59(5): M-45. Atmaca M, Tezcan E, Kuloglu M, Ustundag B. Plasma nitrate values in patients with obsessivecompulsive disorder. Psychiatry Clin Neurosci Oct; 59(5): M-46. Bilal Ustundag, Erdal Yilmaz, Yasar Dogan, Saadet Akarsu, Halit Canatan, Ihsan Halifeoglu, Gurkan Cikim, A. Denizmen Aygun. Levels of Cytokines (IL-1ß, IL-2, IL-6, IL-8, TNF-a) and Trace Elements (Zn, Cu) in Breast Milk from Mothers of Preterm and Term Infants. Mediators Inflamm 2005 Dec 14; (6): M-47. Berilgen MS, Bulut S, Ustundag B, Tekatas A, Ayar A Patients with multiple sclerosis have higher levels of serum ghrelin. Neuro Endocrinol Lett Dec 28;26(6) M-48. Omer Geçici, Murat Kuloglu, Murad Atmaca, AE.Tezcan, Hikmet Tunçkol, HM.Emül and Bilal Ustundag. High serum leptin levels in depressive disorders with atypical features. Psychiatry and Clin Neurosci Oct; 59:
7 Uluslar arası Bilimsel toplantılarda Sunumlar B-l. B. Ustundag. M. Cay, M. Naziroglu, N. Dilsiz, MJC. Crabbe, N. Ilhan, and IH. Ozercan. Effect of vitamin E on serum glucose levels and complications of nephropathy in streptozotocm-induced diabetic rats. Sixth International Symposium The Maillard Reaction, p-84. Royal College of Physicians, London UK, July 1997 B-2. B. Ustundag, M.Cay, M.Naziroglu, N. tlhan, N. Dilsiz, and MJC. Crabbe. The study of renin-angiotensin aldosterone in experimental diabetes mellitus rats. Sixth International Symposium The Maillard Reaction, p-121, Royal College of Physicians, London UK, July B-3. M. Naziroglu, M. Cay, I. Canpolat, B. Ustundag, L. Canpolat, N. Aydilek. Protective role of vitamin E and selenium in enflurane anaestheised rats. Stress of Life, Stress and Adaptation from Molecules to man, S-15, Budapest- Hungary, 1-5 July B-4. M. Cay, M. Naziroglu, B. Ustundag, and M. Aksakal. Protective effects of selenium and vitamin E against oxidation stress of cigarette smoke in rats. Stress of Life, Stress and Adaptation from Molecules to man, S-16, Budapest- Hungary, 1-5 July B-5. IH. Bahcecioglu, B. Ustundag, I. Ozercan, T. Akdere. Protective effect of Gingko Biloba extract on CCL4-induced liver damage. Digestion, World Congresses of Gastroenterology, FoN03585, 59(suppl 3); 531, September 6-11, Vienna, Austria, B-6. H. Sagmanligil, HE. Aksulu, F. Karatas, B. Ustundag, I. Bingol, A Kaya. Long tem lisinopril dihydrate application decrases plasma noradrenaline but not adrenaline levels in chickens. XIIIth International Congress of Pharmacology, Nauny Schmiedbergs Arch of Pharmacol, 125th, Supplement 1 to volume 358 No1, 1998, P , july 1998, München-Germany. B-7. HE. Aksulu, I.Bingol, F. Karatas, H. Sagmanlihgil, B. Ustundag. Changes in plasma angiotensin converting enzyme activity (ACE) and noradrenaline responses to long term nitric oxide inhibition vary depending on their basal values in chickens. Proceedings of the International Symposium, Nitric Oxide From Molecular Level to Clinical Application, p-27, Bratislava, June 27-29, B-8. HE. Aksulu, t. Bingol, H. Sagmanligil, B. Ustundag., F. Karatas. N 10 -Nitro-L-arginine decreases plasma renin (PRA) and angiotensin converting enzyme activities (ACE) and noradrenaline level without changing blood pressure in chickens. Proceedings of the International Symposium, Nitric Oxide From Molecular Level to Clinical Application, p-27, Bratislava, June 27-29, B-9. M. Cay, M. Naziroglu, B. Ustundag, H. Simsek, N. Aydiiek, R. Yiice, M. Aksakal. Effects of intraperitoneally adminstered vitamin C on antioxidative defence mechanism in streptozotocin induced
8 diabetic rats. Physiological Research, Formerly Phsyiologia Bohemoslovaca, suppl vol 48, S98, Prague-Czech Republic, B-10. M. Naziroglu, M. Cay, B. Ustundag. Protective role of intraperitoneally adminstered vitamin E and selenium on the levels of lipid peroxidation in the blood, liver and muscle of rats made diabetic with streptozotocin. Physiological Research, Formerly Phsyiologia Bohemoslovaca, supp1 vol 48, S99, Prague-Czech Republic, B-1l. Ustundag B. Dogan Y., Yılmaz E. The levels of plasnmma homocysteine in children with insulin dependen tdiabetes mellitus. 15 th IFCC-FESCC European Congresss of Clinical Chemnistry and Laboratory medicine., 22 nd National Congress of the Spanish Society of Clinical Biochemistry and Molecular Biology. Barcelona,SPAĐN- 1-5 June Poster Number T-103. B-12. Ustundag B. Dogan Y., Yılmaz E., Düzgün S. Relationships between serum leptin, lipoprotein (a) and insulin like growth factor-1 in newly diagnosed insulin dependent diabetes mellitus. 15 th IFCC-FESCC European Congresss of Clinical Chemnistry and Laboratory medicine., 22 nd National Congress of the Spanish Society of Clinical Biochemistry and Molecular Biology. Barcelona,SPAĐN- 1-5 June Poster Number T-104.
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