Infection meets Immunity

Transcription

1 Utrecht Summer School course Infection meets Immunity July 30 August 10, 2012 Infection & Immunity Center Utrecht Heidelberglaan 100 H Tel:

2 Contents General information... 3 Programme... 5 Speaker contact information Route description Route description venues... 18

3 General information Target group The program is intended for master students and starting PhD-students. It is necessary to have a course certificate in Immunology and/or Microbiology or courses with similar content. Course aim Utrecht University has a strong history in research Infection and Immunity. It is home to some world-wide expert research teams in this area. The aim of this course is to familiarize you in depth with the scientific knowledge in the field of Infection and Immunity. After this course students will be able to relate immunological principles and clinical consequences and will have knowledge about bacterial and viral related diseases. Especially on those areas where infection meets immunity Reading Immunology: Kuby et al. 6th edition, 2006, W.H. Freeman & Company Alberts - Molecular Biology of the Cell, 4th or 5th edition Schaechter s Mechanisms of Microbial Disease Webinars Feedback We value your opinion and try to improve our course every year. In your binder you will find an evaluation form. Please fill out this form during the course. Breaks The Infection & Immunity Center Utrecht will provide you with coffee and tea during the coffee breaks. The University Hospital () will provide you with a lunch card. You can use this card in the staff canteen at the. Internet access The studielandschap (2nd and 3rd floors of the Hijmans vd Bergh) has public computers. You should be able to access through wireless too in the Hijmans van den Bergh building and the foyer of the University Hospital. Information on wireless can be found here: Most of the information is in

4 Dutch, but the part about wireless has an English version. Also, the University Library has computers and wireless access. Secretary Karlijn Visser, room H Phone: +31 (0) ,

5 Monday 30 July 2012 Registration International Office, Introduction Microbiology Jos van Putten Lunch provided by Infection and Immunity Center Utrecht Immunology Frits Gmelig Meyling Utrecht Summer School: Scavenger hunt Utrecht & Welcome dinner

6 Tuesday 31 July 2012 Tumor Immunology Tumor immune surveillance and Immune escape Niels Bovenschen Dedicated animal models for tumor immunotherapy Anton Martens Lunch Break Tumor immunotherapy with innate immune cells Jurgen Kuball Tumor immunotherapy with allo-sct and donor T cells Tuna Mutis Welcome Meeting Point: International Office!!!! hrs Utrecht Summer School: drinks

7 Wednesday 1 August 2012 Bacterial Pathogenesis: The case of Staphylococcus aureus Intro Jos van Strijp Complement and complement evasion Suzan Rooijakkers Break Phagocytes and Phagocytosis Evasion Kok van Kessel Lunch Break Interactive Session: Bacterial evasion strategies Carla de Haas and Jovanka Bestebroer Interactive Session: Quorum Sensing, Intracellular Reindert Nijland and Survival and Biofilms and Jos van Strijp Closing Remarks Jos van Strijp Traditional (indoor) picnic

8 Thursday 2 August 2012 The tolerant Immune System What is tolerance? Willem van Eden How the antigen processing pathway regulates CD8 Alice Sijts T cell responses to self and foreign antigens Break Utilizing regulatory T cells to fight autoimmune diseases Martijn van Herwijnen Lunch break Dead by immunity: Sepsis Interactive session Eric Hack Night Canoeing

9 Friday 3 August 2012 Extracellular Microbiology Bacterial virulence strategies Jos van Putten Break The Campylobacter problem Lieneke Bouwman Saturday 4 August, Discover Holland Day Sunday 5 August, 9.30 Visit to Rotterdam & Delft

10 Monday 6 August Autoimmunity Ruth Fritsch Break Allergy; the clinical point of view Carla Bruijnzeel-Koomen Is IgE all there is in allergy? Edward Knol Lunch Break Hygiene hypothesis; infection meets allergy? Edward Knol Utrecht Summer School: Pub Quiz & Summerschool drinks

11 Tuesday 7 August 2012 Clinical and veterinary bacteriology: diagnostics and public health Introduction and explanation of today s program Hans Kusters Antibiotic resistance: Apocalyps now or media hype? Marc Bonten Break Healthy feed healthy animals healthy food Boyd Berends Antimicrobial: the more we use, the faster we lose Els Broens Lunch Break Molecular epidemiology and population genetics in Rob Willems infectious diseases Clonal emergence of staphylococcus pseudintermedius Koen Verstappen among the Dutch dog population Break Clinical microbiological diagnostics Hans Kusters

12 Wednesday 8 August 2012 Vaccines Introduction Victor Rutten Vaccines: from trial and error to rational design Claire Boog Break Pneumococcal Vaccination Lieke Sanders Vaccination against mycobacterial infections Victor Rutten Contribution from Veterinary Medicine Lunch break Guided tour Faculty of veterinary Medicine!Venue: Androclusgebouw (Androclus building), Yalelaan 1, De Uithof, Utrecht! Meeting point at the entrance of the Building Utrecht Summer School: Traditional Dutch Picnic

13 Thursday 9 August HIV entry; a key process in viral transmission, pathogenesis Anne Wensing and eradication Immune evasion by viruses: masters of disguise Emmanuel Wiertz Break Evasion of innate and adaptive immunity by Epstein-Barr virus: Danielle Horst putting the puzzle together Tour of the medical microbiology lab with demonstrations of various state-of-the art techniques Utrecht Summer School: Night Canoeing

14 Friday 10 August International office present to collect your keys and lunch cards The great debate Certificates and evaluation

15 Speaker contact information Name Institute Boyd Berends Jovanka Bestebroer Marc Bonten Claire Boog Lieneke Bouwman Niels Bovenschen Els Broens Carla Bruijnzeel- Koomen Willem van Eden Ruth Fritsch Frits Gmelig Meyling Carla de Haas Erik Hack Martijn van Herwijnen Daniëlle Horst Kok van Kessel Veterninary Sciences Public Health Medical Microbiology National Institute for Public Health and the Environment Unit Vaccinology Veterinary Sciences Department of Infection Biology Department of Pathology Veterinary Sciences VDMC Department of Dermatology Veterinary Sciences Department of Immunology Department of Immunology Department of Immunology Department of Immunology Veterinary Sciences Department of Immunology

16 Edward Knol Jurgen Kuball Hans Kusters Anton Martens Tuna Mutis Reindert Nijland Jos van Putten Suzan Rooijakkers Victor Rutten Lieke Sanders Jos van Strijp Alice Sijts Koen Verstappen Anne Wensing Emmanuel Wiertz Rob Willems Marc Wösten Department of Dermatology Department of Haematology Department of Immunology Department of Clinical Chemistry and Haematology Veterinary Sciences Department of Infection Biology Veterinary Sciences Department of Immunology Department of Immunology Veterinary Sciences Department of Immunology Veterinary Sciences Department of Infection Biology Department Microbiology Veterinary Sciences Department of Infection Biology nl

17 Route description Public transportation The UMC is well accessible by public transportation. From the central train station (Utrecht CS) busses 11 and 12 go to the uithof and the. For bus 12 the UMC is the last bus stop. Bus 11 stops at the UMC, but it is not the last stop. Parking You can park your car at the parking space of the. From Den Haag/Rotterdam: (A12) follow Utrecht. At the junction Lunette, go in the direction Amersfoort (A27). Follow the signs H UMC. After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated. From Breda/Den Bosch (A27) or Arnhem (A12) At the junction Lunette, go in the direction Hilversum (A27) At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit De Uithof / UMC After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated. From Amersfoort (A28) Follow Utrecht and leave the highway at exit De Uithof / UMC After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated. From Hilversum (A27) At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit De Uithof / UMC After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated. From Amsterdam (A1) Leave the A1 at exit Hilversum (A27). At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit De Uithof / UMC After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated. From Amsterdam (A2) At the junction Oudenrijn go in the direction Arnhem (A12). Follow the A27 in the direction Amersfoort. At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit De Uithof / UMC After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

18 Route description venues Hijmans van den Bergh building Room HB 2.05 Start: main entrance o Go to the left and walk until you reach the red junction. o Go to the left, you are now entering the Hijmans van den Bergh building. o There is an elevator on your right, take the elevator to the 2 nd floor. o When you exit the elevator, go left. o Room HB 2.05 is the room in front of you. Wilhelmina Children s Hospital (WKZ) Kindertheater (Children s theatre) Start: main entrance o Walk straight until you can t go any further (you ll see 2 elevators in front of you and a glass door on your right). o Take the elevator to floor -1. o When you exit the elevator, go into the tunnel on your left. o Walk until you exit the tunnel o Go into the corridor on your left and walk until you reach the elevators and stairs. o Go to floor 0, you are now in the children s hospital. o Cross the foyer and go into the corridor. o The children s theatre is about halfway down the corridor, on the left. Computer room 2 Start: main entrance o Go to the left and walk until you reach a red door on your right. o Go through these doors and walk to the back of the room. o Go into the corridor on the right (follow the signs CLZ2 ) o Computer room 2 is the last room on the right.