The International Inuit Cohort: Emergence of Chronic Diseases (Project 1.5) Eric Dewailly, Grace Egeland, Kue Young Laval U., Mc Gill U.

Size: px
Start display at page:

Download "The International Inuit Cohort: Emergence of Chronic Diseases (Project 1.5) Eric Dewailly, Grace Egeland, Kue Young Laval U., Mc Gill U."

Transcription

1 The International Inuit Cohort: Emergence of Chronic Diseases (Project 1.5) Eric Dewailly, Grace Egeland, Kue Young Laval U., Mc Gill U., U of Toronto

2 It is better to be healthy than ill or dead. That is the beginning and the end of the only real argument for public health. It is sufficient. Geoffrey Rose Any questions?

3 Figure 8 Arctic Net Ship time Inuit Health Study Project 1.5 E. Dewailly (PL) G. Egeland (CoL) K. Young (CoL) Project 3.5 P. Ayotte (PL) L. Chan (CoL) QANUIPPITAA É. Dewailly (PL) S. Déry (PL) MSSS RRSSS CVD diseases CIHR E. Dewailly (PL) Environmental contaminants NCP E. Dewailly (PL) Studies on waterborne diseases and zoonoses Project 2.3 B. Lévesque (PL) Project W. Vincent (PL) É. Dewailly (CoL) D. Martin (NI)

4 The Inuit Diet and Health Study An International Study of the Impact of Diet on Health and Disease among the Inuit and Yupik

5 Prospective cohort The Inuit Health in Transition Cohort Study: A circumpolar study of the impacts of diet on health and disease among the Inuit and the Yupik The Inuit Health in Transition Cohort Study is a prospective study that will be repeated every 7 years In 2004 the Inuit Health in Transition study was merged with the Nunavik Health Survey (Quanuippitaa?) The cohort study results of Nunavik allows a comparison with Inuit population of Greenland, Alaska, Nunavut and Siberia

6 Circumpolar Inuit Health Cohort: Circumpolar Inuit Health Cohort: The Qanuippitaa Survey

7 Nunavik Inuit Health Survey Photos: Isabelle Dubois

8 Study Population All permanent Nunavik residents Exception of exclusively non-inuit households and persons living full time in public institutions A total 600 Inuit households randomly chosen Respondents aged 15 and over. Total participants: 1058 (117 aged 15-17)

9 Data were collected in the 14 Nunavik communities between August and October 2004 Data were gathered onboard the Amundsen Participants were transported by barge and helicopter from the community to the ship

10

11

12 Ethics Use of video to explain the study Consent forms for the survey and the cohort

13 Data collection - questionnaires data were gathered through structured interviews with survey participants household questionnaire individual questionnaire confidential questionnaire (self-administered) 24 hour dietary recall + food consumption frequency (except pregnant women) clinical questionnaire

14 Dietary and clinical questionnaires The clinical questionnaire (18 and over) collected information on personal and family medical history (cardiovascular disease, cancer, and associated risk factors). The 24 hour dietary recall and food consumption frequency questionnaire assessed: average food, calorie, and macro- and micro-nutrient intake; the contribution of main food groups to calorie and nutrient intake; the frequency with which traditional and commercial foods are consumed on a daily, seasonal, and yearly basis.

15

16 Clinical measurements Blood pressure Height, sitting height, waist and hip Corporal impedance + weight Cardiac variability (Holter : + than 40 years old) Atherosclerosis measurement (carotid) Osteoporosis (bone density: women + 35 years old) Hearing tests (+ than 18 years old)

17 Blood analyses Cardiovascular risk factors (classical) Cholesterol total HDL-cholesterol LDL-cholesterol Triglycerides Glucose + OGTT Insulinemia New markers Oxidative markers (LDL-Ox) APO B, A1 Inflammatory markers: CRP, IL-6, TNF-a LDL phenotype

18 Some research questions Are trans fatty acids from junk food an issue? How blood lipids evolved since 1992 Is atherosclerosis prevalent among Inuit? Is obesity associated with inflammation? Are LDL particles dense (atherogenic)? Are carbohydrates and omega-3 an explosive mix for diabetes? Are omega-3 protecting Inuit against ischemic heart diseases? By which mechanisms: cardiac variability, lipids, etc.?

19 Taux mortalité coronarienne (par ) Quintiles MRFIT États-Unis Québécois non autochtones Espagne y = -2,8075x + 211,97 R 2 = 0,9573 Cris Baie-James Inuits Nunavik Japon Groenland % HUFA n-3 (des HUFA totaux) Association entre taux de mortalités coronariennes ajustés pour l âge (pour pers.) et proportions d oméga-3 dans les acides gras hautement insaturés (HUFA) totaux des tissus. Figure reproduite Lands (2003) avec permission de l auteur. %HUFAn-3 (des HUFA totaux)=(hufan-3/hufa totaux) * 100 Résultats de Lands et al BBA. (1180): Lands et al FASEB J.( 6): Dewailly E. et al Am J Clin Nutr. 76(1): Dewailly E. et al Am J Clin Nutr. 76(1): Dewailly E et al Am J Clin Nutr 74(5):

20

21 Transfats?

22 Transfatty acids (% plasma PhL) according to age Europe: 0.36 % Age groups years N Mean

23 Results:.since the 1992 s health survey (SEE ORAL PRESENTATION ML CHÂTEAU-DEGAT ET AL.) Male Female ESI92 ESI p<0.01 Male Female p< p<0.01 Male Female p<0.01 ESI92 ESI Male Female ESI92 ESI04 ESI92 ESI04 Prevalence of low HDL( 0.9 mmol/l) in % Prevalence of total cholesterol High ( 6.2 mmol/l) in % Prevalence of abnormally high level ( 2.3 mmol/l) of triglycerides in % Prevalence of high LDL ( 3.4 mmol/l) in %

24 Tot Chol/HDL according to Body Mass Index Body Mass Index (kg/m 2 ) N Mean IC Normal:<= Overweight: Obesity: Severe Obesity:>=

25 Fasting glucose (mmol/l) according to Body Mass Index Body Mass Index (kg/m2) N Mean IC Normal:<= Overweight: Obesity: Severe Obesity2:>=

26 Tot Chol/HDL according to fasting glucose Fasting glucose (mmol/l) N Mean IC Normal:< Prediabetes: Diabetes: >=

27 Triglycerides (mmol/l) according to Body Mass Index Body mass index (kg/m2) N Mean IC Normal:<= Overweight: Obesity: Severe Obesity >=

28 Triglycerides (mmol/l) according to fasting glucose Fasting glucose mmol/l N Mean IC Normal:< Prediabete: Diabete: >=

29 HDL (mmol/l) according to age groups Age groups(years) N Mean IC Total

30 Tot Chol/HDL according to fasting glucose Fasting glucose (mmol/l) N Mean IC Normal:< Prediabete: Diabete: >=

31

32

33 Omega-3 (% plasma PhL) according to age Age groups years N Mean

34 Glycemia and omega-3

35 Omega-3 (% plasma PhL) according to diabetes status Fasting glucose N Mean Normal:< 5.6 mmol Prediabetes: Diabetes: >=

36 Omega-3 (% PhL) according to Body Mass Index Body mass index N Mean Normal:<= Overweight: Obesity: Severe Obesity2:>=

37 IMT measure Early diagnosis of atherosclerosis Non invasive Portable Carotid Ultrasound (E Lonn Mc Master)

38 Intima - Medial Thickness (IMT) 0.70mm 1.15mm 2.43mm

39 The Role of Carotid IMT in Predicting Coronary Events and Stroke The Cardiovascular Health Study 5858 subjects 65 yrs 4476 subjects - no CVD at baseline Follow-up: 6.2 years O Leary et al. NEJM, 1999;340: Unadjusted cumulative event-free rates for the combined endpoint MI and stroke by quintiles of IMT

40 Mean maximum carotid artery intimal medial thickness (mm) in the entire population and by gender according to various determinants Overall Women Men Mean SD Mean SD Mean SD BMI Age years years years Fasting glucose Normal < At risk Diabetes >=7.0*

41 Fasting glucose (mmol/l) according to IMT IMT(mm) N Mean IC Q1: Q2: Q3: Q4:

42 Omega-3 (% PhL) according to IMT IMT(mm) N Mean Q1: Q2: Q3: Q4:

43 IL-6 (pg/ml) according to IMT IMT (mm) N Mean IC Q1: Q2: Q3: Q4:

44

45 LDL size (Ǻ) according to IMT IMT(mm) N Mean IC Q1: Q2: Q3: Q4:

46 Some prelminary conclusion CVD classical risk factors including diabetes are still low compared to other aboriginal groups. Obesity has increased particularly abdominal obesity among women Transfats are high among yound adults Atherosclerosis is present but moderate, inflammation too. Electrical protection by omega- 3?

47 Is cardiac variability the 2-h duration Predictor of IHD prognosis key? Improved by n-3 FA

48 Bikkina et al., 1998

49 Film with Glacialis Media com. Talk shows Posters Web site Reports Communications

50

51 Nasivvik Onboard Training ArcticNet International Training Fund $40K per year to provide access to training Schools

52 Thanks to all collaborators The Qanuippitaa Staff Institut National de la Santé Publique Staff CRCHUL Staff Nunavik Health staff Students: Beatriz Valera (MSc), Dre Émilie Counil (Post Doc), Dre Ludivine Château- Degat (Post Doc), Françoise Proust (PhD) Dr P Julien Dr Dr Benoit Lamarche Dr Jean Bergeron Dr Paul Poirier Dr Eva Lonn Dr Katherine Cianflone Dr Jean Marie Ékoé

53 ArcticNet, IRIS J. of Peperoni Res. Int. J. of Garlic Am. J. Mozz.

54 Greenland:Status for data collection

55

56 Status for data collection Community Target Result Remaining Nanortalik bygder Qaqortoq Narsaq Nuuk Nuuk bygder Maniitsoq Maniitsoq bygder Aasiaat Qasigiannguit Ilulissat bygder Upernavik Upernavik bygder Tasiilaq Total

57 IHT Greenland - Fall 2006 visit to villages Community Sample Result Participation rate Upernavik Kullorsuaq Innaarsuit Aappilattoq All IHT

58

59

60

61

62 Thank you

Body Composition & Longevity. Ohan Karatoprak, MD, AAFP Clinical Assistant Professor, UMDNJ

Body Composition & Longevity. Ohan Karatoprak, MD, AAFP Clinical Assistant Professor, UMDNJ Body Composition & Longevity Ohan Karatoprak, MD, AAFP Clinical Assistant Professor, UMDNJ LONGEVITY Genetic 25% Environmental Lifestyle Stress 75% BMI >30 OBESE 25-30 OVERWEIGHT 18-25 NORMAL WEIGHT 18

More information

Hôpitaux Universitaires de Genève Lipides, métabolisme des hydrates de carbonne et maladies cardio-vasculaires

Hôpitaux Universitaires de Genève Lipides, métabolisme des hydrates de carbonne et maladies cardio-vasculaires Hôpitaux Universitaires de Genève Lipides, métabolisme des hydrates de carbonne et maladies cardio-vasculaires Prof. J. Philippe Effect of estrogens on glucose metabolism : Fasting Glucose, HbA1c and C-Peptide

More information

Article. Heart health and cholesterol levels of Canadians, 2007 to 2009. Component of Statistics Canada Catalogue no. 82-625-X Health Fact Sheets

Article. Heart health and cholesterol levels of Canadians, 2007 to 2009. Component of Statistics Canada Catalogue no. 82-625-X Health Fact Sheets Component of Statistics Canada Catalogue no. 82-625-X Health Fact Sheets Article Heart health and cholesterol levels of Canadians, 2007 to 2009 March How to obtain more information For information about

More information

YOUR GUIDE TO. Lowering The Risk of Heart Attack and Stroke

YOUR GUIDE TO. Lowering The Risk of Heart Attack and Stroke YOUR GUIDE TO Lowering The Risk of Heart Attack and Stroke The Mercy Health Heart Institute team is focused on helping you keep your heart healthy. As part of this effort, it s important for you to know

More information

Prevention of Cardiovascular Disease in Children with Diabetes

Prevention of Cardiovascular Disease in Children with Diabetes Prevention of Cardiovascular Disease in Children with Diabetes Stephen R. Daniels, MD, PhD Department of Pediatrics University of Colorado School of Medicine The Children s Hospital Anschutz Medical Campus

More information

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD STROKE AND HEART DISEASE IS THERE A LINK BEYOND RISK FACTORS? D AN IE L T. L AC K L AN D DISCLOSURES Member of NHLBI Risk Assessment Workgroup RISK ASSESSMENT Count major risk factors For patients with

More information

Protein Intake in Potentially Insulin Resistant Adults: Impact on Glycemic and Lipoprotein Profiles - NPB #01-075

Protein Intake in Potentially Insulin Resistant Adults: Impact on Glycemic and Lipoprotein Profiles - NPB #01-075 Title: Protein Intake in Potentially Insulin Resistant Adults: Impact on Glycemic and Lipoprotein Profiles - NPB #01-075 Investigator: Institution: Gail Gates, PhD, RD/LD Oklahoma State University Date

More information

Metabolic Syndrome Overview: Easy Living, Bitter Harvest. Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007

Metabolic Syndrome Overview: Easy Living, Bitter Harvest. Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007 Metabolic Syndrome Overview: Easy Living, Bitter Harvest Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007 Evolution of Metabolic Syndrome 1923: Kylin describes clustering

More information

Blood Pressure Weight BMI. Numbers KNOW YOUR LDL/HDL. Triglycerides. holesterol

Blood Pressure Weight BMI. Numbers KNOW YOUR LDL/HDL. Triglycerides. holesterol Blood Pressure Weight BMI Blood Sugar KNOW YOUR holesterol LDLHDL Numbers Triglycerides Your health truly is the most important thing in your life. Knowing your medical history and getting annual checkups

More information

REACH Risk Evaluation to Achieve Cardiovascular Health

REACH Risk Evaluation to Achieve Cardiovascular Health Dyslipidemia and obesity History: A 13-year-old girl is seen for a routine clinic follow-up visit. She has been previously healthy, but her growth curve shows increasing body mass index (BMI) percentiles

More information

An International Atherosclerosis Society Position Paper: Global Recommendations for the Management of Dyslipidemia

An International Atherosclerosis Society Position Paper: Global Recommendations for the Management of Dyslipidemia An International Atherosclerosis Society Position Paper: Global Recommendations for the Management of Dyslipidemia Introduction Executive Summary The International Atherosclerosis Society (IAS) here updates

More information

Diabetes and Heart Disease

Diabetes and Heart Disease Diabetes and Heart Disease Diabetes and Heart Disease According to the American Heart Association, diabetes is one of the six major risk factors of cardiovascular disease. Affecting more than 7% of the

More information

Improving cardiometabolic health in Major Mental Illness

Improving cardiometabolic health in Major Mental Illness Improving cardiometabolic health in Major Mental Illness Dr. Adrian Heald Consultant in Endocrinology and Diabetes Leighton Hospital, Crewe and Macclesfield Research Fellow, Manchester University Metabolic

More information

Health Passport. Your Journey to Wellness. Health Fair ID#

Health Passport. Your Journey to Wellness. Health Fair ID# Health Passport Your Journey to Wellness Health Fair ID# Body Mass Index What is BMI? Your body mass index, or BMI, shows the amount of fat in your body. BMI is calculated using height, weight, and waist

More information

Sedentarity and Exercise in the Canadian Population. Angelo Tremblay Division of kinesiology

Sedentarity and Exercise in the Canadian Population. Angelo Tremblay Division of kinesiology Sedentarity and Exercise in the Canadian Population Angelo Tremblay Division of kinesiology Disclosure of Potential Conflicts of Interest Évolution de la pratique d activité physique des adultes canadiens

More information

Margarines and Heart Disease. Do they protect?

Margarines and Heart Disease. Do they protect? Margarines and Heart Disease Do they protect? Heart disease Several studies, including our own link margarine consumption with heart disease. Probably related to trans fatty acids elevate LDL cholesterol

More information

Know Your Resistance A Guide to Better Health

Know Your Resistance A Guide to Better Health Know Your Resistance A Guide to Better Health This material is copyrighted by Bayer HealthCare LLC and is intended solely for use in the Know Your Series educational programs supported by Bayer HealthCare

More information

Ernährungsbedingte Risikofaktoren für das metabolische Syndrom bei übergewichtigen Kindern

Ernährungsbedingte Risikofaktoren für das metabolische Syndrom bei übergewichtigen Kindern Ernährungsbedingte Risikofaktoren für das metabolische Syndrom bei übergewichtigen Kindern Dr. Isabelle Aeberli Human Nutrition Laboratory, ETH Zurich Clinic for Endocrinology Diabetes and Clinical Nutrition,

More information

Expert Commentary. A response to the recent JAMA meta analysis on omega 3 supplementation and cardiovascular events

Expert Commentary. A response to the recent JAMA meta analysis on omega 3 supplementation and cardiovascular events Expert Commentary A response to the recent JAMA meta analysis on omega 3 supplementation and cardiovascular events Dr. Bruce J. Holub, Ph.D., Professor Emeritus, University of Guelph Expert Commentary:

More information

TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION. Robert Dobbins, M.D. Ph.D.

TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION. Robert Dobbins, M.D. Ph.D. TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION Robert Dobbins, M.D. Ph.D. Learning Objectives Recognize current trends in the prevalence of type 2 diabetes. Learn differences between type 1 and type

More information

Antiretroviral treatment is Associated with increased Arterial Stiffness in Sub- Saharan African HIV-1 Infected Patients: A cross- Sectional Study

Antiretroviral treatment is Associated with increased Arterial Stiffness in Sub- Saharan African HIV-1 Infected Patients: A cross- Sectional Study Antiretroviral treatment is Associated with increased Arterial Stiffness in Sub- Saharan African HIV-1 Infected Patients: A cross- Sectional Study Titus F. Msoka Supervisors Marceline van Furth Yvo Smulders

More information

Diabetes and Stroke. Understanding the connection between diabetes and the increased risk of stroke

Diabetes and Stroke. Understanding the connection between diabetes and the increased risk of stroke Diabetes and Stroke Understanding the connection between diabetes and the increased risk of stroke Make the Connection Almost 26 million people in the U.S. roughly 8 percent of the population have diabetes.

More information

Clinical Research on Lifestyle Interventions to Treat Obesity and Asthma in Primary Care Jun Ma, M.D., Ph.D.

Clinical Research on Lifestyle Interventions to Treat Obesity and Asthma in Primary Care Jun Ma, M.D., Ph.D. Clinical Research on Lifestyle Interventions to Treat Obesity and Asthma in Primary Care Jun Ma, M.D., Ph.D. Associate Investigator Palo Alto Medical Foundation Research Institute Consulting Assistant

More information

Kansas Behavioral Health Risk Bulletin

Kansas Behavioral Health Risk Bulletin Kansas Behavioral Health Risk Bulletin Kansas Department of Health and Environment November 7, 1995 Bureau of Chronic Disease and Health Promotion Vol. 1 No. 12 Diabetes Mellitus in Kansas Diabetes mellitus

More information

Freiburg Study. The other 24 subjects had healthy markers closer to what would be considered ideal.

Freiburg Study. The other 24 subjects had healthy markers closer to what would be considered ideal. Freiburg Study The Freiburg Study was conducted with 48 healthy human subjects of various ages. None of the test subjects had been diagnosed with any disease prior to the study. None were taking any type

More information

Cardiovascular disease physiology. Linda Lowe-Krentz Bioscience in the 21 st Century October 14, 2011

Cardiovascular disease physiology. Linda Lowe-Krentz Bioscience in the 21 st Century October 14, 2011 Cardiovascular disease physiology Linda Lowe-Krentz Bioscience in the 21 st Century October 14, 2011 Content Introduction The number 1 killer in America Some statistics Recommendations The disease process

More information

Let s talk about: Stroke

Let s talk about: Stroke Let s talk about: Stroke February 20 th 2013 Laura Wilson Christine Stables Questions 1. Why is knowing about stroke important? 2. What exactly is a stroke and what are the symptoms? 3. What should I do

More information

DIABETES YOUR GUIDE TO

DIABETES YOUR GUIDE TO YOUR GUIDE TO DIABETES b What is diabetes? b Type 2 diabetes prevention b Prevention checklist b Living with diabetes b Complications b Terms to know b Resources To promote and protect the health of Canadians

More information

Getting Off the Chronic Disease Merry-Go-Round: What s the Weight of the Research?

Getting Off the Chronic Disease Merry-Go-Round: What s the Weight of the Research? Getting Off the Chronic Disease Merry-Go-Round: What s the Weight of the Research? Jody Dushay, MD MMSc Beth Israel Deaconess Medical Center Boston, MA Session 445 No disclosures Disclosure Jody Dushay,

More information

Triglycerides: Frequently Asked Questions

Triglycerides: Frequently Asked Questions Triglycerides: Frequently Asked Questions Why are triglycerides important? The amount of triglycerides (or blood fats) in blood are one important barometer of metabolic health; high levels are associated

More information

Professor Tom Sanders

Professor Tom Sanders Nutritional aspects of chocolate confectionery fats Professor Tom Sanders Nutritional Sciences Division King s College London Doctors reject chocolate tax Published: Thursday, 12 March 2009, 10:48AM Doctors

More information

HEALTH MANAGEMENT PLAN PROGRAMME

HEALTH MANAGEMENT PLAN PROGRAMME HEALTH MANAGEMENT PLAN PROGRAMME Medical Controls for Referees and Candidates The FIVB believes that Referees and Referees Candidates health is very important therefore in accordance with the Medical and

More information

WHO STEPwise approach to chronic disease risk factor surveillance (STEPS)

WHO STEPwise approach to chronic disease risk factor surveillance (STEPS) WHO STEPwise approach to chronic disease risk factor surveillance (STEPS) Promotion of Fruits and Vegetables for Health African Regional Workshop for Anglophone Countries Mount Meru Hotel, Arusha, Tanzania

More information

Appendix: Description of the DIETRON model

Appendix: Description of the DIETRON model Appendix: Description of the DIETRON model Much of the description of the DIETRON model that appears in this appendix is taken from an earlier publication outlining the development of the model (Scarborough

More information

Medicare s Preventive Care Services. Manage Your Chronic Kidney Disease (CKD stages 3-4) with Diet

Medicare s Preventive Care Services. Manage Your Chronic Kidney Disease (CKD stages 3-4) with Diet s Preventive Care Services Manage Your Chronic Kidney Disease (CKD stages 3-4) with Diet What do the kidneys do? Your kidneys have important jobs to do in your body. Two of the kidneys most important jobs

More information

Collaborating on Elementary Nutrition Education

Collaborating on Elementary Nutrition Education Collaborating on Elementary Nutrition Education Arthur S. Agatston, MD, FACC University of Miami Miller School of Medicine; Agatston Research Foundation Co-Principal Investigator Heart disease mortality

More information

Diabetes Prevention in Latinos

Diabetes Prevention in Latinos Diabetes Prevention in Latinos Matthew O Brien, MD, MSc Assistant Professor of Medicine and Public Health Northwestern Feinberg School of Medicine Institute for Public Health and Medicine October 17, 2013

More information

Design and principal results

Design and principal results International Task Force for Prevention Of Coronary Heart Disease Coronary heart disease and stroke: Risk factors and global risk Slide Kit 1 (Prospective Cardiovascular Münster Heart Study) Design and

More information

All About Body Mass Index (BMI)

All About Body Mass Index (BMI) All About Body Mass Index for Adults What is BMI? Body Mass Index is a number calculated from a person's weight and height. BMI is a fairly reliable indicator of body fat for most people. BMI does not

More information

Η δίαιτα στην πρόληψη του αγγειακού εγκεφαλικού επεισοδίου

Η δίαιτα στην πρόληψη του αγγειακού εγκεφαλικού επεισοδίου ΠΡΟΓΡΑΜΜΑ ΜΕΤΑΠΤΥΧΙΑΚΩΝ ΣΠΟΥΔΩΝ «Η ΔΙΑΤΡΟΦΗ ΣΤΗΝ ΥΓΕΙΑ ΚΑΙ ΣΤΗ ΝΟΣΟ» Η δίαιτα στην πρόληψη του αγγειακού εγκεφαλικού επεισοδίου Γεώργιος Ντάιος Παθολογική Κλινική Πανεπιστημίου Θεσσαλίας Stroke Statistics

More information

3.5% 3.0% 3.0% 2.4% Prevalence 2.0% 1.5% 1.0% 0.5% 0.0%

3.5% 3.0% 3.0% 2.4% Prevalence 2.0% 1.5% 1.0% 0.5% 0.0% S What is Heart Failure? 1,2,3 Heart failure, sometimes called congestive heart failure, develops over many years and results when the heart muscle struggles to supply the required oxygen-rich blood to

More information

A Passage to India: Establishing a Cardiac Rehabilitation program in India s south-east

A Passage to India: Establishing a Cardiac Rehabilitation program in India s south-east A Passage to India: Establishing a Cardiac Rehabilitation program in India s south-east Kathryn Kelly Clinical Nurse Consultant, Cardiac Rehabilitation Coordinator The Royal Melbourne Hospital India 1,025,000,000

More information

Metabolic Diseases: Obesity, Hyperlipidemia, and Diabetes

Metabolic Diseases: Obesity, Hyperlipidemia, and Diabetes Metabolic Diseases: Obesity, Hyperlipidemia, and Diabetes Obesity Approximately 1 in 3 adults are overweight in the U.S. Arizona According to CDC, Arizona has highest reported percentage of adults who

More information

Do You Know the Health Risks of Being Overweight?

Do You Know the Health Risks of Being Overweight? Do You Know the Health Risks of Being Overweight? U.S. Department of Health and Human Services NATIONAL INSTITUTES OF HEALTH WIN Weight-control Information Network What are the risks to my health from

More information

The Canadian Association of Cardiac

The Canadian Association of Cardiac Reinventing Cardiac Rehabilitation Outside of acute care institutions, cardiovascular disease is a chronic, inflammatory process; the reduction or elimination of recurrent acute coronary syndromes is a

More information

Introduction. Pathogenesis of type 2 diabetes

Introduction. Pathogenesis of type 2 diabetes Introduction Type 2 diabetes mellitus (t2dm) is the most prevalent form of diabetes worldwide. It is characterised by high fasting and high postprandial blood glucose concentrations (hyperglycemia). Chronic

More information

What is a Heart Attack? 1,2,3

What is a Heart Attack? 1,2,3 S What is a Heart Attack? 1,2,3 Heart attacks, otherwise known as myocardial infarctions, are caused when the blood supply to a section of the heart is suddenly disrupted. Without the oxygen supplied by

More information

Multiple comorbidities: additive and predictive of cardiovascular risk. Peter M. Nilsson Lund University University Hospital Malmö, Sweden

Multiple comorbidities: additive and predictive of cardiovascular risk. Peter M. Nilsson Lund University University Hospital Malmö, Sweden Multiple comorbidities: additive and predictive of cardiovascular risk Peter M. Nilsson Lund University University Hospital Malmö, Sweden Clinical outcomes: major complications of CVD Heart Attack/ACS

More information

4/4/2013. Mike Rizo, Pharm D, MBA, ABAAHP THE PHARMACIST OF THE FUTURE? METABOLIC SYNDROME AN INTEGRATIVE APPROACH

4/4/2013. Mike Rizo, Pharm D, MBA, ABAAHP THE PHARMACIST OF THE FUTURE? METABOLIC SYNDROME AN INTEGRATIVE APPROACH METABOLIC SYNDROME AN INTEGRATIVE APPROACH AN OPPORTUNITY FOR PHARMACISTS TO MAKE A DIFFERENCE Mike Rizo, Pharm D, MBA, ABAAHP THE EVOLUTION OF THE PHARMACIST 1920s 1960s 2000s THE PHARMACIST OF THE FUTURE?

More information

Fat myths. Myth: All fats are equal and equally bad for you. Myth: Lowering the amount of fat you eat is what matters the most.

Fat myths. Myth: All fats are equal and equally bad for you. Myth: Lowering the amount of fat you eat is what matters the most. Alexandra Palumbo Fat myths Myth: All fats are equal and equally bad for you. Myth: Lowering the amount of fat you eat is what matters the most. Myth: Fat-free means healthy. Saturated fats Trans-fats

More information

Why have new standards been developed?

Why have new standards been developed? Why have new standards been developed? Fitnessgram is unique (and widely accepted) because the fitness assessments are evaluated using criterion-referenced standards. An advantage of criterion referenced

More information

EMR Nutrition Data Set Indicators: Units of Measurement

EMR Nutrition Data Set Indicators: Units of Measurement EMR Nutrition Data Set Indicators: Units of Measurement Nutrition Indicator Unit of Measurement Comments Measured Height U.S.: inches Metric: centimeters Measured Weight U.S.: pounds Metric: kilograms

More information

Hypertension and Diabetes Status. 2011 Bangladesh Demographic and Health Survey

Hypertension and Diabetes Status. 2011 Bangladesh Demographic and Health Survey Hypertension and Diabetes Status 2011 Bangladesh Demographic and Health Survey Methodology and Sampling Total 18,000 households were selected nationwide (207 in urban and 393 in rural areas) One-third

More information

HDL Cholesterol Subfractions and the Effect of Testosterone Replacement in Hypogonadism

HDL Cholesterol Subfractions and the Effect of Testosterone Replacement in Hypogonadism HDL Cholesterol Subfractions and the Effect of Testosterone Replacement in Hypogonadism E. Bolu 1, A. Sonmez 1, S. Tapan 2, A. Taslipinar 1, A. Aydogdu 1, C. Meric 1, Y. Basaran 1, G. Uckaya 1, M. Serdar

More information

DIETARY ISSUES IN DIABETES

DIETARY ISSUES IN DIABETES DIETARY ISSUES IN DIABETES Elizabeth J Mayer Davis, PhD Department of Nutrition, Gillings School of Global Public Health Department of Medicine, School of Medicine University of North Carolina at Chapel

More information

Cohort Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University

Cohort Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

Is Insulin Effecting Your Weight Loss and Your Health?

Is Insulin Effecting Your Weight Loss and Your Health? Is Insulin Effecting Your Weight Loss and Your Health? Teressa Alexander, M.D., FACOG Women s Healthcare Associates www.rushcopley.com/whca 630-978-6886 Obesity is Epidemic in the US 2/3rds of U.S. adults

More information

Your healthcare provider has ordered a Boston Heart Cardiac Risk Assessment

Your healthcare provider has ordered a Boston Heart Cardiac Risk Assessment Your healthcare provider has ordered a Boston Heart Cardiac Risk Assessment What does that mean for you? Your healthcare provider has determined that you may be at risk for cardiovascular disease (CVD).

More information

Diabetes mellitus is a chronic condition that occurs as a result of problems with the production and/or action of insulin in the body.

Diabetes mellitus is a chronic condition that occurs as a result of problems with the production and/or action of insulin in the body. International Diabetes Federation Diabetes Background Information Diabetes mellitus is a chronic condition that occurs as a result of problems with the production and/or action of insulin in the body.

More information

Statins and Risk for Diabetes Mellitus. Background

Statins and Risk for Diabetes Mellitus. Background Statins and Risk for Diabetes Mellitus Kevin C. Maki, PhD, FNLA Midwest Center for Metabolic & Cardiovascular Research and DePaul University, Chicago, IL 1 Background In 2012 the US Food and Drug Administration

More information

MY TYPE 2 DIABETES NUMBERS

MY TYPE 2 DIABETES NUMBERS BLOOD SUGAR MANAGEMENT GUIDE MY TYPE 2 DIABETES NUMBERS Understanding and Tracking the ABCs of Type 2 Diabetes 1 BLOOD MY TYPE SUGAR 2 DIABETES MANAGEMENT ABC NUMBERS GUIDE When you have type 2 diabetes,

More information

Isagenix Clinical Research Summary Suk Cho, Ph.D., Eric Gumpricht, Ph.D., David Despain, M.Sc.

Isagenix Clinical Research Summary Suk Cho, Ph.D., Eric Gumpricht, Ph.D., David Despain, M.Sc. Isagenix Clinical Research Summary Suk Cho, Ph.D., Eric Gumpricht, Ph.D., David Despain, M.Sc. UIC study finds subjects on Isagenix products lost more body fat, lost more visceral fat, showed greater adherence,

More information

Cardiovascular Endpoints

Cardiovascular Endpoints The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University The Malmö Diet and Cancer Study CV-cohort Cardiovascular Endpoints End of follow-up: 30

More information

High Cholesterol (Dyslipidemia)

High Cholesterol (Dyslipidemia) High Cholesterol (Dyslipidemia) What is high cholesterol? Cholesterol is a type of fat that is found in every cell in the body. It is used to build healthy cells and some vital hormones. High levels of

More information

New Medicare Preventive

New Medicare Preventive New Medicare Preventive Services Screening Tests You Can Perform in the Office Charles B. Root, PhD Medicare is finally getting serious about preventive services. Until now, the limited preventive testing

More information

STRENGTH NUMBERS NATURALLY SLIM PROGRAM PAISBOA

STRENGTH NUMBERS NATURALLY SLIM PROGRAM PAISBOA STRENGTH in NUMBERS NATURALLY SLIM PROGRAM Annually, Business Officers of the 139 independent schools and colleges that comprise the health insurance consortium (PAISIG) meet with their broker, Armstrong,

More information

Main Effect of Screening for Coronary Artery Disease Using CT

Main Effect of Screening for Coronary Artery Disease Using CT Main Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High risk Patients with Diabetes: The FACTOR-64 Randomized Clinical Trial Joseph B. Muhlestein,

More information

YOUR GUIDE TO. Managing and Understanding Your Cholesterol Levels

YOUR GUIDE TO. Managing and Understanding Your Cholesterol Levels YOUR GUIDE TO Managing and Understanding Your Cholesterol Levels Our goal at the Mercy Health Heart Institute is to help you be well. Our experienced team includes cardiologists, cardiovascular surgeons,

More information

INSULIN RESISTANCE AND COMPENSATORY HYPERINSULINEMIA: THE LINCHPIN BETWEEN OBESITY AND CARDIOVASCULAR DISEASE

INSULIN RESISTANCE AND COMPENSATORY HYPERINSULINEMIA: THE LINCHPIN BETWEEN OBESITY AND CARDIOVASCULAR DISEASE May 2008 (Vol. 1, Issue 2, pages 4-10) INSULIN RESISTANCE AND COMPENSATORY HYPERINSULINEMIA: THE LINCHPIN BETWEEN OBESITY AND CARDIOVASCULAR DISEASE By Gerald M. Reaven, MD, Division of Cardiovascular

More information

DIET AND EXERCISE STRATEGIES FOR WEIGHT LOSS AND WEIGHT MAINTENANCE

DIET AND EXERCISE STRATEGIES FOR WEIGHT LOSS AND WEIGHT MAINTENANCE DIET AND EXERCISE STRATEGIES FOR WEIGHT LOSS AND WEIGHT MAINTENANCE 40 yo woman, BMI 36. Motivated to begin diet therapy. Which of the following is contraindicated: Robert B. Baron MD MS Professor and

More information

An Overview and Guide to Healthy Living with Type 2 Diabetes

An Overview and Guide to Healthy Living with Type 2 Diabetes MEETING YOUR GOALS An Overview and Guide to Healthy Living with Type 2 Diabetes MEETING YOUR GOALS This brochure was designed to help you understand the health goals to live a healthy lifestyle with type

More information

TERMS FOR UNDERSTANDING YOUR TYPE 2 DIABETES. Definitions for Common Terms Related to Type 2 Diabetes

TERMS FOR UNDERSTANDING YOUR TYPE 2 DIABETES. Definitions for Common Terms Related to Type 2 Diabetes TERMS FOR UNDERSTANDING YOUR TYPE 2 DIABETES Definitions for Common Terms Related to Type 2 Diabetes TYPE 2 DIABETES AND BLOOD SUGAR 1-3 This list of terms may help you beter understand type 2 diabetes,

More information

A HEALTHIER. The District s Clinic will be hosting. free flu shots and no cost or low-cost wellness screenings

A HEALTHIER. The District s Clinic will be hosting. free flu shots and no cost or low-cost wellness screenings A HEALTHIER The District s Clinic will be hosting free flu shots and no cost or low-cost wellness screenings at various District locations in November! Employees are encouraged to take advantage of this

More information

The Prevalence and Determinants of Undiagnosed and Diagnosed Type 2 Diabetes in Middle-Aged Irish Adults

The Prevalence and Determinants of Undiagnosed and Diagnosed Type 2 Diabetes in Middle-Aged Irish Adults The Prevalence and Determinants of Undiagnosed and Diagnosed Type 2 Diabetes in Middle-Aged Irish Adults Seán R. Millar, Jennifer M. O Connor, Claire M. Buckley, Patricia M. Kearney, Ivan J. Perry Email:

More information

HEART DISEASE & FIREFIGHTERS

HEART DISEASE & FIREFIGHTERS 1 HEART DISEASE & FIREFIGHTERS John Hofman CSCS, MS. 2 www.firefighterfitnessonline.com 3 1 Who Am I? 4 By the Numbers Heart Attacks continue to be the leading cause of death among firefighters 2011 -

More information

Creating a culture of wellbeing in

Creating a culture of wellbeing in Health and Wellness Program Creating a culture of wellbeing in the workplace. kl TRENCH CORPORATE HEALTH PROGRAMS 16 Yrs experience Remote and CBD 1000 employees THE AUSTRALIAN WORKPLACE 1/3 of

More information

Primary Care Guidance Program: Non-Alcohol related Fatty Liver Disease (NAFLD) Guidance on Management in Primary Care

Primary Care Guidance Program: Non-Alcohol related Fatty Liver Disease (NAFLD) Guidance on Management in Primary Care Primary Care Guidance Program: Non-Alcohol related Fatty Liver Disease (NAFLD) Guidance on Management in Primary Care This advice has been developed to help GPs with shared care of patients with Non- Alcohol

More information

PASSPORT TO WOMEN S HEALTH

PASSPORT TO WOMEN S HEALTH PASSPORT TO WOMEN S HEALTH Introduction W omen are extraordinary. Daughters, sisters, mothers, aunts, cousins, friends, wives. Saint John s Health Center recognizes the importance of women and that women

More information

Obesity in the United States Workforce. Findings from the National Health and Nutrition Examination Surveys (NHANES) III and 1999-2000

Obesity in the United States Workforce. Findings from the National Health and Nutrition Examination Surveys (NHANES) III and 1999-2000 P F I Z E R F A C T S Obesity in the United States Workforce Findings from the National Health and Nutrition Examination Surveys (NHANES) III and 1999-2000 p p Obesity in The United States Workforce One

More information

Blood clot in atheroma. help make vitamin D and hormones, like oestrogen and testosterone, in your body.

Blood clot in atheroma. help make vitamin D and hormones, like oestrogen and testosterone, in your body. CHOLESTEROL This factsheet explains what cholesterol is and why too much cholesterol in your blood is harmful. It also provides information regarding cholesterol testing and tips to help reduce your blood

More information

Marilyn Borkgren-Okonek, APN, CCNS, RN, MS Suburban Lung Associates, S.C. Elk Grove Village, IL

Marilyn Borkgren-Okonek, APN, CCNS, RN, MS Suburban Lung Associates, S.C. Elk Grove Village, IL Marilyn Borkgren-Okonek, APN, CCNS, RN, MS Suburban Lung Associates, S.C. Elk Grove Village, IL www.goldcopd.com GLOBAL INITIATIVE FOR CHRONIC OBSTRUCTIVE LUNG DISEASE GLOBAL STRATEGY FOR DIAGNOSIS, MANAGEMENT

More information

Antipsychotic Medications and the Risk of Diabetes and Cardiovascular Disease

Antipsychotic Medications and the Risk of Diabetes and Cardiovascular Disease Antipsychotic Medications and the Risk of Diabetes and Cardiovascular Disease Patient Tool #1 Understanding Diabetes and Psychiatric Illness: A Guide for Individuals, Families, and Caregivers Type 2 Diabetes,

More information

Adult Weight Management Training Summary

Adult Weight Management Training Summary Adult Weight Management Training Summary The Commission on Dietetic Registration, the credentialing agency for the Academy of Nutrition and Dietetics Marilyn Holmes, MS, RDN, LDN About This Presentation

More information

Sinclair Community College, Division of Allied Health Technologies

Sinclair Community College, Division of Allied Health Technologies Sinclair Community College, Division of Allied Health Technologies Health Promotion for Community Health Workers Cardiovascular disease, stroke, and cancer Class #5 High Blood Cholesterol (date) Course

More information

Cardiovascular Endpoints

Cardiovascular Endpoints The Malmö Diet and Cancer Study Department of Clinical Sciences Malmö University Hospital Lund University The Malmö Diet and Cancer Study CV-cohort Cardiovascular Endpoints End of follow-up: 31 Dec * Report:

More information

Dietary Composition for Weight Loss and Weight Loss Maintenance

Dietary Composition for Weight Loss and Weight Loss Maintenance Dietary Composition for Weight Loss and Weight Loss Maintenance Bridget M. Hron, MD Instructor in Pediatrics, Harvard Medical School Staff Physician in Gastroenterology & Nutrition and New Balance Foundation

More information

Emory Healthcare Heart Disease Prevention Live Chat (2/21/2011) Transcript

Emory Healthcare Heart Disease Prevention Live Chat (2/21/2011) Transcript Emory Healthcare Heart Disease Prevention Live Chat (2/21/2011) Transcript [admin] We want to thank Dr. Sperling for joining us for an interactive online Q & A web chat on the topic of heart disease prevention.

More information

Cardiovascular Disease Risk Factors

Cardiovascular Disease Risk Factors Cardiovascular Disease Risk Factors Risk factors are traits and life-style habits that increase a person's chances of having coronary artery and vascular disease. Some risk factors cannot be changed or

More information

Psoriasis Co-morbidities: Changing Clinical Practice. Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology. Psoriatic Arthritis

Psoriasis Co-morbidities: Changing Clinical Practice. Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology. Psoriatic Arthritis Psoriasis Co-morbidities: Changing Clinical Practice Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology Psoriatic Arthritis Psoriatic Arthritis! 11-31% of patients with psoriasis have psoriatic

More information

High Blood Cholesterol

High Blood Cholesterol National Cholesterol Education Program ATP III Guidelines At-A-Glance Quick Desk Reference 1 Step 1 2 Step 2 3 Step 3 Determine lipoprotein levels obtain complete lipoprotein profile after 9- to 12-hour

More information

A Calorie is a Calorie Or is It? 6 th Biennial Childhood Obesity Conference, June 30, 2011

A Calorie is a Calorie Or is It? 6 th Biennial Childhood Obesity Conference, June 30, 2011 A Calorie is a Calorie Or is It? 6 th Biennial Childhood Obesity Conference, June 30, 2011 Jeff S. Volek, Ph.D., R.D. Human Performance Laboratory Department of Kinesiology University of Connecticut Storrs,

More information

Effects of macronutrients on insulin resistance and insulin requirements

Effects of macronutrients on insulin resistance and insulin requirements Effects of macronutrients on insulin resistance and insulin requirements Dr Duane Mellor RD Assistant Professor in Dietetics, The University of Nottingham, UK Outline of Discussion Issues of determining

More information

METABOLIC SYNDROME IN A CORRECTIONS POPULATION TREATED WITH ANTIPSYCHOTICS

METABOLIC SYNDROME IN A CORRECTIONS POPULATION TREATED WITH ANTIPSYCHOTICS METABOLIC SYNDROME IN A CORRECTIONS POPULATION TREATED WITH ANTIPSYCHOTICS Andrew M. Cislo, PhD Megan J. Ehret, PharmD, MS, BCPP Robert L. Trestman, MD, PhD Kirsten Shea, MBA www.uchc.edu Background Metabolic

More information

Burden of Obesity, Diabetes and Heart Disease in New Hampshire, 2013 Update

Burden of Obesity, Diabetes and Heart Disease in New Hampshire, 2013 Update Burden of Obesity, Diabetes and Heart Disease in New Hampshire, 2013 Update Background Overweight and obesity have greatly increased among all age groups and regardless of income and education. Contributing

More information

Listen to your heart: Good Cardiovascular Health for Life

Listen to your heart: Good Cardiovascular Health for Life Listen to your heart: Good Cardiovascular Health for Life Luis R. Castellanos MD, MPH Assistant Clinical Professor of Medicine University of California San Diego School of Medicine Sulpizio Family Cardiovascular

More information

3. HOW IS THE METABOLIC SYNDROME RELATED TO THE DYSLIPIDEMIA?

3. HOW IS THE METABOLIC SYNDROME RELATED TO THE DYSLIPIDEMIA? 3. HOW IS THE METABOLIC SYNDROME RELATED TO THE DYSLIPIDEMIA? Victor Blaton KU-Leuven and Department Clinical Chemistry, Az St Jan Av, Brugge, Belgium 1. Some historical aspects on the metabolic syndrome

More information

HEART HEALTH CONSIDERATIONS

HEART HEALTH CONSIDERATIONS HEART HEALTH CONSIDERATIONS OUTLINE An introduction to modifiable and non-modifiable factors Understanding cholesterol Understanding blood pressure Weight and shape Smoking Alcohol Physical activity Healthy

More information

PowerPoint Lecture Outlines prepared by Dr. Lana Zinger, QCC CUNY. 12a. FOCUS ON Your Risk for Diabetes. Copyright 2011 Pearson Education, Inc.

PowerPoint Lecture Outlines prepared by Dr. Lana Zinger, QCC CUNY. 12a. FOCUS ON Your Risk for Diabetes. Copyright 2011 Pearson Education, Inc. PowerPoint Lecture Outlines prepared by Dr. Lana Zinger, QCC CUNY 12a FOCUS ON Your Risk for Diabetes Your Risk for Diabetes! Since 1980,Diabetes has increased by 50 %. Diabetes has increased by 70 percent

More information

Statistics of Type 2 Diabetes

Statistics of Type 2 Diabetes Statistics of Type 2 Diabetes Of the 17 million Americans with diabetes, 90 percent to 95 percent have type 2 diabetes. Of these, half are unaware they have the disease. People with type 2 diabetes often

More information