CURRICULUM VITAE JOHN CLAUDE KRUSZ, Ph.D., MD 5446 Glen Lakes Drive, Dallas, Texas Summary

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1 CURRICULUM VITAE JOHN CLAUDE KRUSZ, Ph.D., MD 5446 Glen Lakes Drive, Dallas, Texas Summary Dr Krusz has an undergraduate degree in pharmacy (B.S.) and was a Registered Pharmacist (R. Ph.), practicing in this field part-time, until the end of his medical studies. Following undergraduate training, he completed graduate studies in neuropharmacology (Ph.D.). He then completed a 2-year post-doctoral research fellowship in geriatric neuropharmacology, receiving several academic and teaching appointments, together with consulting activity in advertising, as he completed his medical studies (MD), with specialized training in neurology. Since 1987, Dr Krusz has been in private practice in Dallas with major clinical interests in the evaluation and treatment of pain and headache disorders, and with a special focus in the field of brain injury, and neuropsychiatry/neurobehavioral disorders. He is the medical director of Anodyne Headache and PainCare, a multidisciplinary clinic in North Dallas. He has been actively engaged in clinical research projects, particularly in new uses for available medications for headache, pain, cognitive enhancement and mood. He is active in numerous organizations and, most recently was elected Vice-President of the American Board of Electroencephalography and Neurophysiology (ABEN). This organization administers specialized board exams in the field of EEG. Most recently, he has been appointed to the Board of directors of the Texas Pain Society. He is board certified in Headache Medicine and was part of the first class of certification. Dr Krusz has a strong interest in the evaluation of brain disorders using EEG and other techniques such as neuropsychological cognitive testing, combined with PET/SPECT scan techniques. He is also very interested in aggressive IV treatment of pain and headache flare-ups in the outpatient clinic setting, and has developed protocols for such treatment using new IV formulations of existing oral medications. Additional interests include novel administration technique for treating patients with botulinum toxins. JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 1

2 Personal: Born in LaCourtine, France on March 7, Citizenship: United States. Education: Medical Degree M. D. Doctor of Medicine, Buffalo School of Medicine, State University of New York at Buffalo, New York; Pharmacology and Science Degrees Ph.D. (Pharmacology), State University of New York, Downstate Medical Center, Department of Pharmacology, Brooklyn, New York B. S. Bachelor of Science in Pharmacy, St. John's University College of Pharmacy, Jamaica, New York; Language Training French Dartmouth College, Rassias Foundation Studies in French Language, Hanover, New Hampshire; 1979 Internship, Residency, and Further Studies Chief Resident, Downstate Medical Center and Kings County Hospital, Department of Neurology, Brooklyn, New York Epilepsy Mini fellowship (with Dr Kiffin Penry) at Bowman-Gray Medical School, Durham, North Carolina Resident, Baylor College of Medicine Affiliated Hospitals, Department of Neurology, Houston, Texas Resident, Downstate Medical Center and Kings County Hospital, Department of Neurology, Brooklyn, New York Intern, Baylor College of Medicine Affiliated Hospitals, Department of Internal Medicine, Houston, Texas Faculte Libre de Medecine, Lille, France - Second Year medical studies under auspices of the C.I.M.E. Program Georgetown University School of Medicine, Department of Anatomy Summer Program, Washington, D.C 1972 Vanderbilt University School of Medicine, Department of Pharmacology, Summer Program in Neuropsychopharmacology (ASPET sponsorship), Nashville, Tennessee. JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 2

3 Clinical Licenses Licensed to practice medicine in Texas and New York. (N.Y. License currently inactive) Board Certifications: UCNF Board Certification in Headache Medicine (1st group) Diplomate, American Board of Neurology and Psychiatry. American Board of Electroencephalography and Neurophysiology (Board Certification in EEG). Board Certification in Pain Management (American Academy of Pain Management). Board Certification in Quantitative Electroencephalography (American Board of Electroencephalography and Neurophysiology) Diplomate, American Board of Forensic Examiners Diplomate, American Board of Forensic Medicine Military Service: Captain; Biochemist, New York National Guard, 825th Medical Laboratory, Brooklyn, New York. Professional Positions, Appointments, and Clinical Experience: Present Private practice Neurology, Dallas, Texas. Medical Director, Anodyne Headache and PainCare Present Adjunct Faculty, Department of Psychology, Southern Methodist University Consultant, New Medico Head Injury Systems Adult ambulatory medicine physician, part-time, Brookdale Hospital Medical Center, Brooklyn, New York Medical attending physician, part-time, Kings County Hospital, Forensic Unit of G Building, Brooklyn, New York (Psychiatric Hospital) Clinical Assistant Instructor, Downstate Medical Center, Department of Neurology, Brooklyn, New York Neurology consultant, part-time, Long Island College Hospital, Brooklyn, New York Physician, part-time, MacGregor Medical Clinic, Houston, Texas. JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 3

4 Instructor, Gwynedd-Mercy College, Division of Natural Sciences, Gynedd Valley, Pennsylvania Clinical rotation (externship), Cabrini Health Center, New York City (6 weeks), Emergency Room Assistant Professor, Temple University, College of Allied Health Sciences Assistant Professor, Temple University, Department of Health Education, Philadelphia, Pennsylvania Instructor, Pennsylvania College of Podiatric Medicine, Department of Pharmacology, Philadelphia, Pennsylvania Post-Doctoral Research Fellow, Medical College of Pennsylvania, Department of Pharmacology, Philadelphia, Pennsylvania Volunteer worker, Hospital of the Medical College of Pennsylvania, Surgical and Medical Intensive Care Unit, Philadelphia, Pennsylvania Adjunct Assistant Professor, Jersey City State College Graduate School, Psychology Department, Jersey City, New Jersey Instructor, Manhattan College and the College of Mount Saint Vincent, Department of Psychology and Biology, New York City Teaching Assistant, State University of New York, Downstate Medical Center, Department of Pharmacology Volunteer work, Columbus Hospital, Emergency Room, New York City PHS Pre-Doctoral Trainee, State University of New York, Downstate Medical Center, Department of Pharmacology, Brooklyn, New York. Board and Advisory Appointments Present National Speakers Bureau, Wyeth Pharmaceuticals Present National Speakers Bureau, Eli Lilly Pharmaceuticals 2006-Present National Speakers Bureau, Acorda Pharmaceuticals Present Sleep Advisory Board, Takeda Pharmaceuticals Present National Speakers Bureau- Solstice Pharmaceuticals Present National Speakers Bureau- Sanfo Aventis Pharmaceuticals Present National Speakers Bureau- Valiant Pharmaceuticals 2005-Present National Speakers Bureau- Endo Pharmaceuticals Present Faculty Advisory Committee, Argosy University, Dallas, Texas Present Co-founder, National Deaf People s Institute JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 4

5 2001- Present Advisory Board, UCB Pharma, Inc Present Associate Editor, Pain Net-on-Line Present Board Member, M.A.G.N.U.M., National Migraine Association Present North Texas Pain Society Present Committee Chair, SIG, New Therapies Present Advisory Board, Elan Pharmaceuticals Present National Speakers Bureau, Novartis Pharmaceutical Present National Speakers Bureau, Ortho-McNeil Pharmaceutical Co 1998 Present Advisory Board, Primary Care Network Present Facilitator, Migraine Education Program, Primary Care Network 1998 Present National Speakers Bureau, Pfizer, Inc Present Migraine Advisory Board, Zeneca Pharmaceuticals Present Migraine Advisory Board, Merck and Co., Inc Present Headache Advisory Board, Glaxo-SmithKline Inc Examiner, Allied Medical Consultants Texas Brain Injury Association, Board of Directors Examiner, Neurology Board Examinations for Residents and Fellows, University of Texas Southwestern Medical School, Dallas Board of Directors and Clinical Director, Headway Homes of Texas National Medical Advisory Board 1994 Present Committee Chairman, Special Interest Network in Headache, American Academy of Pain Management Faculty Member, Pain Net Education, Inc Present National Speakers Bureau, GlaxoWellcome Medical Director, Inpatient Headache Unit, Dallas Rehabilitation Institute Medical Director, Nurse Finders 1992 Present Editorial Advisory Board, Journal of Pain Management (American Academy of Pain Management) Advisory Board, Kimberly Quality Care JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 5

6 Medical Director, Neurologic Studies and Treatment Foundation, Rockwall, Texas National Multiple Sclerosis Society, Professional Advisory Committee Present North Texas Chapter of National Multiple Sclerosis Society, Executive Board North Texas Society of National Multiple Sclerosis Society, Professional Advisory Committee (Chairman) Medical Advisory Board, Nautilus Corporation. Membership in Learned Societies: Dallas County Medical Society Texas Medical Association Texas Neurologic Association American Academy of Neurology American Board of Electroencephalography and Neurophysiology (Vice-President) American Association for the Advancement of Science American Headache Society International Headache Society International Cervicogenic Headache Study Group North American Cervicogenic Headache Society Serotonin Club American Medical Association New York Academy of Sciences Electroencephalography and Clinical Neurophysiology Society International Association for the Study of Pain American Academy of Pain Management American Pain Society Texas Pain Society Greater North Texas Pain Society Brain Injury Association of Texas Dallas Brain Injury Association National Brain Injury Association JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 6

7 Behavioral Neurology Society Honors: New York State Regents Scholarship Deans Honor List, 3 years, St. John's University Eli Lilly Achievement Award Phi Delta Chi Award for Extracurricular Activities 1994 Tom Dean Humanitarian Award, Brain Injury Association of Texas 1995 and re-awarded 1999 American Academy of Pain Management Attendance Award 2003 Texas Psychological Association Clinician of the Year Award 2005 Award for Innovative Research, Allergan Laboratories Research Experience: Graduate: (State University of New York, Downstate Medical Center, Department of Pharmacology) Assay of glucuronyl transferase activity in rat liver. Effects of opiates on tissue culture preparation. Studies of the effects of drugs on neuromuscular transmission in guinea pigs vas deferens. Ph.D. thesis research on "Occurrence and experimental alterations of endogenous 5- hydroxytryptamine in peripheral sympathetically-innervated organs." (Under direction of Dr. Arun Wakade, Associate Professor, Department of Pharmacology, SUNY, Downstate Medical Center). Chairman of Department was Professor Robert F Furchgott (Nobel Laureate-1998) Post-Doctoral: (Medical College of Pennsylvania, Department of Pharmacology) Evaluation of the role of taurine in various brain areas, especially the pineal gland. Development of assay system for taurine using high-pressure liquid chromatography. Investigation of the role of taurine in the proliferation of leukemia s. Clinical evaluation of endotracheal epinephrine in models of anaphylactic shock. Surgical and pharmacological studies of the mode of action of bretylium. JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 7

8 Undergraduate: (St. John's University) Behavioral correlates of acute marihuana toxicity. Gas chromatographic analysis of active principles from digitalis and belladonna species. Synthesis of polypeptides with anticholinesterase activity. Current Research: 2008 MAP0004-CL-P301 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of MAP0004 (Tempo DHE) in Adult Migraineurs for a Single Migraine Followed by Open Label Extension to 26/52 Weeks- Map 2008 A Randomized, Double-blind, Double-dummy, Placebo-controlled, Crossover Study to Evaluate the Efficacy of TREXIMA versus Butalbital-containing Combination Medications (BCM) for the Acute Treatment of Migraine when administered during the Moderate-Severe Pain Phase of the Migraine Study- GlaxoSmithKline 2007 Multi-centre, Parallel Group, Double-Blind, Placebo Controlled, Dose Ranging Study of the efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache and Open Label Extension-Minister Pharma 2007 Evaluation of the Efficacy of Naratriptan for the Prevention and Treatment of post traumatic Headache Associated with Cognitive Dysfunction- GlaxoSmithKline 2007 A Multicenter Retrospective Chart Review of Adult Patients Treated with MYOBLOC for Spasticity-Solstice 2006 Double-Blinded, placebo-controlled trial of efficacy and safety of intra-dermal botulinum toxin, type A (BOTOX ) in the relief of pain associated with carpal tunnel syndrome- Allergan 2006 A study of Combination Product (sumatriptan succinate and naproxen sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short acting Triptans (Study 1 of 2)- GlaxoSmithKline 2005 Donepezil (Aricept ) for Mild Cognitive Difficulties (MCD) After Traumatic Brain Injury (TBI)- Eisai 2005 A Randomized, Double- Blind, Placebo Controlled, Two-Period, Crossover Study to Explore Safety and Preliminary Efficacy of Oral MK-0759 in thetreatment of Post herpetic Neuralgia. - Merck JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 8

9 2005 A multicenter, randomized, double-blind, placebo-v controlled, parallel group study to evaluate the safety and efficacy of Lamotrigine mg/day compared with placebo in subjects with painful diabetic neuropathy GlaxoSmithKline NPP101982) 2005 A Randomized, Double- Blind, Placebo-Controlled, Multi-Center, Parallel- Group Study To evaluate the Efficacy and Safety of E2007 in Migraine Prophylaxis- Eisai 2005 Divalproex Sodium Extended-Release Tablets for Migraine Prophylaxis in Adolescents: An Open-Label, Long-Term Safety Study- Abbott Laboratories 2005 A Randomized, open-label, parallel design trial to compare time to response in the symptoms of anxiety to concomitant treatment with Niravam and an SSRI or SSNRI to treatment with an SSRI or SNRI a line in subjects with Generalized Anxiety Disorder or Panic Disorder- Schwarz Pharma 2005 Frovatriptan (Frova ) Perimenstrual Migraine Headache Study- ENDO Laboratories 2005 A multicenter study evaluating the efficacy and safety of Botox (Botulinum Toxin Type A) Purified Neuroxin Complex as headache Prophylaxis in Migraine Patients with 15 or more Headache Days per 4-week period in a 24 week, Double-blind, Randomized, Placebo-Controlled, Parallel-Group Phase Followed by a 32-Week Open-Label Extension Phase- Allergan 2005 Regimen of Eszopiclone Sleep Satisfaction Trial (RESST ) Sepracor 2003 Double-blind trial of botulinum toxin, type B, in headaches of cervical origin Elan Pharmaceuticals 2002 Oxcarbazepine in migraine headaches (double blind) Novartis 2002 TOPMAT MIG001 (Double-blind investigation of topiramate in migraine headaches) (Ortho-McNeil) 2002 Morphidex Study (Endo Laboratories) with ntouch Res 2001 MIND Study-Myobloc Open-label use of botulinum toxin, type B, for various disorders Elan Pharmaceuticals 2001 International Registry KIMS study Pharmacia 2001 Sumatriptan IMPRESS study Glaxo Smith Kline Co 2001 Cranial Electrotherapy Stimulation trial (double-blind) 2001 Topiramate (Double blind) study in migraine (RWJPRI) (TOMAT-MIGR001 Protocol Ortho-McNeil 2001 Zolmitriptan in High Disability Patient Care: An Early Intervention Trial (ZODIAC study) Trial # 311CIL/0111 Astra Zeneca) MAPS, MAPS II and MAPS III Studies with Rizatriptan Merck Co JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 9

10 Sumatriptan/Naratriptan migraine recurrence study (with Dr. Robert B Nett, San Antonio) (investigator-initiated study supported by Glaxo Wellcome Study with Naratriptan for migraine preference (ClinVes Migraine Headache Therapy:Imitrex tablets versus Current Non-triptan Therapy (IMPACT Study) Glaxo Wellcome Protocol #SUM Tramadol (Ultram) in low back pain - clinical trial Ortho-McNeil 1999 TARGET study - clinical trial with Lamotrigine in seizures Glaxo Wellcome 1998 Pregabalin in low back pain Phase III double blind clinical trial Parke-Davis 1998 Pregabalin in seizures- clinical trial Parke-Davis 1998 OxyContin in low back pain - clinical trial Purdue-Pharma 1997 T.R.A.I.T.S. study - clinical trial of topiramate in epilepsy Ortho-McNeil Co 1995 A.L.E.R.T. (Adjunctive Lamictal in Epilepsy and Response to Treatment) Burroughs-Wellcome 1995 Neurontin - Clinical trial Parke-Davis Co 1994 Clinical trial of felbamate in epilepsy to 1991 Evaluation of sumatriptan in migraine headaches, Phase III Clinical Trial Glaxo Laboratories. Tablet study 1994 Evaluation of sumatriptan in migraine headaches, Phase III trial (suppository form) Glaxo Laboratories Professional Publications: 2006 Krusz, JC Intravenous treatment of chronic daily headaches in the outpatient headache clinic. Current Pain Headache Reports, Feb;10(1): Minirth, F., Neal, V., Krusz, J. C., & Hopewell, C. A. The Christians guide to natural products and remedies. Nashville: Broadman and Holman Publishers Krusz, JC, Roberts, S, Thomson, J. A prospective study of cognitive enhancement with Galantamine increased over four months in patients with traumatic brain injury, J Neuropsychiatry and Clinical Neuroscience, May; 17: Krusz, JC, Hopewell, CA, Thomson, J, Roberts, S. Donepezil for cognitive enhancement after traumatic brain injury, J Neuropsychiatry and Clinical Neuroscience, May; 17: Krusz, JC, Aggressive Interventional Treatment of Intractable Headaches in the Clinic in: Clinics in Family Practice, J Unger, editor, 7:545-65, September 2004 Krusz, JC, Zonisamide in the Treatment of Headaches, Pain Practice) 2004 Krusz, JC, Tension-type Headaches: what they are and how to treat them, Primary care: Clinics in Office Practice, 31: JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 10

11 2004 Krusz, JC, Biondi, B, The convergence of migraine, chronic migraine and neuropathic pain: implications for therapy, ADIS Press, New Zealand 2004 Krusz, JC, Cagle, J, Knoderer, WR, Scott, V, Daniel, D, Levetiracetam IV-new cluster headache treatment, Journal of Pain, 5(supplement 1): 46, April 2004 Krusz, JC, Knoderer, WR, Migraine pre-emption with almotriptan, Journal of Pain, 5 (supplement 1): 86, April 2004 Krusz, JC, Knoderer, WR, Eletriptan for migraine pre-emption, Journal of Pain, 5 (supplement 1): 87, April 2004 Krusz, JC, "Intradermal botulinum toxin, type b, for migraine of cervical origin", Am J Pain Management, 14: Krusz, JC, Treatment of Chronic Pain with Zonisamide, Pain Practice, 3:317-20, December Krusz, JC, Prophylaxis for Chronic Daily Headache and Chronic Migraine with Neuronal Stabilizing Agents, Curr Pain and Headache Reports 6:480-5, Dec Semenchuk, MR, Krusz, JC, Restless Legs Syndrome, Chapter 6 in Use of alpha- 2 adrenergic agonists in pain management, edited by Childers, MK, p63-73, Academic Information Systems Krusz, JC, Chronic Headaches and a new Approach to Treatment Using Tizanidine, Chapter 9 in: Use of alpha-2 adrenergic agonists in pain management, edited by Childers, MK, p , Academic Information Systems Krusz, JC, Intravenous valproate sodium in the treatment of migraine headaches in the headache clinic, Headache Quarterly, 12: Krusz, J.C., Drug Misuse and Detoxification, in: Innovations in Pain Management. A Practical Guide for the Clinician. Edited by Richard S. Weiner, Ph.D., Volume 4, Chapter 50, pp 1-43, (Revised 2000) 2000 Krusz, J.C., Myofascial Pain Syndrome, Chronic Tension-type Headache, and Fibromyalgia, in: Current Trends in the Diagnosis and Treatment of Chronic Neuromuscular Pain Syndromes, (Monograph), August, American Academy of Pain Management 2000 Krusz, J.C., Tizanidine HCl: An Effective Novel Agent for Treatment of Chronic Headaches, in: Advancements in the Treatment of Neuromuscular Pain (Monograph), October, p44-5, Johns Hopkins University 2000 Krusz, J.C, Headaches- Less Disability With Newer Treatments, Texas Healthcare, (Houston and Dallas-Ft Worth editions) Vol 2 issue 10, Oct Krusz, JC, Chronic Pain: New Approaches Lead to a Better Lifestyle, Texas Healthcare (Houston and Dallas-Ft, Worth editions), Vol 3, issue 1, p20-1, January Krusz, J.C., Scott, V. and Belanger, J. Intravenous Propofol: Unique Effectiveness in Treating Intractable Migraine Headaches, Headache, Vol 40:41-6, March 2000 Krusz, J.C., Belanger, J, Mills, C, Tizanidine- a unique effective agent for the treatment of chronic headaches, Headache Quarterly, Vol 11:1, p 41-5 JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 11

12 1998 Kasper, M.E., Harrell, E.H., Jones, W.B., Krusz, J.C.: Neuropsychological Profile Associated with Silicone-gel Breast Implants, Journal of Nutritional and Environmental Medicine, 1998, 8: Krusz, JC, Dowben, RM, Neurology-the decade of the brain, Dallas Medical Journal, January, pp Krusz, JC, Neurobehavioral aspects of multiple sclerosis, MS Connection, Volume 2, Issue 3, September Krusz, JC, Koller, WC, and Ziegler, DK, Historical review: Abnormal movements associated with epidemic encephalitis lethargica, Movement Disorders, Volume 2, Number 3, pp Krusz, JC, Lathers, CM, Gerard-Ciminera, JL, Baskin, SI, Kelliher, GJ, Goldberg, PB, and Roberts, J, Role of the adrenergic nerve terminal in digitalis-induced cardiac toxicity: A study of the effects of pharmacological and surgical denervation. J. Cardiovasc. Pharmacol. 4: Krusz, JC, Lathers, CM, Kelliher, GJ, Ciminera, JL, Baskin, SI. and Goldberg, PB, Digitalis toxicity and the adrenergic nerve terminal, I: effects of 6-hydroxydopamine and surgical denervation, Fed. Proc. 40: Krusz, JC, Roberts, J, Lathers, CM, Gerard-Ciminera, JL, Baskin, SI, and Kelliher, GJ, Digitalis toxicity and the adrenergic nerve terminal, II: interaction of reserpine with 6-hydroxydopamine and bretylium. Fed. Proc. 40: Krusz, JC, Lathers, CM, Gerard-Ciminera, JL, Baskin, SI, Kelliher, GJ. And Roberts, J, The action of reserpine, 6-hydroxydopamine and bretylium on digitalis-induced cardiotoxicity. Europ. J. Pharmacol. 76: Baskin, SI, Cohen, EM, Leibman, AJ, and Krusz, JC, The effect of decentralization and denervation on taurine metabolism, Fed. Proc., Greenberg, MI, Roberts, JR, Krusz, JC, and Baskin, SI, Endotracheal epinephrine in a canine anaphylactic shock model, JACEP, 8: , Krusz, JC, Kendrick, ZV, and Baskin, SI, Pineal taurine content. In Bowden, D. M., ed., Aging in Nonhuman Primates. New York: Van Nostrand Reinhold Co., pp Baskin, SI, Krusz, JC, Samuels, T, Weinhardt, A, Kelliher, G, Lathers, C. and Roberts, J, Role of the adrenergic nerve terminal in digitalis-induced cardiac toxicity, Clin. Res., 27(2): Krusz, JC, Dix, RK, and Baskin, SI, Factors that affect endogenous content and uptake of taurine in the rat pineal, Fed. Proc., 37: Krusz, JC, Baskin, SI, and Kendrick, ZV, Age-related changes in pineal taurine content in the aging rat and monkey, Gerontologist, Baskin, SI, Leibman, AJ, DeWitt, WS, Orr, P, Tarzy, N P, Levy, PI, Krusz, JC, Dhopesh, VP, and Schraeder, PL, Mechanism of the anticonvulsant action of phenytoin: Regulation of central nervous system taurine levels, Neurol., April 1974 Krusz, JC, Occurrence and experimental alteration of endogenous 5-hydroxytryptamine in peripheral sympathetically innervated organs. Doctoral dissertation: State University JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 12

13 of New York. Downstate Medical Center, Brooklyn, New York Krusz, JC, and Wakade, AR, Occurrence of 5-hydroxytryptamine (5HT) in sympathetically-innervated organs and its experimental alteration after denervation and drug treatment, Pharmacologist, 15: Wakade, AR, and Krusz, JC, Effect of reserpine, phenoxybenzamine and cocaine on neuromuscular transmission in the vas deferens of the guinea pig, J. Pharmacol. and Exper. Therapeutics. 181: Submitted for Publications 2005 Krusz, JC, Intradermal Botulinum toxin administration: novel delivery route for treating pain and headaches, submitted to Expert Opinion on Drug Delivery 2005 Krusz, JC, Cagle, J, Scott, V, Treatment of Status Migrainosus with IV sodium valproate 2005 Krusz, JC, and Nett, RB, Naratriptan for the Prevention of Migraine Recurrence after Initial Relief with Sumatriptan (submitted to Headache and Pain) 2005 Treatment of Migraines of Cervical Origin with Intradermal Botulinum toxin, type A (submitted to Cephalalgia) 2005 Krusz, JC, Intravenous Treatment of Intractable Headaches in the Clinic Setting, submitted to: Expert Opinion on Pharmacotherapy 2005 Krusz, JC, IV Treatment of Chronic Daily Headaches in the Outpatient Headache Clinic, submitted to: Current Reports Pain and Headache Poster and Seminar Presentations 2 posters for AHS 08 meeting, Boston, MA, Accepted for June John Claude Krusz, PhD, MD, Virginia Scott-Krusz, BS, Stephanie K Hall, BS, MPH, and Jane Cagle, LVN, Intravenous (IV) Ketamine for mixed migraine and pain disorders in the clinic 2008 John Claude Krusz, PhD, MD, Jane Cagle, LVN, Stephanie K Hall, BS, MPH, Intramuscular Ketamine for refractory mixed headache and pain flare-ups 4 posters for APS 08 meeting, Tampa, FL, Accepted for May John Claude Krusz, PhD, MD, Stephanie K Hall, BS, MPH, Diane Cammarata, APRN, BC, and Jane Cagle, LVN. Efficacy of IV Lidocaine to treat pain and headache flare ups in the outpatient clinic 2008 John Claude Krusz, PhD, MD, Jane Cagle, LVN, Stephanie K Hall, BS, MPH, Intramuscular (IM) Ketamine for treating headache and pain flare-ups in the clinic 2008 John Claude Krusz, PhD, MD, Stephanie K Hall, BS, MPH, Jane Cagle, LVN. Efficacy of IV Ketamine for pain Treatment in the outpatient clinic JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 13

14 2008 John Claude Krusz, PhD, MD, Jane Cagle, LVN, Stephanie K Hall, BS, MPH, Efficacy of IV Ketamine in treating refractory migraines in the clinic 2 posters for ANPA 08 meeting, Savannah, GA, Accepted for March poster for AHS06 meeting, Accepted for June Cagle, J, Scott-Krusz, V, Belanger, J, Krusz, J; IV treatment efficacy for refractory migraines in the outpatient clinic 5 posters for APS06 meeting, Accepted for June V Scott, D Cammarata, J Krusz, Dihydroergptamine nasal spray for pre-emption for menstrual/ early AM migraines. J Krusz, S Hall, J Cagle: Intradermal Botulinum, type B, for treating migraines of cervical origin. J Krusz; IV Pain and Headache Treatment in the Outpatient Setting D Daniel, J Cagle, J Krusz; IV tramadol: Effective treatment for refractory migraines in clinic D Cammarata, J Krusz: Memantine for migraine prophylaxis Radio presentation: "Informed, equipped & empowered to fight chronic pain together," National Chronic Pain Society 2006 Krusz, JC, Adjuvant analgesics: their role in the long-term treatment of pain, in Dialogues in Persistent Pain, CME Monograph, sponsored by Dannemiller Memorial Education Foundation, July 2 posters for ANPA05 meeting Bal Harbour Miami, Accepted for March A prospective study of cognitive enhancement with galantamine increased over four months in patients with traumatic brain injury. John Claude Krusz, Stephen Roberts, Jack Thomson 2005 Donepezil for cognitive enhancement after traumatic brain injury. John Claude Krusz, Alan C. Hopewell, John A. Thomson, Stephen Roberts 2 posters for APS05 meeting Boston, Accepted for March J Krusz, J. Cagle, D. Daniel, W. Knoderer, Intravenous Levetiracetam for cluster Headache treatment in the clinic 2005 J Krusz, Intradermal Botulinum toxin type A, in treating pain syndromes 1 poster for AAN05 meeting Miami, Accepted for April 2005 JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 14

15 2005 Hopewell, CA, Thomson, JA, Roberts, S, Krusz, JC, Galantamine as treatment for cognitive dysfunction after traumatic brain injury, poster abstract, American Academy of Neurology 57th annual meeting, Miami, Neurology 64(suppl 1): A355, posters AHS meeting, Philadelphia, June Cammarata, D, Krusz, JC, Memantine: Novel Mechanism for Migraine and Headache Prophylaxis, 47th Annual Scientific Meeting of the American Headache Society, June, Philadelphia, Pennsylvania, Headache 2005 Krusz, JC, Ziprasidone: Effective Treatment for Chronic Daily and Chronic Migraine Headaches, 47th Annual Scientific Meeting of the American Headache Society, June, Philadelphia, Pennsylvania, Headache 2005 Krusz, JC, Dihydroergotamine Nasal Spray (Migranal NS ) For Pre-Emption Of Menstrual/Early Morning Migraines, [poster abstract] 47th Annual Scientific Meeting of the American Headache Society, June Philadelphia, Pennsylvania, Headache Posters shown at IASP meeting, Sydney, Australia, August William R Knoderer, DDS, MD, John Claude Krusz, PhD, MD, 2005 Intradermal botulinum toxin, type A, to treat pain disorders, 8 posters shown at EFNS meeting Athens, Greece September Diane Cammarata, ANRP, BC, John Claude Krusz, PhD, MD, Ziprasidone as prophylaxis for chronic daily headaches, 2005 Virginia Scott-Krusz, Jeanne Belanger, RN, Jane Cagle, LVN, 2005 John Claude Krusz, PhD, MD, Effectiveness of IV therapy in the headache clinic for refractory migraine, 2005 John Claude Krusz, PhD, MD, Jane Cagle, LVN, Dan Daniel, RPh, IV levetiracetam for treatment of cluster headaches in the clinic, 2005 John A Thomson, MS, LPC, C Alan Hopewell, PhD, ABPP, John Claude Krusz, PhD, MD, Galantamine for cognitive dysfunction after traumatic brain injury, 2005 Jane Cagle, LVN, Virginia Scott-Krusz, John Claude Krusz, PhD, MD, IV tramadol for treatment of refractory headaches and migraines, 2005 Jane Cagle, LVN, Stephanie Hall, BS, MPH, Virginia Scott-Krusz, John Claude Krusz, PhD, MD, IV valproate sodium for status migrainosus in the clinic, 2005 John Claude Krusz, PhD, MD, Diane Cammarata, ANRP, BC, Memantine for chronic migraine prophylaxis, 2005 William R Knoderer, DDS, MD, John Claude Krusz, PhD, MD, Intradermal botulinum toxin, type A, to treat pain disorders, JOHN CLAUDE KRUSZ, Ph.D., M.D. CV - 5/26/08 page 15

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