ender SEX GENDER What is gender medicine? Karin Schenck-Gustafsson, MD, PhD Symptoms Genus Genetics Abuse Hormones

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1 What is gender medicine? Karin -Gustafsson, MD, PhD Professor of Cardiology, Karolinska University Hospital Director and Founder, Centre for Gender Medicine, Karolinska Institutet Strategic Councillor, Equality and Equity karin Sex SEX Biology Genetics Gender GENDER G Society ender Symptoms Genus Hormones Abuse

2 Socio-cultural What is the impact of being a man or a woman in the society? Mattel Co. Barbie and Ken Math is difficult Vengeance is mine 3 IGender aspect of diseases some examples Women Osteoporosis i Lungdiseases Rheumatic diseases Multipel sclerosis Alzheimer Eaing disorders Depression Fibromyalgia Cronic Fatigue Thyroid diseases Gallbladderstones Migraine Whip lash Men Myocardial infarction Infections Coloncancer Ulcus Diabetes Alcoholism Schizofrenia Atrial fibrillation Autism ADHD

3 Men and women experience health and disease differently Biology differs Aging is different in men and women Always consider sex and gender in Epidemiology Riskfactors Patophysiology Diagnostics Treatment Prognosis

4 Women live longer since 1750 in Sweden but lately the gendergap is decreasing (10 years to 3) Namn Efternamn 25 augusti ? Smoking Lipids Obesity Hormones Stress Socio-cultural factors Telomers

5 Telomere length Telomerase Nobel price 2009 Medicine/Physiology Women seek more health care

6 Women take more pills Women are prescribed more pills Drug utilization data from Swedish Board of Health and Welfare: 59% of all Swedish men and 75 % of all Swedish women take out at least one docotrs prescribed drug per year (2010) 12

7 hos män och kvinnor Soldin & Mattison. Clin Pharmacokinet 2009;48: On-going gender activity in Stockholm County Council (hospitals, general practioners) Education in equity and gender medicine for heads of departments since 2006, 800 chiefs have been educated CEMR-declaration accepted dec 2008, EU-meeting Stockholm May 2010 Development of gender tools in hospitals Pilot study on-going: stroke, AMI, hip-fractures, eye-operations Projects on equality indicators in health care Gender aspects on the use of medication HOUPE-study

8 Can Healthy Work Organization Prevent Suicidal Thoughts among Physicians? The University Hospital Physician (HOUPE) Study -- Results from Sweden Ann Fridner, PhD, 1, 2 Karen Belkic, MD, PhD, 2, 3 Massimo Marini, MSc, 4 Birgit Pingel, PhD, 1Lise Lövseth, PhD Candidate, 5 Lilja Sigrún Jónsdóttir, MD, 6 Karin -Gustafsson, MD, PhD, 2 J Gender Medicine 2010 Centres for Gender Medicine in Europe Stockholm, Karolinska Institutet, Sweden, 2001 (Prof.Karin -Gustafsson) Berlin, Charite University, Germany, 2004 (Prof. Vera Regitz-Zagrosek) Vienna, Austria, University of Vienna 2006 (Prof. Jeannette Strametz-Juranek) Modena,Italy, 2004 (Prof. Maria-Grazia Modena) Padova, Italy 2009 (Prof. Giovanella Baggio) Tel Aviv, Israel, 2010 (Prof. Marek Glezermann)

9 Europe: International Society of Gender Medicine USA: OSSD (Organization for th Studies of Sex Differences) Centre for Gender Medicine, Karolinska Institutet since 2001 Initiated by Prof. Karin -Gustafsson and Prof. Harriet Wallberg-Henriksson, KI s president Funding: Karolinska Institutet, Wallenberg Foundation, AFA Insurance Company Stockholm County Council, 1.6 million club (calender) Organisation: A board with a chair and 5 members from Karolinska Institutet s faculty 2 external members A director An administrative assistant A core research committee An executive committee Researchers and educational leaders Inauguration with Queen Silvia

10 Centrum för Genusmedicin Omkring 25 personer Berlin 2009 Nobel Forum oct years with Center for Gender Medicine Past, Present and Future Monday October 17th, 2011, Rolf Luft Center, Karolinska University Hospital, Solna 8:00-8:55 8:30-8:55 8:55-9:00 9:00-9:30 9:30-10:00 10:00-10:15 Chair: Noel Bairey Merz 10:15-10:30 10:30-10:45 10:45-11:00 11:00-11:30 11:30-12:00 12:00-13:00 14:00-14:30 14:30-15:00 15:15-15:45 15:45-17:00 Coffee at Faculty Club (Invited) Coffee and registration Welcome: Karin -Gustafsson Inauguration: H.M. Queen Silvia, Harriet Wallberg-Henriksson, The devolepment of Gender Medicine in the world Marianne Legato, Columbia University, New York Center for Gender Medicine, Karolinska Institutet Karin -Gustafsson, Ingrid Lundberg Gender Medicine at Stockholm County Council Birgitta Rydberg, Politician, Stockholm County Council Gender perspectives when building a new hospital, NKS Lennart Persson, Fruit and refreshments The vulnerable man Marek Glezerman, Rabin Medical Center, Tel Aviv The vulnerable woman Virginia Miller, Mayo Clinic, Minnesota Research at the Center: Abstract show Katarina Bilén, Joakim Sturup, Elisabeth Örtqvist, Sebastian Gidlöf, Jocelien Olivier, Juan Jesus Carrero, Nina Johnston, Desirée Loikas, Natallia Luksha, Annika Berglund, Marie Gustafsson Female coronary artery disease Noel Bairey Merz, Cedars-Sinai Medical Center, Los Angeles LifeGene a goldmine for studies of gender medicine Nancy Pedersen The Power Study in Canada - what have we learnt about determinants of health and disease Arlene Bierman, University of Toronto C Health care seeking - Why do women and men behave differently?

11 Jan 2012 Karger Handbook of Clinical Gender Medicine 2009 Editor in Chief Karin -Gustafsson Center for Gender Medicine impact Gender Medicine is one of the most exciting and rapidly growing areas in science and medicine and one of the most important developments of the 21st century. and very important for the optimal care and treatment of both men and women

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