Technology and Product Development
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- Ambrose Thornton
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1 Technology and Product Development
2 Start with us to take your idea from concept to commercial reality, or if you are already underway, let us help you lower your production costs and manage the impact of changing technologies. Contact us: callaghaninnovation.govt.nz 2 \ Technology and Product Development
3 R&D Grants Technology and Product Development Our world-class scientists and engineers can help you deliver your product development R&D and achieve better levels of productivity and innovation. To help you get fast access to the R&D support you need, we have scientists and research capabilities in six network groups: Advanced materials Information Communication and Technologies (ICT) Biotechnologies Manufacturing and design Sensing and automation Measurement standards. You can also search our database of published research in a range of academic journals. Who are our clients? We work with businesses of all sizes, nationally and internationally, across a broad range of industries. Who owns the intellectual property? If your business is paying for R&D then you will own the intellectual property (IP). We can help you develop and implement the best IP strategy for protecting your investment. How are services charged for? We provide a written estimate for all work. Depending on the nature of the work, either a fixed price or a time and materials estimate will be provided. You will need to approve the cost estimate before work is undertaken. How do you engage our Technology and Product Development services? Phone us on CALLAGHAN ( ) and we ll connect you with one of our business relationship managers, who will talk to you about our specific business requirements. Technology and Product Development \ 1
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5 Our areas of expertise Advanced materials helping you select the best materials for your product or process development, developing new materials and materials characterisation and testing Information and communication technologies (ICT) helping you with the design and implementation of ICT solutions from data analytics to smart materials Biotechnologies helping you transform biological resources into high-value products, including nutraceuticals, cosmeceuticals, food ingredients and natural agrochemicals. Providing high quality and fast-paced pharmaceutical substance development and manufacturing to enable human proof-of-concept studies. Manufacturing and design helping you solve complex design challenges throughout product development from concept feasibility and testing through to production and commercialisation Sensing and automation helping you solve product engineering challenges applying electronics and embedded software design, signal processing, sensor systems, automation and robotics to deliver commercially viable products Measurement standards helping you understand your products and processes with world-class calibration and verification, measurement advice and consultancy services and R&D on measurements and measuring instruments. Technology and Product Development \ 3
6 Advanced materials Our advanced materials experts can help you select the best materials for your product or process development, materials characterisation and testing. We ll help your business get the best results with our expertise in: Optimal materials selection Advising you on the best choice of materials for your product or process. A wide range of materials and process development Titanium powder metallurgy and ultra-lightweight foams expertise Materials characterisation and testing Materials characterisation including X-ray crystallography, particle sizing, density/porosity measurement, optical and electron microscopy Synchrotron science and analysis Optical characterisation of materials, from UV-VIS to advanced non-linear techniques A range of physical and mechanical property testing from thermal analysis to strength and hardness. Testing and development of conventional and novel cementing systems Surface treatments and coatings with enhanced durability and functionality Advanced materials synthetic chemistry, including organic dyes, polymers, and nanoparticles Advanced ceramics and ceramic composite systems Materials for optical detection, spanning material synthesis to prototype development Fibre optics sensing systems for harsh environments High-temperature processing, process engineering and control systems. 4 \ Technology and Product Development
7 Information & Communication Technologies (ICT) Our Information and Communication Technologies (ICT) experts can help your business with a wide range of ICT challenges. They can help you design and implement solutions in areas from data analytics to smart materials. We ll help your business get the best results with our expertise in: Data science and analytics Data harmonisation Statistical predictive modelling and machine learning Network analysis. Medical device design and implementation Translation of devices and concepts into rehabilitation systems Advice on regulatory and commercialisation strategies Planning and execution of clinical device trials Computational mechanics and simulation Finite element simulation of solids and structures Molecular dynamics and DFT modelling of nano and microstructures Analysis of sound and vibration. Product development and testing Design and fabrication of metamaterial sound and thermal insulators Lightweight high-impact MIL-S-901D shock testing Design and implementation of novel mechanical tests. Facilitation of multi-disciplinary projects involving human-computer interaction. Technology and Product Development \ 5
8 Biotechnologies Our biotechnologies experts can help your business to transform biological resources, such as meat, dairy, plant and seafood products, into high-value products that include nutraceuticals, cosmeceuticals, food ingredients and natural agrochemicals. Our experts can also deliver you a competitive advantage in pharmaceutical drug discovery and development. We ll help your business get the best results with our expertise in: Lipid chemistry Extraction, purification, synthesis, modification, enrichment and analysis of lipids (including phospholipids and glycolipids). Natural products and plant chemistry Extraction, purification and analysis of bioactives such as anti-inflammatories, flavonoids, pigments, food ingredients/fortifiers and antioxidants. Carbohydrate and pharmaceutical chemistry Multi-step chemical synthesis and complex problem solving. Development and manufacturing services involving active pharmaceutical ingredients (API s) ranging from conventional small molecules to dendrimers and complex carbohydrates. Our services cover discovery through to prototype scale-up and kilogram-scale GMP manufacture to support clinical studies. Analytical services Access to a range of instrumentation including nuclear magnetic resonance (NMR) spectrometers, mass spectrometers (MS), high performance liquid chromatography (HPLC), Zetasizer for product formulation and services: UV-vis spectrometers, moisture content analyser, assay development, particle size and rheological property measurement, protein purification and characterisation (AKTA systems), molecular weight determination (SEC), florescence analysis and time resolved fluorescence for bioassays and enzyme assay work. Process development and pilot-scale facilities Development and/or evaluation of industrial manufacturing processes for natural products. Process modelling, optimisation and scale-up. Evaluation of unit operations including milling, solvent and supercritical fluid extraction and fractionation, solvent removal/evaporation, filtration, freeze drying, formulation, preparative chromatographic separation, centrifugation, chemical and enzymatic reaction. Pilot to small scale manufacture of trial product, including rated facilities for use of ethanol and other flammable solvents. MPI approved manufacture of selected products. 6 \ Technology and Product Development
9 Supercritical fluid extraction World class facilities for evaluation of supercritical fluid processing from lab to pilot scale. Includes use of supercritical CO 2, CO 2 with co-solvents, and novel liquefied gas solvents (propane and dimethyl ether). This technology is ideal for extraction and/or fractionation of high quality lipid and other low polarity products from natural materials. Fermentation and bioprocessing MPI-registered facility, pilot-scale fermentation from 1L to 1000L Small molecule and secondary metabolite production, pilot plant micro and ultrafiltration, continuous centrifuge EPA approvals for large scale recombinants (1000L) new organisms and bacterial/yeast recombinants PC2 level. Proteins and bioactive peptides Isolation and characterisation for structure and function determination Extraction and preparation of biopolymers from various natural resources including plant, animal, marine and honey. Enzyme technology Optimisation of enzymes for industrial applications including biotransformation and chemo-enzymatic synthesis Full suite of recombinant technologies for the enzyme engineering, including molecular cloning, expression, purification and characterisation of proteins, enzymes and biomolecules. Expression in bacterial, yeast, and mammalian hosts Scale-up facilities to deliver microbial recombinant expression to 1000L. Biology and biochemistry Biological materials processing using biomimicry (such as ECM isolation from sheep stomach) Use of LEDs light frequencies to activate photo-reductive Fenton chemistry Development and alignment of processing methods (such as photo-fenton processing methods) to turn waste into functional ingredients and mimicking these at pilot and industrial scale Development of combination processing technologies by combining DAF bubbles and biological colloidal systems to increase catalytic rates of reaction Development of new rendering processing methods to recover greater value from New Zealand primary industries. Technology and Product Development \ 7
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11 Manufacturing and design Our experts in manufacturing and design can help convert your ideas into commercially viable market solutions. We ll help you solve your complex design challenges throughout the development process from concept feasibility and testing through to production and commercialisation. We ll help your business get the best results with our expertise in: Mechanical and electrical engineering High-level calculation, analysis and on-call design horsepower. Thermodynamics, fluids, vibration and strength analysis, and computational engineering Prototype manufacture, testing and development Our access to an extensive network of New Zealand manufacturers means you get the best value on prototype builds. And our in-house capability means prototypes can be tested and developed rapidly, saving you valuable time. Manufacturing process and machinery development Incorporate new technologies into processes, machinery and products Development of new manufacturing processes to improve production. Precision machining and manufacture Grown through in-house work serving scientists and optical manufacture for astronomy. Product development Develop new and improved products through the application of new technologies and expertise in engineering, design and manufacturing. Optical component manufacture World leaders in mirrors, very large lenses and ancillary equipment manufacture. Structuring complex and challenging development projects Tackling the new and difficult Finding the path through all stages of development Our sweet spot is TRL 2 (proof of concept) to TRL 6 (demonstrated in real environment). Instrumentation Getting the best value from the measurements you need. Technology and Product Development \ 9
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13 Sensing and automation Our sensing and automation experts can help you solve your product and process development challenges from initial concept, to production prototype, to delivering commercially viable products and technology solutions. We ll help your business get the best results with our expertise in: Systems design and engineering Ensuring modular designs with robust interfaces. Electronics and embedded software Soak-tested, single-board prototypes. Mechanical engineering Applying high-end design tools to complex design challenges. Robotics and automation Processing naturally varying horticulture and agriculture produce. Machine intelligence Developing smart systems that react appropriately to new situations. Computer vision Production of dimensionally accurate three-dimensional models. Digital signal processing Extracting useful information from noisy, degraded or incomplete data. Field programmable gate arrays Efficient implementation of digital signal processing for high-speed operation. Wireless, audio and sonar technologies Deep, applications-specific knowledge to inform design choices. Microfabrication and microfluidics State-of-the-art facilities, equipment and expertise with access to national networks. Transducer design and fabrication Custom design of piezo-ceramic transducers and transducer arrays. Ultrasonic, microwave and optical sensing Industrial inspection and measurement using multiple modalities. Technology and Product Development \ 11
14 Measurement standards Our team of testing and measurement experts can help you to understand your products and processes with world-class calibration and verification, measurement and consultancy services (including technical advice on difficult measurements) and R&D on measurements and measuring instruments. We ll help your business get the best results with our expertise in: Measurement Standards Laboratory (MSL) MSL is New Zealand s national metrology institute responsible for the provision of physical measurement standards in New Zealand. Specialist calibration services for instruments and equipment Length and related quantities Low-frequency electrical including power metering Mass and related quantities Photometry and radiometry Measurement verification Traceability to National Measurement Standards ISO accredited calibrations International acceptance of measurements. Specialist technical consultancy services and advice Measurement solutions and compliance Research to improve the International System of Units (SI) and solve measurement problems. Advice and training Technical guides and resources on measurement techniques, traceability, instrument use and methods for calculating uncertainty. Radio frequency and microwave Temperature and humidity Time and frequency. 12 \ Technology and Product Development
15 Technology and Product Development \ 13
16 We also help you with: Access to Experts Business Collaborations Innovation Skills R&D Grants Contact us: callaghaninnovation.govt.nz TCHDEV_09_2015
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