8:50 Opening statement - Dr. Felipe José Fernández Coimbra (Head of the Department of Abdominal Surgery, Hospital A. C.

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1 IV SYMPOSIUM OF THE GASTROINTESTINAL ONCOLOGY CONTINUING MEDICAL EDUCATION PROGRAM - DEPARTMENT OF ABDOMINAL SURGERY, SURGICAL ONCOLOGY, A. C. CAMARGO CANCER HOSPITAL ESOPHAGOGASTRIC CANCER AND GIST SCIENTIFIC PROGRAMMING AUGUST 12 TH, :00 8:50 Registration / Breakfast 8:50 Opening statement - Dr. Felipe José Fernández Coimbra (Head of the Department of Abdominal Surgery, Hospital A. C. Camargo -SP) 9:00 SESSION 1 Epidemiology and screening in esophagogastric tumors Chairman: to be defined Secretary: Dr. Evandra Vieira Rocha (Gastroenterologia Clínica, Discussants: Dr. Maria Dirlei Ferreira de Souza Begnami (Surgical Pathology, Hospital A. C. Dr. Adriane Graicer Pelosof (Departamento de Endoscopia, Hospital A.C Camargo SP) 9:00 9:15 What is the population at risk for esophageal and gastric cancer? Should we perform screening, for whom and how? Dr. Rubens Kesley (Abdominopelvic Surgery, Instituto Nacional de Câncer-RJ) 9:15 9:30 Update in diagnosis criteria and molecular basis in patients with familial gastric cancer. Dr. Maria Isabel Alves Waddington Achatz (Oncogenetics, 9:30 9:45 What is the role of molecular pathology in the diagnosis and managment of Barrett`s esophagus? Applying basic science in clinical practice. Dr. Fernando Augusto Soares (Surgical Pathology, 9:45 10:10 Questions & Answers 10:10 10:40 CONFERENCE Molecular biology of gastroesophageal cancers President: Dr. Maria Dirlei Ferreira de Souza Begnami (Surgical Pathology, Hospital A. C. Discussant: Dr. Jaffer A. Ajani (M. D. Anderson Cancer Center) 10:40 11:00: COFFEE BREAK 11:00 SESSION 2 Multidisciplinary treatment modalities for gastric adenocarcinoma Chairman: Dr. André Luís Montagnini (Digestive Surgery, HCFMUSP-SP)

2 Secretary: Dr. Adalberto Rios (Surgical Oncology, HCACC) Discussants: Dr. Jaffer A. Ajani (M. D. Anderson Cancer Center) Dr. Paulo Kassab (FCMSC-SP) 11:00 11:10: The Western view. Dr. Maria Nirvana Formiga (Medical Oncology, Hospital A. C. Camargo SP) 11:10 11:20 The Eastern view. Dr. Alessandro Landskron Diniz (Abdominal Surgery, Hospital A. C. Camargo-SP, BGCA) 11:20 11:30 Where does Brazil stand? Dr. Marcelo Ferretti Fanelli (Medical Oncology, 11:30 11:50 Discussion 11:50 12:20 CONFERENCE New Surgical Treatment Guidelines of the Japanese Gastric Cancer Association (JGCA). Chairman: Dr. Felipe José Fernández Coimbra (Abdominal Surgery, Hospital A. C. Camargo- SP, BGCA) Speaker: to be defined 12:20 14:00 LUNCH 14:00 SESSION 3 - Controversies in the treatment of esophagogastric tumors Chairman: Dr. Paulo Henrique de Sousa Fernandes (Surgical Oncology, Universidade Federal de Uberlândia-MG) Secretary: Dr. Eron Machado Cobe (Surgical Oncology Discussants: Dr. Antônio Weston (Digestive Surgery, Complexo Hospitalar Santa Casa de Porto Alegre-RS) 14:00 14:15 Is it necessary to individualize the treatment of gastric cancer in elderly patients? Dr. André Luís Montagnini (Digestive Surgery, HCFMUSP-SP) 14:15 14:30 TNM 7 th Ed. Can we improve staging in esophagogastric cancer? Dr. Paulo Kassab (Santa Casa de Misericórdia-SP, Mestre do Capítulo de São Paulo do Colégio Brasileiro de Cirurgiões, BGCA) 14:30 14:45 What is the best surgical approach for locally advanced gastroesophageal junction tumors? Dr. Felipe José Fernández Coimbra (Abdominal Surgery, Hospital A. C. 14:45 15:00 Questions & Answers 15:00 - DEBATE Esophageal squamous cell carcinoma with complete clinical response after chemoradiotherapy: what to do next?? Moderator: Dr. Ricardo César Fogaroli (Radiotherapy,

3 15:00 15:15 Surgery always!! Dr. Rubens Antonio Aissar Sallum (Digestive Surgery, HCFMUSP-SP) 15:15 15:30 Follow-up is the best choice!! Dr. Celso Abdon Lopes de Mello (Medical Oncology, 15:30 15:50 Discussion 15:50 16:10 COFFEE BREAK 16:10 16:40 CONFERENCE - Individualization in the adjuvant treatment of GIST Chairman: Dr. Héber Salvador de Castro Ribeiro (Abdominal Surgery, Hospital A. C. Camargo- SP) Discussant: Dr. Bruno Vilhena Pereira (Medical Oncology, Instituto Nacional de Câncer- RJ) 16:40 DEBATE Gastrointestinal Stromal Tumor (GIST) with synchronic resectable liver metastasis Moderator: Dr. Laércio Gomes Lourenço (Digestive Surgery, UNIFESP-SP) 16:40 16:55 Medical treatment only!! Dr. Thiago Bueno de Oliveira (Medical Oncology, 16:55 17:10 Surgery always!! Dr. Héber Salvador de Castro Ribeiro (Abdominal Surgery, 17:10 17:30 Discussion

4 IV SYMPOSIUM OF THE GASTROINTESTINAL ONCOLOGY CONTINUING MEDICAL EDUCATION PROGRAM - DEPARTMENT OF ABDOMINAL SURGERY, SURGICAL ONCOLOGY, A. C. CAMARGO CANCER HOSPITAL ESOPHAGOGASTRIC CANCER AND GIST SCIENTIFIC PROGRAMMING AUGUST 13 TH, :00 SESSION 4 Singularities in the treatment of early esophagogastric tumors Chairman: Dr. Felipe Alves Retes (Upper Endoscopy, Secretary: Dr. Rafael Sodré A. Vasconcellos (Resident in Surgical Oncology, Hospital A. C. 9:00 9:15 Role of endoscopy in the evaluation and treatment of early esophageal and gastric tumors. Dr. Daniela Milhomem (Surgical Oncology, Hospital Araújo Jorge-GO) 9:15 9:30 Is it possible to individualize lymph node dissection in patients with early gastric cancer? Dr. Antônio Weston (Digestive Surgery, Complexo Hospitalar Santa Casa de Porto Alegre-RS, BGCA) 9:30 9:45 Indications and pitfalls in laparoscopic resections for gastric adenocarcinoma. Dr. Bruno Zilberstein (Digestive Surgery, HCFMUSP-SP, BGCA) 9:45 10:00 Questions & Answers 10:00 10:40 CONFERENCE Modern strategies in the treatment of localized esophageal cancer: multidisciplinary, biomarkers, imaging, and pathologic response. Chairman: Dr. Celso Abdon Lopes de Mello (Medical Oncology, Speaker: Dr. Jaffer A. Ajani (Gastrointestinal Oncology, M. D. Anderson Cancer Center-USA) 10:40 11:00 COFFEE BREAK 11:00 SESSION 5 Open questions in the multidisciplinary management of esophagogastric tumors. Chairman: Dr. Paulo Assumpção (Surgical Oncology, Universidade Federal do Pará-PA) Secretary: Dr. Alessandro Landskron Diniz (Abdominal Surgery, 11:00 11:15 Is there a role for adjuvant chemoradiotherapy in gastric cancer patients treated with D2-lymphadenectomy? Dr. Marcelo Leite Vieira Costa (Surgical Oncology, Instituto do Câncer do Ceará-CE)

5 11:15 11:30 Esophageal squamous cell carcinoma vs. adenocarcinoma should we use the same preoperative treatment modalities? Dr. Milton José de Barros Silva (Medical Oncology, 11:30 11:45 The problem of the peritoneal recurrence. What to do? Dr. Wilson Luiz da Costa Júnior (Abdominal Surgery, Hospital A. C. Camargo-SP, BGCA). 11:45 12:00 Questions & Answers 12:00 13:15 CASE DISCUSSION PANEL Presenters: Dr. Wilson Luiz da Costa Junior and Dr. Alessandro Landskron Diniz Discussants: Dr. Jaffer A. Ajani Dr. Antonio Weston Dr. Bruno Zilberstein Dr. Paulo Kassab Dr. Bruno Vilhena Pereira Dr. Laércio Gomes Lourenço Dr. Marcelo Leite Vieira Costa Dr. Paulo Assumpção Dr. Paulo Henrique de Sousa Fernandes Dr. Felipe JF Coimbra 13:15 FINAL STATEMENTS

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