Joint Replacement Surgeons of Indiana Foundation Laboratory Review

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1 Joint Replacement Surgeons of Indiana Foundation 2012 Laboratory Review

2 Program Overview The Joint Replacement Surgeons of Indiana (JRSI) Research Foundation is a not-for-profit organization committed to fostering the advancement of orthopaedic patient care through clinical and engineering research and education. The O rth opaedic Bi omedical Engineering Laboratory is a partnership between JRSI and Rose-Hulman Institute of Technology in which students gain laboratory experience while participating in timely research focused on improving implant design and surgical techniques. This program update is an overview of the growth of our program and the achievements of our students during In the past year JRSI has facilitated in-depth research experiences to 9 undergraduate engineering students, sponsored 2 masters degree candidates in thesis research projects, facilitated 6 summer research internships in the laboratory and 5 additional internships for students of other universities at our clinical research facility in Mooresville, Indiana. Through the infusion of high-tech instrumentation with clinical and industrial collaboration, our students have made numerous contributions to the orthopaedic community while developing unique engineering skillsets.

3 Contributing to the Global Knowledgebase The primary aim of the JRSI Foundation is to generate high-quality, peer-reviewed literature in an effort to contribute to the global orthopaedic and engineering communities. In the past year, we presented our research within the following national conferences and medical journals: The Influence of Bone Resection Depth on Tibial Loading Orthopaedic Research Society Annual Meeting, San Francisco, CA, February 2012 Student Author: Susumu Tokunaga Acetabular Cup Deformation in Metal-on-Metal Designs American Academy of Orthopaedic Surgeons, San Francisco, CA, February 2012 Student Author: Betsy Jones Digital Image Correlation Analysis of Rotating Platform Total TKA Orthopaedic Research Society Annual Meeting, San Antonio, TX, January 2013 Student Authors: Jordan Oja and Derek Archer Deformation in THA Press-fit Cup Designs Clinical Orthopaedics and Related Research; Student Author: Betsy Jones High Initial Stability in Porous Titanium Acetabular Cups Journal of Arthroplasty; Student Author: Leah Howard Acetabular Stiffness and Implant Orientation Change Acetabular Loading Patterns in THA Journal of Arthroplasty; Student Authors: Leah Howard and Didem Tunc Tibial Loading after UKA: Evaluation of Tibial Slope, Resection Depth, Medial Shift and Component Rotation. Journal of Arthroplasty; Student Authors: Derek Archer, Amanda Kingman

4 A Student Thank You To the Supporters of the Rose-Hulman-JRSI Research Partnership: Rose-Hulman provides its students with exceptional opportunities, one of which is the partnership with the Joint Replacement Surgeons of Indiana (JRSI). In one summer of research at JRSI s Rose-Hulman lab, I had access to more research experience and opportunities than most undergraduate students could hope for. My experience with JRSI s excellent equipment and the facilities available at Rose-Hulman has set me apart as an applicant for graduate school. In addition to the excellent equipment and facilities available to students doing research with JRSI, I was also able to learn how research studies are designed and implemented. I was able to contribute to developing the test methods and perform the testing and data analysis for the study now published in Clinical Orthopaedics and Related Research. I was also honored to give an oral presentation of the research at the BMES Annual Meeting that year. Seeing a study through from test methods to results is a unique opportunity. Having that study published in a major journal and presenting the research at a major conference before completing my Bachelor s degree is exceptional. I would not have had such exceptional accomplishments without the opportunities provided to me by JRSI. Scott Small makes it clear to the students working in the lab that he wants us to gain valuable, worthwhile research experience. The students are actively involved in every stage of a study.

5 This provides the students of Rose-Hulman with the opportunity to gain valuable and worthwhile research experience that sets us apart in a significant way. I am now applying to graduate school programs focused on Biomechanics and Orthopedic Engineering. The experience and accomplishments that JRSI has made possible have given me a priceless advantage. I am very grateful to Scott Small and JRSI and to Rose-Hulman for continuing to provide exceptional opportunities that help the students of Rose-Hulman to excel. Yours sincerely, Mary ( Betsy ) Jones Betsy has a passion for both biomedical engineering and the United Kingdom. She aims to study in a biomechanics graduate program at either the University of Oxford in Oxford or Imperial College in London, beginning in the fall of 2013.

6 2012 Undergraduate and Gra Derek Archer Class of 2012 Currently in a Doctoral Program at the University of Florida Betsy Jones Class of 2013 Kevin Farley Class of 2014 Allan Che Class of 2013 Master s Degree Candidate Emily Lakes Class of 2013 Kelli Greenberg Class of 2014

7 duate Student Researchers Audrey Niverson Class of 2014 Amanda Kingman Class of 2014 Paige Cook Class of 2014 Jordan Oja Class of 2012 Currently working as an Assistive Medical Device Design Engineer for Invacare, Inc. Brian Sutterer Class of 2014 Master s Degree Candidate

8 Current Investigations Evaluation of Micromotion in Fixed and Mobile Bearing Total Knee Arthroplasty Designs Summary: Excessive micromotion in total knee replacement is an indication of an unstable implant. This study compares two tibial component designs to identify differences in initial stability following implantation. Assessment of Dynamic and Static Balance After Partial and Total Knee Arthroplasty Summary: Patient balance after joint replacement surgery is crucial to limiting risk of falls and subsequent injury. This study compares balance before and after surgery in patients with partial and total knee replacements. Analysis of Heat Generation and Torque in Deformed Total Hip Arthroplasty Acetabular Components Summary: Previous studies have shown that some acetabular components change shape once implanted into the pelvis. This study examines the effect of that shape change on friction, torque, and heat generation at the ball-and-socket joint.

9 Finite Element Modeling of the Tibia Following Unicompartmental Knee Arthroplasty Summary: Computer imaged-based modeling allows for quick and efficient study of the interactions between bone and implant following arthroplasty surgery. This study is the development of a validated computational model of partial knee arthroplasty. Comparison of Manufactured Composite Tibia Models with Native Tissue Summary: Manufactured bone models exist to enable clean and repeatable biomechanics research. This study is an attempt to compare the mechanical response to joint replacement surgery of manufactured tibias versus cadaveric human tissue.

10 Student Experiences within the Healthcare Setting Through the JRSI research program, Rose-Hulman engineering students gain unique exposure to the medical community. Students in our program each spend a day in the operating room at the Center for Hip and Knee Surgery in Mooresville, Indiana observing JRSI orthopaedic surgeons performing hip and knee replacement surgeries. In 2012 our students additionally worked with a local imaging center collecting CT imaging data for use building threedimensional computational models of tissue specimens. JRSI surgeon Michael Berend, MD made multiple lab visits in 2012 to participate in biomechanical testing and to offer hands-on demonstrations of surgical techniques to our students.

11 Community Outreach As a part of the mission of the Rose-Hulman JRSI relationship, our program is committed to outreach activities which recruit and train young students in the fields of engineering and medicine. For the past three years our laboratory has participated in the Rose-Hulman Exploring Engineering program. In this program, we invite elementary and middle school students into the laboratory to learn basic engineering principles while demonstrating research equipment and methods. In 2012 our laboratory hosted two groups of high school students for lab tours, as well conducted lessons on engineering and medicine for a group of 11 local homeschooled elementary students.

12 We would like to offer our sincerest gratitude to the following supporters: The Lookout Foundation The VWR Foundation The Piedmont Foundation The National Science Foundation Rose-Hulman IP/ROP Rose-Hulman IRC Weaver Undergraduate Research Program Mr. Howard Freers & Family Mr. Gregory Gibson & Family Mr. Jack Ragle & Family Cover photo courtesy of Rose-Hulman Institute of Technology

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