Prof. Peter M.T. PATTYNAMA, MD, PhD

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1 Prof. Peter M.T. PATTYNAMA, MD, PhD (Curriculum vitae, February 2012) Personal data Name Peter Martin Theodoor PATTYNAMA Place-, date of birth Rotterdam, 1962 Nationality Dutch BIG-registration nr (Netherlands) Medical Specialist registry, radiologist GMC reference nr (United Kingdom) Full medical specialist, radiologist Work address Groene Hart Ziekenhuis Bleulandweg HH Gouda Tel: Current position Consultant radiologist/interventional radiologist Radiology Group Groene Hart Ziekenhuis, Gouda 1

2 Training & professional experience Medical School, University Leiden, Netherlands 10 July 1987 Physician examination, cum laude 28 Jan 1988 Foreign Medical Graduate Examination in the Medical Sciences, USA Residency in radiology, University Hospital Leiden 1 Oct 1992 Dutch Board Certification in Radiology 14 June 1994 PhD thesis, University Leiden "Functional magnetic resonance imaging of the heart" (Philips-award for clinical-radiological research, 1994) 1 Oct July 1998 Consultant radiologist, University Hospital Leiden Chief, urogenital radiology Chief, cardiovascular & interventional radiology 1 Aug Feb 2010 Consultant radiologist, University Hospital Rotterdam/Erasmus MC Chief, cardiovascular & interventional radiology Program director. Fellowship interventional radiology 1 May May 2011 Full professor of interventional radiology, Erasmus MC 1 Feb 2010 to date Consultant radiologist, Groene Hart Ziekenhuis Gouda Extracurricular experience 1988 Adjunct-secretary Dutch Committee for bone tumours, Leiden 1992 Visiting Fellow, interventional radiology, Miami Vascular Institute, Miami, Florida Fellowships interventional radiology societies Fellow, Society of interventional radiology, SIR (Formerly: Society of cardiovascular and interventional radiology, USA) Fellow, Cardiovascular and interventional radiological society of Europe, CIRSE European Board of interventional radiology (European diploma) Services to professional societies Vice Chairman, Dutch Society of radiology (NVvR) Vice Chairman, Dutch Society of radiology (NVvR), 2 nd term Secretary, UEMS radiology section (European union of medical specialists) President, UEMS radiology section 2003 present ESR/UEMS Educational committee & European training assessment program 2

3 Supervised PhD projects vd Linden E Oct 7, 2011 Percutaneous treatment of peripheral vascular malformations Hendriks J Jan 26, 2011 Carotid artery stenting and endarterectomy: a clinical evaluation Ouhlous M Nov 13, 2009 MRI and multi-detector CT angiography of the atherosclerotic plaque at the carotid artery de Weert TT Feb 6, 2009 Atherosclerotic carotid plaque assessment with multidetector CT angiography Spronk S Jan 16, 2008 Management of patients with intermittent claudication van Strijen MJL Mar 22, 2007 Diagnosing pulmonary embolism: establishing and consolidating the role of spiral CT (academic promotion at the University of Leiden) van den Berg WJ Feb 7, 2007 Functional cardiovascular assessment in congenital heart disease Kock MC Jan 24, 2007 Diagnostic imaging of peripheral arterial disease with multi-detector row computed tomography angiography Vogel MW Jan 12, 2005 Monitoring locally induced hyperthermia with MR imaging Moelker A Jun 30, 2004 Evaluation of acoustic noise in MR imaging Postema S Sep 28, 2000 Clinical significance of MR imaging in invasive cervical carcinoma (academic promotion at the University of Leiden) van Essen JA Jun 28, 2000 Validation and application of intravascular ultrasound in endovascular treatment of abdominal aortic aneurysm Leertouwer TC Jun 21, 2000 Stent placement for renal artery stenosis: Functional aspects and morphologic intravascular ultrasound parameters that define clinical success van Rossum AB Sep 3, 1998 Spiral volumetric computed tomography in patients suspected of pulmonary embolism (academic promotion at the University of Leiden) Membership academic PhD committees Promotion committee 29 Member of opposition 29 3

4 Funding, scientific projects 1. 4D Ultrasound for improved image guidance in minimally invasive needle interventions: the interventional cockpit. STW Stichting Technische Wetenschappen In collaboration with A. Freudenthal (TU Delft) and W.J. Niessen (TU Delft & Erasmus MC) 2. Transjugular intrahepatic portosystemic shunt (TIPS) using e-ptfe covered stent-grafts versus endoscopic treatment for acute bleeding from variceal varices. Doelmatigheidsonderzoek Erasmus MC , and ZonMW the Netherlands Organisation for Health Research and Development 3. Vessel wall characteristics after cryoplasty balloon angioplasty: intravascular ultrasound assessment in experimental animals. Boston Scientific, GREAT: Genesis peripheral stainless steel balloon expandable stent in REnal Artery Treatment. Prospective multicenter European trial of drug-eluting stents versus bare stents for atherosclerotic renal artery obstruction. Cordis, Johnson & Johnson, The diagnostic imaging work-up of living-related renal donors. VAZ-Doelmatigheid User-friendly interfaces for effective navigation through medical imaging data sets. Dutch Ministry of Economic Affairs/SENTER (Innovative Research Program/Human-machine interaction 99011) 7. ANTELOPE: Advances in New Technologies Evaluating the Localization of Pulmonary Embolism. Optimizing the diagnostic strategy in suspected pulmonary embolism: a multicenter trial. Ontwikkelings Geneeskunde Ziekenfondsraad (D94-90) 8. Clinical staging of cervical carcinoma of the uterus: Can it be replaced by MR imaging performed in an outpatient setting? Afwikkelings Geneeskunde; University Hospital Leiden Analysis of the pump function of the right ventricle by means of pressure-volume relationship in the normal and ischemic heart, as assessed with ultrafast MR imaging. Dutch Heart Foundation (NHS ) Investigator-sponsored projects 1. INPACT-Shunt Study, A multicenter randomized clinical trial of paclitaxel drug-eluting balloon (DEB) versus standard percutaneous transluminal angioplasty (PTA) to reduce restenosis in patients with hemodialysis access stenoses. Study PI. 2. MELOPEE Study, Popliteal artery stenting with self-expandable Nitinol stents. Study PI, together with Dr. Marc Bossiers 4

5 Publications a. Full papers, peer-reviewed 1. Nuyttens JJ,..., Pattynama PM, et al. Outcome of four-dimensional stereotactic radiotherapy for centrally located lung tumors. Radiother Oncol 2012; 102: Van der Linden E, van Baalen JM, Pattynama PM. Retrograde transvenous ethanol embolization of high-flow peripheral arteriovenous malformations. Cardiovasc Intervent Radiol 2011; Sep 8.Epub before pub. 3. Van der Linden E,..., Pattynama PM. Percutaneous treatment of peripheral vascular malformations in children: Long-term clinical outcome. Cardiovasc Intervent Radiol 2011 May Epub before pub. 4. Voûte MT, Hendriks JM,.., Pattynama PM,, Verhagen HJ. Radial force measurements in carotid stents: influence of stent design and length of the lesion. J Vasc Interv Radiol 2011; 22: Van de Laar IM,, Pattynama PM,, Bertoli-Avella AM. Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis. Nat Genet 2011; 43: Van Noord D, Sana A,, Pattynama PM,, Mensink OB. Endoscopic visible light spectroscopy: a new, minimally invasive technique to diagnose chronic GI ischemia. Gastrointest Endosc 2011; 73: Sana A, Vergouwe Y,, Pattynama PM,, Mensink PB. Radiological imaging and gastrointestinal tonometry add value in diagnosis of chronic gastrointestinal ischemia. Clin Gastroenterol Hepatol 2011; 9: Van Noord D, Biermann K,, Pattynama PM,, Mensink PB. Histological changes in patients with chronic upper gastrointestinal ischaemia. Histopathology 2010; 57: Nedeltchev K, Pattynama PM,, Cremonesi A. Standardized definitions and clinical endpoints in c carotid artery and supra-aortic trunk revascularization trials. Catheter Cardiovasc Interv 2010; 76:

6 10. Van der Voort van Zyp NC, Van der Holt B,..., Pattynama PM,, Nuyttens JJ. Stereotactic body radiotherapy using real-time tumor tracking in octogenarians with non-small cell lung cancer. Lung Cancer 2010; 69: Paulides MM, Bakker JF,, Pattynama PM,, van Rhoon GC. The clinical feasibility of deep hyperthermia treatment in the head and neck: new challenges for positioning and temperature measurement. Phys Med Biol 2010; 55: Helderman F, Manoch IJ,, Pattynama PM,, Krams R. Predicting patient-specific expansion of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 2010; 40: Vrolijk JM, van Noord D,..., Pattynama PM, Mensink P. A giant antral ulceration evoked by a rare cause of single-vessel chronic GI ischemia. Gastrointest Endosc 2010; 72: Pattynama PMT. Legal aspects of cross-border teleradiology. Eur J Radiol 2010; 73: Van der Voort van Zyp NC, Prévost JB,, Pattynama PM,, Nuyttens JJ. Quality of life after stereotactic radiotherapy for stage I non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2010; 77: Barry MC, Hendriks JM,, Pattynama PM,, van Sambeek MR. A comparative study of myocardial injury during conventional and endovascular aortic aneurysm repair: measurement of cardiac troponin T and plasma cytokine release. Ir J Med Sci 2010; 179: Wils A,, Pattynama PM. Transjugular intrahepatic portosystemic shunt in patients with chronic portal vein occlusion and cavernous transformation. J Clin Gastroenterol 2009: 10: Van der Linden, Pattynama PM, et al. Long-term patient satisfaction after percutaneous treatment of peripheral vascular malformations. Radiology 2009: 251: Bax L, Woittiez AJ,, Pattynama PM,, Beutler JJ. Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial. Ann Intern Med 2009: 150: Van der Voort van Zyp NP, Prévost JB,, Pattynama PM, Nuyttens JJ. Stereotactic radiotherapy with real-time tumor tracking for non-small cell lung cancer: clinical outcome. Radiother Oncol 2009; 91:

7 21. Spronk S, Bosch JL,, Pattynama PM, Hunink MGM. Intermittent claudication: clinical effectiveness of endovascular revascularization versus supervised hospital-based exercise training a randomized controlled trial. Radiology 2009; 250: Van Buuren, HR, Wils A,, Pattynama PM. Dutch study on the optimal treatment strategy for patients with a first or second occurrence of gastro-esophageal variceal bleeding: the TIPS-TRUE trial. Ned Tijdschr Geneeskunde 2008; 152: Smalberg JH, Spaander MV,, Pattynama PM,, Leebeek FW. Risks and benefits of transcatheter thrombolytic therapy in patients with splanchnic venous thrombosis. Thromb Haemos 2008; 100: Robbers-Visser D, Helderman F,, Pattynama PM,, Helbing WA. Pulmonary artery size and function after Fontan operation at a young age. J Magn Reson Imaging 2008; 28: Spronk S, Bosch JL,, Pattynama PM, Hunink MGM. Cost-effectiveness of endovascular revascularization compared to supervised hospital-based exercise training in patients with intermittent claudication: a randomized controlled trial. J Vasc Surg 2008; 48: Diehm N, Pattynama PM,, Biamino G. Clinical endpoints in peripheral endovascular revascularization trials: a case for standardized definitions. Eur J Vasc Endovasc Surg 2008; 36: Helderman F, Manoch IJ,, Pattynama PM,, Krams R. A numerical model to predict abdominal aortic aneurysm expasion based on local wall stress and stiffness. Med Biol Eng Comput 2008; 46: Van den Berg J, Strengers JL,, Pattynama PM, Helbing WA. Assessment of biventricular functional reserve and NT-proBNP levels in patients with RV volume overload after repair of tetralogy of Fallot at young age. Int J Cardiol 2008; 133: Robbers-Visser D, Ten Harkel DJ,, Pattynama PM,, Helbing WA. Usefulness of cardiac magnetic resonance imaging combined with low-dose dobutamine stress to detect abnormal ventricular stress response in children And young adults after Fontan operation at young age. Am J Cardiol 2008; 101: Van den Berg J, Bannink EM,, Pattynama PM,.., Helbing WA. Cardiac status after childhood growth hormone treatment of Turner syndrome. J Clin Endocrinol Metab 2008; 93:

8 31. Ouwendijk R, De Vries M, Pattynama PM,, Hunink MG. Multicenter randomized controlled trial of the costs and effects of noninvasive diagnostic imaging in patients with peripheral arterial disease: the DIPAD trial. AJR Am J Roentgenol 2008; 190: Prévost JB, Nuyttens JJ, Pattynama PM. Endovascular coils as lung tumour markers in real-time tumour tracking stereotactic radiotherapy: preliminary results. Eur Radiol 2008; 18: Murad SD, Luong TK, Pattynama PM, et al. Long-term outcome of a covered vs. uncovered transjugular intrahepatic portosystemic shunt in Budd-Chiari syndrome. Liver Int 2008;28: Wang L, Bos IC,, Pattynama PM,, Krestin GP. Post-processing of dynamic gadoliniumenhanced magnetic resonance imaging exams of the liver: explanation and potential clinical applications for color-coded qualitative and quantitative analysis. Acta Radiol 2008;49: Zähringer M, Pattynama PM, et al. Drug-eluting stents in renal artery stenosis. Eur Radiol 2008; 18: Kock MC, Dijkshoorn ML, Pattynama PM, et al. Multi-detector row computed tomography of peripheral arterial disease. Eur Radiol 2007; 17: Pattynama PM, et al. Embolization with the Amplatzer plug in TIPS patients. Cardiovasc Intervent Radiol 2007; 30: van den Berg J, de Bie S,, Pattynama PM,, Helbing WA. Changes during exercise of ECG intervals related to increased risk for ventricular arrhythmia in repaired Tetralogy of Fallot and their relationship to right ventricular size and function. Int J Cardiol 2008; 124: Zähringer M, Sapoval M, Pattynama PM, et al. Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT trial): Angiographic follow-up after 6 months and clinical outcome up to 2 years. J Endovasc Ther 2007; 14: Ouhlous M, Moelker A,, Pattynama PM, van der Lugt A. Quadrature coil design for high-resolution carotid artery imaging scores better than a dual phased-array coil design with the same volume coverage. J Magn Reson Imaging 2007; 25: van den Berg J, Wielopolski PA,, Pattynama PM, Helbing WA. Diastolic function in repaired tetralogy of Fallot at rest and during stress: assessment with MR imaging. Radiology 2007; 243:

9 42. van den Berg J, Hop WC,, Pattynama PM,, Helbing WA. Clinical condition at mid-to-late followup after transatrial-transpulmonary repair of tetralogy of Fallot. J Thorac Cardiovasc Surg 2007; 133: Thomeer MG, Pattynama PM, Hartmann IJ, Kieft GJ, van Strijen MJ. High incidence of isolated subsegmental pulmonary emboli on multi-slice spiral CT: a comparative clinical study. Thromb Haemostasis 2006; 95: Nuyttens JJ,, Pattynama PM. Lung tumor tracking during stereotactic radiotherapy treatment with the CyberKnife: marker placement and early results. Acta Oncol 2006; 45: Van der Meer RW, Pattynama PM, et al. Rechter ventrikel dysfunctie en de pulmonale obstructie index: Voorspellers van het klinisch beloop gedurende drie maanden bij patiënten met acute longembolie. Ned Tijdschr voor Geneeskunde 2006; 150: Michiels JJ,, Pattynama PM. Different accuracies of rapid enzyme-linked immunosorbent, turbidimetric, and agglutination D-dimer assays for thrombosis exclusion: impact on diagnostic workups of outpatients with suspected deep vein thrombosis and pulmonary embolism (review). Semin Thromb Hemost 2006; 32: Zindler JD, Hendriks JM,, Pattynama PM,, van Dijk LC. Complications within 30 days following placement of a carotid stent with cerebral protection in patients with considerable symptomatic carotid stenosis: Erasmus MC, Rotterdam, Ned Tijdschr Geneeskd 2006; 150: Sier MF, van Sambeek,, Pattynama PM,, Bosch JL. Shrinkage of abdominal aortic aneurysm after successful endovascular repair: results from single center study. J Cardiovasc Surg (Torino) 2006; 47: Van den Berg J, Bannink EM,, Pattynama PM,, Helbing WA. Aortic distensibility and dimensions and the effects of growth hormone treatment in the turner syndrome. Am J Cardiol 2006;97: Hendriks JM, Zindler JD,, Pattynama PM,, van Dijk LC. Embolic protection filters for carotid stenting: differences in flow obstruction depending on filter construction. J Endovasc Ther 2006; 13: Rotmans JI, Pattynama PM, et al. Sirolimus-eluting stents to abolish intimal hyperplasia and improve flow in porcine arteriovenous grafts. A 4-week follow-up study. Circulation 2005; 111:

10 52. van Strijen MJL, ten Wolde M, Pattynama PM, et al. Diagnostiek bij longembolie ; de beste strategieen volgens de resultaten van een grote Nederlandse multicenterstudie. Ned Tijdschr voor Geneeskunde 2005; 149: van der Meer RW, Pattynama PM, et al. Right ventricular dysfunction and the pulmonary obstruction index assessed with helical CT: Clinical outcome prediction during three-month follow-up in patients with acute pulmonary embolism. Radiology 2005; 253: Spronk S,, Pattynama PM. Value of the duplex wave form at the common femoral artery for diagnosing obstructive aorto-iliac disease. J Vasc Surg 2005: 42: Maksimovic R,, Pattynama PM. Sixteen multidetector row computed tomography of pulmonary veins: 3-months' follow-up after treatment of paroxysmal atrial fibrillation with cryothermal ablation. Eur Radiol 2005; 15: Moelker A,, Pattynama PM. Importance of bone-conducted sound transmission on patient hearing in the MR scanner. J Magn Reson Med 2005; 22: Michiels JJ,, Pattynama PM. A critical appraisal of non-invasive diagnosis and exclusion of deep vein thrombosis and pulmonary embolism in outpatients with suspected deep vein thrombosis or pulmonary embolism: how many tests do we need? Int Angiol 2005;24: Kock MC, Adriaensen ME, Pattynama PM, et al. DSA versus multi-detector row CT angiography in peripheral arterial disease: randomized controlled trial. Radiology 2005; 237: Ouwendijk R, de Vries M, Pattynama PM, et al. Imaging peripheral artery disease: a randomized controlled trial comparing contrast-enhanced MR angiography and multi-detector row CT angiography. Radiology. 2005; 236: Sapoval M, Zähringer M, Pattynama PM, et al. Low-profile stent system for treatment of atherosclerotic renal artery stenosis: the GREAT trial. J Vasc Intervent Radiol 2005; 16: Ouwendijk R, Kock MC,, Pattynama PM,, Hunink MG. Interobserver agreement for the interpretation of contrast-enhanced 3D MR angiography and MDCT angiography in peripheral arterial disease. AJR Am J Roentgenol 2005; 185: van Strijen MJ, Bloem JL,, Pattynama PM,, Antelope-Study Group. Helical computed tomography and alternative diagnosis in patients with excluded pulmonary embolism. J Thromb Haemost 2005; 3:

11 63. Rotmans JI, Pasterkamp G,..., Pattynama PM,..., Stroes ES. Hemodialysis access graft failure: Time to revisit an unmet clinical need? J Nephrol 2005; 18: Ouhlous M, Flach HZ,, Pattynama PM, van der Lugt A. Carotid plaque composition and cerebral infarction: MR imaging study. AJNR Am J Neuroradiol 2005; 26: van Strijen MJ, De Monyé W,, Pattynama PM,, Huisman MV. Accuracy of single-detector spiral CT in the diagnosis of pulmonary embolism: a prospective multicenter cohort study of consecutive patients with abnormal perfusion scintigraphy. J Thromb Haemost 2005; 3: Michiels JJ,, Pattynama PM. Non-invasive diagnosis of pulmonary embolism, anno Acta Chir Belg 2005; 105: Michiels JJ,, Pattynama PM. Screening for deep vein thrombosis and pulmonary embolism in outpatients with suspected DVT or PE by the sequential use of clinical score: A sensitive quantitative D-dimer test and noninvasive diagnostic tools (review). Semin Vasc Med 2005; 5: Kock MC, IJzermans JN,, Pattynama PM, Hunink MG. Contrast-enhanced MR angiography and digital subtraction angiography in living renal donors: diagnostic agreement, impact on decision making, and costs. AJR Am J Roentgenol 2005; 185: Vogel MW,, Pattynama PM. Monitoring tissue coagulation during thermoablative treatment by using a novel magnetic resonance imaging contrast agent. Invest Radiol 2004; 39: Moelker A,, Pattynama PM. Verbal communication in MR environments: Effect of MR system acoustic noise on speech understanding. Radiology 2004; 232: Moelker A,, Pattynama PM. Real-time modulation of acoustic gradient noise in interventional MR imaging. Concepts Magn Reson Part B (Magn Reson Engineering) 2004: 20B: Maksimovic, R,, Pattynama PM. Sixteen-row multislice computed tomography in the assessment of pulmonary veins prior to ablative treatment: validation versus conventional pulmonary venography and study of reproducibility. Eur Radiol 2004; 14: De Feyter P, Mollet N,., Pattynama P, Serruys P. Non-invasive visualization of coronary atherosclerosis with multislice computed tomography. Cardiovasc Radiat Med 2004; 5:

12 74. Barry MC, Hendriks JM,, Pattynama PM,.., van Sambeek MR. Comparison of catecholamine hormone release in patients undergoing carotid artery stenting or carotid endarterectomy. J Endovasc Ther 2004;11: Cademartitri F, Luccichenti G,, Pattynama PM,, Krestin GP. Sixteen-row multislice computed tomography: basic concepts, protocols, and enhanced clinical applications. Semin Ultrasound CT MR 2004; 25: Cademartiri F, Mollet N,, Pattynama PM,, Krestin GP Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser. Eur Radiol 2004: 14: Mollet NR, Cademartiri F,, Pattynama PM,, De Feyter PJ. Multislice spiral CT coronary angiography in patients with stable angina pectoris. J Am Coll Cardiol 2004; 43: Leter EM, Schuurbiers JC,, Pattynama PM,, Slager CJ. A biplane angiographic study on cardiac motion of coronary artery stents: options to minimize the target volume for high-precision external beam radiotherapy of coronary artery in-stent restenosis. Int J Radiat Oncol Biol Phys 2004; 58: Cademartiri F, Nieman K,, Pattynama PM,, Krestin GP. Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique. Radiology 2004; 233: Adriaensen ME, Kock MC,, Pattynama PM, Hunink MG. Peripheral arterial disease: therapeutic confidence of CT versus digital subtraction angiography and effects on additional imaging recommendations. Radiology 2004; 233: Cademartiri F, Raaijmakers RHJM,, Pattynama PM, Krestin GP. Role of multi-detector row CT angiography in patients with abdominal angina. Radiographics 2004; 24: Nieman K, Pattynama PM, et al. Evaluation of patients after coronary artery bypass surgery: CT angiographic assessment of grafts and coronary arteries. Radiology 2003: 229: Moelker A, Pattynama PM. Acoustic noise concerns in functional magnetic resonance imaging. Hum Brain Mapping 2003; 20: Vogel MW, Pattynama PM, et al. Use of fast spin echo for phase shift magnetic resonance thermometry. J Magn Reson Imaging 2003; 18:

13 85. Kuiper JW,, Pattynama PM. Radiation exposure of multi-row detector spiral computed tomography of the pulmonary arteries: comparison with digital subtraction pulmonary angiography. Eur Radiol 2003: 13: Preda A,, Pattynama PM. Complication rate and diagnostic yield of 515 consecutive ultrasoundguided biopsies of renal allografts and native kidneys using a 14-gauge biopty gun. Eur Radiol 2003; 13: van Holten J,, Pattynama PM. Thrombolysis of occluded synthetic bypass grafts in the lower limb: Technical success and 1-year follow-up in 32 patients. J Endovasc Ther 2003: 10: van Strijen MJL,, Pattynama PM. Single-detector helical computed tomography as the primary diagnostic test in suspected pulmonary embolism: a multicenter clinical management study of 510 patients. Ann Intern Med 2003; 138: Moelker A,, Pattynama PM. Efficacy of passive acoustic screening: Implications for the design of imager and MR-suite. J Magn Reson Imaging 2003; 17: Feyter PD,, Pattynama P. MS-CT coronary imaging. J Interv Cardiol 2003;16: Wikstrom J, Wasser MN, Pattynama PM, et al. Gadobenate dimeglumine-enhanced magnetic resonance angiography of the pelvic arteries. Invest Radiol 2003; 38: Moelker A, Wielopolski P, Pattynama PM. Relationship between magnetic field strength and magnetic-resonance-related acoustic noise levels. Magn Reson Mater Phys Biol Med MAGMA 2003: 16: Michiels JJ,, Pattynama PM. Non-invasive exclusion and diagnosis of pulmonary embolism by sequential use of the rapid ELISA D-dimer assay, clinical score and spiral CT. Int Angiol 2003; 22: Renken NS, Wittens CH, Pattynama PM, et al. Open surgical versus minimally invasive in situ femorodistal bypass: long-term results. J Endovasc Ther 2003; 10: Nieman K, Cademartiri F,, Pattynama P, De Feyter P. Noninvasive angiographic evaluation of coronary stents with multi-slice spiral computed tomography. Herz 2003;28: Nieman K, van der Lugt A, Pattynama PM, de Feyter PJ. Noninvasive visualization of atherosclerotic plaque with electron beam and multislice spiral computed tomography. J Interv Cardiol 2003;16:

14 97. van Holten J, Wielopolski P,, Pattynama PM, van Dijk LC. High flip angle imaging of metallic stents: Implications for MR angiography and intraluminal signal interpretation. Magn Reson Med 2003; 50: Verhoef C, Kuiper JW,, Pattynama PM, IJzermans JN. Interstitial laser coagulation with temporary hepatic artery occlusion for patients with cirrhosis and irresectable hepatoma. Br J Surg 2003; 90: van Strijen, MJL, de Monyé W,, Pattynama PM,, Bloem JL. Diagnosis of pulmonary embolism with spiral CT as a second procedure following scintigraphy. Eur Radiol 2003; 13: Hussain SM, Kock MC,, Pattynama PM,, Krestin GP. MR imaging: a "one-stop shop" modality for preoperative evaluation of potential living kidney donors Radiographics 2003; 23: Bax L, Mali WP,., Pattynama PM,, STAR Study Group. The benefit of STent placement and blood pressure and lipid-lowering for the prevention of progression of renal dysfunction caused by Atherosclerotic ostial stenosis of the Renal artery. The STAR-study: rationale and study design. J Nephrol 2003;16: Moelker A,, Pattynama PM. Acoustic noise is a potential occupational hazard in interventional MRI: Quantification of sound exposure during interventional MRI at 1.5T. Radiology 2002; 224: Hartmann IJ,, Pattynama PM. Optimal scan delay in spiral CT for the diagnosis of acute pulmonary embolism. J Comput Assist Tomogr 2002; 26: Michiels JJ,, Pattynama PM. The rehabilitation of clinical assessment for the diagnosis of pulmonary embolism (review). Semin Vasc Med 2002; 2: Gill-Leertouwer TC,, Pattynama PM. Predictors for clinical success at one year following renal artery stent placement. J Endovasc Ther 2002; 9: Gill-Leertouwer TC,, Pattynama PM. Shrinkage of the distal renal artery 1 year after stent placement as evidenced with serial intravascular ultrasound. Br J Radiol 2002; 75: Kroencke TJ, Wasser MN, Pattynama PM, et al. Gadobenate dimeglumine-enhanced MR angiography of the abdominal aorta and renal arteries. AJR Am J Roentgenol 2002;179:

15 108. Leertouwer TC, Derkx FHM, Pattynama PM, et al. Effect of stent placement for renal artery stenosis on the function of the treated and contralateral kidneys. Kidney Int 2002; 62: Maes RM, Matheijssen NA, Pattynama PM, et al. Magnetic resonance angiography by gasses or gas-containing agents: first developments of new types of black blood imaging. Acad Radiol 2002; Suppl 2:S van Holten J, Kunz P,, Pattynama PM,, van Dijk LC. MR-velocity mapping in vascular stents to assess peak systolic velocity. In vitro comparison of various stent designs made of stainless steel and nitinol. Magn Reson Mater Phys Biol Med MAGMA 2002; 15: de Monyé W, Sanson BJ,, Pattynama PM,, Huisman MV. Embolus location affects the sensitivity of a rapid quantitative D-dimer assay in the diagnosis of pulmonary embolism. Am J Respir Crit Care Med 2002; 165: De Monyé W, Sanson BJ,, Pattynama PM, Huisman MV. The performance of two rapid quantitative D-dimer assays in 287 patients with clinically suspected pulmonary embolism. Thromb Res 2002;107: Nieman K, Cademartiri F,, Pattynama PM, De Feyter PJ. Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation 2002; 106: van Sambeek MRHM, van Dijk LC,, Pattynama PM, van Urk H. Endovascular versus conventional open repair of acute abdominal aortic aneurysm: feasibility and preliminary results. J Endovasc Ther 2002; 9: Nieman K, Rensing BJ,, Pattynama PM,, de Feyter PJ. Non-invasive coronary angiography with multislice spiral computed tomography: impact of heart rate. Heart 2002; 88: Ouhlous M, Lethimonnier F,, Pattynama PM, van der Lugt A. Evaluation of a dedicated dual phased-array surface coil using a black-blood FSE sequence for high resolution MRI of the carotid vessel wall. J Magn Reson Imaging 2002; 15: Nieman K, Rensing BJ,, Pattynama PM,, de Feyter PJ. Usefulness of multislice computed tomography for detecting obstructive coronary artery disease. Am J Cardiol 2002; 89: Hagenaars T, A Po IF,, Pattynama PM, Gussenhoven EJ. Gamma radiation induces positive vascular remodeling after balloon angioplasty: A prospective, randomized intravascular ultrasound scan study. J Vasc Surg 2002; 36:

16 119. Leertouwer TC, Pattynama PM, et al. Incidental renal artery stenosis in peripheral vascular disease: A case for treatment? Kidney Intern 2001; 59: De Monyé W, Pattynama PM. Contrast-enhanced spiral computed tomography of the pulmonary arteries an overview. Semin Thromb Hemost 2001; 2001; 27: Wagenaar HC,, Pattynama PM. Tumor diameter and volume assessed by magnetic resonance imaging in the prediction of outcome of invasive cervical cancer. Gynecol Oncol 2001; 82: Pattynama PM, et al. Second-generation, subsecond multislice computed-tomography: Advancing the role of helical CT pulmonary angiography in suspected pulmonary embolism. Semin Vasc Med 2001; 1: van Dijk LC,, Pattynama PM. A precious metal alloy for construction of MR imaging compatible balloon-expandable vascular stents. Radiology 2001; 219: Hagenaars T, Gussenhoven EJ,, Pattynama PM, van Sambeek MRHM. Intravascular ultrasound evidence for stabilization of compensatory enlargement of the femoropopliteal segment after endograft placement. J Endovasc Ther 2001; 8: Postema S, Pattynama PM, et al. Effect of MRI on therapeutic decisions in invasive cervical carcinoma: Direct comparison with the pelvic examination as a pre-operative test. Gynecol Oncol 2000; 79: Heisterkamp J, van Hillegersberg R,, Pattynama PM, IJzermans JNM. Behandeling van patienten met irresectabele tumoren in de lever door middel van percutane interstitiele lasercoagulatie tijdens onderbreking van de bloedstroom naar de lever. Ned Tijschr voor Geneeskunde 2000; 144: Michiels JJ, Pattynama PM. Exclusion and diagnosis of pulmonary embolism by a rapid ELISA D- dimer test and noninvasive imaging techniques within the context of a clinical model. Clin Appl Thromb Hem 2000: 6: De Monyé W,, Pattynama PM. Suspected pulmonary embolism: prevalence and anatomic distribution in 487 consecutive patients. Radiology 2000; 215: Maes RM, Matheijssen NAA, Pattynama P, et al. The use of carbon dioxide in magnetic resonance angiography: a new type of black blood imaging. J Magn Reson Imaging 2000; 12:

17 130. Postema S, Pattynama PM, et al. Cervical carcinoma: can dynamic contrast-enhanced MR imaging predict tumor aggressiveness? Radiology 1999; 210: van Erkel AR, Pattynama PM. The role of spiral computed tomography in the assessment of patients with suspected pulmonary embolism. Clin Appl Thromb Hem 1999; 5: Leertouwer TC,, Pattynama PM. Intravascular ultrasound evidence for renal artery coarctation causing symptomatic renal artery stenosis. Circulation 1999; 99: van Dijk LC,, Pattynama PM. Ultrasound guided percutaneous coil embolisation of incompetent perforating veins: not effective for treatment of venous ulcers and recurrent varicosis. J Vasc Interv Radiol 1999; 10: De Monyé W,, Pattynama PM. Observer dependency of the SimpliRed D-dimer assay in 81 consecutive patients with suspected pulmonary embolism. Thromb Res 1999; 96: van Erkel AR,, Pattynama PM. International differences in health-care costs in Europe and the United States; do these affect the cost-effectiveness of diagnostic strategies for pulmonary embolism? Eur Radiol 1999; 9: Westenberg JJM, Wasser MNJM,, Pattynama PM,, Reiber JHC. Gadolinium contrastenhanced three-dimensional MRA of peripheral arteries with multiple bolus injections: scan optimization in-vitro and in-vivo. Int J Card Imaging 1999; 15: Pijl MEJ,, Pattynama PM. Liver rupture after transcatheter arterial chemoembolization of a giant hepatocellular carcinoma: a case report. J Vasc Interv Radiol 1999; 10: Westenberg JJM, van der Geest RJ,, Pattynama PM,, Reiber JHC. Stenosis quantification from post-stenotic signal loss in phase-contrast MRA datasets of flow phantoms and renal arteries. Int J Card Imaging 1999; 15: Jerzewski A, Steendijk P, Pattynama PM, et al. Right ventricular systolic function and ventricular interaction during acute embolization of the left anterior descending coronary artery in sheep. Cardiovasc Res 1999; 43: Westenberg JJM, Wasser MNJM,, Pattynama PM,, Reiber JHC. Scan optimization of gadolinium contrast-enhanced three-dimensional MRA of peripheral arteries with multiple bolus injections and in-vitro validation of stenosis quantification. Magn Reson Imaging 1999; 17:

18 141. Jerzewski A, Pattynama PM, et al. Differential response of the right and left ventricle to β-adrenergic stimulation: an echo planar MR study in intact animals. J Comput Assist Tomogr 1998; 22: van Rossum AB, Pattynama PM, et al. Spiral CT appearance of resolving clots at six weeks followup after acute pulmonary embolism. J Comput Assist Tomogr 1998; 22: (The article received the journal s 1998 Giovanni DiChiro award for outstanding scientific research) Postema S, Pattynama PM, et al. Staging of uterine cervical carcinoma: comparison between fast spin-echo MRI and GRASE. Eur Radiol 1998; 8: Postema S, Pattynama PM, et al. Fast dynamic contrast-enhanced colour-coded MRI in uterine cervix carcinoma: useful for tumour staging? Clin Rad 1998; 53: van Erkel AR, Pattynama PM. Cost-effective diagnostic algorithms in pulmonary embolism: an updated analysis. Acad Radiol 1998, 5(S): van Rossum AB, Pattynama PM, et al. Can helical CT replace scintigraphy in the diagnostic process in suspected pulmonary embolism? A retrolective-prolective cohort study focusing on total diagnostic yield. Eur Radiol 1998; 8: van Rossum AB,, Pattynama PM. Accuracy of helical CT for acute pulmonary embolism: ROCanalysis of observer performance related to clinical experience. Eur Radiol 1998; 8: van Rossum AB,, Pattynama PM. Prevalence of deep vein thrombosis in suspected and proven pulmonary embolism: a meta-analysis. Br J Radiol 1998; 71: van Erkel AR, Pattynama PM. Receiver operating characteristic (ROC) analysis: basic principles and application in radiology. Eur J Radiol 1998; 27: Westenberg JJM, van der Geest RJ,, Pattynama PM,, Reiber JHC. Objective stenosis quantification from post-stenotic signal loss in phase-contrast magnetic resonance angiographic datasets of flow phantoms and renal arteries. Magn Reson Imaging 1998; 16: Westenberg JJM, van der Geest RJ,, Pattynama PM,, Reiber JHC. Variations in blood flow waveforms in stenotic renal arteries by 2D-phase-contrast cine MRI. J Magn Reson Imaging 1998; 8: Wasser MN,, Pattynama PM. Hemodynamic significance of renal artery stenosis: digital subtraction angiography versus systolically gated three-dimensional phase-contrast MR angiography. Radiology 1997; 202:

19 153. van Rossum AB, Pattynama PM, et al. Spiral CT angiography for pulmonary embolism: validation in 149 patients. Radiology 1996; 201: Waldman GJ, Pattynama PM, et al. Magnetic resonance angiography of dialysis access shunts: Initial results. Magn Reson Imaging 1996; 14: Jerzewski A, Pattynama PM, et al. Development of an MRI compatible catheter for pacing the heart: initial in-vitro and in-vivo results. J Magn Reson Imaging 1996; 6: Overbosch EH, Pattynama PM, et al. Occluded dialysis shunts: Dutch multicenter experience with the Hydrolyser catheter. Radiology 1996; 201: van Erkel AR,, Pattynama PM. Spiral CT angiography for suspected pulmonary embolism: a costeffectiveness analysis. Radiology 1996; 201: Postema S,, Pattynama PM. Uterine cervix carcinoma: do fast SE and fat suppression techniques improve MR tumor staging at.5t? J Comput Assist Tomogr 1996; 20: van der Hulst VPM,, Pattynama PM. Renal artery stenosis: endovascular flow wire study for validation of Doppler US. Radiology 1996; 200: De Berg JC, Pattynama PM, et al. Percutaneous computed-tomography-guided thermocoagulation for osteoid osteomas. Lancet 1995: 346: Tjin A Ton ER, Pattynama PM, et al. Device for applying ulnar and radial stress in MR imaging of the wrist. Radiology 1995; 196: Hoogendoorn LI, Pattynama PM, et al. Noninvasive evaluation of aortocoronary bypass grafts with magnetic resonance flow mapping. Am J Cardiol 1995; 75: Pattynama PM, et al. Revascularization of occluded haemodialysis fistulas with the Hydrolyser thrombectomy catheter. Description of the technique and report of six cases. Nephrol Dial Transplant 1995: 10: Pattynama PM, et al. Inadvertent arteriovenous stenting during transjugular intrahepatic portosystemic shunt procedure and the importance of hepatic artery perfusion. Cardiovasc Intervent Radiol 1995; 18:

20 165. Pattynama PM, et al. Magnetic resonance imaging analysis of left ventricular pressure-volume relations: Validation with the conductance method at rest and during dobutamine stress. Magn Reson Med 1995; 34: Pattynama PM, et al. Reproducibility of MRI-derived measurements of right ventricular volumes and myocardial mass. Magn Reson Imaging 1995; 13: Pattynama PM, et al. Percutaneous angioplasty for atherosclerotic renal artery disease: Effect on renal function in azotemic patients. Cardiovasc Intervent Radiol 1994, 17: Pattynama PM, et al. Evaluation of cardiac function with magnetic resonance imaging. Am Heart J 1994; 128: Pattynama PM, et al. Cardiovascular MR imaging: Pressure-gating using the arterial pressure from a conventional ferromagnetic micromanometer-tip catheter. Magn Reson Imaging 1994; 12: Oudenhoven LFIJ, Pattynama PM, et al. Magnetic resonance, a new method for measuring blood flow in hemodialysis fistulae. Kidney Intern 1994; 45: Pattynama PM, et al. Left ventricular measurements by cine and spin-echo MR imaging: A study of reproducibility with variance component analysis. Radiology 1993; 187: Pattynama PM, et al. MR evaluation of left ventricular function: Effect of through-plane motion. Invest Radiol 1992; 27: De Roos A, Doornbos J,, Pattynama PM, van der Wall EE. Cardiovascular applications of magnetic resonance imaging and phosphorus-31 spectroscopy. Eur J Radiol 1992; 14: Pattynama PM, et al. Early diagnosis of cor pulmonale by MR imaging of the right ventricle. Radiology 1992; 182:

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