Copyright 2011 Penguin Computing, Inc. All rights reserved. Interactive Preclinical Analytics via GPU Cloud Platform
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1 Copyright 2011 Penguin Computing, Inc. All rights reserved Interactive Preclinical Analytics via GPU Cloud Platform
2 Numira and Penguin Partnership Penguin POD Innovative HPC as a Service platform > Strong Life Sciences business > Proven models for delivery of SaaS on parallel platforms Numira Groundbreaking imaging technologies > Medical imaging as a biomarker: rich analytics > Cloud-based delivery of data, analytics, and collaboration Results for Numira customers > Globally available advanced pre-clinical imaging services > Faster, more detailed and expressive imaging capabilities > Ease of utilization, collaboration and communication tools Copyright 2011 Penguin Computing, Inc. All rights reserved 2
3 Penguin provides Linux HPC Solutions Linux Systems Servers Workstations Cluster Management Software HPC as a Service - Penguin on Demand Professional Services and Engineering HPC Clusters Storage Optimized for Linux Ease of Management Elastic Computing Linux and Cluster Expertise Intel & AMD Rackmount Servers Storage Networking Infrastructure GPGPUs Professional Workstations Scyld ClusterWare Scyld TaskMaster Enterprise Linux Compilers & Tools On-demand environment HPC optimized Tiered Pay-asyou-go pricing Premium set-up and support services Factory Integration Onsite Installation Training Product Support Software Support Customized Service Engagements Copyright 2011 Penguin Computing, Inc. All rights reserved 3
4 POD Platform On-demand HPC system > Compute, storage, low latency fabrics, GPU, non-virtualized Robust software infrastructure > Full automation Internet (150Mb, burstable to 1Gb) > User and administration space controls > Secure and seamless job migration > Extensible framework > Complete billing infrastructure Services > Custom product design > Site and workflow integration > Managed services > Application support HPC support expertise > Skilled HPC administrators > Leverage 13 yrs serving HPC market Copyright 2011 Penguin Computing, Inc. All rights reserved 4
5 POD GPU Offering Base GPU server configuration > 8 core, 2.6GHz Nehalem servers > 24 GB RAM (DDR3-1333) Dual C2075 NVIDIA Tesla GPUs > Number of processor cores: 448 > Processor core clock: 1.15 GHz > PCI Express Gen2 16 system interface > Memory clock: 1.50 GHz > Memory Interface: 384-bit 6GB 24 pieces 64M 32 GDDR5 136-pin BGA, SDRAM Full GPU management integrated into POD stack $2.25 per server hour (volume discounts available) Typical applications: > NVIDIA RealityServer > Reverse Time Migration > MatLab > NAMD > custom applications Copyright 2011 Penguin Computing, Inc. All rights reserved 5
6 POD Genesis Increasing customer needs for on-demand resource > Hybrid, Overflow, Workload-specific Growth for HPC in non-expert user base Increased demand for research collaboration platforms Strong cluster software platform Low cost of goods as HPC systems manufacturer Clear vision of product requirements for market Broad customer base across Enterprise, Fed, EDU Strong HPC expertise Copyright 2011 Penguin Computing, Inc. All rights reserved 6
7 Penguin HPC Cloud Services On-Demand HPC Cloud Hybrid Cloud (burst-out) Private HPC Cloud Scyld Cloud Management System (coming late 2012) Post-Purchase Collocation Turnkey Remote Managed Services True HPC in the cloud on a pay-as-you-go basis, rate varies by commitment (hourly, monthly, annual) Penguin clusters with workflow migration to POD, or included POD usage ( tools and services provided as PS) OEM or Penguin partnership to provide a dedicated cloud to a target group of customers Software system to operate and manage a highly secure HPC cloud system Collocation services at our Salt Lake City Data Center Same remote system management services that we use for POD, provided to our customers! Copyright 2011 Penguin Computing, Inc. All rights reserved 7
8 POD Automation Portal System 2 releases Q2, 2012 POD Portal User User Portal Login/register View/download billing and usage Portal access to Login VMs Save/manage custom Login VMs Create/manage groups Request cluster configurations Launch and manage jobs Monitor cluster usage Monitor job progress /home iscsi Targets /store/[username] Application User Head Node Compute Node Compute Node Compute Node Direct login: ssh scp rsync User Facing Application Virtual Login Node VLAN Compute Node Compute Node Copyright 2011 Penguin Computing, Inc. All rights reserved 8
9 Numira focuses on pre-clinical drug development & the pain points that prevent rapid, confident decisions Numira Pain Points Testing methods that are years old The immense amount of data being generated 9
10 Virtual Histology TM Leader in high-resolution, 3D quantitative imaging Birth Defects Brain / Vasculature Atherosclerosis Heart Defects Ophthalmology Arthritis Lung / Oncology Renal 10
11 Pain Point: Current Manual Methods Example: Osteoarthritis Problem: Methods are years old Time consuming & inaccurate Razor blades & microscope slides Disease is routinely missed Requires many animals Subjective results weeks Destructive Numira s Solution: Virtual Histology TM 2,000 digital, 3D slices of whole joint Reproducible, quantitative results o Linear o Volume o Thickness o Roughness o Changes to bone Significant cost reduction o Fewer animals o 5 6 weeks to finish Non-Destructive Interactive datasets Microscope slide with a vertical slice of a rat knee joint. 11
12 AltaPortal TM Cloud / SaaS solution for a large, unmet need Manage immense amount of data 1,500+ Pharma and Biotech companies 6,000+ drugs under development Multiple imaging studies per drug Dozens to hundreds of images per study File sizes 1GB - 20GB per image Access to Numira s analytical tools Fill the communication void Rapid scale-up with multiple channel partners Microsoft partnership in place Others in process It s easier to repeat a study than find and mine data from a previous study. - Senior researcher at a Top 5 pharma 12
13 Services Technologies AltaPortal TM Encrypted Data Storage Study Data Imaging Data Meta-Data Servers (Private or Hosted) Analytics Statistical Visual Integration Other Study Data Third party Apps Other Databases Communication Annotation Collaboration Notification Filter & Search Galleries & enotebooks Whiteboards & Chats Dashboards & Tracking Authenticated & Secure Network Communication Standard Web Browser Smart Phone / Tablet (custom interface) Clients (HTML5) Third party Applications (via API) 13
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