STATE OF THE ART INVITATION SATURDAY, JANUARY 30 TH, 2016 COMORBIDITIES AND ENVIRONMENTAL FACTORS INFLUENCING MULTIPLE SCLEROSIS
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1 18 TH STATE OF THE ART SYMPOSIUM of the Swiss Multiple Sclerosis Society INVITATION SATURDAY, JANUARY 30 TH, 2016 KKL Luzern, Culture and Convention Centre COMORBIDITIES AND ENVIRONMENTAL FACTORS INFLUENCING MULTIPLE SCLEROSIS
2 18 TH STATE OF THE ART SYMPOSIUM OF THE SWISS MULTIPLE SCLEROSIS SOCIETY Dear colleagues, On behalf of the Swiss Multiple Sclerosis Society and its Scientific Advisory Board it is our pleasure to invite you to the 18 th State of the Art Symposium. Recent epidemiological studies demonstrate that in addition to genetic factors environmental factors influence susceptibility to Multiple Sclerosis (MS) and might additionally influence the disease course. The plenary morning session of the 18 th State of the Art Symposium entitled «Comorbidities and Environmental Factors influencing Multiple Sclerosis» is thus to a large degree dedicated to this topic. Four internationally well-known experts have accepted our invitation and will present recent advances in this field. Tomas Olsson will highlight how environmental factors in combination with MS risk genes might influence MS in individual patients. Matthias Mehling will address the effects of immunomodulatory therapies on vaccinations in MS patients, but also touch upon the risk of developing MS following a vaccination. In addition Kerstin Hellwig will report on the influence of pregnancy and oestrogens, while Joost Smolders will discuss the role of vitamin D on the course of MS. The morning will continue with an update on the Swiss MS Registry and the Swiss Cohort Study provided by Viktor von Wyl and Jens Kuhle, and will conclude with a presentation of Ludwig Kappos on the changing treatment algorithms of MS integrating the new drugs on the market. The afternoon session, with two sets of two parallel workshops, will bring to discussion topics relevant in daily practice. The speakers will show the Impact of PML Risk in the treatment of MS (workshop A), explain the benefit of Biomarkers in MS disease course and treatment personalization (workshop B), highlight agents that might promote Neuroprotection (workshop C) and discuss the relevance of measuring Brain Atrophy in clinical practice (workshop D). Updated information about the Symposium can be found on where you may also register for the event. In the name of the organisers and speakers, we sincerely hope that the programme meets with your interest. We cordially invite you to attend the 18 th State of the Art Symposium and to actively take part in the discussions. We look forward to seeing you in Lucerne. Prof. Dr. Britta Engelhardt President of the Scientific Advisory Board Patricia Monin Director of the Swiss MS-Society
3 PROGRAMME Saturday, January 30 th, 2016, KKL Luzern Chairpersons Session I: Prof. Britta Engelhardt, Bern PD Dr. Myriam Schluep, Lausanne Session II: Prof. Nicole Schaeren-Wiemers, Basel Prof. Renaud Du Pasquier, Lausanne Welcome with Coffee and Gipfeli Patricia Monin, Zurich CH Welcome from the Swiss MS-Society Prof. Tomas Olsson, Stockholm SE Lifestyle Factors in MS Interactions with MS Risk Genes Dr. Matthias Mehling, Basel CH MS and Vaccinations PD Dr. Kerstin Hellwig, Bochum DE Pregnancy and Oestrogens Coffee Break Dr. Joost Smolders, Nijmegen NL Environmental Factors Vitamin D Dr. Viktor von Wyl, Zurich and PD Dr. Jens Kuhle, Basel CH Swiss MS Registry and Swiss Cohort Study Prof. Ludwig Kappos, Basel CH New Drugs and changing Treatment Algorithms Lunch Workshops A and B Coffee Break Workshops C and D Farewell Apero
4 WORKSHOPS Saturday, January 30 th, 2016, KKL Luzern Clinical Case Management These workshops focus on aspects relevant to the daily management of MS patients. Attendees are encouraged to submit their own cases by January 18 th, 2016 to or to the workshop speakers Workshop A Impact of PML Risk in the Treatment of MS Prof. Tobias Derfuss, Basel and Dr. Christian Kamm, Bern Overview on PML (what it is, incidence in the population, diseases/treatments in which it may occur) Current status on PML-infection with MS drugs Guidelines on how to manage the risk of PML Workshop B Biomarkers in MS Prof. Andrew Chan, Bochum/Bern and PD Dr. Jens Kuhle, Basel Overview on commonly used biomarkers MRI, CSF, blood Explanation of biomarkers for disease course Explanation of biomarkers for individualized benefit risk stratification strategies and treatment «personalization» Current research status; difficulties in the translation to practice Coffee Break Workshop C Neuroprotection: what is in the Pipeline? Prof. Roland Martin, Zurich and Prof. Caroline Pot, Lausanne Explanation of the mechanisms of the «degenerative» aspects of MS, and how neuroprotection can be achieved Discussion of substances that are approved for other indications and have already shown promise as neuroprotective agents in MS Outlook on approaches that are being pursued for future therapies Workshop D Brain Atrophy in Clinical Practice: useful or nonsense? Dr. Cristina Granziera, Lausanne and Dr. Sven Schippling, Zurich Current evidence of the clinical relevance of brain/spinal cord atrophy measurements in MS Methods currently being used to quantify brain volume changes Discussion of the pros and cons of providing atrophy metrics to neurologists Necessary steps to render atrophy measurements clinically «useful» in the near future Farewell Apero
5 GENERAL INFORMATION Venue KKL Luzern, Europaplatz 1, CH-6005 Lucerne Date Saturday, January 30 th, 2016, 10 am - 4 pm Programme committee Britta Engelhardt, Bern; Claudio Gobbi, Lugano; Tobias Derfuss, Basel; Christian Kamm, Bern; Patrice Lalive, Geneva; Renaud Du Pasquier, Lausanne Organisation Swiss MS-Society and its Scientific Advisory Board Registration Online: symposium@multiplesklerose.ch Fax: Credits Credits will be published on Swiss MS-Society, Josefstrasse 129, CH-8031 Zurich phone , fax , postal account info@multiplesklerose.ch,
6 Public transport The Symposium venue is only a few steps from the SBB Mainstation. Vierwaldstättersee Seebrücke KKL Zentralstrasse Pilatusstrasse SBB Mainstation Kindly supported by
7 REGISTRATION Saturday, January 30 th, 2016, KKL Luzern I will attend the lectures and workshops. I will only attend the lectures. I will not be able to attend the 18 th State of the Art Symposium, please send me the abstract book Workshop A Workshop B Workshops A, B Impact of PML Risk in the Treatment of MS Biomarkers in MS Workshop C Workshop D Workshops C, D Neuroprotection: what is in the Pipeline? Brain Atrophy in Clinical Practice: useful or nonsense? Name Address Phone I would like to receive the Infoletter of the Swiss MS-Society.
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