1 What is Medical Informatics? Sanda Harabagiu Human Language Technology Research Institute DEPARTMENT OF Computer Science
2 Erroneous opinions and misconceptions There is great confusion regarding the definition of Medical Informatics. Often used to describe a broad range of intertwined disciplines Involving all of medical computing and any related disciplines. Let us trace the genesis of the term and the discipline of Medical Informatics
3 Claude Shannon Father of Information Technology
4 Shannon s work
5 Origin of Medical Informatics Field of Medical Informatics is >30 years Origins of general discipline of informatics traced to a Russian publication Oznovy Informatiki (Foundations of Informatics) 1968
6 Origin of Medical Informatics Concept of information science was described within context of an emerging computer age. Focussed on structure and effects of medical information NOT the electronic scaffolding necessary to shuttle the electronic signals to and fro.
7 OED Definition Informatics is the discipline of science which investigates the structure and properties of scientific information 1976 Oxford English Dictionary (Collen,1996) Thus, medical informatics is the discipline which investigates the structure and properties of medical information.
8 Medical Informatics Discipline Medical Informatics recognized as a discipline presumably in st described in document: Education in Informatics of Health Personnel (1974). Although this is the earliest this discipline was given a name, informatics principles date much earlier.
9 Dr Roget Scottish surgeon Devised novel method of representing knowledge on the principle that: All things are concepts Concepts could be described by terms Different terms that described the same concept were called synonyms Developed thesaurus to address problem of synonymy Roget s Thesaurus of English Words and Phrases 1852
10 Dr John Shaw Billings Surgeon General of Army Founding editor of Index Medicus Established National Library of Medicine 1 st director of NLM in 1887
11 Dr John Shaw Billings Dr. Billings was charged with tabulating the U.S. census Devised specific methods of information storage and data manipulation 1890 Conceptualized the genesis of information revolution Described electromechanical device that would tabulate census automatically through punch cards.
12 Herman Hollerith Govt statistician Given job of making this concept a reality Constructed punch-card tabulating machine 56 Hollerith machines were used in 1890 Processed census information for 62 m. people Completed 2 years ahead of schedule! $5 million under budget!!
13 Herman Hollerith Hollerith left government job in 1896 Establish International Tabulating Machines Became International Business Machines (IBM); a.k.a. Deep Blue in 1924 (Collen,1986).
14 Evolution of IBM Logo
15 National Library of Medicine 1887 Dr John Shaw Billings established and became 1 st director of NLM. 1 st stacks of NLM were his personal medical library donations
16 NLM 1887
17 MEDLINE / MEDLARS Dr. Billings work intersected technology again in 1966 Computerization of Index Medicus The resulting system known as MEDLARS 1 st publicly accessible online information system. Today, such systems are ubiquitous in many aspect of our lives
18 MEDLINE / MEDLARS
19 Medical Informatics comes of age Formalization of Medical Informatics discipline from 1974 through 1990 s into new millennium Medical Informatics became increasingly recognized as an important component of the overall practice of medicine (Collen,1996).
20 Shortliffe and Perrault Defined Medical Informatics thus in 1990:..the rapidly advancing scientific field that deals with the storage, retrieval, and optimal use of biomedical information, data, and knowledge for problem solving and decision making. (Shortliffe and Perrault,1990)
21 Shortliffe s definition Shortliffe s definition made no mention of computers or information technology Focussed on subject matter Information, rather than tool Computer. Medical informatics is about information capture, use, and storage rather than equipment that makes it possible
22 Hardware / software However, understanding relationships and properties of information is as important to medical computing as hardware / software necessary for its distribution. This is vital to understanding the field of Medical Informatics and how it will impact medical computing in the future.
23 Medical Informatics Revised concept Next slide shows Edward H. Shortliffe describing the inter-relationships between: biomedical and clinical informatics clinical practice and clinical informatics computer science and biomedical informatics (Amsterdam, 2007)
25 Define Medical Informatics Systematic study Deals with all forms of data Biological data Medical data Associated data Problem solving Decision making
26 Define Medical Informatics Medical informatics is a scientific/systematic field of study that deals with the acquiring, storage, retrieval, and processing of medical, biological and associated data, information and knowledge for the purpose of problem solving and decision making
27 Data, Information, Knowledge Data are the raw facts obtained by processing EMRs Information is outcome of analyzing data Knowledge is obtained from analyzing information and representing it in OBO Foundry ontologies
28 Computerized Medical Records Computer-Aided Instruction Medical Software Security Veterinary Informatics Telemedicine Policy Making Medical Informatics Nursing Informatics Physician Order Entry Systems Medical Expert Systems Medical Software Engineering Clinical Information Systems Health Information Networks
29 Why Medical Informatics Why is proper management of medical data important? Patient health record Administrative purposes Research and knowledge discovery Legal issues And the list goes
30 Why Medical Informatics What is lacking in the current approach? Organizational Logistical Research Passive nature of EMRs
31 Medical Informatics Solutions Databases of EMRs Information Retrieval for Patient Cohort Identification Internet-based access Computer programs developed for processing clinical data
32 Why Medical Informatics What is lacking in the current paper-based approach? onpinews/newsitem.aspx?recordid= Medication errors: Patient has allergic reactions Wrong medication given to patient Wrong dosage given to patient
33 Progress of Medical Informatics Many Medical Informatics research centres developed computerized medical record systems Incorporating Medical Informatics design principles. With the shift to clinician-driven designs Many of these survived today and others are making a resurgence
34 HELP system is an example Developed by University of Utah Deployed in LDS Hospital in Salt Lake City. HELP System
35 Other Systems Other examples of Medical Informatics groups developing medical computing systems include: TMR (The Medical Duke University Regenstrief Medical Record University of Indiana.
36 Regenstrief System The Regenstrief system Contains >1.5 million patient encounters in digital format One of the most extensive repository of medical record information in the world (MacDonald, 1997)
37 Modernization of NLM 1986 Dr. Don Lindberg (pathologist) became director of NLM and ushered in a new era in Medical Informatics NLM began emerging as a staunch supporter of discipline of and research in Medical Informatics This period saw emergence of Medical Informatics in USA
38 Dr. Don Lindberg Led NLM through major changes Development of Unified Medical Language System (UMLS) in 1986 Refinement of MEDLINE Establishment of Visible Human Project (Male / Female) Secured funding of numerous Internet connections to rural hospitals
39 UMLS Meta-thesaurus It is a medical component of a large vocabulary system It addresses need for standardized medical vocabulary Such vocabulary necessary for categorizing biomedical information sources In order to enhance information retrieval UMLS also popular as a vocabulary for computerized medical systems. (NLM,1997).
40 UMLS Meta-thesaurus Based on Roget s original methodology Roget s Thesaurus concept provided a scalable system that addressed differences in concept descriptions (synonymy) encountered in medicine UMLS Meta-thesaurus: Massive project Encompasses >500,000 terms / 252,000 concepts
41 Future of Medical Informatics Medical computing has contributed significantly to improvements in healthcare There are still tremendous challenges for future medical informaticians It is often assumed benefits of a paperless record will be immediately realized once all information available on paper is digitized. However
42 Shortliffe s study Shortliffe s study 168 consecutive visits to an Internal Medicine clinic Those with missing charts, reports were excluded from study Among the remainder, despite having complete medical chart, all laboratory, radiology reports etc In 81% of physician visits, some important information was not available.
43 Shortliffe s study The required information had not been captured in the process of generating the standard medical record This problem is unlikely to be solved by digitizing paper-based information resources already available to physicians. It is an information problem, not a computer problem.
44 Other studies Workgroup for Electronic Data Interchange (WEDI) study found 50% of paper-based medical records are missing or incomplete WEDI, Institute of Medicine (IOM) reported 30% of treatment orders were not documented IOM, 1996.
45 Barriers These are problems of information acquisition They require intimate knowledge of: Information content Environment in which they are collected Technology used to capture them These are essential tools of medical informatician
46 Summary Medical Informatics discipline is not new Yet appears to only be in its infancy in terms of enhancing medical practice Medical Informatics has the potential to benefit patient care as much as a newly discovered drug / therapy Yet direct benefits will not come in classic form therapeutic interventions.
47 Summary Instead, they will be derived from enhancing our ability to care for patients Through improved delivery of medical knowledge and information. This is the promise of Medical Informatics It will be evident as medical practice forges ahead in the information age.
48 Summary Medical Informatics promises to Reduce medical risks Improve patient care Cut costs of treatment Therefore, the term Medical Informatics itself has undergone a transformation The generally accepted terminology now is Health(care) Informatics This includes (Bio)Medical-, Clinical-, Health-, Patient-, Nursing-, Public Health Informatics
49 Gunther Eysenbach s diagram 1999
51 References A History of Medical Informatics in the United States: (Collen, AMIA Press 1996) Information Retrieval: A Health Care Perspective (Hersch, Springer-Verlag, 1996) Medical Informatics : Computer Applications in Health Care (Shortliffe, Addison Wesley, 1990). Collen MF. Origins of Medical Informatics. West J Med Dec; 145:
52 References Eysenbach G, Ryoung Sa E, Diepgen TL. Shopping around the Internet today and tomorrow: towards the millennium of cybermedicine. BMJ 1999;319:1294 Lindberg DA. The National Library of Medicine and Medical Informatics. West J Med 1986 Dec;145: Altman RB. Informatics in the Care of Patients: Ten Notable Challenges. West J Med 1997 Feb.
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