Scientific Integrity. Text and Cases i n Responsible Conduct of Research. Francis L. Macrina
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1 Scientific Integrity Text and Cases i n Responsible Conduct of Research Francis L. Macrina
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3 Contributors xi Foreword xii i Preface xvii Acknowledgments xix A Website Companion-for Scientific Integrity: Text and Cases in Responsible Conduct of Research, Third Edition xx Note to Students and Instructors xxi chapter 1 Methods, Manners, and the Responsible Conduct o f Research Francis L. Macrina 1 Overview Scientific Misconduct Responsible Conduct of Research Conclusion Discussion Questions References Resource s chapter 2 Ethics and the Scientist Bruce A. Fuchs and Francis L. Macrina 1 9 Overview Ethics and The Scientist Underlying Philosophical Issues Utilitarianism Deontology Critical Thinking and the Case Study Approach Moral Reasoning in the Conduct of Science Conclusio n Discussion Questions Case Studies References Resource s chapter 3 Mentoring Francis L. Macrina 39 Overview Characteristics of the Mentor Trainee Relationship Selection of a Mentor Mentoring Guidelines Conclusion Discussion Questions Cas e Studies References Resources chapter 4 Authorship and Peer Review Francis L. Macrina 6 1 Scientific Publication and Authorship The Pressure to Publish The Need for Authorship Criteria Instructions to Authors Guidelines for Authorship Peer Review The Workings of Peer Review Being a Peer Reviewer Emerging Trends and Policies Conclusion Discussion Questions Cas e Studies Resources
4 chapter 5 chapter 6 Use of Humans in Biomedical Experimentatio n Paul S. Swerdlow 9 1 Overview Are You Conducting Human Subject Research? The Issue of Informed Consent Institutional Review Boards The Institutional Revie w Board and the Informed Consent Issue The Institutional Review Board an d Expedited Review Human Experimentation Involving Special Populations The Health Insurance Portability and Accountability Act (HIPAA) Feta l Tissue and Embryonic Stem Cell Research Conclusion Discussion Question s Case Studies The Declaration of Helsinki References Resources Use of Animals in Biomedical Experimentation Bruce A. Fuchs and Francis L. Macrina 127 Introduction Ethical Challenges to the Use ofanimals in Research Practical Matters: Constraints on the Behavior ofscientists Political Realities: Then and Now Discussion Questions Case Studies References Resource s chapter 7 Managing Competing Interests S. Gaylen Bradley 159 Introduction Conflict ofeffort Conflict ofconscience Conflict ofinterest Managing Competing Interests Conclusion Discussion Questions Cas e Studies Resources chapter 8 Collaborative Research Francis L. Macrina 187 Overview The Nature ofcollaboration A Syllabus of Collaboration Principles Collaboration Models Conclusion Discussion Questions Case Studies References Resources chapter 9 chapter 10 Ownership of Data and Intellectual Propert y Thomas D. Mays 21 1 Introduction Review ofownership ofresearch Data Rights in Tangible Personal Property Trade Secrets Trademarks Copyright s Patents Patent Law in the Age ofbiotechnology Seeking a Patent Conclusion Discussion Questions Case Studies Author 's Note Resources Glossary Genetic Technology and Scientific Integrit y Cindy L. Munro 247 Introduction Genetic Screening and Diagnosis The Human Genome Projec t Manipulating Genes Conclusion Discussion Questions Case Studie s References Resources
5 chapter 1 1 Scientific Record Keeping Francis L. Macrina 269 Introduction Why Do We Keep Records? Defining Data Data Ownership Data Storage and Retention Tools of the Trade Laboratory Record-Keeping Policies Suggestions for Record Keeping Electronic Record Keepin g Conclusion Discussion Questions Case Studies References Resource s appendix I Surveys as a Tool for Training in Scientific Integrit y Michael W. Kalichman 297. appendix II Student Exercises 32 1 appendix III Standards of Conduct 333 appendix IV Sample Protocols for Human and Anima l Experimentation 34 3 app en d i x V Example of a US. Patent Specification 373 app en di x VI Laboratory Notebook Instructions 387 Index 393
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