Tested Interventions/Early Diagnosis Interventions/Treatment (Full List)

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1 Tested Interventions/Early Diagnosis Interventions/Treatment (Full List) Allmark P. & Tod AM., (2009). The evaluation of public health education initiatives on smoking and lung cancer: an ethical critique In: Peckham S. Hann A. (eds) Public Health Ethics and Practice. Policy Press. London Chapter 5. p Allmark P., Tod AM., Abbott J. (2007). Philosophy and health education: the case of lung cancer and smoking. In: Philosophical Enquiry into Education John Drummond and Paul Standish (Eds) Palgrave Macmillan. London. Hurt N. C., Roberts K., Rogers T.K., Griffiths G.O., Hood K., Prout H., Nelson A., Fitzgibbon J., Barham A., Thomas-Jones E., Edwards Tudor R., Yeo Tien S., Hamilton W., Tod A., Neal R.D. (2013). A feasibility study examining the effect on lung cancer diagnosis of offering a chest X-ray to higher-risk patients with chest symptoms: protocol for a randomized controlled trial Trials. 14:405. DOI: / / Athey V.L.R., Suckling R., Tod A.M., Walters S.J., Rogers T.K. (2011). Early diagnosis of lung cancer: evaluation of a community-based social marketing intervention. Thorax 67: doi: /thoraxjnl Tod A.M. & Rose J. (2010). Overcoming delay in the diagnosis of lung cancer: a qualitative study. Nursing Standard. 24, (31) Tod A.M., Allmark P., Craven J. (2008). Diagnostic delay in lung cancer: a qualitative study. Journal of Advanced Nursing. 61(3), Clary Macy C. (2004). Article about lung cancer did not discuss nonsmokers with the disease. Oncol Nurs Forum. JanFeb;31(1):13; author reply 13. Brevetti G.R., Sasse K.C., Khan J.H., Wilson M.W., ClaryMacy C., Brevetti L.S., Hall T.S., Jablons D. (2000). Giant tumors of the chest: preoperative embolization and resection J Cardiovasc Surg (Torino). Dec;41(6): Schneider D.B., ClaryMacy C., Challa S., Sasse K.C., Merrick S.H., Hawkins R., Caputo G., Jablons D.J. (2000). Positron emission tomography with f18fluorodeoxyglucose in the staging and preoperative evaluation of malignant pleural mesothelioma. Thorac Cardiovasc Surg Jul;120(1): Brevetti G.R., ClaryMacy C., Jablons D.M. (1999). Pulmonary placental transmogrification: diagnosis and treatment. J Thorac Cardiovasc Surg. Nov;118(5):9667. Khan J.H., Rahman S.B., ClaryMacy C., Kerlan R.K., George T.I., Hall T.S., Jablons D.M.(1998). Giant solitary fibrous tumor of the pleura. Ann Thorac Surg May;65(5): Jablons D.M., Cheng S.J., ClaryMacy C., Hirsch FR. (2002). 1st International Lung Cancer Conference in Beijing, October 2730,2002. Lung Cancer Aug;41(2): Robinson B.M., Kennedy C., McLean J., McCaughan B.C. (2011). Node-negative non-small cell lung cancer: pathological staging and survival in 1765 consecutive cases. Journal of Thoracic Oncology, 08/2011; 6(10): Test Interventions (Full List) Page 1

2 Robinson B.M., Kennedy C., McLean J., McCaughan B.C. (2011). Survival and Pathological Staging in Node-Negative Non-Small Cell Lung Cancer Heart Lung & Circulation 12/2011; 20(12):783. Yan T.D, Cao C.Q, Boyer M., Tin M.M., Kennedy C., McLean J., Bannon P.G., McCaughan B.C. (2011). Improving survival results after surgical management of malignant pleural mesothelioma: an Australian institution experience. Annals of thoracic and cardiovascular surgery, 06/2011; 17(3): Yan T.D, Tin M., Boyer M., McLean J, Bannon P.G., McCaughan B.C (2009). Treatment failure after extrapleural pneumonectomy for malignant pleural mesothelioma. Journal of Thoracic Disease. 12/2009; 1(1):23-8. Yan T.D., Boyer M., Tin M.M., Wong D., Kennedy C., McLean J, Bannon P.G, McCaughan B.C (2009). Extrapleural pneumonectomy for malignant pleural mesothelioma: outcomes of treatment and prognostic factors. The Journal of thoracic and cardiovascular surgery, 10/2009; 138(3): Yan T.D, Boyer M., Tin M.M., Sim J., Kennedy C., McLean J., Bannon P.G., McCaughan B.C (2009). Prognostic features of long-term survivors after surgical management of malignant pleural mesothelioma. The Annals of thoracic surgery 06/2009; 87(5): Viney R.C, Boyer M.J, King M.T, Kenny P.M., Pollicino C.A, McLean J.M., McCaughan B.C., Fulham M.J. (2004). Randomized controlled trial of the role of positron emission tomography in the management of stage I and II non-small-cell lung cancer. Journal of Clinical Oncology 07/2004; 22(12): McLean J. & McCaughan B.C. (2013). Diagnosis and treatment: the journey of a patient with malignant pleural mesothelioma. Sydney: The Baird Institute. van Zandwijk N., Clarke C., Henderson D., Musk A.W., Fong K., Nowak A., Loeragan R., McCaughan B., Boyer M., Feigen M., Currow D., Schofeild P., Ivimey B., Pavlakis N., McLean J., Marshall H., Leong S., Keena V., Penman A. (2013). Guidelines for the diagnosis and treatment of malignant pleural mesothelioma Journal of Thoracic Disease, Vol. 5, No 6, (December). Morgan D.D. & White K.M. (2012). Occupational therapy interventions for breathlessness at the end of life. Current Opinion in Supportive and Palliative Care, 6(2), White K.M. (2013). Occupational therapy interventions for people living with advanced lung cancer. Lung Cancer Management, 2(2), Field J., Darlison L., Horne H., Hatton M., Lim E., McKinley D. (2013). 11th Annual British Thoracic Oncology Group Conference. Lung Cancer Management Volume 2, Issue 2, , Treasure T., Lang-Lazdunski L., Waller D., Bliss J., Tan C., Entwisle J., Snee M., O'Brien M., Thomas G., Thomas G., Senan S., O'Byrne K., Kilburn L., Spicer J., Landau D., Edwards J., Coombes G., Darlison L., Peto J. (2011). Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study The Lancet Oncology Volume 12, Issue 8, August 2011, Moore S., Darlison L., Tod A.M., (2010). Living with mesothelioma. A literature review European Journal of Cancer Care Volume 19 Issue 4, Test Interventions (Full List) Page 2

3 Darlison L. (2008). Improving Mesothelioma Services Lung Cancer in Practice Vol 5 No 3. Darlison L. (2008). Mesothelioma Chapter. Oxford Handbook of Respiratory Nursing, edited by Terry Robinson and Jane Scullion. Oxford University Press. Darlison L. (2008). Advances in Lung Cancer Care Cancer Nursing Practice July 2008, Volume 7, Issue 6. Darlison L. (2008). The After Effects of Exposure Cancer Nursing Practice June 2008, Volume 7, Issue 5. Taub R.N., Keohan M.L., Chabot J., Fountain K., Plitsas M. (2000). Peritoneal Mesothelioma. Current Treatment Options. Oncology. 4: Talbot S.M., Keohan M.L., Hesdorffer M., Orrico R., Bagiella E., Troxel A.B., Taub R.N. (2005). A Phase II trial of Temozolomide in Patients with Unresectable or Metastatic Soft Tissue Sarcoma.Cancer. Cancer 98: Ayyoub M, Taub RN, Keohan M, Hesdorffer M, Metthez G, Memeo L, Mansukhani M, Hibshoosh H,. Hesdorffer CS, Valmori D. The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma. Cancer Immunity, 2004 Aug 9; 4:7. Borczuk AC, Taub RN, Hesdorffer M, Hibshoosh H, Chabot JA, Keohan ML, Alsberry R, Alexis D, Powell CA. P16 loss and mitotic activity predict poor survival in patients with peritoneal malignant mesothelioma. Clin. Cancer Res, ,3303:8. Hesdorffer, ME, Taub RN Malignant Pleural Mesothelioma J R College Physicians Edinburgh 2007 Aug 37(3), 232 Hesdorffer, M, Taub, R: Continuing Medical Education Module in Respiratory Medicine on Mesothelioma. Royal College of Edinburgh On line CME publication, March 2007 Hesdorffer, M, Chabot J, Keohan M, Fountain, K, Talbot, S, Gabay, Taub R. Combined Resection, Chemotherapy and Whole Abdominal Radiation for the Treatment of Peritoneal Mesothelioma Malignant. Am Journ Clin Onc, 2008 Feb 31(1):49:54 Hesdorffer,M Chabot J, DeRosa, C, Taub, R. Peritoneal Mesothelioma Current Treatment Options. Oncology, 2008 Jun ;9(2-3);180:90. Boyar MS, Hesdorffer M, Keohan ML, Jin Z, Taub RN. Phase II Study of Temozolomide and Thalidomide in Patients with Unresectable or Metastatic Leiomyosarcoma Sarcoma. 2008;2008: Kluger MD, Taub RN, Hesdorffer M, Jin Z, Chabot JA. Two-stage operative cytoreduction and intraperitoneal chemotherapy for diffuse malignant peritoneal mesothelioma: Operative morbidity and mortality in phase I and II trials. Eur Journ Surg Onc 2010 Oct 36(10);997:1003. Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M. Germline. BAP1 mutations predispose to malignant mesothelioma. Nat Genet Aug 28,43(10);1022:5. Test Interventions (Full List) Page 3

4 Wagmiller J, Keohan,M, Chabot J, Fountain K, Hesdorffer M, Taub R. Peritoneal Mesothelioma: The Columbia Experience in Malignant Mesothelioma. Editors: Pass H, Vogelzang N, Carbone M Springer Publishing, 2005 Klamerus,J, Brahmer, J, Ettinger, D, Hesdorffer, M Johns Hopkins Medicine Patient's Guide to Lung Cancer. Editors Shockney, L, Shapiro, G Jones and Bartlett Learning 2010 Pass, H, Hesdorffer, M, Lake, S 100 Questions and Answers about Mesothelioma in process. Jones & Bartlett Learning; 5th edition manuscript submitted for publication 2012 Vonderheide RH, Schultze JL, Anderson KS, Maeker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt- Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KX, Hahn WC, Nadler LM. Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals. Cancer Res Dec 61(23); Edelman MJ, Smith R, Hausner P, Doyle LA, Kendall J, Bedor M, Bisaccia S. Phase II trial of the novel retinoid, bexarotene, and gemcitabine plus carboplatin in advanced non-small-cell lung cancer. J Clin Oncol Aug 23(25); 5774:8. Erratum in: J Clin Oncol Nov; 23(31): Edelman MJ, Watson DM, Wang X, Kratzke RA, Mauer AM, Green MR, Vokes EE, Graziano SL, Masters GA, Bedor MM. Eicosanoid modulation in advanced non-small cell lung cancer expression is a positive predictive factor for celecoxib + chemotherapy-cancer and Leukemia Group B Trial J.Clin Oncol Feb 26(6);848:55 Bridges BB, Thomas L, Hausner PF, Doyle LA, Bedor M, Smith R, BRahmer J, Edelman MJ. Phase II trial of gemcitabine/carboplatin followed by paclitaxel in patients with performance status = 2,3 or other significant co-morbidity (HIV infection or s/p organ transplantation) in advanced non-small cell lung cancer. Lung Cancer Jul 61(1);61:6. Y-S Lee, J-W Lee, J-W Jang, X-Z Chi, J-H Kim, Y-H Li, M-K Kim, D-M Kim, B-S Choi, E-G Kim, J-H Chung, O-J Lee, Y-M Lee, J-W Suh, L-S Chuang, Y Ito, and S-C Bae. Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma Cancer Cell, 2013 Nov 24; 1:14 Lee K-S, Lee Y-S, Lee J-M, Ito K, Cinghu S, Kim J-H, Jang J-W, Li Y-H, Goh Y-M, Chi X-Z, Wee H, Lee H-W, Hosoya A, Chung J-H, Jang J-J, Kundu J K, Surh Y-J, Kim W-J, Ito Y, Jung H-S, Bae S-C. Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer. Oncogene Jun 10 29(23);3349:61. Grimmett C, Armes J, Breckons M, Calman L, Corner J, Fenlon D, Hulme C, May C M, May C R, Ream E, Richardson A, Smith P, Yardley l, Foster C. RESTORE: an exploratory trial of an online intervention to enhance self-efficacy to manage problems associated with cancer-related fatigue following primary cancer treatment: study protocol for a randomized controlled trial. Trials 14 (1);1745. Uyterlinde W, Chen C, Nijkamp J, Obbink MG, Sonke JJ, Belderbos J, van den Heuvel M. Treatment adherence in concurrent chemoradiation in patients with locally advanced non-small cell lung carcinoma: Results of daily intravenous prehydration. Radiother Oncol Mar 110(3);488:92. van den Heuvel MM, Uyterlinde W, Vincent AD, de Jong J, Aerts J, Koppe F, Knegjens J, Codrington H, Kunst PW, Dieleman E, Verheij M, Belderbos J. Additional weekly Cetuximab to concurrent Test Interventions (Full List) Page 4

5 chemoradiotherapy in locally advanced non-small cell lung carcinoma: Efficacy and safety outcomes of a randomized, multi-center phase II study investigating. Radiother Oncol Jan 110(1);126:31 Chen C, Uyterlinde W, Sonke JJ, de Bois J, van den Heuvel M, Belderbos J. Severe late esophagus toxicity in NSCLC patients treated with IMRT and concurrent chemotherapy. Radiother Oncol Aug 108(2);337:41. Uyterlinde W, Belderbos J, Baas C, van Werkhoven E, Knegjens J, Baas P, Smit A, Rikers C, van den Heuvel M. Prediction of acute toxicity grade 3 in patients with locally advanced non-small-cell lung cancer receiving intensity modulated radiotherapy and concurrent low-dose Cisplatin. Clin Lung Cancer Sep14(5);541:48. Uyterlinde W, Chen C, Kwint M, de Bois J, Vincent A, Sonke JJ, Belderbos J, van den Heuvel M. Prognostic parameters for acute esophagus toxicity in intensity modulated radiotherapy and concurrent chemotherapy for locally advanced non-small cell lung cancer. Radiother Oncol Jun 107(3);392:97. Nijkamp J, Rossi M, Lebesque J, Belderbos J, van den Heuvel M, Kwint M, Uyterlinde W, Vogel W, Sonke JJ. Relating acute esophagitis to radiotherapy dose using FDG-PET in concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer. Radiother Oncol Jan106(1);118:23. Kwint M, Uyterlinde W, Nijkamp J, Chen C, de Bois J, Sonke JJ, van den Heuvel M, Knegjens J, van Herk M, Belderbos J. Acute esophagus toxicity in lung cancer patients after intensity modulated radiation therapy and concurrent chemotherapy. Int J Radiat Oncol Biol Phys Oct 1 84(2);e223:8. Giacone G, Baas P, Uyterlinde W. Systemic Treatment of Non-small cell lung cancer; chapter on symptom management. Oxford Oncology Library. 128 pages May Test Interventions (Full List) Page 5

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