International Consortium for Harmonization of Clinical Laboratory Results. Operating Procedures

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "International Consortium for Harmonization of Clinical Laboratory Results. Operating Procedures"

Transcription

1 International Consortium for Harmonization of Clinical Laboratory Results Operating Procedures Approved: February 11, 2014

2 Background Results from clinical laboratory measurement procedures should be comparable irrespective of the laboratory, method or time when measurements are made. Comparable results are necessary to allow meaningful interpretation of a patient s condition over time, to allow clinical practice guidelines to be implemented, to allow data from clinical research to be used to develop guidelines, and for results to be aggregated into electronic health records. A lack of recognition that results are neither standardized nor harmonized may lead to erroneous clinical, financial, regulatory, or technical decisions. To address these problems, an international conference recommended that an international infrastructure be developed to provide: a systematic approach for prioritization of measurands to be harmonized based on medical importance and the technical feasibility to achieve harmonization; an information portal on global harmonization activities to avoid duplication of effort; and procedures to implement harmonization for measurands for which no reference measurement procedure was likely to be developed. (Roadmap for harmonization of clinical laboratory measurement procedures. Clinical Chemistry 2011;57: ) Mission Provide a centralized process to organize global efforts to achieve harmonization of clinical laboratory test results. Scope Provide a global infrastructure to prioritize, organize and manage harmonization of clinical laboratory results which will optimize public health activities and patient care. These activities will eliminate duplication of effort and maximize resource utilization. The infrastructure includes: A systematic process that will allow the prioritization and organization of work, on a global scale, for those measurands that are the most medically important and technically feasible for harmonization. Processes for harmonization of a measurand when no reference measurement procedure is available. Work products for harmonization that will be listed by the Joint Committee on Traceability in Laboratory Medicine (JCTLM) permitting IVD manufacturers to meet various traceability requirements for regulatory purposes. A website that will serve as a resource for information on global activities to harmonize or standardize clinical laboratory measurement procedures. 2 P age

3 Value proposition Clinical practice guidelines frequently base diagnostic and therapeutic decisions on laboratory test results. Such clinical decisions will be compromised, leading to erroneous clinical, financial, regulatory, or technical decisions, if the test results are not consistent among different measurement procedures, laboratories and times of measurement. Although several organizations are addressing harmonization of test results, there is no global organizational oversight to inform decisions on prioritization and to ensure resources and technical solutions are optimally applied. This international consortium will provide oversight for prioritization of the medical importance of measurands for harmonization, information on the technical feasibility to achieve harmonization, coordination of harmonization activities, and management of specific technical processes to achieve harmonization of a measurand. Implementation of the infrastructure for a harmonization process will require the involvement and cooperation of international clinical laboratory and medical organizations, IVD manufacturers, metrology institutes, standard-setting organizations, public health organizations and regulatory agencies. Structure and Operational Overview International Consortium for Harmonization of Clinical Laboratory Results Strategic Partners Group Council Harmonization Oversight Group Harmonization Implementation Groups Special Working Groups Secretariat/Host - AACC The International Consortium for Harmonization of Clinical Laboratory Results (ICHCLR) will be a hosted by the AACC which will serve as the Secretariat. As the Secretariat/host organization, the AACC will manage all administrative, finance, accounting, and marketing services for a fee. The AACC will also 3 P age

4 provide liability protection and tax exempt status, and will serve as the title-holding entity in all matters regarding the ICHCLR (intellectual property rights copyrights, trademarks, patents, etc.). The Consortium will be governed by a Council whose members represent organizations that contribute at an annual financial level defined by the Council to support the core administrative functions of the program. The Council will be responsible for the fiduciary and administrative oversight of the consortium. The Council will be responsible for determining the scope of operations of the ICHCLR within a budget approved by the AACC. Stakeholders who are committed to harmonization of clinical laboratory results (e.g. clinical laboratory and medical organizations, IVD manufacturers, metrology institutes, standard-setting organizations, public health organizations, regulatory agencies and individuals) may become members of the Strategic Partners Group (SPG). The SPG supports the program by submitting measurands in need of harmonization, nominating experts for consideration to serve on the Harmonization Oversight Group (HOG), and reviewing and commenting on harmonization project plans and milestone updates from Harmonization Implementation Groups (HIGs). Council members are also members of the Strategic Partners Group. The Harmonization Oversight Group (HOG) is the body responsible for organization and coordination of the harmonization process. The HOG will proactively communicate with stakeholders to provide updates on harmonization activities and to solicit input from them on relevant activities in their organizations. The HOG will establish and maintain a web site to coordinate information about harmonization activities. The HOG will review measurand submissions. In most cases, a Special Working Group (SWG) of experts in a particular measurand will be appointed to review the data and make a recommendation to the HOG. The HOG will assign a medical importance classification, and provide information on the technical feasibility to achieve harmonization for a measurand. The HOG will cooperate with other organizations to coordinate harmonization work. When a reference measurement procedure can be developed, the HOG will preferentially refer the harmonization activity to an organization with expertise in such work. For harmonization of a particular measurand to be managed by the HOG, a Harmonization Implementation Group (HIG) will be formed, funding obtained and the HIG given responsibility to organize and conduct the harmonization activity. Funding Members of the Council will fund the adminsitrative costs of the program with an annual contribution of $50,000 (subject to annual review) per member per year. Members of the Strategic Partners Group will be assessed a fee of $500 (subject to annual review) per year. Financial support for harmonization of a specific measurand, under the direction of a HIG, will be obtained from interested stakeholders by the HOG in advance of initiating a specific project. 4 P age

5 The work products, e.g. reference materials, of HIGs may generate revenue as the program progresses. Such revenue will go to a general fund to offset operating expenses or to be reinvested in other harmonization projects. Detailed Operational Procedures for the Harmonization Oversight Group Table of Contents 1. Definitions 2. Abbreviations 3. Harmonization Oversight Group 4. Special Working Group 5. Harmonization Implementation Group 6. Funding for harmonization of a specific measurand 7. Acceptance of new harmonization materials and/or procedures for a measurand 8. Revision of Operational Procedures for the Harmonization Oversight Group 9. Policies 10. Forms 5 P age

6 1. Definitions A. Essential terms: Harmonization A process that achieves uniform results among measurement procedures when no reference measurement procedure exists. Standardization - A process that achieves uniform results among measurement procedures based on calibration traceability to Système International d'unités (SI; International System of Units) using a reference measurement procedure. NOTE: the term harmonization is used in this document to refer to either harmonization or standardization as applicable. B. Other terms: Higher-order reference measurement procedure a measurement procedure that is highly specific for a measurand, thoroughly validated, and whose calibration is directly traceable to SI using a primary reference material or the measurement procedure itself defines the SI. Industry - an organization that manufactures and/or distributes materials used in clinical laboratory testing. For example, industry includes manufacturers or distributors of instruments, reagents, cell lines, calibrators, controls, reference materials, proficiency testing or external quality assessment programs. Note that reference materials may also be provided by metrology organizations and proficiency testing or external quality assessment programs may also be provided by public health or professional organizations. Measurand the quantity intended to be measured. Specification of a measurand includes the specific molecular form or species that is measured as well as the matrix in which that molecule is contained. Note the term analyte (component represented in the name of a measurable quantity) is sometimes used when measurand is intended. Primary reference material a pure substance with a certificate of analysis that describes its purity and the molecular form of the substance. Secondary reference material a material, frequently in the matrix of the clinical samples intended to be measured, which has its value assigned by measurement or by a consensus process. Stakeholder - any individual or entity with an interest in harmonization of clinical laboratory results including: clinical practice groups, laboratory practice groups, in-vitro diagnostics manufacturers, public health organizations, metrology institutes, standards development organizations, regulatory organizations, proficiency testing or external quality assessment providers. 6 P age

7 2. Abbreviations GMT Greenwich Mean Time HOG Harmonization Oversight Group HIG Harmonization Implementation Group ISO International Organization for Standardization IVD In-Vitro Diagnostics JCTLM Joint Committee for Traceability in Laboratory Medicine NIST National Institute for Standards and Technology (USA) PT/EQA Proficiency Testing/ External Quality Assessment RMP Reference Measurement Procedure SI Système International d'unités (International System of Units) SWG - Special Working Group 3. Harmonization Oversight Group (HOG) The HOG is the body responsible for organization and coordination of the harmonization process. The HOG provides oversight for prioritization of measurands for harmonization, for organizing and disseminating information on global activities for harmonization of clinical laboratory measurement procedures, and for either referring work to another organization or managing a harmonization effort for a specific measurand. Figure 1 shows an organizational diagram for HOG operation. 7 P age

8 3.2 Stakeholders (Strategic Partners Group): Clinical practice groups Metrology Institutes Laboratory practice groups Standards organizations IVD manufacturers Regulatory organizations Public health organizations PT/EQA organizations / Coordination / Cooperation If work is underway, refer to that group If RMP is possible, refer to another group 3 Harmonization Oversight Group Communication Operation 3.3 Evaluate measurand proposals When no RMP / 6 Solicit champion and funding Clinically affected entity Economically affected entity / / 4 Special Working Group Review priority and technical feasibility Recommendation to Harmonization Oversight Group / 5 Harmonization Implementation Group Technical plan Surveillance plan Implement the plans Achieve JCTLM listing Figure 1. Organizational diagram for HOG operation. Numbers refer to sections in this document. Adapted from: Roadmap for harmonization of clinical laboratory measurement procedures; Clinical Chemistry 2011; 57: P age

9 The responsibilities of the HOG include: Communicating with the SPG for submission of measurands for consideration and reporting the status of harmonization for measurands. Decisions on the classification of medical importance for harmonizing a measurand based on input from a SWG. Decisions on the technical feasibility of harmonization based on input from a SWG. Creation and oversight of SWGs. Obtaining and providing information on the status of harmonization for measurands already being addressed, either within ICHCLR or by a cooperating organization. Cooperating with other organizations with expertise and interest to develop a reference measurement procedure or a strong interest in a particular measurand, and providing information on the status and a link to the organization addressing such a measurand. Creating a HIG and soliciting funding to develop and execute a harmonization plan for a high priority measurand for which no other organization is able to accept the task. Review progress of HIGs on a regular basis and provide feedback. Review and approve work products of HIGs prior to final implementation. Submission of approved work products of HIGs to the Joint Committee for Traceability in Laboratory Medicine (JCTLM) for review and listing. Communication of harmonization issues and technical advances to regulatory bodies. Dissemination of information on the status of harmonization activities being conducted by this or other organizations to avoid duplication of effort. Develop and coordinate collaborations and development of resources needed to support and promote harmonization in laboratory medicine. The HOG should meet at least annually (it is anticipated that an annual meeting will be face to face for at least the first 3 years). Virtual meetings will be preferred for most business, to minimize costs and to facilitate global participation. The HOG will issue an annual report, posted on the web site, describing the scientific and business status of its harmonization activities. The Council has the responsibility for oversight of the HOG. 3.1 HOG membership The HOG typically has 8 members. New members of the HOG will be selected by the Council from individuals nominated by the SPG. The Council is responsible to ensure that the HOG membership represents a broad range of existing and emerging technologies and disciplines. Appointments will be for 3 years on a calendar year starting January 1 (GMT -5) and ending December 31 (GMT-5). An individual may be reappointed for 1 additional 3 year term. The composition will include 2 members from industry (nominated by an industry or by an industry related SPG), 2 from non-industry organizations (nominated by an organization SPG) and 4 ad-hoc members based on expertise (nominated by any SPG). Four of the inaugural HOG members will serve initial 2 year terms to introduce stagger. The initial HOG terms will end December 31, 2015 (two year terms) or December 31, 2016 (three year terms). Nominators must provide a CV of the nominee and describe the expertise and experience of the individual with regard to harmonization development activities. Selection of HOG members should consider the 9 P age

10 desirability of having a mix of senior and junior scientists who have demonstrated expertise in individual harmonization projects to ensure the sustainability of the harmonization program. A HOG member s duty will be to the HOG and not to be a representative of the particular SPG that made the nomination. HOG members will not represent a specific industry or organization but will ensure that the general perspective of industry and organizations is represented. All HOG members shall disclose (see Section 3.2) financial or other interests that may be perceived to have the potential to impact their ability to offer an unbiased view of matters that may come before the HOG. The HOG chair will be selected by the Council and must have a minimum of one year service as a HOG member to be eligible for chair. A vice-chair will also be selected by the Council and this person must be on a different term rotation schedule than the chair. The vice-chair will serve in a deputy role, but will not automatically be in line to become the next chair. Qualifications to be a HOG member: Breadth of experience in harmonization activity Experience in consensus committee work Commitment to the time necessary to fulfill the role (approximately 2 days per month plus an annual face-to-face meeting) 3.2 Communication with the Strategic Partners Group (stakeholders). The HOG will communicate with the SPG to provide updates on harmonization and to solicit input on relevant activities in their organizations. The HOG will establish and maintain a web site to coordinate information about harmonization activities. The web site will provide information on: the status of harmonization of measurands; organizations working to harmonize measurands; literature resources related to harmonization of measurement procedures; recommendations related to implementing harmonization of measurands, documenting such harmonization, and informing end users of the calibration traceability of measurement procedures for a particular measurand; and other information of interest to stakeholders as may be determined by the HOG. The web site will also provide an on-line process for submission of candidate measurands to be prioritized for harmonization. 3.3 Evaluation of measurands submitted for harmonization The HOG will review measurand submissions and determine if harmonization is likely to be medically important and technically feasible. The HOG will assign a medical importance classification and it will recommend that a medically important measurand be harmonized if it is technically feasible to do so. If it is not technically feasible to achieve harmonization, the medical importance will be unchanged and the measurand will be reviewed periodically for any change in feasibility Appoint a Special Working Group (SWG; see Section 4) If needed, the HOG will appoint a SWG to review available information (provided by the submitter of a measurand for consideration, obtained from available literature, or by solicitation from experts in the field) on a given measurand. The SWG will make a recommendation on the medical importance of harmonization, the technical feasibility for harmonization, and the gap between what is known about calibration for a measurand and what is determined to be needed to proceed with harmonization. 10 P age

11 3.3.3 Establish medical importance and technical feasibility for harmonization The HOG will establish the medical importance for harmonization of a measurand. Medical importance should have categories (e.g. high, medium, low) rather than a numerical ranking. The technical feasibility to achieve harmonization will be evaluated separately from medical importance. The categories will enable medically important analytes to be addressed based on the technical feasibility of achieving harmonization and the ability to raise funds. A list of measurands indicating medical importance will be maintained on the harmonization.net web site along with a summary of justifications for the medical importance and technical feasibility. The list will be reviewed periodically to determine if a change in classification for measurands is appropriate Appeal of a medical importance or technical feasibility decision An appeal for reconsideration may be made in writing to the HOG within 60 days of posting a medical importance or technical feasibility decision. The HOG and the SWG will review the evidence and respond to the appeal within 60 days Referral to other groups for harmonization of a given measurand In the event a submitted measurand is already being addressed by another organization, or an organization has expressed interest in harmonizing a specific measurand, the HOG will typically refer the work to that group unless the HOG determines there is a technical limitation in the approach being developed or used. The HOG will maintain communication with that group in order to report the status of the project via the harmonization.net website. 3.4 Establishing a harmonization activity for a measurand Measurands suitable for development of a reference measurement procedure (standardization) When the SWG determines that a reference measurement procedure is feasible and should be developed, the HOG will preferentially refer the standardization work to a group with experience in standardization and which expresses interest in the project. The HOG will maintain communication with that group in order to report the status of the project via the harmonization.net website. In the event no other group is available to standardize the measurand, the HOG may seek funding and create a HIG to standardize the measurand Measurands for which no reference measurement procedure is likely to be developed For a measurand that will have a harmonization program developed, the HOG will appoint a HIG (see Section 5) with initial responsibility for developing a harmonization project proposal. 11 P age

12 Based on the project proposal, the HOG and HIG will jointly solicit financial support for the harmonization activity. Once financial support is available, the HIG will be charged to undertake the harmonization activity. 3.5 Checklist maintenance The checklists and report formats used for measurand submission and evaluation are maintained by the HOG who may seek assistance from a SWG in maintaining the checklists. 4. Special Working Group (SWG) When needed, the HOG will create an ad-hoc Special Working Group to review available information and to determine if any other group is addressing that measurand. The SWG will provide a report to the HOG that addresses: the medical importance for harmonization, the technical feasibility for harmonization, and the gap between what is known about calibration for a measurand and what is determined to be needed to proceed with harmonization. The SWG will be dissolved upon submission of a report to the HOG. A SWG will typically include 4-6 members with expertise in the clinical use and laboratory measurement of the measurand. The HOG will appoint members based on nominations included with the submission of a measurand and on solicitation of candidates from colleagues. Potential members will be asked to commit the time necessary for the work (approximately 1 day per week for 3 months). The HOG will appoint one member to be chair of the SWG. Deliberations regarding the members for a SWG will be confidential. 4.1 Special Working Group (SWG) Operation The submitter of a request to harmonize a measurand will provide information using a structured submission checklist. The SWG will use this list as well as additional published or proprietary information, and expert opinion, to assist in the assessment. The SWG will not conduct original investigations to obtain missing information but may make a recommendation to the HOG that such information is needed to make a final determination of medical importance or technical feasibility for harmonization. The goal for the SWG is to assemble and evaluate information related to the need for and feasibility of harmonization, and report to the HOG in 3 months. The SWG will conduct meetings by electronic means Evaluation of medical importance for harmonization Medical importance will be based primarily on the impact on patient care of a lack of harmonized test results. Structured checklists will be used to evaluate the available information and to identify missing information Evaluation of technical feasibility of achieving harmonization Feasibility to achieve harmonization will be evaluated separately from medical importance. Feasibility will be evaluated based on available technical information using a structured checklist. 12 P age

13 4.1.3 Report of recommendations The SWG will issue a report of its findings using a structured format. The report will also include identification of missing information that is needed, or would be useful, to assess medical importance or technical feasibility, and suggestions for membership in a HIG that may be formed for that measurand. The SWG report and the final classification of medical importance and assessment of technical feasibility by the HOG with explanation will be posted to the harmonization.net web site. 5. Harmonization Implementation Group (HIG) For a measurand that is selected to have a harmonization program developed, the HOG will create a Harmonization Implementation Group with responsibility for developing and executing the program. The HOG will appoint members based on nominations included with the submission of a measurand, recommendations from the SWG for that measurand, and/or other experts in the clinical use and laboratory measurement of the measurand. In addition, potential members will be asked to confirm that they are able to commit the necessary time for the work. The HOG will appoint one member to be chair of the HIG. Deliberations regarding the members for a HIG will be kept confidential. 5.1 A Harmonization Implementation Group A HIG will consist of up to 10 members with an appropriate mix of expertise to accomplish harmonization for a measurand. The membership must include at least 1 industry professional, 1 clinical practitioner, 1 clinical laboratory professional and 1 member with expertise in implementing harmonization protocols (who may be one of the already named members). A HOG member will serve as a liaison to the HIG. The initial responsibility of the HIG is to develop a draft protocol that includes a technical approach, an estimated timeline and cost to achieve harmonization for a specific measurand. The draft protocol will be used to help solicit funding. The initial work of the HIG will be conducted by electronic communication. Once the harmonization project is initiated, it is anticipated that face-to-face meetings as well as teleconferences will be needed and these expenses will be included in the initial budget estimate. The initial draft protocol should be delivered to the HOG within 3 months. The HIG does not have authority to enter into any financial or contractual arrangements. The Council is responsible to approve any financial arrangements with another group involved in a harmonization activity. Once funding for the harmonization of a measurand is obtained, the HIG will initiate the harmonization activity and manage it to completion. In the event a HIG member resigns, the HIG chair and the HOG will determine who, if anyone, will replace the member Affiliate members of a HIG 13 P age

14 Any interested individual may become an affiliate member of a HIG. Affiliate membership provides a mechanism for interested stakeholders to be informed of progress and to have an opportunity to provide input as the harmonization activity progresses. In general, affiliate members will not be permitted to participate in conference call meetings of a HIG. This restriction on conference call meetings is intended to control cost and to ensure good productivity at the meetings. At the discretion of the HIG chair, one or more guests with special expertise may be invited, as needed, to a particular conference call meeting of the HIG. Transparency will be maintained by providing minutes of meetings to affiliate members and allowing them to submit written comments that will be responded to in writing by the HIG. All minutes, comments and responses will be posted to the harmonization.net web site to ensure transparency and inclusiveness of the process. Open face-to-face meetings of a HIG may be scheduled to enable general review of a harmonization project, to permit dialog with stakeholders regarding resolution of issues or to reach consensus on technical matters. Affiliate members may attend open meetings at their own expense as long as adequate space is available HIG responsibilities The HIG will be responsible for organizing and executing harmonization of measurement procedures for a measurand to include: Assessment of the current status of harmonization Development of a harmonization protocol Development of any needed components such as reference materials, value assignment process, harmonization processes, etc. Organize and implement the harmonization process. It is desirable to include all interested providers of measurement procedures for the measurand in an implementation process. Publication of results. Organization of a submission to obtain JCTLM listing for the harmonization process to include any reference materials or measurement procedures that may be included The submission to JCTLM will be made by the HOG. Creation of a surveillance program for the measurand which will typically be in collaboration with EQA providers. Preparation of an annual report on the status of harmonization for a measurand 5.2 HOG oversight of a HIG for a specific measurand The HOG will ensure that a HIG makes sustained progress on the harmonization activity. The HIG chair will submit a written report to the HOG, at least annually, on the status of a harmonization project and the proposed activity for the next year(s). The report, with any comments from the HOG, will be posted to the harmonization.net web site. In addition, the HOG liaison must be copied into all project related correspondence between HIG members and will also receive an update on progress at regular intervals. 14 P age

15 If the HOG determines that there has been inadequate progress, it may replace the chair or revise the membership of the HIG. In the event a HIG member is removed from the project, the HIG chair and the HOG will determine who, if anyone, will replace the member. In the event the HIG chair is removed, the HOG, with advice from remaining HIG members, will determine who will be appointed as the new chair Termination of a measurand harmonization activity If it is found that there are one or more insurmountable barriers to harmonization of a measurand, the HOG may terminate a project. The priority may remain unchanged and a measurand will be reconsidered for harmonization in the future. The HOG may terminate a project if inadequate progress is being made to achieve harmonization, or if the medical importance changes due to changes in clinical practice. 6. Funding for a HIG for harmonization of a measurand An essential component of this harmonization program is to ensure adequate financial support for a harmonization project. Financial support for harmonization of a specific measurand will be obtained in advance of initiating a project. A potential funder will be able to make an informed decision regarding support based upon the HOG setting out, in advance of solicitation, criteria for priority and feasibility assessment, an experimental approach for harmonization, a timeline and cost estimates, and assurance of transparency of operation. The HOG will solicit support from potentially interested parties including but not limited to: IVD manufacturers, pharmaceutical manufacturers, and other providers of health care products and services that depend on laboratory measurements for a particular measurand to provide quality patient care. 7. Review and approval of materials and/or procedures to accomplish harmonization for a measurand 7.1 Approval process Work products of a HIG will be approved by the HOG. The HIG will prepare documentation that validates their work. Documentation will typically include a peer reviewed publication. 7.2 Submission to JCTLM Once approved by the HOG, a new reference material or procedure for harmonization of a given measurand will be submitted by the HOG to JCTLM for review and listing. 8. Revision of Operational Procedures for the Harmonization Oversight Group 15 P age

16 Revisions to these Operational Procedures may be proposed by the HOG or the Council and accepted if approved by a majority vote of the Council. 9. Policies 9.1 Policy on transparency of proceedings and potential conflicts of interest It is important that the International Consortium for Harmonization of Clinical Laboratory Results is open and transparent with its discussions and decisions on all matters relating to its harmonization activities. Such activities should not be inhibited by undeclared conflicts of interest. Therefore, each participant in a harmonization activity of this organization shall be required to read and sign the conflict of interest policy and disclosure statement. The disclosure statement shall be signed annually by all members of the program s units or sub-units. A conflict of interest does not automatically exclude participation. However, since openness and transparency are important to the harmonization process, it is the duty of each individual to declare the possibility of any potential conflict of interest on each occasion when it may occur. If necessary, the HOG or the Council will determine if a potential conflict is sufficient to preclude any individual from participation. 9.2 Policy on cooperation with other organizations The International Consortium for Harmonization of Clinical Laboratory Results recognizes that global harmonization of results cannot be accomplished by a single organization. Consequently, our policy is to foster cooperative working relationships with all interested stakeholders, and thus avoid duplicative activities and enable optimal use of available resources to achieve the goal of harmonized clinical laboratory results. 9.3 Policy on confidential or proprietary information Confidentiality agreements may be executed if needed to consider confidential or proprietary information relevant to a measurand s evaluation for medical importance or technical feasibility, or to implement a harmonization activity. 16 P age

UNSOLICITED PROPOSALS

UNSOLICITED PROPOSALS UNSOLICITED PROPOSALS GUIDE FOR SUBMISSION AND ASSESSMENT January 2012 CONTENTS 1 PREMIER S STATEMENT 3 2 INTRODUCTION 3 3 GUIDING PRINCIPLES 5 3.1 OPTIMISE OUTCOMES 5 3.2 ASSESSMENT CRITERIA 5 3.3 PROBITY

More information

PROCESS FOR REVIEW AND APPROVAL OF NOMINATED CERTIFIED REFERENCE MATERIALS AND REFERENCE MEASUREMENT METHODS/PROCEDURES JCTLM WG1-P-03

PROCESS FOR REVIEW AND APPROVAL OF NOMINATED CERTIFIED REFERENCE MATERIALS AND REFERENCE MEASUREMENT METHODS/PROCEDURES JCTLM WG1-P-03 PROCESS FOR REVIEW AND APPROVAL OF NOMINATED CERTIFIED REFERENCE MATERIALS AND REFERENCE MEASUREMENT METHODS/PROCEDURES - PRIMARY AUTHORS NAME RICHARD R. MILLER CRAIG M. JACKSON FUNCTION MEMBER, PROCEDURES

More information

Corporate Governance Statement

Corporate Governance Statement Corporate Governance Statement Mesoblast Limited (the Company or Mesoblast) and its Board of Directors (the Board) are committed to implementing and achieving an effective corporate governance framework

More information

LOOKSMART, LTD. CORPORATE GOVERNANCE GUIDELINES

LOOKSMART, LTD. CORPORATE GOVERNANCE GUIDELINES LOOKSMART, LTD. CORPORATE GOVERNANCE GUIDELINES As ratified on 10/18/10 The board has developed corporate governance practices to help fulfill its responsibility to the shareholders. These practices are

More information

EMC CORPORATION. Corporate Governance Guidelines

EMC CORPORATION. Corporate Governance Guidelines EMC CORPORATION Corporate Governance Guidelines The following Corporate Governance Guidelines (the Guidelines ) have been adopted by the Board of Directors (the Board ) of EMC Corporation (the Company

More information

AUDIT AND RISK MANAGEMENT COMMITTEE CHARTER

AUDIT AND RISK MANAGEMENT COMMITTEE CHARTER MASTERMYNE GROUP LIMITED AUDIT AND RISK MANAGEMENT COMMITTEE CHARTER Purpose of Charter 1. The Audit and Risk Management Committee Charter (Charter) governs the operations of the Audit and Risk Management

More information

Voluntary Certification Scheme for Traditional Health Practitioner

Voluntary Certification Scheme for Traditional Health Practitioner ANNEX-3 Voluntary Certification Scheme for Traditional Health Practitioner 0. Introduction 0.1 This document defines the criteria to be followed by the bodies certifying persons against specific requirements,

More information

BOARD CHARTER. Its objectives are to: provide strategic guidance for the Company and effective oversight of management;

BOARD CHARTER. Its objectives are to: provide strategic guidance for the Company and effective oversight of management; BOARD CHARTER Objectives The Board is ultimately responsible for the oversight and review of the management, operations and overall corporate governance of the Company. Its objectives are to: provide strategic

More information

EMR ASM Alliance Executive Group: Terms of Reference

EMR ASM Alliance Executive Group: Terms of Reference EASTERN METROPOLITAN REGION ASM Alliance Executive Group TERMS OF REFERENCE The EMR ASM Alliance The EMR ASM Alliance has been created to support the implementation of the Active Service Model (ASM) across

More information

CORPORATE GOVERNANCE GUIDELINES. (Adopted as of June 2, 2014)

CORPORATE GOVERNANCE GUIDELINES. (Adopted as of June 2, 2014) CORPORATE GOVERNANCE GUIDELINES (Adopted as of June 2, 2014) The following corporate governance guidelines have been approved and adopted by the Board of Directors (the Board ) of Arista Networks, Inc.

More information

COHERENT, INC. Board of Directors. Governance Guidelines

COHERENT, INC. Board of Directors. Governance Guidelines COHERENT, INC. Board of Directors Governance Guidelines Effective: December 12, 2013 1. Mission of the Board The Board of Directors (the Board ) has the ultimate responsibility for the well being of the

More information

ATMAE Accreditation Accreditation Program Policies and Procedures January 21, 2013 Revisions, Sections 1 through 4

ATMAE Accreditation Accreditation Program Policies and Procedures January 21, 2013 Revisions, Sections 1 through 4 ATMAE Accreditation Accreditation Program Policies and Procedures (These revisions supersede and replace the 2009 ATMAE Accreditation Handbook, Sections 1 through 4) Table of Contents: Sections 1 through

More information

RECOMMENDED CHARTER FOR THE IDENTITY ECOSYSTEM STEERING GROUP

RECOMMENDED CHARTER FOR THE IDENTITY ECOSYSTEM STEERING GROUP RECOMMENDED CHARTER FOR THE IDENTITY ECOSYSTEM STEERING GROUP 1. Identity Ecosystem Steering Group Charter The National Strategy for Trusted Identities in Cyberspace (NSTIC or Strategy), signed by President

More information

Corporate Governance Guidelines

Corporate Governance Guidelines Corporate Governance Guidelines A. Introduction The Board of Directors (the Board ) of (the Company ) has adopted these corporate governance guidelines to provide a framework within which the Board may

More information

CORPORATE GOVERNANCE GUIDELINES

CORPORATE GOVERNANCE GUIDELINES CORPORATE GOVERNANCE GUIDELINES INTRODUCTION The Nominating and Corporate Governance Committee (the Governance Committee ) of the Board of Directors (the Board ) of Hilton Worldwide Holdings Inc. (the

More information

WOODBINE ENTERTAINMENT GROUP CORPORATE GOVERNANCE GUIDELINES

WOODBINE ENTERTAINMENT GROUP CORPORATE GOVERNANCE GUIDELINES WOODBINE ENTERTAINMENT GROUP CORPORATE GOVERNANCE GUIDELINES 1.0 Introduction The board of directors (the Board ) of Woodbine Entertainment Group ( WEG ) is committed to adhering to the highest possible

More information

Final Document. Title: IMDRF Standards Operating Procedures. Authoring Group: IMDRF Management Committee. Date: 17 December 2014

Final Document. Title: IMDRF Standards Operating Procedures. Authoring Group: IMDRF Management Committee. Date: 17 December 2014 IMDRF/MC/N2FINAL:2014 (Edition 2) Final Document Title: Authoring Group: IMDRF Standards Operating Procedures IMDRF Management Committee Date: 17 December 2014 Jeff Shuren, IMDRF Chair This document was

More information

BATS Global Markets, Inc. a Delaware corporation (the Company ) Corporate Governance Guidelines Adopted March 28, 2012

BATS Global Markets, Inc. a Delaware corporation (the Company ) Corporate Governance Guidelines Adopted March 28, 2012 BATS Global Markets, Inc. a Delaware corporation (the Company ) Corporate Governance Guidelines Adopted March 28, 2012 These guidelines have been approved and adopted by the Board of Directors of the Company

More information

GREAT PLAINS ENERGY INCORPORATED BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES. Amended: December 9, 2014

GREAT PLAINS ENERGY INCORPORATED BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES. Amended: December 9, 2014 GREAT PLAINS ENERGY INCORPORATED BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES Amended: December 9, 2014 Introduction The Board of Directors (the Board ) of Great Plains Energy Incorporated (the Company

More information

SEMPRA ENERGY. Corporate Governance Guidelines. As adopted by the Board of Directors of Sempra Energy and amended through September 12, 2014

SEMPRA ENERGY. Corporate Governance Guidelines. As adopted by the Board of Directors of Sempra Energy and amended through September 12, 2014 SEMPRA ENERGY Corporate Governance Guidelines As adopted by the Board of Directors of Sempra Energy and amended through September 12, 2014 I Role of the Board and Management 1.1 Board Oversight Sempra

More information

INTEGRATED SILICON SOLUTION, INC. CORPORATE GOVERNANCE PRINCIPLES. Effective January 9, 2015

INTEGRATED SILICON SOLUTION, INC. CORPORATE GOVERNANCE PRINCIPLES. Effective January 9, 2015 INTEGRATED SILICON SOLUTION, INC. CORPORATE GOVERNANCE PRINCIPLES Effective January 9, 2015 These principles have been adopted by the Board of Directors (the "Board") of Integrated Silicon Solution, Inc.

More information

ADOBE CORPORATE GOVERNANCE GUIDELINES

ADOBE CORPORATE GOVERNANCE GUIDELINES Contents 2 Introduction 2 The Mission of the Board of Directors 2 Guidelines for Corporate Governance ADOBE CORPORATE GOVERNANCE GUIDELINES 2 Selection of the Board 3 Board Leadership 3 Board Composition,

More information

PBS Hospital Medication Chart Reference Group. Terms of Reference

PBS Hospital Medication Chart Reference Group. Terms of Reference PBS Hospital Medication Chart Reference Group Terms of Reference Dec 2014 Table of Contents 1. Introduction... 3 2. Purpose... 3 3. Role and Function... 4 4. Composition... 4 5. Terms of Appointment...

More information

Suffolk Strategic Housing Partnership Terms of Reference

Suffolk Strategic Housing Partnership Terms of Reference Suffolk Strategic Housing Partnership Terms of Reference 1. The Vision 1.1 The Vision for the SSHP is to bring together the key housing stakeholders into one partnership to champion and promote the wider

More information

Strategic Advisory Group of Experts (SAGE) Terms of reference

Strategic Advisory Group of Experts (SAGE) Terms of reference Strategic Advisory Group of Experts (SAGE) Terms of reference Functions SAGE serves as the principal advisory group to the World Health Organization (WHO) for development of policy related to vaccines

More information

Procedures for Assessment and Accreditation of Medical Schools by the Australian Medical Council 2011

Procedures for Assessment and Accreditation of Medical Schools by the Australian Medical Council 2011 Australian Medical Council Limited Procedures for Assessment and Accreditation of Medical Schools by the Australian Medical Council 2011 Medical School Accreditation Committee These procedures were approved

More information

ASAE s Job Task Analysis Strategic Level Competencies

ASAE s Job Task Analysis Strategic Level Competencies ASAE s Job Task Analysis Strategic Level Competencies During 2013, ASAE funded an extensive, psychometrically valid study to document the competencies essential to the practice of association management

More information

Corporate Governance Guidelines Altria Group, Inc.

Corporate Governance Guidelines Altria Group, Inc. Corporate Governance Guidelines Altria Group, Inc. Table of Contents A. ROLE AND RESPONSIBILITY OF THE BOARD B. BOARD COMPOSITION, STRUCTURE AND POLICIES 1. Board Size 2. Independence of Directors 3. Annual

More information

Board Charter. May 2014

Board Charter. May 2014 May 2014 Document History and Version Control Document History Document Title: Board Charter Document Type: Charter Owner: Board [Company Secretary] Description of content: Corporate Governance practices

More information

NEW YORK LIFE INSURANCE COMPANY BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES

NEW YORK LIFE INSURANCE COMPANY BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES NEW YORK LIFE INSURANCE COMPANY BOARD OF DIRECTORS CORPORATE GOVERNANCE GUIDELINES The New York Life Insurance Company Board of Directors (the Board of Directors or Board ) recognizes its responsibility

More information

Contents. Abstract...i. Committee Membership... iii. Foreword... vii. 1 Scope...1

Contents. Abstract...i. Committee Membership... iii. Foreword... vii. 1 Scope...1 ISBN 1-56238-584-4 Volume 25 Number 27 ISSN 0273-3099 Interference Testing in Clinical Chemistry; Approved Guideline Second Edition Robert J. McEnroe, PhD Mary F. Burritt, PhD Donald M. Powers, PhD Douglas

More information

THE OPTIONS CLEARING CORPORATION BOARD OF DIRECTORS CORPORATE GOVERNANCE PRINCIPLES

THE OPTIONS CLEARING CORPORATION BOARD OF DIRECTORS CORPORATE GOVERNANCE PRINCIPLES THE OPTIONS CLEARING CORPORATION BOARD OF DIRECTORS CORPORATE GOVERNANCE PRINCIPLES The following Corporate Governance Principles have been adopted by the Board of Directors (the Board ) of The Options

More information

20. APPOINTMENT OF GRADUATE FACULTY AND THESIS AND DISSERTATION CHAIRS

20. APPOINTMENT OF GRADUATE FACULTY AND THESIS AND DISSERTATION CHAIRS DEPARTMENT OF ECONOMICS POLICY STATEMENT as approved October 26, 1996, and subsequently amended 11/21/2010 and resubmitted for approval on 4/20/2012. TABLE OF CONTENTS 1. DEFINITIONS 2. RULES 3. DEPARTMENT

More information

Audit, Business Risk and Compliance Committee Charter

Audit, Business Risk and Compliance Committee Charter Audit, Business Risk and Compliance Committee Charter Calibre Group Limited ABN 44 100 255 623 CGH162364/REV 1/2012 Adopted by the Board on 25 May 2012 1 Membership of the Committee The Committee must

More information

Doha Bank. Board of Directors Terms of Reference. Version 1.0

Doha Bank. Board of Directors Terms of Reference. Version 1.0 Doha Bank Board of Directors Terms of Reference Version 1.0 TABLE OF CONTENTS INTRODUCTION... 1 BOARD MEETINGS... 2 BOARD COMPOSITION... 4 ROLES AND RESPONSIBILITIES...5 BOARD COMMITTEES... 11 BOARD MEMBERSHIP...15

More information

INSTITUTIONAL QUALITY ASSURANCE POLICY

INSTITUTIONAL QUALITY ASSURANCE POLICY INSTITUTIONAL QUALITY ASSURANCE POLICY Approval: Responsibility: Contact Office: University Senate; Ontario Universities Council on Quality Assurance (Quality Council) Provost and Vice President Academic

More information

Tenure and Promotion Criteria and Procedures Department of Computer Science and Engineering University of South Carolina, Columbia, SC 29208

Tenure and Promotion Criteria and Procedures Department of Computer Science and Engineering University of South Carolina, Columbia, SC 29208 Tenure and Promotion Criteria and Procedures Department of Computer Science and Engineering University of South Carolina, Columbia, SC 29208 UCTP Approval: February 20, 2002 Recommendations of the tenured

More information

Connecticut Multicultural Health Partnership. Bylaws

Connecticut Multicultural Health Partnership. Bylaws Connecticut Multicultural Health Partnership Bylaws ARTICLE 1. NAME The name of the organization shall be the Connecticut Multicultural Health Partnership, hereinafter called "the Partnership." The Partnership

More information

EDISON INTERNATIONAL CORPORATE GOVERNANCE GUIDELINES. Adopted by the Board of Directors. February 26, 2015

EDISON INTERNATIONAL CORPORATE GOVERNANCE GUIDELINES. Adopted by the Board of Directors. February 26, 2015 EDISON INTERNATIONAL CORPORATE GOVERNANCE GUIDELINES Adopted by the Board of Directors February 26, 2015 These Corporate Governance Guidelines reflect current policies of the Board of Directors for the

More information

Guidelines for applicants

Guidelines for applicants ERACoSysMed 1st Joint Transnational Call for Proposals for European Research Projects to demonstrate the feasibility and benefits of systems medicine Guidelines for applicants Submission deadline for pre-proposals:

More information

Due Process for the GRI Reporting Framework

Due Process for the GRI Reporting Framework Introduction 1. All documents in the GRI Framework must be developed in accordance with the due process principles approved by the GRI Board of Directors and outlined in this document. The Technical Advisory

More information

MAXIM INTEGRATED PRODUCTS, INC. CORPORATE GOVERNANCE GUIDELINES. (Adopted by the Board of Directors on April 6, 2007)

MAXIM INTEGRATED PRODUCTS, INC. CORPORATE GOVERNANCE GUIDELINES. (Adopted by the Board of Directors on April 6, 2007) MAXIM INTEGRATED PRODUCTS, INC. CORPORATE GOVERNANCE GUIDELINES (Adopted by the Board of Directors on April 6, 2007) The following guidelines have been approved by the Board of Directors (the Board ) of

More information

Corporate Governance Guidelines

Corporate Governance Guidelines Corporate Governance Guidelines IDEXX Laboratories, Inc. Introduction The Board of Directors (the Board ) of IDEXX Laboratories, Inc. (the Company ) has adopted the following Corporate Governance Guidelines

More information

Introduction. Board Structure and Composition CORPORATE GOVERNANCE GUIDELINES

Introduction. Board Structure and Composition CORPORATE GOVERNANCE GUIDELINES CORPORATE GOVERNANCE GUIDELINES Introduction The Board of Directors of Rocket Fuel Inc. has established these Corporate Governance guidelines to provide a framework within which our directors and management

More information

THE GAP, INC. CORPORATE GOVERNANCE GUIDELINES (As of February 1, 2015)

THE GAP, INC. CORPORATE GOVERNANCE GUIDELINES (As of February 1, 2015) THE GAP, INC. CORPORATE GOVERNANCE GUIDELINES (As of February 1, 2015) The board has developed corporate governance practices to help fulfill its responsibility to the shareholders. These practices are

More information

BAXALTA INCORPORATED Corporate Governance Guidelines

BAXALTA INCORPORATED Corporate Governance Guidelines Effective as of July 1, 2015 BAXALTA INCORPORATED Corporate Governance Guidelines The Board of Directors of Baxalta Incorporated ( Baxalta or the Company including its subsidiaries) recognizes the importance

More information

OVERVIEW OF THE PREQUALIFICATION OF DIAGNOSTICS ASSESSMENT PROCESS. Prequalification of Diagnostics

OVERVIEW OF THE PREQUALIFICATION OF DIAGNOSTICS ASSESSMENT PROCESS. Prequalification of Diagnostics D i a g n o s t i c s a n d L a b o r a t o r y T e c h n o l o g y OVERVIEW OF THE PREQUALIFICATION OF DIAGNOSTICS ASSESSMENT PROCESS Prequalification of Diagnostics PQDx_007 v3 20 April 2010 Table of

More information

CHAPTER 5 STAKEHOLDERS: THEIR INTERESTS, CONCERNS, AND RESPONSIBILITIES

CHAPTER 5 STAKEHOLDERS: THEIR INTERESTS, CONCERNS, AND RESPONSIBILITIES CHAPTER 5 STAKEHOLDERS: THEIR INTERESTS, CONCERNS, AND RESPONSIBILITIES Key Points: Each worker study involves multiple stakeholders in addition to the researcher and worker. Stakeholders interests in

More information

BOARD CHARTER Link Administration Holdings Limited ("Company") ABN 27 120 964 098

BOARD CHARTER Link Administration Holdings Limited (Company) ABN 27 120 964 098 1. Role of the Board BOARD CHARTER Link Administration Holdings Limited ("Company") ABN 27 120 964 098 This Board Charter sets out the principles for the operation of the board of directors of the Company

More information

Major Science Initiatives Fund competition 2017 2022. Draft Call for Proposals for consultation

Major Science Initiatives Fund competition 2017 2022. Draft Call for Proposals for consultation Major Science Initiatives Fund competition 2017 2022 Draft Call for Proposals for consultation September 2015 CONTENTS COMPETITION DESCRIPTION... 4 Background... 4 Objectives... 4 National research facility

More information

The University of Toledo College of Medicine and Life Sciences Faculty Tracks for Academic Rank and Criteria for Promotion

The University of Toledo College of Medicine and Life Sciences Faculty Tracks for Academic Rank and Criteria for Promotion The University of Toledo College of Medicine and Life Sciences Faculty Tracks for Academic Rank and Criteria for Promotion Faculty Tracks for Academic Rank. There are six tracks for full-time and part-time

More information

2.2 Assessors shall not be members of Boards or Joint Boards of Examiners and shall not be entitled unless invited to attend their meetings.

2.2 Assessors shall not be members of Boards or Joint Boards of Examiners and shall not be entitled unless invited to attend their meetings. Regulations for the Examination of Master s Level Degrees 1 Appointment of Examiners 1 Definition of Terms Used: Examiners 1.1 Members of Boards of Examiners shall be designated as Examiners, as follows:

More information

The size and composition of the Board is to be determined from time to time by the Board itself in an effort to balance the following goals:

The size and composition of the Board is to be determined from time to time by the Board itself in an effort to balance the following goals: AMERICAN INTERNATIONAL GROUP, INC. CORPORATE GOVERNANCE GUIDELINES (Effective March 11, 2015) I. INTRODUCTION The Board of Directors (the Board ) of American International Group, Inc. ( AIG ), acting on

More information

Committee Approved: January 6, 2014 FNC Board Approved: January 8, 2014. Compensation and Governance Committee Charter

Committee Approved: January 6, 2014 FNC Board Approved: January 8, 2014. Compensation and Governance Committee Charter Committee Approved: January 6, 2014 FNC Board Approved: January 8, 2014 Compensation and Governance Committee Charter Page 2 of 5 I. PURPOSE The Board of Directors of First National Corporation (the Board

More information

Infinity Federal Credit Union. Governance Policy. Table of Contents. Introduction.. 2. Corporate Governance Policy Statement 2

Infinity Federal Credit Union. Governance Policy. Table of Contents. Introduction.. 2. Corporate Governance Policy Statement 2 Infinity Federal Credit Union Governance Policy Table of Contents Page Introduction.. 2 Corporate Governance Policy Statement 2 Roles and Responsibilities of the Board and Management 2 Board Committees.

More information

Guidance Note: Corporate Governance - Board of Directors. March 2015. Ce document est aussi disponible en français.

Guidance Note: Corporate Governance - Board of Directors. March 2015. Ce document est aussi disponible en français. Guidance Note: Corporate Governance - Board of Directors March 2015 Ce document est aussi disponible en français. Applicability The Guidance Note: Corporate Governance - Board of Directors (the Guidance

More information

Healthy Sacramento Coalition Operating Guidelines and Procedures

Healthy Sacramento Coalition Operating Guidelines and Procedures Healthy Sacramento Coalition Operating Guidelines and Procedures Established 09/2012 Last Revised 9/30/2014 I. VISION The Healthy Sacramento Coalition Envisions a County that is Healthy, Safe and Thriving.

More information

Role of IRB/IEC in GCP. Benjamin Kuo, MD, Dr.PH, CIP.

Role of IRB/IEC in GCP. Benjamin Kuo, MD, Dr.PH, CIP. Role of IRB/IEC in GCP Benjamin Kuo, MD, Dr.PH, CIP. Institutional Review Board (IRB) An independent body constituted of medical, scientific and non scientific members Responsible for ensuring protection

More information

National Commission for Academic Accreditation & Assessment. Standards for Quality Assurance and Accreditation of Higher Education Institutions

National Commission for Academic Accreditation & Assessment. Standards for Quality Assurance and Accreditation of Higher Education Institutions National Commission for Academic Accreditation & Assessment Standards for Quality Assurance and Accreditation of Higher Education Institutions November 2009 Standards for Institutional Accreditation in

More information

CORPORATE GOVERNANCE - BOARD CHARTER PART A DEFINING GOVERNANCE ROLES

CORPORATE GOVERNANCE - BOARD CHARTER PART A DEFINING GOVERNANCE ROLES CORPORATE GOVERNANCE - BOARD CHARTER PART A DEFINING GOVERNANCE ROLES 1. ROLE OF THE BOARD 1.1 Function The Board of Directors of Exalt Resources Limited have approved the following charter formalising

More information

NCR Corporation Board of Directors Corporate Governance Guidelines Revised January 20, 2016

NCR Corporation Board of Directors Corporate Governance Guidelines Revised January 20, 2016 NCR Corporation Board of Directors Corporate Governance Guidelines Revised January 20, 2016 NCR s Board of Directors is elected by the stockholders to govern the affairs of the Company. The Board selects

More information

CITRIX SYSTEMS, INC. CORPORATE GOVERNANCE GUIDELINES

CITRIX SYSTEMS, INC. CORPORATE GOVERNANCE GUIDELINES CITRIX SYSTEMS, INC. CORPORATE GOVERNANCE GUIDELINES Set forth below are Citrix Systems, Inc. s corporate governance policies. These guidelines are subject to change from time to time at the direction

More information

IMMUNOGEN, INC. CORPORATE GOVERNANCE GUIDELINES OF THE BOARD OF DIRECTORS

IMMUNOGEN, INC. CORPORATE GOVERNANCE GUIDELINES OF THE BOARD OF DIRECTORS IMMUNOGEN, INC. CORPORATE GOVERNANCE GUIDELINES OF THE BOARD OF DIRECTORS Introduction As part of the corporate governance policies, processes and procedures of ImmunoGen, Inc. ( ImmunoGen or the Company

More information

MUTUAL OF OMAHA INSURANCE COMPANY CORPORATE GOVERNANCE STANDARDS

MUTUAL OF OMAHA INSURANCE COMPANY CORPORATE GOVERNANCE STANDARDS MUTUAL OF OMAHA INSURANCE COMPANY CORPORATE GOVERNANCE STANDARDS The Board of Mutual of Omaha Insurance Company (the Corporation ) has adopted these corporate governance standards to further its longstanding

More information

El Paso Electric Company A Texas corporation (the Company ) Corporate Governance Guidelines. 1. Composition of the Board and Board Membership Criteria

El Paso Electric Company A Texas corporation (the Company ) Corporate Governance Guidelines. 1. Composition of the Board and Board Membership Criteria El Paso Electric Company A Texas corporation (the Company ) Corporate Governance Guidelines As Amended September 28, 2015, November 20, 2014, November 18, 2010, March 2, 2007 and September 15, 2005 Originally

More information

Peninsular Florida Landscape Conservation Cooperative. Charter. Background

Peninsular Florida Landscape Conservation Cooperative. Charter. Background Charter Background The Peninsular Florida Landscape Conservation Cooperative (Conservation Cooperative) is part of a national network of Landscape Conservation Cooperatives (LCCs). LCCs are applied conservation

More information

PROJECT AUDIENCE REQUEST FOR PROPOSAL: Business Plan

PROJECT AUDIENCE REQUEST FOR PROPOSAL: Business Plan CONTENTS Introduction Proposal Submission deadline Background Summary of Goals Project Details o Business Plan Participants Financial Planning o Business structure/leadership model Framework Board governance/structure

More information

Financial Management Framework >> Overview Diagram

Financial Management Framework >> Overview Diagram June 2012 The State of Queensland (Queensland Treasury) June 2012 Except where otherwise noted you are free to copy, communicate and adapt this work, as long as you attribute the authors. This document

More information

CORPORATE GOVERNANCE GUIDELINES

CORPORATE GOVERNANCE GUIDELINES CORPORATE GOVERNANCE GUIDELINES The term "Corporation" refers to Pembina Pipeline Corporation, the term "Pembina" refers collectively to the Corporation and all entities controlled by the Corporation,

More information

Finding the Right People for Your Program Evaluation Team: Evaluator and Planning Team Job Descriptions

Finding the Right People for Your Program Evaluation Team: Evaluator and Planning Team Job Descriptions : Evaluator and Planning Team Job Descriptions I. Overview II. Sample Evaluator Job Description III. Evaluator Competencies IV. Recruiting members of your strategic evaluation planning team V. Recruiting

More information

INTUITIVE SURGICAL, INC. CORPORATE GOVERNANCE GUIDELINES

INTUITIVE SURGICAL, INC. CORPORATE GOVERNANCE GUIDELINES INTUITIVE SURGICAL, INC. CORPORATE GOVERNANCE GUIDELINES The Board of Directors (the Board ) of Intuitive Surgical, Inc., a Delaware corporation (the Company ), has adopted the following Corporate Governance

More information

Appendix 14 CORPORATE GOVERNANCE CODE AND CORPORATE GOVERNANCE REPORT

Appendix 14 CORPORATE GOVERNANCE CODE AND CORPORATE GOVERNANCE REPORT Appendix 14 CORPORATE GOVERNANCE CODE AND CORPORATE GOVERNANCE REPORT The Code This Code sets out the principles of good corporate governance, and two levels of recommendations: code provisions; and recommended

More information

Corporate Governance Guidelines

Corporate Governance Guidelines Corporate Governance Guidelines The Board of Directors (the Board ) of Och-Ziff Capital Management Group LLC (the Company ) has adopted the following Corporate Governance Guidelines as a framework for

More information

Sustainable Growth Rate (SGR) Repeal and Replace: Comparison of 2014 and 2015 Legislation

Sustainable Growth Rate (SGR) Repeal and Replace: Comparison of 2014 and 2015 Legislation Sustainable Growth Rate (SGR) Repeal and Replace: Comparison of 2014 and 2015 Legislation Proposal 113 th Congress - - H.R.4015/S.2000 114 th Congress - - H.R.1470 SGR Repeal and Annual Updates General

More information

Graduate Group in Nursing Science & Health-Care Leadership Bylaws ARTICLE I. OBJECTIVE Discipline: Mission:

Graduate Group in Nursing Science & Health-Care Leadership Bylaws ARTICLE I. OBJECTIVE Discipline: Mission: Graduate Group in Nursing Science & Health-Care Leadership Bylaws Administrative Home: Betty Irene Moore School of Nursing Approved by Graduate Council: May 6, 2009 ARTICLE I. OBJECTIVE The Nursing Science

More information

Stakeholder Guide 2014 www.effectivehealthcare.ahrq.gov

Stakeholder Guide 2014 www.effectivehealthcare.ahrq.gov Stakeholder Guide 2014 www.effectivehealthcare.ahrq.gov AHRQ Publication No. 14-EHC010-EF Replaces Publication No. 11-EHC069-EF February 2014 Effective Health Care Program Stakeholder Guide Contents Introduction...1

More information

BYLAWS OF THE AASHTO TRANSPORTATION CURRICULUM COORDINATION COUNCIL

BYLAWS OF THE AASHTO TRANSPORTATION CURRICULUM COORDINATION COUNCIL BYLAWS OF THE AASHTO TRANSPORTATION CURRICULUM COORDINATION COUNCIL MAY 26, ARTICLE I NAME AND MISSION Section 1 Name. The name of the AASHTO (American Association of State Highway and Transportation Officials)

More information

The Rubicon Project, Inc. Corporate Governance Guidelines

The Rubicon Project, Inc. Corporate Governance Guidelines The Rubicon Project, Inc. Corporate Governance Guidelines These Corporate Governance Guidelines reflect the corporate governance practices established by the Board of Directors (the Board ) of The Rubicon

More information

Corporate Governance Principles. February 23, 2015

Corporate Governance Principles. February 23, 2015 Corporate Governance Principles February 23, 2015 The Board of Directors (the Board ) of The Boeing Company ( Boeing or the Company ) has adopted the following corporate governance principles (the Principles

More information

The Kroger Co. Board of Directors. Guidelines on Issues of Corporate Governance. (Rev. 5/11/15)

The Kroger Co. Board of Directors. Guidelines on Issues of Corporate Governance. (Rev. 5/11/15) The Kroger Co. Board of Directors Guidelines on Issues of Corporate Governance (Rev. 5/11/15) THE KROGER CO. BOARD OF DIRECTORS GUIDELINES ON ISSUES OF CORPORATE GOVERNANCE The Kroger Co. Board of Directors

More information

CONSTITUTION COLLEGE OF ENGINEERING UNIVERSITY OF FLORIDA PREAMBLE

CONSTITUTION COLLEGE OF ENGINEERING UNIVERSITY OF FLORIDA PREAMBLE CONSTITUTION COLLEGE OF ENGINEERING UNIVERSITY OF FLORIDA This Constitution is intended to be consistent with Florida law, the University Constitution and the regulations of the University of Florida Board

More information

WAL-MART STORES, INC. CORPORATE GOVERNANCE GUIDELINES

WAL-MART STORES, INC. CORPORATE GOVERNANCE GUIDELINES WAL-MART STORES, INC. CORPORATE GOVERNANCE GUIDELINES The following Corporate Governance Guidelines have been adopted by the Board of Directors (the Board ) of Wal-Mart Stores, Inc. (the Company ) to assist

More information

Colorado Integrated Criminal Justice Information System (CICJIS) Program CHARTER and BYLAWS

Colorado Integrated Criminal Justice Information System (CICJIS) Program CHARTER and BYLAWS Colorado Integrated Criminal Justice Information System (CICJIS) Program CHARTER and BYLAWS Program Description The Colorado Integrated Criminal Justice Information System (CICJIS) Program is a complex

More information

CORPORATE GOVERNANCE GUIDELINES OF PERFORMANCE FOOD GROUP COMPANY

CORPORATE GOVERNANCE GUIDELINES OF PERFORMANCE FOOD GROUP COMPANY CORPORATE GOVERNANCE GUIDELINES OF PERFORMANCE FOOD GROUP COMPANY The Board of Directors is committed to achieving business success and enhancing longterm shareholder value while maintaining the highest

More information

ISS Institutional Shareholder Services Inc.

ISS Institutional Shareholder Services Inc. ISS Compliance Statement to Japan s Stewardship Code August 2014 ISS is pleased to submit the following Compliance Statement to Principles for Responsible Institutional Investors, Japan s Stewardship Code

More information

Wolverine World Wide, Inc. Corporate Governance Guidelines

Wolverine World Wide, Inc. Corporate Governance Guidelines Wolverine World Wide, Inc. Corporate Governance Guidelines The following Corporate Governance Guidelines have been approved by the Board of Directors (the Board ) of Wolverine World Wide, Inc. ( Wolverine

More information

STATEMENT OF VALUES AND CODE OF ETHICS

STATEMENT OF VALUES AND CODE OF ETHICS STATEMENT OF VALUES AND CODE OF ETHICS INTRODUCTION The Smithsonian Institution is a public trust whose mission is the increase and diffusion of knowledge. The Smithsonian was established by the United

More information

CALIFORNIA GIS COUNCIL CHARTER

CALIFORNIA GIS COUNCIL CHARTER CALIFORNIA GIS COUNCIL CHARTER ADOPTED JANUARY 7, 2015 SECTION 1: FINDING AND DECLARATIONS WHEREAS: A. Geographic Information Systems (GIS) are a critical tool for improving the quality, accuracy and responsiveness

More information

HK Electric Investments Limited

HK Electric Investments Limited HK Electric Investments Limited 港 燈 電 力 投 資 有 限 公 司 (Incorporated in the Cayman Islands with limited liability) together with HK Electric Investments (Stock Code: 2638) 1. Membership AUDIT COMMITTEE TERMS

More information

Canada Media Fund/Fonds des médias du Canada

Canada Media Fund/Fonds des médias du Canada Canada Media Fund/Fonds des médias du Canada Statement of Corporate Governance Principles I. Introduction The Corporation s mandate is to champion the creation of successful, innovative Canadian content

More information

Research IT Governance Handbook

Research IT Governance Handbook Research IT Governance Handbook Initial Version: May 8, 2015 1 Clarifications added June 8, 2015, for 1) role of VPR in reviewing and disseminating decisions of the AC and EC, and 2) step in working groups

More information

Procedure Terms of reference of the support structure of the CDM Executive Board

Procedure Terms of reference of the support structure of the CDM Executive Board CLEAN DEVELOPMENT MECHANISM CDM-EB61-A01-PROC Procedure Terms of reference of the support structure of the CDM Executive Board TABLE OF CONTENTS Page 1. INTRODUCTION... 3 2. GENERAL GUIDELINES... 3 2.1.

More information

UNIVERSITY OF SOUTH CAROLINA

UNIVERSITY OF SOUTH CAROLINA UNIVERSITY OF SOUTH CAROLINA College of Nursing Approved UCTP April 6, 2011 1 Criteria and Procedures for Tenure and Promotion Review, Post Tenure Review and Tenure Track and Tenured Faculty Annual Review

More information

RALLY SOFTWARE DEVELOPMENT CORP. CORPORATE GOVERNANCE GUIDELINES

RALLY SOFTWARE DEVELOPMENT CORP. CORPORATE GOVERNANCE GUIDELINES RALLY SOFTWARE DEVELOPMENT CORP. CORPORATE GOVERNANCE GUIDELINES The Board of Directors (the Board ) of Rally Software Development Corp. ( Rally ) has established the following guidelines for the conduct

More information

Immune Therapeutics. Corporate Governance Guidelines.

Immune Therapeutics. Corporate Governance Guidelines. Immune Therapeutics Corporate Governance Guidelines The Board of Directors has adopted these Guidelines in order to reflect the Company s commitment to good corporate governance. The Board believes that

More information

St Johns County CoC Governance Charter St Johns County Continuum of Care St Johns County Continuum of Care Board Purpose of the CoC and CoC Board

St Johns County CoC Governance Charter St Johns County Continuum of Care St Johns County Continuum of Care Board Purpose of the CoC and CoC Board St Johns County CoC Governance Charter The name of this Continuum of Care (CoC) shall be the St Johns County Continuum of Care and the name of the CoC board shall be the St Johns County Continuum of Care

More information

FIVE STAR QUALITY CARE, INC. GOVERNANCE GUIDELINES

FIVE STAR QUALITY CARE, INC. GOVERNANCE GUIDELINES FIVE STAR QUALITY CARE, INC. GOVERNANCE GUIDELINES Adopted March 1, 2016 The following Governance Guidelines (the Guidelines ) have been adopted by the Board of Directors (the Board ) of Five Star Quality

More information

Policy of the National Institute of Nursing Research for Data and Safety Monitoring of Extramural Clinical Trials

Policy of the National Institute of Nursing Research for Data and Safety Monitoring of Extramural Clinical Trials Policy of the National Institute of Nursing Research for Data and Safety Monitoring of Extramural Clinical Trials Purpose and Scope This policy sets forth the National Institute of Nursing Research (NINR)

More information

MONDELĒZ INTERNATIONAL, INC. Corporate Governance Guidelines

MONDELĒZ INTERNATIONAL, INC. Corporate Governance Guidelines MONDELĒZ INTERNATIONAL, INC. Corporate Governance Guidelines A. ROLE AND RESPONSIBILITY OF THE BOARD The Board of Directors (the "Board") primary responsibility is to foster Mondelēz International Inc.

More information

3 rd Edition of the Common Academic Regulations for t he D egree o f S eni o r D o c t o r a t e of the Uni ve r s i ty of Wal e s

3 rd Edition of the Common Academic Regulations for t he D egree o f S eni o r D o c t o r a t e of the Uni ve r s i ty of Wal e s 3 rd Edition of the Common Academic Regulations for t he D egree o f S eni o r D o c t o r a t e of the Uni ve r s i ty of Wal e s Eligibility 2 Definition of Published Work, Production or Artefact 3 Quantity

More information