Standard Medicare Part D* checklist

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1 Standard Medicare Part D* checklist This checklist can help you receive Sensipar (cinacalcet) at the lowest possible cost. You can use this checklist if you: Have Standard Medicare Part D* prescription insurance Have been prescribed Sensipar Step completed Step description Your health care professional will submit a Prior Authorization form, if required Discuss the Standard Medicare Part D* benefit with your health care professional Use the Medicare Part D calculator at AmgenAssist.com to learn about Standard Medicare Part D* coverage Standard Medicare Part D* includes the donut hole coverage gap Discuss available grants from an independent co-pay foundation with your health care professional Use the Medicare Part D calculator at AmgenAssist.com to see how an independent co-pay foundation may be able to help you lower the cost of Sensipar if you qualify Apply for a grant from an independent co-pay foundation Talk to your health care professional to see if you qualify Provide the necessary form(s) to your health care professional Fill your Sensipar prescription Tell your health care professional that you received your Sensipar If you have any problems filling your Sensipar (cinacalcet) prescription, discuss it with the dialysis staff at your next session. * Standard Medicare Part D includes those who have purchased a Part D prescription plan but who have sufficient assets or income that disqualify them from receiving Medicaid or the low-income subsidy (LIS). Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis.

2 Indication Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis. Important Safety Information Sensipar treatment should not be initiated if serum calcium is less than the lower limit of the normal range (8.4 mg/dl). Sensipar lowers serum calcium; therefore, it is important that patients are carefully monitored for the occurrence of hypocalcemia. Significant reductions in calcium may lower the threshold for seizures. Secondary hyperparathyroidism (HPT) patients, particularly those with a history of seizure disorder, should be carefully monitored for the occurrence of low serum calcium or symptoms of hypocalcemia. In Sensipar postmarketing use, isolated, idiosyncratic cases of hypotension, worsening heart failure, and/or arrhythmia were reported in patients with impaired cardiac function. The causal relationship to Sensipar therapy could not be completely excluded and may be mediated by reductions in serum calcium levels. Adynamic bone disease may develop if intact parathyroid hormone (ipth) levels are suppressed below 100 pg/ml. Patients with moderate to severe hepatic impairment should be monitored throughout treatment with Sensipar, as cinacalcet exposure assessed by area under the curve (AUC) was higher than in patients with normal hepatic function. Serum calcium and serum phosphorus should be measured within 1 week and PTH should be measured 1 to 4 weeks after initiation or dose adjustment of Sensipar. Once the maintenance dose has been established, serum calcium and serum phosphorus should be measured approximately monthly, and PTH every 1 to 3 months. The most commonly reported side effects were nausea, vomiting, and diarrhea.

3 Commercial insurance checklist This checklist can help you receive Sensipar (cinacalcet) at the lowest possible cost. You can use this checklist if you: Have commercial* prescription insurance Have been prescribed Sensipar Step completed Step description Your health care professional will submit a Prior Authorization form, if required Visit the Sensipar support programs page at AmgenAssist.com to learn about the Sensipar Pharmacy Card The Sensipar Pharmacy Card can lower your Sensipar co-pay to $5.00, if you qualify Apply for the Sensipar Pharmacy Card Talk to your health care professional to see if you qualify Provide the necessary form(s) to your health care professional Activate your Sensipar Pharmacy Card Fill your Sensipar prescription Tell your health care professional that you received your Sensipar If your Sensipar (cinacelcet) co-pay is more than $5.00 or you have any problems filling your prescription, discuss it with the dialysis staff at your next session. * The commercial section includes federal employees and those patients receiving insurance benefits through Veterans Affairs/Department of Defense. Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis.

4 Indication Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis. Important Safety Information Sensipar treatment should not be initiated if serum calcium is less than the lower limit of the normal range (8.4 mg/dl). Sensipar lowers serum calcium; therefore, it is important that patients are carefully monitored for the occurrence of hypocalcemia. Significant reductions in calcium may lower the threshold for seizures. Secondary hyperparathyroidism (HPT) patients, particularly those with a history of seizure disorder, should be carefully monitored for the occurrence of low serum calcium or symptoms of hypocalcemia. In Sensipar postmarketing use, isolated, idiosyncratic cases of hypotension, worsening heart failure, and/or arrhythmia were reported in patients with impaired cardiac function. The causal relationship to Sensipar therapy could not be completely excluded and may be mediated by reductions in serum calcium levels. Adynamic bone disease may develop if intact parathyroid hormone (ipth) levels are suppressed below 100 pg/ml. Patients with moderate to severe hepatic impairment should be monitored throughout treatment with Sensipar, as cinacalcet exposure assessed by area under the curve (AUC) was higher than in patients with normal hepatic function. Serum calcium and serum phosphorus should be measured within 1 week and PTH should be measured 1 to 4 weeks after initiation or dose adjustment of Sensipar. Once the maintenance dose has been established, serum calcium and serum phosphorus should be measured approximately monthly, and PTH every 1 to 3 months. The most commonly reported side effects were nausea, vomiting, and diarrhea.

5 Medicare Part D* with Low-Income Subsidy (LIS) checklist This checklist can help you receive Sensipar (cinacalcet) at the lowest possible cost. You can use this checklist if you: Have Standard Medicare Part D* prescription insurance and you qualify for the Low-Income Subsidy Have been prescribed Sensipar Step completed Step description Your health care professional will submit a Prior Authorization form, if required Discuss the co-pay for your Sensipar with your health care professional Your co-pay for Sensipar should be $6.50 or less You will not fall into the donut hole coverage gap Fill your Sensipar prescription Tell your health care professional that you received your Sensipar If your Sensipar (cinacalcet) prescription is denied at the pharmacy or your co-pay is more than $6.50, discuss it with the dialysis staff at your next session. * Standard Medicare Part D includes those who have purchased a Part D prescription plan but who have sufficient assets or income that disqualify them from receiving Medicaid or the low-income subsidy (LIS). Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis.

6 Indication Sensipar (cinacalcet) is indicated for the treatment of secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis. Important Safety Information Sensipar treatment should not be initiated if serum calcium is less than the lower limit of the normal range (8.4 mg/dl). Sensipar lowers serum calcium; therefore, it is important that patients are carefully monitored for the occurrence of hypocalcemia. Significant reductions in calcium may lower the threshold for seizures. Secondary hyperparathyroidism (HPT) patients, particularly those with a history of seizure disorder, should be carefully monitored for the occurrence of low serum calcium or symptoms of hypocalcemia. In Sensipar postmarketing use, isolated, idiosyncratic cases of hypotension, worsening heart failure, and/or arrhythmia were reported in patients with impaired cardiac function. The causal relationship to Sensipar therapy could not be completely excluded and may be mediated by reductions in serum calcium levels. Adynamic bone disease may develop if intact parathyroid hormone (ipth) levels are suppressed below 100 pg/ml. Patients with moderate to severe hepatic impairment should be monitored throughout treatment with Sensipar, as cinacalcet exposure assessed by area under the curve (AUC) was higher than in patients with normal hepatic function. Serum calcium and serum phosphorus should be measured within 1 week and PTH should be measured 1 to 4 weeks after initiation or dose adjustment of Sensipar. Once the maintenance dose has been established, serum calcium and serum phosphorus should be measured approximately monthly, and PTH every 1 to 3 months. The most commonly reported side effects were nausea, vomiting, and diarrhea.

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