1 THINGS TO BE AWARE OF ABOUT PROSTATE AND LUNG CANCER Lawrence Lackey Jr., M.D. Internal Medicine 6001 W. Outer Dr. Ste 114
2 WHAT IS CANCER? The body is made up of hundreds of millions of living cells. Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person's life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries.
3 WHAT IS CANCER? Cancer begins when cells in a part of the body start to grow out of control. There are many kinds of cancer, but they all start because of outof-control growth of abnormal cells.
4 WHAT IS CANCER? Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. Cancer cells can also invade (grow into) other tissues, something that normal cells cannot do. Growing out of control and invading other tissues are what makes a cell a cancer cell.
5 WHAT IS CANCER SCREENING? Clinical testing designed to identify the presence of a specific cancer in an asymptomatic individual or population thought to be at risk of that specific cancer. The intent is to find cancers at the earliest possible stage in their development, in order to improve the chances for disease cure.
6 The best results for cancer screening are in: Colorectal cancer Cervical cancer Breast cancer
7 PROSTATE CANCER EPIDEMIOLOGY: Prostate cancer is the most common cancer in men and the 2nd most common cause of cancer deaths in men Life time risk for men in the U.S. of getting cancer is one out of six. Lifetime risk of a man dying of prostate cancer is one out of 30 There were approximately 220,000 new cases of prostate cancer diagnosed in the U.S. in 2008, with about 27,000 deaths in the U.S. annually.
8 Increasing age Ethnicity RISK FACTORS: Highest in African-American males Next highest in U.S. Caucasian males Lowest in Asian-American males First degree relatives A man with a father or brother with prostate cancer has an approximate 2x increase of developing prostate cancer.
9 RISK FACTORS: First degree relatives A man with a father or brother with prostate cancer has an approximate 2x increase of developing prostate cancer. Diet?? A high fat and low veggie diet may slightly increase the risk of prostate cancer The most recent trials have not shown selenium and Vitamin E not to increase survival Lycopenes (found in tomatoes) may be beneficial
10 RISK FACTORS: BPH and Prostatitis Chronic BPH and prostatitis appear to slightly increase the risk of the development of prostate cancer. Thus diagnosis and treatment of these conditions could make a difference Let your physician know if you have persistence of any of these symptoms: Decreased urinary stream Frequent urinating at night Dribbling at the end of urination Incomplete urination A split urinary stream
11 PSA SCREENING (controversial) ACP/ASIM USPSTF ACS American Urological Society
12 DIAGNOSIS AND PROGNOSIS: Digital rectal exam PSA, PSA velocity, free PSA, PSA density Plus TNM Stage Plus Gleason Score
13 TREATMENT: Options for no treatment Surgery (usually robotic) for early stage disease Radiation therapy Anti-androgen therapy Chemotherapy
14 LUNG CANCER EPIDEMIOLOGY: The leading cause of cancer death in the U.S. for both men and women In 2008, there were 213,000 new cases of lung cancer diagnosed in the U.S. 115, 000 cases were men 99,000 cases were women though breast cancer is the most common cancer in women, lung cancer is the #1 cause of cancer death in women. Approximately 70% of patients were over the age of 65, while less than 3% were under the age of 45
15 LUNG CANCER Overall, this cancer has a very poor prognosis. Only approximately 14% of patients live greater than 5 years. Despite this prognosis, there are long term survivors. Based on cancer registries there are, to date, 330,000 long term survivors.
16 RISK FACTORS: Cigarette smoking About 95% of lung cancers in men are caused by cigarette smoking About 80% of lung cancers in women are caused by cigarette smoking Passive smoking There is supportive evidence (though not level A) that there is some increased risk of lung cancer associated with passive cigarette smoke inhalation.
17 RISK FACTORS: Radon About 15,000 annual lung cancer deaths are attributed to radon Basements have the highest radon levels, and the EPA recommends initial testing Occupational exposure (i.e. asbestos, etc)
18 SCREENING: Currently there are no successful screening modalities Yearly spiral CT scans can pick up smaller more curable lesions. A recent clinical trial, demonstrated that earlier detection did not translate into increased survival or even in decreased number of advanced lung cancers in the screened group
19 CLINICAL PRESENTATION (i.e. things to look out for) Persistent cough esp. if associated with: Wheezing Coughing up blood Shortness or breath Persistent hoarseness (recurrent laryngeal nerve)
20 Unexplained worsening shoulder or scapula pain with or without weakness in that upper extremity. Pancost Tumor
21 Brachial Plexiopathopy
22 Horner s Syndrome On one side of the face Small pupil Droopy eyelid Inability to sweat
23 Superior Vena Cava Syndrome Swelling of the face and upper extremity on one side
24 Hypertrophic Osteoarthropathy Severe joint and surrounding soft tissue swelling.
26 DIAGNOSIS Chest X-ray CT scan PET scan Mediastinotomy
27 TREATMENT Curative intent vs. palliation Surgery Radiation therapy Chemotherapy
28 Breast & Colon Cancer Prevention Kieva L. Bland, M.D Meyers Detroit, MI
29 Breast Cancer Prevention No one can prevent Breast Cancer Measures can be taken to reduce risk Most important to know your pre-existing risk factors
30 Risk Factors Female Age Family History 1 st degree (mother, sister, father, brother) Genetic predisposition ( e.g. BRCA gene determined by testing) Estrogen Exposure Menarche (when periods started) Menopause (when periods ended) Hormone Replacement therapy Pregnancies Breast biopsies with abnormal results Previous History of Breast Cancer
31 Screening Knowing your risks encourages proper screening. Recent recommendations advocating a change in screening to mammograms starting at age 50 and only every 2 years are NOT being adopted by the major organizations involved in breast cancer care.
32 American Cancer Society Breast Cancer Screening Recommendations Yearly mammograms are recommended starting at age 40 and continuing for as long as a woman is in good health. Clinical breast exam (CBE) should be part of a periodic health exam, about every 3 years for women in their 20s and 30s and every year for women 40 and over. Women should know how their breasts normally feel and report any breast change promptly to their health care providers. Breast self-exam (BSE) is an option for women starting in their 20s.
33 American Society of Breast Surgeons The American Society of Breast Surgeons is strongly opposed to the recommendations released November 16, 2009 by the United States Preventive Services Task Force (USPSTF). The Society will continue to advocate for routine annual mammography screening for all women beginning at age 40. Mammography screening reduces breast cancer mortality and saves lives.
34 Healthy Living = Risk Reduction Maintain Healthy Weight Exercise Regularly Avoid excessive fat intake, especially saturated fats (meat fat) Eat fruits and vegetables for antioxidants Avoid excessive alcohol Vitamin D and multivitamins
35 High Risk Patients Your physician can calculate your risk based on a few simple questions. If you are high risk then there are other methods to reduce your risk as well. Chemoprevention (with medications) Surgery (in appropriate cases)
36 Remember Breast cancer cannot be prevented but the risk for developing it can be reduced. Screening (mammograms and breast exams) detects breast cancer at earlier stages which increases survival. Stage 5-year Relative Survival Rate 0 100% I 100% II 86% III 57% IV 20%
37 Colorectal Cancer Prevention
38 Colorectal Cancer Risk Factors Diet (Red meat, high fat, low fiber, excessive consumption of meats cooked at very high temperatures) Sedentary lifestyle Overweight Smoking Excessive alcohol use Type 2 Diabetes
39 Colorectal Cancer Risk Factors Some risk factors are out of your control: Age Ulcerative Colitis Crohn s Disease Development of Polyps Genetic predisposition for polyp syndromes or cancer
42 How do you screen for colorectal cancer? Have your stool checked for blood every year Get a colonoscopy/sigmoidoscopy every 5-10 years Other tests available include: Barium enemas Virtual Colonoscopy by CT scan
44 Colonscopy can actually prevent cancer if polyps are removed that have cancerous potentional. Getting regularly scheduled screening can potentially prevent cancer development or improve survival if diagnosed by catching at an earlier stage.
45 Risk reduction, screening, and survival go hand in hand for breast cancer and colon cancer.
About Cancer Cancer is a disease where there is a disturbance in the normal pattern of cell replacement. The cells mutate and become abnormal or grow uncontrollably. Not all tumours are cancerous (i.e.
Screening for Cancer in Light of New Guidelines and Controversies Christopher Celio, MD St. Jude Heritage Medical Group Screening Tests The 2 major objectives of a good screening program are: (1) detection
Colon and Rectal Cancer What is colon or rectal cancer? Colon or rectal cancer is the growth of abnormal cells in your large intestine, which is also called the large bowel. The colon is the last 5 feet
Prostate Cancer Screening The American Cancer Society and Congregational Health Ministry Team June Module To access this module via the Web, visit www.cancer.org and type in congregational health ministry
A.D.A.M. Medical Encyclopedia. Prostate cancer Cancer - prostate; Biopsy - prostate; Prostate biopsy; Gleason score Last reviewed: October 2, 2013. Prostate cancer is cancer that starts in the prostate
COLORECTAL CANCER SCREENING By Douglas K. Rex, M.D., FACG & Suthat Liangpunsakul, M.D. Division of Gastroenterology and Hepatology, Department of Medicine Indiana University School of Medicine Indianapolis,
Cancer Prevention Screening and Early Detection Chanphen Manosilapakorn, RN, PhD Cancer Prevention.. 1. Primary Prevention 2. Secondary Prevention 3. Tertiary Prevention Primary Prevention.. When there
Cancer Screening Robert L. Robinson, MD, MS Ambulatory Conference SIU School of Medicine Department of Internal Medicine March 13, 2003 Why screen for cancer? Early diagnosis often has a favorable prognosis
Breast cancer and genetics Cancer and genes Our bodies are made up of millions of cells. Each cell contains a complete set of genes. We have thousands of genes. We each inherit two copies of most genes,
Ana Maria Lopez, MD, MPH, FACP Professor of Medicine and Pathology Arizona Cancer Center University of Arizona Definitions Rationale Who is at risk Guidelines Breast Cancer Colorectal Cancer Prostate Cancer
All men should know they are having a PSA test and be informed of the implications prior to testing. This booklet was created to help primary care providers offer men information about the risks and benefits
CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Early Prostate Cancer:
Colorectal Cancer: Preventable, Beatable, Treatable American Cancer Society Reviewed January 2013 What we ll be talking about How common is colorectal cancer? What is colorectal cancer? What causes it?
2006, American Cancer Society, Inc. No.200700-Rev.03/08 The American Cancer Society is the nationwide community-based voluntary health organization dedicated to eliminating cancer as a major health problem
Colorectal Cancer: Preventable, Beatable, Treatable American Cancer Society Reviewed January 2016 What we ll be talking about How common is colorectal cancer? What is colorectal cancer? What causes it?
GENERAL: Breast Cancer Toolkit Marion DePuit, MSN, Faith Community Nurse Leslie Brown, BA, Community Advocate 9/2014 Understanding Breast Cancer (Adapted from the American Cancer Society and Breast Cancer.org)
Prostate Cancer Definition Prostate cancer is cancer that starts in the prostate gland. The prostate is a small, walnut-sized structure that makes up part of a man's reproductive system. It wraps around
Cancer doesn t care but we do. 2010 Cancer Annual Report The Cancer Committee of CHRISTUS St. Patrick Hospital is proud to present its 2010 Annual Report. The Community Hospital Comprehensive Cancer Program
An Introduction to PROSTATE CANCER Being diagnosed with prostate cancer can be a life-altering experience. It requires making some very difficult decisions about treatments that can affect not only the
Prostate Cancer Screening A Decision Guide for African Americans This booklet was developed by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). Published
Page 1 of 5 Prevention Checklist for Men Great progress has been made in cancer research, but we still don t understand exactly what causes most cancers. We do know that many factors put us at higher risk
Public Outcomes Report Lung Cancer Submitted by Omar A. Majid, MD Lung cancer is the most common cancer-related cause of death among men and women. It has been estimated that there will be 226,1 new cases
Understanding Pancreatic Cancer Understanding Pancreatic Cancer The Pancreas The pancreas is an organ that is about 6 inches long. It s located deep in your belly between your stomach and backbone. Your
1. What is the prostate-specific antigen (PSA) test? Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland. The PSA test measures the level of PSA in the blood. The doctor
The 2014 Cancer Program Annual Public Reporting of Outcomes/Annual Site Analysis Statistical Data from 2013 More than 70 percent of all newly diagnosed cancer patients are treated in the more than 1,500
CANCER SCREENING Dr. Tracy Sexton (updated July 2010) What is screening? Screening is the identification of asymptomatic disease or risk factors by history taking, physical examination, laboratory tests
Cancer is a group of more than 100 related diseases. Normally, cells grow and divide to produce more cells to keep the body healthy. Sometimes, this process goes wrong. New cells form when the body doesn
1 ACUTE MYELOID LEUKEMIA (AML), ALSO KNOWN AS ACUTE MYELOGENOUS LEUKEMIA WHAT IS CANCER? The body is made up of hundreds of millions of living cells. Normal body cells grow, divide, and die in an orderly
Ali A. Kader, S. (2010). Breast cancer awareness for women and men. UCQ Nursing Journal of Academic Writing, Winter 2010, 70 76. BREAST CANCER AWARENESS FOR WOMEN AND MEN by Samar Ali A. Kader Two years
Male Breast Cancer Introduction Breast cancer is cancer that starts in the cells of the breast. Breast cancer happens mainly in women. But men can get it too. Many people do not know that men can get breast
Breast Cancer Screening The American Cancer Society and Congregational Health Ministry Team October Module To access this module via the Web, visit www.cancer.org and type in congregational health ministry
An estimated 220,000 women in the United States are diagnosed with breast cancer each year, and one in eight will be diagnosed during their lifetime. While breast cancer is a serious disease, most patients
Slide 1 Breast Cancer American Cancer Society Reviewed October 2015 Slide 2 What we ll be talking about How common is breast cancer? What is breast cancer? What causes it? What are the risk factors? Can
Thymus Cancer Introduction Thymus cancer is a rare cancer. It starts in the small organ that lies in the upper chest under the breastbone. The thymus makes white blood cells that protect the body against
WhatisBreastCancer? A disease where cancer (malignant) cells form in the breast tissue and grow into a tumor Women are more prone to breast cancer than any other type of cancer Men can get breast cancer
Mammography AND CLINICAL BREAST EXAMS WHAT YOU SHOULD KNOW ABOUT BREAST CANCER HOW TO DO A BREAST SELF-EXAM joytolife.org EARLY DETECTION SAVES LIVES As a woman, you face many special concerns that call
Patient information from the BMJ Group Bowel cancer: should I be screened? Bowel cancer is a serious condition, but there are good treatments. Treatment works best if it's started early.to pick up early
Breast Cancer Epidemiology i in China JESSE HUANG ( 黄 建 始 ),MD,MHPE,MPH,MBA Professor of Epidemiology Assistant President Chinese Academy of Medical Sciences Peking Union Medical College Medical Center
Page 1 of 8 Prevention Checklist for Women Great progress has been made in cancer research, but we still don t understand exactly what causes most cancers. We do know that many factors put us at higher
Lung Cancer Awareness Month Update Guest Expert: Frank, MD Professor of Thoracic Surgery Lynn, MD Professor of Pulmonary Medicine www.wnpr.org www.yalecancercenter.org Welcome to Yale Cancer Center Answers
20 MOST FREQUENTLY ASKED QUESTIONS ABOUT COLON CANCER ANSWERED What causes a polyp to form? The exact causes of polyps are uncertain, but they appear to be caused by both inherited and lifestyle factors.
PCA3 DETECTION TEST FOR PROSTATE CANCER DO YOU KNOW YOUR RISK OF HAVING CANCER? PCA3 DETECTION TEST FOR PROSTATE CANCER There is a range of methods available to your healthcare professional to verify the
25 Breast Cancer Myths 1 Differentiating the myths from the facts about breast cancer may help to save your life. Here are 25 common myths about Nobody in my family has cancer, so I will not get Less than
Health Factsheet February 27, 2013, INP-13-1 A Publication of the National Registry of Diseases Office, Singapore Trends of Colorectal Cancer in Singapore, 2007-2011 1. Introduction The large intestine
CANCER FACTS for the Asian American Community ASIAN AMERICAN HEALTH INITIATIVE Department of Health and Human Services Montgomery County ABOUT THE ASIAN AMERICAN HEALTH INITIATIVE ASIAN AMERICAN HEALTH
Official reprint from UpToDate www.uptodate.com 2013 UpToDate The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek
SCREENING FOR THE BIG THREE CANCERS: BREAST, CERVICAL and COLORECTAL See your doctor for screening advice SCREENING FOR THE BIG THREE CANCERS: BREAST, CERVICAL and COLORECTAL Cancer is a serious, dreaded
2012 Edition The American Cancer Society is pleased to be working with your company to provide information and messages for your employees who may be facing breast cancer, as well as tips to help employees
Lung Cancer Know how to stay strong What is cancer? 2 Cancer is a disease when some cells in the body grow out of control Normal cells Your body has many tiny cells and keeps making new cells to keep you
Follow-up care plan after treatment for breast cancer A guide for General Practitioners This leaflet provides information for GPs on the follow-up care required by women who had breast cancer. It is for
Screening for Prostate Cancer It is now clear that screening for Prostate Cancer discovers the disease at an earlier and more curable stage. It is not yet clear whether this translates into reduced mortality
Sinclair Community College, Division of Allied Health Technologies Health Promotion for Community Health Workers Cardiovascular disease, stroke, and cancer Class #12 Colorectal, skin, and prostate cancer
Prostate Cancer Screening Bruce L. Houghton, MD Associate Professor of Medicine Division of General Medicine Department of Internal Medicine Creighton University School of Medicine http://en.wikipedia.org/wiki/image:prostatelead.jpg
Alabama Cancer Facts & Figures 2011 1.800.227.2345 cancer.org Have questions about cancer? Cancer information specialists are available 24 hours a day, 7 days a week. Call the American Cancer Society at
Aon Kenya Insurance Brokers Ltd Aon Hewitt Healthcare Division Breast Cancer Awareness Month Issue 12 October 2015 In this Issue 2 Cancer Statistics in Kenya 3 What is Breast Cancer? 4 Symptoms of Breast
ESSENTIALS Breast Cancer Take things one step at a time. Try not to be overwhelmed by the tidal wave of technical information coming your way. Finally you know your body best; you have to be your own advocate.
Ovarian Cancer in Georgia, 1999-23 Georgia Department of Human Resources Division of Public Health Acknowledgments Georgia Department of Human Resources......B. J. Walker, Commissioner Division of Public
Lung Cancer Introduction Lung cancer is the number one cancer killer of men and women. Over 165,000 people die of lung cancer every year in the United States. Most cases of lung cancer are related to cigarette
PROSTATE CANCER 1. Guidelines for Screening Risk Factors Normal-risk men: No family history of prostate cancer No history of prior screening Not African-American High-risk men: Family history of prostate
Ovarian Cancer 2 OVARIAN CANCER IS A MAJOR CAUSE OF MORBIDITY AND MORTALITY IN WOMEN by Name of Student HTHSCI 1110 WEBER STATE UNIVERSITY Ogden, Utah Instructor s Name Date Ovarian Cancer 2 Background
DISCOVERY HEALTH MATTERS Breast cancer the facts Vol 12 2013 Discovery Health Matters Discovery Health Matters is a layman s guide to important, but often misunderstood topics in healthcare. The information
Today s Woman Staying Healthy Risk Factors and Warning Signs for Women s Cancers Women s Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute WHAT IS A GYNECOLOGIST, AND WHAT DOES
Non-Small Cell Lung Cancer Therapies Guest Expert: Roy, MD, PhD Assistant Professor of Therapeutic Radiology Scott, MD Assistant Professor of Medical Oncology www.wnpr.org www.yalecancercenter.org Welcome
Breast Cancer Presentation by Dr Mafunga Breast cancer in the UK Breast cancer is the second most common cancer in women. Around 1 in 9 women will develop breast cancer It most commonly affects women over
Understanding Your Risk of Ovarian Cancer A WOMAN S GUIDE This brochure is made possible through partnership support from Project Hope for Ovarian Cancer Research and Education. Project HOPE FOR OVARIAN
An Introduction to Cancer and Basic Cancer Vocabulary Marc B. Garnick, MD Beth Israel Deaconess Medical Center Harvard Medical School, Boston Medical Director Cancer Programs Northeast Hospital Corporation,
AFTER DIAGNOSIS: PROSTATE CANCER Understanding Your Treatment Options INTRODUCTION This booklet describes how prostate cancer develops, how it affects the body and the current treatment methods. Although
Are you worried about prostate cancer? 1 Are you worried about prostate cancer? This information is from the leaflet Are you worried about prostate cancer? You may find the full leaflet helpful. We can
Cancer Health Cancer is not one disease, but a class of diseases characterized by uncontrolled cell division and the ability of those cells to invade other cells. Only a few decades ago many people thought
Saving healthcare costs by implementing new genetic risk tests for early detection of cancer and prevention of cardiovascular diseases Jeff Gulcher, MD PhD Chief Scientific Officer and co-founder decode
Colorectal Cancer Care A Cancer Care Map for Patients Understanding the process of care that a patient goes through in the diagnosis and treatment of colorectal cancer in BC. Colorectal Cancer Care Map
Cornell University Program on Breast Cancer and Environmental Risk Factors in New York State (BCERF) May 2002 Diet and Lifestyle and Survival from Breast Cancer While diet and lifestyle have been associated
Reduce Your Risk of Breast Cancer Reduce Your Risk of Breast Cancer There was no history in my family. But the test was positive and it was breast cancer. I was so shocked, I couldn t believe it. ~ Colette
TOPIC: Using Video to Kill Lung Cancer REPORT: MB #4111 MEDICAL BREAKTHROUGHS RESEARCH SUMMARY BACKGROUND: Lung cancer is the second most common cancer in both men and women, excluding skin cancer. About
Cancer Screening and Early Detection Guidelines Guillermo Tortolero Luna, MD, PhD Director Cancer Control and Population Sciences Program University of Puerto Rico Comprehensive Cancer Center ASPPR Clinical
Breast Cancer Introduction Cancer of the breast is the most common form of cancer that affects women but is no longer the leading cause of cancer deaths. About 1 out of 8 women are diagnosed with breast
PATIENT EDUCATION patienteducation.osumc.edu Lung Cancer: Diagnosis, Staging and Treatment Cancer begins in our cells. Cells are the building blocks of our tissues. Tissues make up the organs of the body.