PHARMINTECH NEVER STOP INNOVATION. BOLOGNA, APRIL 2016

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1 PHARMINTECH NEVER STOP INNOVATION. BOLOGNA, APRIL 2016

2 More and more effective. More representative. More necessary. The international exhibtion dedicated to the pharmaceutical, parapharmaceutical and nutraceutical industry celebrates its 15 th anniversary in excellent health. The previous edition, in 2013, saw the participation of 350 exhibitor companies, including the main international players in the sector, displaying everything that goes into the making, packaging and distribution of pharmaceutical products for health and wellness. KEEP BEATING PHARMINTECH Pharmintech is the main showcase for the latest developments of the Italian pharmaceutical industry, that is to say, THE STRONG HEART OF ITALY S PHARMACEUTICAL INDUSTRY. Italy s only industrial sector whose output has been steadily increasing over the last five years and investment levels have remained high. There is a welcome turn of events: the fifth edition will take place during the Pharma Week, from 13 to 15 April 2016, alongside Nuce, Food-Ing and Cosmofarma. In this manner, the entire supply chain for the pharmaceutical world will converge into a unified rendezvous Starting with this edition, during the Pharma Week, the Healthcare Industry Association (ASIS) will organise at BolognaFiere a new meeting focusing innovation in this sector, thereby contributing to enrich the program of the event even further. NUCE raw materials for the nutraceutical and cosmeceutical industry FOOD-ING ingredients for functional foods and the food industry COSMOFARMA health care, beauty care and services for the pharmacy ASIS, Healthcare Industry Association PHARMINTECH: AUTHENTIC REFERENCE PLATFORM FOR THOSE WISHING TO GROW AND SEIZE NEW OPPORTUNITIES AT INTERNATIONAL LEVEL. When you compete on the international stage, many factors come into play: the courage to accept daily challenges, the expertise to be able to face up to them with our heads held high, and, first and foremost, creativity, the key element to generate innovation. To be truly competitive, to really make the difference, what we create has to be systematized. Indeed, this is the only way to create value. This is what Pharmintech is all about: the ideal venue where Italy s entire pharmaceuticals supply chain can get together and interface with Pharma players at international level. A highly prestigious stage where excellence lies in taking to the stage. SERGIO DOMPÉ PRESIDENT OF PHARMINTECH 2016

3 KEEP ATTRACTING The 350 exhibitors of the last edition, just under 40% of them from foreign countries, were unanimous in recognising the selectivity and the efficacy of the event, in terms of business opportunities, relations and visibility. KNOWING, UNDERSTANDING AND MEETING THE CHALLENGES OF THE SECTOR. Pharmintech has been traditionally flanked by a rich program of international meetings, seminars and workshops that promote valuable relationships between the academic world and the industrial world. 2016: NEW TECHNOLOGY FOCUS. Besides the conference, ad hoc display sections will address the issue of pharmaceuticals counterfeiting, which is being discussed in many quarters. The proposals formulated by the exhibitors will be showcased. NEW VISITORS FOR NEW MARKETS. IN THE COMING YEARS, SALES OF GENERIC PHARMACEUTICALS IN EUROPE ARE EXPECTED TO GROW BY NO LESS THAN 10%. IN ITALY THE RATE OF GROWTH WILL BE EVEN HIGHER, AS MANY PATENT RIGHTS ARE GOING TO EXPIRE. At Pharmintech you will find all the people that count in the international business community. And those who attend have decision-making power: this means being able to do new business and lay the foundations for long-term relationships, generating fresh opportunities with each new edition. PROFILE OF THE VISITOR The 2013 edition attracted just under 5,000 trade operators. The typical visitor is: highly qualified; interested in finding new technology and management solutions; works in the production or marketing sector; has appreciable decision-making power. The international Drug Anti-Counterfeiting Conference: a worldwide network of collaboration and improvement, established with ISPE Italy Affiliate and PDA Italy Chapter in April 2013, was followed in 2015 by the conference on Serialization and Goods Distribution Practices: regulatory impacts, opportunities and critical issues for pharmaceuticals manufacturers and distribution chains. A synthesis of the themes addressed will be made in 2016, during the Pharmintech opening period, when the opportunities and criticalities associated with serialization and GDP will be examined by all the players involved in the supply chain, from the manufacturers to the pharmacies. The task of examining specific themes more closely is entrusted to Pharmintech Observatory, a jewel in the crown for the sector, established with the support of the most authoritative pharmaceutical associations, and a source of high-quality information. Making the production systems more intelligent and more effective, with easy to plan management and maintenance modalities, is one of the objectives envisaged for the factories of the future (Industry Project 4.0). In the pharmaceutical sector, this can only be achieved by drawing on an enormous quantity of data, which the companies must store for many years: at Pharmintech 2016, this issue will be addressed by exploring the numerous solutions developed to ensure data security and traceability. Starting 2016, a new Pharma Waste section will present solutions for the management and disposal of pharmaceutical waste. In 2016, the Union of Italian Manufacturers of Packaging Machinery (UCIMA) will become an organising partner of the event. Besides enriching the program of the conferences, UCIMA brings with it the involvement of the packaging machines and materials sector. FIELDS OF ACTIVITY OF THE VISITORS PHARMACEUTICALS NUTRITIONALS FUNCTIONAL FOODS PARAPHARMACEUTICALS PERSONAL CARE MEDICINE/HOSPITALS FINE CHEMISTRY BIOTECHNOLOGIES VETERINARIANS OTHER ORIGIN OF THE VISITORS BY GEO-ECONOMIC AREA Latin America South Asia Far East Middle East and North Africa 5% 4% 6% Other COUNTRIES OF ORIGIN OF THE VISITORS (65 DIFFERENT COUNTRIES, THE TOP TEN OF WHICH ARE LISTED BELOW) SWITZERLAND GERMANY RUSSIA SPAIN POLAND CHINA GREAT BRITAIN SLOVENIA FRANCE TURKEY POSITIONS OF THE VISITORS IN THEIR COMPANIES Other 28% Managing Director General Manager 6% 32% Technician 35% 9% 9% 6% 5% 5% 4% 3% 24% 30% East Europe and the Caucasus 41% Western Europe 9% 8% 5% 5% 4% 4% 4% 3% 3% Self-employed Professional Owner/Chairman 13% 14% Manager

4 COMMUNICATION IS SYNONYMOUS WITH GROWTH. BOLOGNA HOSTS THE MOST PRESTIGIOUS EVENTS OF THE PHARMACEUTICAL WORLD ALL EXHIBITION SECTORS, YOURS TOO. KEEP TRACING Besides the square metres where to showcase their products, Pharmintech exhibitors secure for themselves a unique container, which gets their ideas across in a strategic and accurate matter, before, during and after the event. The promotion campaign of Pharmintech 2016 includes: In 2016, the Bologna Trade Fair District one of Europe s most active and prestigious exhibition centres in Europe will host several complementary and mutually connected events: Pharmintech, an event of international standing for the technology supply chain in the service of the pharmaceutical, parapharmaceutical and nutraceutical industry. PROCESSING AND PACKAGING MACHINES FOR THE PHARMACEUTICAL AND PHARMACEUTICAL INDUSTRY Process machines Container treatment machines Packaging and filling machines End-of-line machines Labelling, coding, marking, traceability and RFID systems Material handling systems Sterilisation systems Automatic cleaning systems Process fluid production systems COMMUNICATION GOING YOUR WAY. press campaigns on trade magazines, in Italy and abroad; road shows and press conferences; at major international events; direct marketing actions; a dedicated, continuously updated website; newsletters; invitations to selected, highly qualified international buyers; sponsorships of conferences and benchmarking events for the pharmaceutical industry. PHARMINTECH AND AFI: A VALUABLE SYNERGY Pharmintech s collaboration with the Pharmaceutical Association Industry-Scientific Society, which has given its patronage to the event since its first edition, translates into an ongoing synergy of mutual support and the careful and strategic scheduling of the respective events: the AFI Symposium, a three-day conference of high scientific quality, that takes stock of the latest developments in the pharmaceutical sector, and Pharmintech, the not-to-be missed triennial event on technological innovation. SALONE INTERNAZIONALE PER L INDUSTRIA NUTRACEUTICA, COSMECEUTICA, FUNCTIONAL FOODS & DRINKS E HEALTH INGREDIENTS 3RD EDITION - THE INTERNATIONAL TRADE EXHIBITION PHARMA WEEK: SALONE INTERNAZIONALE PER L INDUSTRIA NUTRACEUTICA, COSMECEUTICA, FUNCTIONAL FOODS & DRINKS E HEALTH INGREDIENTS SALONE INTERNAZIONALE E CONFERENZA SUGLI INGREDIENTI FOOD & BEVERAGE 3RD EDITION - THE INTERNATIONAL TRADE EXHIBITION THE INTERNATIONAL TRADE EXHIBITION SALONE INTERNAZIONALE E CONFERENZA SUGLI INGREDIENTI FOOD & BEVERAGE THE INTERNATIONAL TRADE EXHIBITION These exhibitions are able to mutually increase the flow of visitors: a convergence that helps generate synergetic effects and contacts across the board, which will be further enhanced by the ASIS Conference on the innovation in the sector. With Pharmintech, Nuce, Food-Ing and ASIS, to take place from 13 to 15 April, and Cosmofarma, from 15 to 17 April, Bologna will host the pharmaceutical world for an entire week. Pharmintech, Nuce, Food-Ing and ASIS will take place at the same time as Cosmofarma on Friday 15 April MATERIALS, PACKAGING MATERIALS AND CONTAINERS Packaging materials and containers of all types for primary, secondary and tertiary packing Sealing and sealing materials Devices (droppers, dispensers, atomisers, vaporisers, valves, etc.) Countertop and self-standing displays, multipacks, etc. Packaging materials Ancillary equipment and materials for packaging (glue, ink, enamel, paint, etc.) Accessories for packing and packaging (labels, ropes, ribbon, string, etc.) ANCILLARY EQUIPMENT, ACCESSORIES AND COMPONENTS Pharmaceutical equipment Automation and instrumentation systems PHARMACEUTICAL AND PHARMACEUTICAL RAW MATERIALS Active principles for pharmaceutical use Ingredients Excipients INFRASTRUCTURES, SYSTEMS AND LOGISTICS Production areas Production departments with classified (sterile) areas and unclassified areas Control equipment and systems Electrical systems Architectural finishes Environmental monitoring and personal safety Consumables and personal protective equipment HVAC systems Utilities and piping Warehousing, storage and material handling system Dust abatement Emission control Water treatment systems Effluent treatment systems Environmental hygiene and production safety SECURITY AND DATA, DOCUMENT AND INFORMATION PROTECTION SYSTEMS Anti-counterfeiting Anti-malware Application security Access authorisation systems Investigation/industrial counterintelligence systems SERVICES Formulation development Analyses Production and packaging Clinical studies Information systems INFRASTRUCTURE MAINTENANCE AND MANAGEMENT Design and engineering services Consultancy, certification and regulatory activities Validation Training Marketing and Communication/Packaging design Technical publications Trade associations Regulatory and public entities

5 THE EXHIBITORS AT PHARMINTECH 2013 A.C.E.F. Spa - A.M. Instruments Srl - A.M.D Electronic Srl - Adamus HT Sp. z o.o. - Aerre Inox Srl - AFI - Agierre Sas - Alfa Laval Spa - All Fill Int. Ltd. - All Pack Hellas - Allegri - Cesare Spa - Allen Coding Systems, A Division of ITW Espana - Allpaq Packaging Limited - ALS Srl - Amixon GmbH - Anhui Huafeng Pharmaceutical Rubber Co. Ltd. - Antares Vision Srl - Aps Domino - Arca Etichette Spa - Arda Natura Srl Unipersonale - Ascca - Aschimfarma-Federchimica - Asco Filtri Srl - Atag Spa - Atlas Copco Italia Spa-Div. Compressori - Ats Ag Automatic Taping Systems - Ava - Huep GmbH & Co. Kg - Awh Armaturenwerk Hötensleben GmbH - Axomatic Srl - Azo GmbH & Co. Kg - B & D Italia Srl - Baumer Hhs Srl - Bausch+Ströbel Maschinenfabrik - Bäuerle Mathias GmbH - Be- Ma Editrice - Bea Technologies Spa - Belimed Deutschland GmbH - Berardi Bullonerie Srl - Biopharmanet Tec - Bolondi Ivano Off. Mecc. - Bona Europe - Pharmaceutical Delivery Systems - Bosspak - Brevetti Angela Srl - Brt Corriere Espresso - Bürkert Contromatic Italiana Spa - C.E.I.A. Spa - Camfil Spa - Cangzhou Four-Star Glass Tube Co. Ltd. - Cargill Srl-Divisione Texturizing Solutions - Cariba Srl - Carpidraulic Srl - Cgk Solutions Srl Unipersonale - Chargepoint Technology Limited - Charles Ischi AG-Pharma-Prüftechnik - China National Pharmaceutical Packaging Association - China-Pharm - Cicrespi Spa - Cipack - Clean-Tech System - Cmp Di Pilastro Srl - CO.RA Srl - CO.RI.MA. Srl - Colombo Filippetti Spa - Com.Pack - Comas Srl - Comecer Spa - Consorzio Tefarco Innova - Contec Inc. - Contego Packaging Italy Srl - Conter Srl - Convel Srl - Convertec AB - Corti Domenico Srl - Cosmoprof-Responsible Make Up - Costamac di F.lli Gerosa Srl - CPA-Associazione Produttori Chimico Farmaceutici Generici - Crane Process Flow Technologies Srl - CSV Life Science Srl - CT Meca Srl - CTP System - D.C.M. Srl - D.P.R. Srl - d.velop Life Sciences GmbH - Dam Raccordi Srl - Delta 2000 Srl - Dg Italia Srl - Diosna Dierks & Söhne GmbH - Domino Uk Ltd. - Dott. Bonapace & C. Srl - Durst Phototechnik Spa - E.LIAS - East Afripack Editores Industriales SA de CV/Esensa - Efaflex GmbH & Co. Kg - Eidos Spa - Elexind Srl - Elmiti Srl - Endeavour - Eyec Italia - Enercon Industries Ltd. - Energy Group Srl - Eon Srl - EPM - European Pharmaceutical Manufacturer - Etimex Primary Packaging GmbH - Eurek Srl - Evonik Industries GmbH - F.H. Papenmeier GmbH & Co. KG - F.P.E Srl - F.P.S. Food And Pharma Systems Srl - Faber Srl - Famar Packaging Srl - Farmindustria - Farmo Res Srl - Fasinternational Srl - Fedegari Autoclavi Spa - Festo Spa - Fette Compacting GmbH - Fike Europe Bvba - Fitzpatrick Company Europe - Fluid-Bag Ltd. - Fm Engineering Srl - Frewitt S.A. - Frymakoruma AG - G.F. Spa - G.S. Divisione Verniciatura Srl - Gammarad Italia Spa - Gammatom Srl - GE Analytical Instruments - GEA Lyophil GmbH - GEA Pharma Systems-Courtoy - Gebr. Rieger GmbH + Co. KG - Gerteis Maschinen + Processengin. AG - Giorgio Bormac Srl - Gisi - Glatt GmbH - Global Vision Inc. - Gradient.Systemintegration GmbH - GTO Srl - Guk-Falzmaschinen Griesser & Kunzmann GmbH & Co. KG - Halstrup-Walcher GmbH - Hapa AG - Harro Höfliger Verpackungsmaschinen GmbH - Herberts Industrieglas GmbH & Co. KG - Hiwin Technologies Corp. - Hpt-Hochwertige Pharmatechnik GmbH - HSA Systems ApS - H.T. High Technology Srl - I Holland Ltd. - ICF-Rivista dell'industria Chimica e Farmaceutica - ICP-Rivista dell'industria Chimica - Idroinox Impianti Srl - IMA Spa - Industrie Pharma Magazine - Infinitec Activos S.L. - Infor GmbH - Inkdustry GmbH - Innojet Herbert Hüttlin - Inox Italia Srl - Inoxpa Italia Srl - Ipack-Ima Ipack-Ima Spa - IPI-International Pharmaceutical Industry - IPMMA- Indian Pharma Machinery Manufacturers Association - ISI Plast Spa - Isolab Laborgeräte GmbH - Ispe Affiliata Italia - Istituto Italiano Imballaggio - Italia Imballaggio - Iteco Srl - Item Srl - ITW Contamination Control - Jiangsu Lefan Capsule Co. Ltd. - Jung Gummitechnik GmbH - Kaeser Compressori Srl - Kallik Ltd. - Kevac Srl - Kimberly-Clark Srl - Korsch AG - Kraus Maschinenbau GmbH - La.Ser Di Fumagalli Giovanna & C. Sas - Labelpack Srl - Laetus Italia Srl - Leanbox Srl - Lee Spring Limited - Leibinger Paul GmbH & Co. KG - Leonhard Weiss Fussbodentechnik GmbH - Lighthouse - Lirmaprint Srl - LKE GmbH - Lock Inspection Systems BV - Loma Systems - M.P.A. Srl Macofar - Manes Macchine Srl - Manifattura Tubi Gomma Spa - Mapei Spa - Mar Cor Purification - Marchesini Group Spa - Marking Products Srl - Marta Srl - Matling Srl - Medical Business PBL - Mesa Laboratories Inc. - MG2 Srl - Miele Italia Srl - MK Versuchsanlagen Inh. Michael Keil - Monolab Srl - Mulser Srl - Multi Import Srl - Müller GmbH - Naf-Vsm BV - Nemesis Srl - Neoceram S.A. - Neri Labels Srl - Neri Spa - Neue Verpackung - Neumo-Egmo Spain S.L. - Nicomac Europe Srl - Nilfisk-Cfm Spa - Nimax Spa - Nitritex Ltd. - Noack - Nuova Guseo Srl - Nuova Ics Automazione Srl - Nuova Ompi-Stevanato Group - O'hara Technologies Inc. - O.M.A.R. Di Cericola Giorgio - O.ZA.F. Srl - OCS Checkweighers GmbH - Off. Mecc. F.lli Ronchi Srl - Officine Laborall Srl - Omag Srl - Omas Tecnosistemi Srl - Optima Group Pharma GmbH - Packaging Argentino - Packaging Journal - Packlab Srl - Packtech Middle East & North Africa - Padana Cleanroom Srl - Palladio Zannini Industrie Grafiche Cartotecniche Spa - Parker Hannifin Manufacturing Srl - Parteco Srl - Particle Measuring Systems Srl - Pda Europe-Italy Chapter - Perfect Pack Srl - Permax Srl - Pet-Power Bv - Phaba Srl - Pharma Quality Europe Srl - Pharma Technology S.A. - Pharmaceutical & Cosmetic Review - Pharmaceutical Industry Review - Pharmaceutical Technology Europe - Pharmacontrol Electronic GmbH-Mettler Toledo Group - Phenbiox - Piab Italia Srl - Pilot Italia Spa - Plümat Maschinenbau Vertriebs GmbH - Pohling Srl - Prisma Industriale Srl - Process - Promatic - Promedia Srl - Recodi Tecnology Srl - Remoin Srl - Rensa Di Alberto Monti - RG Strumenti Srl - Riera Nadeu S.A. - Roboqbo Srl - Romaco Pharmatechnik GmbH - Romaco Srl - Rommelag AG - Rotronic Italia Srl - RS High Tecnology Food - Russell Finex Ltd. - S.D.S. Srl - S.I.A. Srl - Sagicofim Spa - Scanware Electronic GmbH - Seidenader Maschinenbau GmbH - Sepha Ltd. - Servolift GmbH - Shandong Pharmaceutical Glass Co. Ltd. - Shield Medicare Ltd.-A Division of Ecolab - Siebler - Sika Italia Spa - SIS.MA Srl - SO.CO.TIS. Spa - Soitra Spa - Solaris Laser Sa - SPC Manufacturing - Speciality Chemicals Magazine - Stäubli Italia Spa - Stericheck Consulting Srl - Steriline Srl - Steritek Srl - Sterivalves Srl - Stratasys Ltd. - Studio Svimm-Farmaffari - Svet Baleni' - System Logistics Spa - Sytech Srl - T.E.CO Srl - Tablets & Capsules - Taim Srl - Techniconsult Firenze Srl - Techpharma Srl - Tecniche Nuove Spa - Tecninox Srl (Noceto, PR) - Tecninox Srl (Origgio, VA) - Tecno Pharma - Tekna Parma Srl - Telesis Europe B.V. - Tema Sinergie Srl - Terruzzi Fercalx Spa - Tgm-Tecnomachines Srl - The World of The Pharmaceutical Industry - Thermo Fisher Scientific Div. Barnant Company - Thermo Ramsey Italia Srl - Tiger-Vac Europa Srl - Tiposervice Srl - Tisza - Texl Packaging S.A. - Todini Codifica Industriale Srl - Toppy Srl - Uhlmann Pac-Systeme Bmgh & Co. - Unipac - Università degli Studi del Piemonte Orientale-Dipartimento di Scienze del Farmaco - Università degli Studi dell'aquila-dipartimento Mesva - Università degli Studi di Camerino-Scuola del Farmaco - Università degli Studi di Napoli Federico II-Dipartimento di Farmacia - Università di Bologna-Dipartimento di Farmacia e Biotecnologie - Università di Milano-Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche - Università di Padova-dipartimento di Scienze del Farmaco - Università di Parma - Università di Pisa-Dipartimento di Farmacia - Università di Roma Sapienza-Dipartimento di Chimica e Tecnologie del Farmaco - V2 Engineering Srl - Valmatic Srl - Venair Srl - Veolia Water Solutions & Technologies Italia Srl - Videojet Italia Srl - Videojet Technologies Inc. - Vis Viva Srl - VR-Verpackungs Rundschau - Warex Valve GmbH - Watson Marlow Srl - Wilco AG - Wipotec Italia Srl Wolke - Wright Flow Technologies Ltd. - Yellow & Yellow Srl - Yokogawa Italia Srl - Zuma Srl BOLOGNA, APRIL Organising Committee: So.Ge.Cos. spa - via Cappuccini 2 Milan, Italy Organised by: In conjunction with: With the patronage of:

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