Yusri uso of'", Mohd Noor Hakim ~arnson'."

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1 Manufacturing Of Biocompatible Implant Component Using Rapid :; -+2 i~ Prototyping Technology : Yusri uso of'", Mohd Noor Hakim ~arnson'." :a 5c 1 Faculty of Mechanical Engineering & Manufacturing, Universiti Tun Hussein Onn Malaysia F- (UTHM), Batu Pahat, Johor, Malaysia "usri@uthm.edu.my Keywords: Biocompatible material, Rapid Prototyping FV n a Abstract. The purpose of this research is to study the manufacturing of biocompatible i~iiplant component by using rapid prototyping technology, in particular of 3D printing process. The biocompatible material collsist of 80% cobalt-chromium-hap were prepared by mecha~~ically blended with 10% maltodextrin and 10% polyvinyl alcohol as binding mechanism for 3D printing process. Test specimens were fabricated using experimental 3D printing nlachine followed by sintering process. The characteristic of the composites were studied using various techniques including Scanning Electron Microscope (SEM and EDS), hardness test, flexural test, porosity and density lneasurement. The results show that the biocompatible cobalt implant composite can be fabricated successfully using 3D printing process. Further investigation can be carried out on the samples to sh~dy the toxicity, chemical reaclion and cell reaction for implant application. Introduction A number of medical case studies are presented, illustrating different uses of RP technology. These studies have been analyzed in terms of how the technology has been applied in order to solve related medical problems. A bone implant is a medical procedure in which a damaged or missing piece of bone is replaced with an implant. If the implant takes successfully, there is a good chance that the area will heal well, allowing the patient to use the bone as helshe nor~nally would. The requirement of the implant structure is considering on the porosity of the specinrens. To fulfill the requirement needed, the suitable technique 1s by usmg layer manufacturing technique. The implant components structure is originally in complex shape. In order to fabricated the design based on the structure, additive technique which is rapid prototyping technique is suitable than the subtractive technique. The main obiectives of this research us to_-singragid prototype process from biocornpatible materials and to evaluate the microstructure and the mechanical properties of the biocompatible material. This research focus on raw inaterial preparation for 3DP process, followed by fabrication of 3D components from biocompatible implant material and evaluation of ~nicrostruch~re and physical properties of the implant component. The results show the new implants material that suitable by using 3DP with the result of microstructure and mechanical properties product that will be use for implant surgery. The focus is directly on the fabrication sample of the biocompatible ~naterial by using 3DP process and the evaluation is only involving on microstructu~-e and mechanical properties There are many commonly commercial techniques in rapid prototype technologies. At least there are six different rapid prototyping techniques available and each with unique strengths [I]. Rapid prototyping is an additive process, combining layers of paper, wax, or plastic to create a solid object. RP's additive nature allows it to create objects with complicated internal features that cannot.,," '::';:: RIi "his reserved No pafiol mnlenlr afthis paper niay bereprodclced ortransmilled in any larm orby any means without the wonen perlnisslon otltp, wwtlp nel. (ID: ,03:42:12)

my Keywords: Biocompatible material, Rapid Prototyping FV n a Abstract.

6 30 Advanced Materials Research specimens have been successf~~lly materials regarding the result of the experiments findings is in the value range of natural human bone. The evaluation of the microstructure and the mechanical properties of the biocompatible material also shows that the material have potential and suitable in fabrication of implant by using 3DP machine. There are another experimental work is highly recom~iiended especially with regard to toxicity, fatigue resistance and biocompatibility in viva test as for a further research in this field. Acknowledgment.?l: n -. "_ " A s z 0 = - produce by using rapid prototype process from biocompatihle $ $ This research is supported under Graduate Incentive Grant (CIS), University Tun Hussein Onn Malaysia (UTHM) and Ministry of Science, Technology & lnnovation (MOSTI), Malaysia under Sciencefund Grant (Solo). Malaysia. Thanks to all team members for every support provided. 3 2 h- 0 References [I] Griffith M. John S.L (1998). "Rap~d Technologies," Rapid Prototyping hnp:il~~~.me.p~u.ed~llaman~~salme415i~pintr02 [2] N. A. Waterman, P. Dickens (1994). "Rapid Product Development in the USA, Europe and Japan". World Class Design to manufacture, Val. 1(3), pp [3] Park J.B, Bronzino J.D, (2003), "Biomaterials: principles artd applications", CRC Press, pp [4] N. Hidayah (2007). "Fabrication and Properties of Cobalt-Chromium Implant Composite". School of Materials Engineering, University Malaysia Perlis. [5] A. R. Noraini (2009). "Fabrication of cobalt implant composite (CIC) material using rapid prototyping machine (3DP) for reconstructive surgery". Final Year Project. University Tun Hussein Onn Malaysia. [6] C. Suyanarayana (2001). 'Mechanical Alloying and Milling". Prog Mater Sci 46:l-184. [7] D. I<opeliovich (2008). "Sintering of Metal". Retrieve from [8] M. P. Groover (201 0). "Fundametals of Modern Manufacturing: Materials, Processes, and Systems". John Wiley and Sons. 4th Ed. Pp [9] D. W. Hutmacher (2007). "Biomechanical Systems Technologies". World Scientific. [I 01 P. Fratzl (2008). "Collagen: Structure and Mechanics". Springer. Pp [I 11 Information on lmechlbasic - bone.htm#mechanics [I 21 R. Frigg (2008). "Textbool~ of Orthopedics and Trauma". Jaypee Brothers Publisher.

machine. There are another experimental work is highly recom~iiended especially with regard to toxicity, fatigue resistance and biocompatibility in viva test as for a further research in this field.

MANUFACTURE OF CONTROLLED DRUG DELIVERY DEVICE OF POLYCAPROLACTONE BY SELECTIVE LASER SINTERING ABSTRACT

MANUFACTURE OF CONTROLLED DRUG DELIVERY DEVICE OF POLYCAPROLACTONE BY SELECTIVE LASER SINTERING P. Klauss 1*, G. V. Salmoria 1, M. Souza 1, L. A. Kanis 2 1* Laboratory CIMJECT, Federal University of Santa